Nucleic Acid Labeling - Global Market Outlook (2020-2028)

Nucleic Acid Labeling - Global Market Outlook (2020-2028)

According to Stratistics MRC, the Global Nucleic Acid Labeling market is accounted for $2,114.25 million in 2020 and is expected to reach $4,768.02 million by 2028 growing at a CAGR of 10.7% during the forecast period. Some of the key factors propelling the market growth include increasing healthcare expenditure, increase in research and development expenditure, rise in research activities specifically in genomic research and disease diagnosis, advancements in tools for synthetic genome design, and growing demand for personalized medicine. However, lack of skilled professionals in transcriptomics is restraining the market growth.

Labeling of nucleic acids is required for multiple studies proposing to elucidate their functions and dynamics in vitro and in cells. Nucleic acids can be transformed with labels that enable their detection or purification. The resulting nucleic acid probes can be used to recognize or recover other interacting molecules. Common labels used to produce nucleic acid probes include radioactive phosphates, biotin, fluorophores, and enzymes. There are several chemical and enzymatic methods prepared for labeling nucleic acids, such as the incorporation of fluorescent tags, radioactive phosphates, and modifications with biotin, which are essentially utilized in biotechnology applications. The labeled nucleic acid is used for purposes including PCR, FISH, blotting, microarrays, DNA sequencing, and in situ hybridization.

By product, biotin-based segment is expected to be the fastest-growing segment during the forecast period, due to increased stability and their non-hazardous nature. The biotin-based labels use non-toxic materials and have faster detection rates than radioactive probes. Furthermore, owing to their long half-life and high stability, biotin-based probes can be prepared in bulk and stored at -20°C for repeated uses. There have been several advancements in biotin-based techniques, such as the addition of long tails of biotinylated nucleotides through enzymatic methods to counter the technique’s limitations.

On the basis of geography, the Asia Pacific market is expected to expand at the fastest growth rate during the forecast period, due to the emergence of local players and the increasing penetration of key players in the Asia Pacific region. The emerging companies are tapping on the opportunities by providing a wide array of labeling solutions in developing nations. Moreover, an increase in the number of inter-regional collaborations among key entities has been witnessed in this region, further propelling the market growth. These collaborations are largely being targeted towards the enhancement of nucleic acid profiling services and genomic research across the Asia Pacific countries.

Some of the key players in Nucleic Acid Labeling Market include GE Healthcare, Promega Corporation, Agilent Technologies, Inc., Thermo Fisher Scientific Inc., Enzo Biochem Inc., New England Biolabs, PerkinElmer, Inc., F. Hoffmann La-Roche AG, Merck KGaA, Vector Laboratories Inc., Marker Gene Technologies Inc., VWR International, LLC, LubioScience GmbH, Helix OpCo LLC, and Interchim.

Labeling Techniques Covered:
• Random Primer
• Nick Translation
• In Vitro Transcription
• End Labeling
• Reverse Transcription
• Terminal labeling

Products Covered:
• Services
• Reagents & Kits
• Instruments

Applications Covered:
• Southern & Northern Blotting
• Microarray
• Fluorescence in Situ Hybridization (FISH)
• In Situ Hybridization
• Deoxyribonucleic Acid (DNA) Sequencing
• Polymerase Chain Reaction (PCR)
• Oligonucleotide Labeling
• Cellular Localization

End Users Covered:
• Research Centers
• Diagnostic Centers
• Academic & Research Institutes
• Contract Research Organizations
• Pharmaceutical & Biotechnology Companies
• Hospitals/Clinics
• Therapeutics
• Laboratory
• Testing Institutions

Treatment Types Covered:
• On-Demand
• Prophylactic

Types Covered:
• Ribonucleic Acid (RNA) Labeling
• Deoxyribonucleic Acid (DNA) Labeling

Methods Covered:
• Chemical-Based
• Enzyme-Based

Sales Channels Covered:
• Distributor
• Direct Sales

Regions Covered:
• North America
US
Canada
Mexico
• Europe
Germany
France
Italy
UK
Spain
Rest of Europe
• Asia Pacific
Japan
China
India
Australia
New Zealand
South Korea
Rest of Asia Pacific
• South America
Argentina
Brazil
Chile
Rest of South America
• Middle East & Africa
Saudi Arabia
UAE
Qatar
South Africa
Rest of Middle East & Africa

What our report offers:
- Market share assessments for the regional and country-level segments
- Strategic recommendations for the new entrants
- Covers Market data for the years 2019, 2020, 2021, 2025 and 2028
- Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations)
- Strategic analysis: Drivers and Constraints, Product/Technology Analysis, Porter’s five forces analysis, SWOT analysis, etc.
- Strategic recommendations in key business segments based on the market estimations
- Competitive landscaping mapping the key common trends
- Company profiling with detailed strategies, financials, and recent developments
- Supply chain trends mapping the latest technological advancements

Free Customization Offerings:
All the customers of this report will be entitled to receive one of the following free customization options:
• Company Profiling
Comprehensive profiling of additional market players (up to 3)
SWOT Analysis of key players (up to 3)
• Regional Segmentation
Market estimations, Forecasts and CAGR of any prominent country as per the client's interest (Note: Depends on feasibility check)
• Competitive Benchmarking
Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances


1 Executive Summary
2 Preface
2.1 Abstract
2.2 Stake Holders
2.3 Research Scope
2.4 Research Methodology
2.4.1 Data Mining
2.4.2 Data Analysis
2.4.3 Data Validation
2.4.4 Research Approach
2.5 Research Sources
2.5.1 Primary Research Sources
2.5.2 Secondary Research Sources
2.5.3 Assumptions
3 Market Trend Analysis
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Application Analysis
3.8 End User Analysis
3.9 Emerging Markets
3.10 Impact of Covid-19
4 Porters Five Force Analysis
4.1 Bargaining power of suppliers
4.2 Bargaining power of buyers
4.3 Threat of substitutes
4.4 Threat of new entrants
4.5 Competitive rivalry
5 Global Nucleic Acid Labeling Market, By Labeling Technique
5.1 Introduction
5.2 Random Primer
5.3 Nick Translation
5.4 In Vitro Transcription
5.5 End Labeling
5.5.1 3' End Labeling
5.5.2 5' End Labeling
5.6 Reverse Transcription
5.7 Terminal labeling
6 Global Nucleic Acid Labeling Market, By Product
6.1 Introduction
6.2 Services
6.3 Reagents & Kits
6.3.1 Probes
6.3.1.1 Radioactive Probes
6.3.1.2 Non-Radioactive Probes
6.3.2 Labels
6.3.2.1 Non-Radioactive Labels
6.3.2.1.1 Biotin-Based
6.3.2.1.2 Digoxigenin (DIG) System
6.3.2.1.3 Fluorescent
6.3.2.1.4 Chemiluminescent
6.3.2.1.5 Antibodies
6.3.2.1.6 Enzymes
6.3.2.1.7 Flurophores
6.3.2.1.8 Streptavidin
6.3.2.2 Radioisotope/Radioactive Labels (Radioactive Phosphates)
6.4 Instruments
7 Global Nucleic Acid Labeling Market, By Application
7.1 Introduction
7.2 Southern & Northern Blotting
7.3 Microarray
7.4 Fluorescence in Situ Hybridization (FISH)
7.5 In Situ Hybridization
7.6 Deoxyribonucleic Acid (DNA) Sequencing
7.7 Polymerase Chain Reaction (PCR)
7.8 Oligonucleotide Labeling
7.9 Cellular Localization
8 Global Nucleic Acid Labeling Market, By End User
8.1 Introduction
8.2 Research Centers
8.3 Diagnostic Centers
8.4 Academic & Research Institutes
8.5 Contract Research Organizations
8.6 Pharmaceutical & Biotechnology Companies
8.7 Hospitals/Clinics
8.8 Therapeutics
8.9 Laboratory
8.10 Testing Institutions
9 Global Nucleic Acid Labeling Market, By Treatment Type
9.1 Introduction
9.2 On-Demand
9.3 Prophylactic
10 Global Nucleic Acid Labeling Market, By Type
10.1 Introduction
10.2 Ribonucleic Acid (RNA) Labeling
10.3 Deoxyribonucleic Acid (DNA) Labeling
11 Global Nucleic Acid Labeling Market, By Method
11.1 Introduction
11.2 Chemical-Based
11.2.1 Photoreaction
11.2.2 Conjugation
11.3 Enzyme-Based
12 Global Nucleic Acid Labeling Market, By Sales Channel
12.1 Introduction
12.2 Distributor
12.3 Direct Sales
13 Global Nucleic Acid Labeling Market, By Geography
13.1 Introduction
13.2 North America
13.2.1 US
13.2.2 Canada
13.2.3 Mexico
13.3 Europe
13.3.1 Germany
13.3.2 UK
13.3.3 Italy
13.3.4 France
13.3.5 Spain
13.3.6 Rest of Europe
13.4 Asia Pacific
13.4.1 Japan
13.4.2 China
13.4.3 India
13.4.4 Australia
13.4.5 New Zealand
13.4.6 South Korea
13.4.7 Rest of Asia Pacific
13.5 South America
13.5.1 Argentina
13.5.2 Brazil
13.5.3 Chile
13.5.4 Rest of South America
13.6 Middle East & Africa
13.6.1 Saudi Arabia
13.6.2 UAE
13.6.3 Qatar
13.6.4 South Africa
13.6.5 Rest of Middle East & Africa
14 Key Developments
14.1 Agreements, Partnerships, Collaborations and Joint Ventures
14.2 Acquisitions & Mergers
14.3 New Product Launch
14.4 Expansions
14.5 Other Key Strategies
15 Company Profiling
15.1 GE Healthcare
15.2 Promega Corporation
15.3 Agilent Technologies, Inc.
15.4 Thermo Fisher Scientific Inc.
15.5 Enzo Biochem Inc.
15.6 New England Biolabs
15.7 PerkinElmer, Inc.
15.8 F. Hoffmann La-Roche AG
15.9 Merck KGaA
15.10 Vector Laboratories Inc.
15.11 Marker Gene Technologies Inc.
15.12 VWR International, LLC
15.13 LubioScience GmbH
15.14 Helix OpCo LLC
15.15 Interchim
List of Tables
Table 1 Global Nucleic Acid Labeling Market Outlook, By Region (2019-2028) ($MN)
Table 2 Global Nucleic Acid Labeling Market Outlook, By Labeling Technique (2019-2028) ($MN)
Table 3 Global Nucleic Acid Labeling Market Outlook, By Random Primer (2019-2028) ($MN)
Table 4 Global Nucleic Acid Labeling Market Outlook, By Nick Translation (2019-2028) ($MN)
Table 5 Global Nucleic Acid Labeling Market Outlook, By In Vitro Transcription (2019-2028) ($MN)
Table 6 Global Nucleic Acid Labeling Market Outlook, By End Labeling (2019-2028) ($MN)
Table 7 Global Nucleic Acid Labeling Market Outlook, By 3' End Labeling (2019-2028) ($MN)
Table 8 Global Nucleic Acid Labeling Market Outlook, By 5' End Labeling (2019-2028) ($MN)
Table 9 Global Nucleic Acid Labeling Market Outlook, By Reverse Transcription (2019-2028) ($MN)
Table 10 Global Nucleic Acid Labeling Market Outlook, By Terminal labeling (2019-2028) ($MN)
Table 11 Global Nucleic Acid Labeling Market Outlook, By Product (2019-2028) ($MN)
Table 12 Global Nucleic Acid Labeling Market Outlook, By Services (2019-2028) ($MN)
Table 13 Global Nucleic Acid Labeling Market Outlook, By Reagents & Kits (2019-2028) ($MN)
Table 14 Global Nucleic Acid Labeling Market Outlook, By Probes (2019-2028) ($MN)
Table 15 Global Nucleic Acid Labeling Market Outlook, By Labels (2019-2028) ($MN)
Table 16 Global Nucleic Acid Labeling Market Outlook, By Instruments (2019-2028) ($MN)
Table 17 Global Nucleic Acid Labeling Market Outlook, By Application (2019-2028) ($MN)
Table 18 Global Nucleic Acid Labeling Market Outlook, By Southern & Northern Blotting (2019-2028) ($MN)
Table 19 Global Nucleic Acid Labeling Market Outlook, By Microarray (2019-2028) ($MN)
Table 20 Global Nucleic Acid Labeling Market Outlook, By Fluorescence in Situ Hybridization (FISH) (2019-2028) ($MN)
Table 21 Global Nucleic Acid Labeling Market Outlook, By In Situ Hybridization (2019-2028) ($MN)
Table 22 Global Nucleic Acid Labeling Market Outlook, By Deoxyribonucleic Acid (DNA) Sequencing (2019-2028) ($MN)
Table 23 Global Nucleic Acid Labeling Market Outlook, By Polymerase Chain Reaction (PCR) (2019-2028) ($MN)
Table 24 Global Nucleic Acid Labeling Market Outlook, By Oligonucleotide Labeling (2019-2028) ($MN)
Table 25 Global Nucleic Acid Labeling Market Outlook, By Cellular Localization (2019-2028) ($MN)
Table 26 Global Nucleic Acid Labeling Market Outlook, By End User (2019-2028) ($MN)
Table 27 Global Nucleic Acid Labeling Market Outlook, By Research Centers (2019-2028) ($MN)
Table 28 Global Nucleic Acid Labeling Market Outlook, By Diagnostic Centers (2019-2028) ($MN)
Table 29 Global Nucleic Acid Labeling Market Outlook, By Academic & Research Institutes (2019-2028) ($MN)
Table 30 Global Nucleic Acid Labeling Market Outlook, By Contract Research Organizations (2019-2028) ($MN)
Table 31 Global Nucleic Acid Labeling Market Outlook, By Pharmaceutical & Biotechnology Companies (2019-2028) ($MN)
Table 32 Global Nucleic Acid Labeling Market Outlook, By Hospitals/Clinics (2019-2028) ($MN)
Table 33 Global Nucleic Acid Labeling Market Outlook, By Therapeutics (2019-2028) ($MN)
Table 34 Global Nucleic Acid Labeling Market Outlook, By Laboratory (2019-2028) ($MN)
Table 35 Global Nucleic Acid Labeling Market Outlook, By Testing Institutions (2019-2028) ($MN)
Table 36 Global Nucleic Acid Labeling Market Outlook, By Treatment Type (2019-2028) ($MN)
Table 37 Global Nucleic Acid Labeling Market Outlook, By On-Demand (2019-2028) ($MN)
Table 38 Global Nucleic Acid Labeling Market Outlook, By Prophylactic (2019-2028) ($MN)
Table 39 Global Nucleic Acid Labeling Market Outlook, By Type (2019-2028) ($MN)
Table 40 Global Nucleic Acid Labeling Market Outlook, By Ribonucleic Acid (RNA) Labeling (2019-2028) ($MN)
Table 41 Global Nucleic Acid Labeling Market Outlook, By Deoxyribonucleic Acid (DNA) Labeling (2019-2028) ($MN)
Table 42 Global Nucleic Acid Labeling Market Outlook, By Method (2019-2028) ($MN)
Table 43 Global Nucleic Acid Labeling Market Outlook, By Chemical-Based (2019-2028) ($MN)
Table 44 Global Nucleic Acid Labeling Market Outlook, By Photoreaction (2019-2028) ($MN)
Table 45 Global Nucleic Acid Labeling Market Outlook, By Conjugation (2019-2028) ($MN)
Table 46 Global Nucleic Acid Labeling Market Outlook, By Enzyme-Based (2019-2028) ($MN)
Table 47 Global Nucleic Acid Labeling Market Outlook, By Sales Channel (2019-2028) ($MN)
Table 48 Global Nucleic Acid Labeling Market Outlook, By Distributor (2019-2028) ($MN)
Table 49 Global Nucleic Acid Labeling Market Outlook, By Direct Sales (2019-2028) ($MN)
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook