Prader-Willi Syndrome - Market Insights, Epidemiology and Market Forecast-2028
DelveInsight’s ‘Prader-Willi Syndrome - Market Insights, Epidemiology and Market Forecast-2028’ report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Prader-Willi Syndrome in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan.
The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Prader-Willi Syndrome (PWS) from 2017 to 2028 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.
• The United States
• EU5 (Germany, France, Italy, Spain and the United Kingdom)
Study Period: 2017-2028
Prader-Willi Syndrome - Disease Understanding
According to US National Library of Medicine, Prader-Willi Syndrome (PWS) is a complex genetic condition that affects many parts of the body. In infancy, this condition is characterized by weak muscle tone (hypotonia), feeding difficulties, poor growth, and delayed development. Beginning in childhood, affected individuals develop an insatiable appetite, which leads to chronic overeating (hyperphagia) and obesity. Some people with Prader-Willi syndrome, particularly those with obesity, also develop type 2 diabetes (the most common form of diabetes).
People with Prader-Willi Syndrome typically have mild to moderate intellectual impairment and learning disabilities. Behavioral problems are common, including temper outbursts, stubbornness, and compulsive behavior such as picking at the skin. Sleep abnormalities can also occur. Additional features of this condition include distinctive facial features such as a narrow forehead, almond-shaped eyes, and a triangular mouth; short stature; and small hands and feet. Some people with Prader-Willi syndrome have unusually fair skin and light-colored hair. Both affected males and affected females have underdeveloped genitals. Puberty is delayed or incomplete, and most affected individuals are unable to have children (infertile).
The DelveInsight Prader-Willi Syndrome (PWS) market report gives a thorough understanding of the Prader-Willi Syndrome by including details such as disease definition, classification, symptoms, etiology, pathophysiology, diagnostic trends. It also provides treatment algorithms and treatment guidelines for Prader-Willi Syndrome in the US, Europe, and Japan.
Prader-Willi Syndrome Epidemiology
The Prader-Willi Syndrome (PWS) epidemiology division provide the insights about historical and current patient pool and forecasted trend for every 7 major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the DelveInsight report also provides the diagnosed and treatable patient pool and their trends along with assumptions undertaken.
The disease epidemiology covered in the report is segmented by diagnosed prevalent population, mutation-specific prevalent population and prevalent population of Prader-Willi Syndrome by clinical manifestations.
The DelveInsight report also provides the epidemiology trends observed in the 7MM during the study period, along with the assumptions undertaken. The calculated data are presented with relevant tables and graphs to give a clear view of the epidemiology at first sight.
According to DelveInsight, the prevalent population of Prader-Willi Syndrome was estimated to be 47,560 [7MM] in 2018. United States accounts for the highest Prader-Willi cases, followed by EU5 (Germany, France, Italy, Spain & UK) and Japan. Among the EU5 countries Germany had the highest prevalent patient population of Prader-Willi Syndrome, followed by Italy.
Prader-Willi Syndrome Drug Chapters
This segment of the Prader-Willi Syndrome report encloses the detailed analysis of marketed drugs and late stage (Phase-III) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.
At present, pharmacological management of Prader-Willi Syndrome focuses largely on the use of human growth hormone (HGH) supplementation which is approved in the US. Growth hormone supplementation constitutes the primary component of the entire therapeutic market composition due to the nearly ubiquitous deficiency of growth hormone (GH) in PWS patients. Some of the majorly approved GH therapies include Pfizer’s Genotropin (somatropin) along with other major brands such as Norditropin (Novo Nordisk) and a few others in the US. Central nervous system and cardiovascular agents are used with increasing frequency in older PWS patients. Another approved drug is Omnitrope (somatropin [rDNA origin] injection) from Sandoz. Detailed chapters for all of these drug therapies have been covered in the report.
Prader-Willi Syndrome Market Outlook
The Prader-Willi Syndrome (PWS) market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.
This segment gives a through detail of market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria’s, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the global market of Prader-Willi Syndrome (PWS) was estimated to be USD 2110.17 million in 2018. The United States accounts for the largest market size of Prader-Willi Syndrome, in comparison to EU5 (the United Kingdom, Germany, Italy, France, and Spain), and Japan. Amongst the therapeutic class, Hormone Therapies hold the highest patient share [%] amongst the other therapeutic options available for the treatment of PWS. The increasing awareness of the disease assisted by organizational support along with the promising pipeline therapies is expected to fuel the market size during the forecasted period of 2019-2028.
Prader-Willi Syndrome Drugs Uptake
This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2017-2028. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Upcoming therapies, such as DCCR (Soleno Therapeutics), LV-101 (Levo Therapeutics) and Lariglutide (Novo Nordisk), have the potential to create a positive shift in the PWS market size during the study period (2017-2028). Expected launch of potential therapies will lead to an increase in the market size of Prader-Willi Syndrome (PWS) in the coming years. DCCR (Soleno Therapeutics) is the going to be the first FDA approved therapy that is expected to be launched in all of the 7 Major Markets, during the forecast period [2018-2028].
Prader-Willi Syndrome Report Insights
• Patient Population
• Therapeutic Approaches
• Pipeline Analysis
• Market Size and Trends
• Market Opportunities
• Impact of upcoming Therapies
Prader-Willi Syndrome Report Key Strengths
• 10 Year Forecast
• 7MM Coverage
• Epidemiology Segmentation
• Drugs Uptake
• Highly Analyzed Market
• Key Cross Competition
Prader-Willi Syndrome Report Assessment
• Current Treatment Practices
• Unmet Needs
• Detailed Pipeline Product Profiles
• Market Attractiveness
• Market Drivers and Barriers
• This DelveInsight report will help to develop Business Strategies by understanding the trends shaping and driving the Prader-Willi Syndrome market.
• Organize sales and marketing efforts by identifying the best opportunities for Prader-Willi Syndrome market.
• To understand the future market competition in the Prader-Willi Syndrome market.
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