Antibodies in Oncology Drug Pipeline Update 2012Published by: BioSeeker Group AB Published: Oct. 16, 2012 Table of Contents
AbstractThe commercial and therapeutic success of antibodies like Rituxan, Avastin, and Erbitux will force the industry to look into the next generation of therapeutic antibodies, preparing themselves for the second wave in the lucrative field of therapeutic antibodies.There are today 300 companies plus partners developing 582 antibody drugs in 1358 developmental projects in cancer. In addition, there are 6 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 312 drugs. Antibodies In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 278 different targets. These targets are further categorized on in the software application by 53 classifications of molecular function and with pathway referrals to BioCarta, KEGG and NetPath. How May Drug Pipeline Update Be of Use?
Drug Pipeline Update is delivered to you as a downloadable application, which requires no installation on your computer. Please read more about application features and system requirements below. Drug Pipeline Update at a Glance Investigators Includes more than 300 principal investigators plus their collaborators. There is direct access from inside the application to web pages of all principal investigators. Note: You are able to sort and find drugs according to investigators and partners from drop-down menus in the application. You may also sort and find drugs according to country of investigator. Drug name & Synonyms Lists commercial, generic and code names for drugs. Developmental stage This Drug Pipeline Update contains 582 antibody drugs in development, which have a total of 1358 developmental projects in cancer. In addition there are suspended and ceased drugs. Pipeline Breakdown According to Number of Drugs Marketed# 18 Pre-registration# 1 Phase III# 37 Phase II# 128 Phase I# 168 Preclinical# 432 No Data# 1 Suspended# 6 Ceased# 312 Note: You are able to sort and find drugs according to developmental stage from drop-down menu in the application. Indications Included antibody drugs are also in development for 153 other indications, where of 82 are different cancer indications. Note: You are able to find and sort drugs according to type of indication from drop-down menu in the application. Targets Identified drugs are linked to more than 278 different targets, divided into 53 classifications of molecular function:
Note: You are able to find and sort drugs according to target gene name, molecular function of target, and target localization from drop-down menus in the application. Target Expression Profile Direct links are provided from inside the application to 349 protein expression profiles of 215 drug targets in various human tissues and cancer types, cell lines and primary cells, including up to:
Identified targets have been cross referenced against their involvement in different cellular pathways, according to BioCarta, KEGG and NetPath.
Note: You are able to find and sort drugs according to targeted pathways from drop-down menus in the application. Mechanism In total there are different drug mechanism of action represented in this Drug Pipeline Update. Note: You are able to find and sort drugs according to mechanism of action from drop-down menu in the application. Compound Identified drug compounds are described by: Compound type, Chemical name, CAS Number and molecular weight Note: You are able to sort and find drugs according to compound type from drop-down menu in the application. Drug Profile Progress analysis and review of drug development. A typical drug profile reports on, depending on stage of development and available information: Drug Name & Synonyms Presentation of drug name and synonyms Principal Investigator & Partners Presentation of principal investigator and partners Target and Molecular Function of Target Described target(s) is/are presented with: Official Gene Symbol – Official Gene Name [Species/Homo Sapiens] – Molecular Function Target Localization Described target(s) is/are presented with primary and alternate localizations. Target Expression Profiles Links to protein expression profile(s) of target(s) in various human tissues, cell lines and primary cells, including up to: 48 different normal tissue types 20 different types of cancer 47 cell lines 12 samples of primary blood cells Targeted Pathways Described target(s) is/are matched for the involvement in cellular pathways according to BioCarta, KEGG, and NetPath. Mechanism Drug mechanism of action Developmental Projects Summary field of developmental projects for the drug, including indication, developmental stage and status. Example: Cancer, myeloma – Phase II Clinical Trial – Active Cancer, prostate – Phase III Clinical Trial – Ceased Drug Description Short introduction to drug Compound Data Compound type, Chemical name, CAS Number and molecular weight Patent Data Available patent information related to the drug is presented here. Business & Markets Collaborations and deals Approvals and submissions Analyst comments Phase III Data Available Phase III development data, developmental history and scientific data. Phase II Data Available Phase II development data, developmental history and scientific data. Phase I Data Available Phase I development data, developmental history and scientific data. Preclinical Data Available preclinical development data, developmental history and scientific data. Licensing Information Availability for licensing Application Features Use 13 different parameters, available in drop-down menus, to find and sort among drugs
Our dynamic report generator lets you with ease and speed generate html reports directly in your web browser (Internet Explorer and FireFox), whether it is a single drug profile or an entire search you want have a report of. System Requirements
Get full details about this report >> |
|
|
|
About MarketResearch.com
|
||
|
|
On the WEB
1/18/2013 - 32