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Growth Factors (Blood And Tissue)

Published by: Global Industry Analysts

Published: Oct. 1, 2008 - 576 Pages


Table of Contents


I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability And Reporting Limitations

Disclaimers

Data Interpretation & Reporting Level

Quantitative Techniques & Analytics

Product Definitions And Scope Of Study

Blood Growth Factors

Erythropoietins

Colony Stimulating Factors

Interferons

Interleukins

Tissue Growth Factors

II. EXECUTIVE SUMMARY

1. Introduction

Growth Factors: A Preface

Growth Factors: Their Role and Related Applications

Growth Factors: Adding a New Dimension

Growth Factors: Classification Based on Activity

Recent Trends & Developments

Recombinant Human Erythropoietin: Gradually Gaining Dominance

2. Market Overview

Analysis by Region

US: The Single Largest Market

Growth Factors Market in Europe

Market for Growth Factors in Rest of World

Table 1: World Market for Growth Factors (2000-2010): Geographic Regions Ranked by CAGR -US, Europe, Japan, and Rest of World (includes corresponding Graph/Chart)

Analysis by Growth Factor Type

EPO - The Lead ‘Factor’

Leading EPO Drugs Worldwide

Market Comparison of Erythropoietin-Based Drugs in America and European Union:

Classification Based on Key Parameters

Patent Expiries of Major Biopharmaceutical Drugs

3. Market Dynamics

Dethroning the Leaders

Expiration of Patents Fuels Competition and Sales

India - At the Center Stage

Side Effects - Still a Concern

CDER- A Regulatory Review Authority for Growth Factors

4. Outlook

Innovative Delivery System Shows Potential for Accelerating Use of Growth

Factors

Cytokines- Vital Growth Propellers for the Future of New Drugs

Brain Derived Neurotrophic Factor (BDNF) Finds Increased Application

Age-Related Diseases - Their Influence on Effective Therapies

Copaxone Finds Novel Applications

Mimetic Growth Factors - Exhibiting Promising Potential

5. Industry Issues

Development of Cost Effective Methods - Need of the Hour

Influence of Neurotrophic Factors on Brain Cell Development

Combination of Interferons and Ribavirin Develops More Anemia Cases

6. Competitive Trends

RegeneRx Focuses on Wound Healing Market

DRL Introduces a Program to Propel its Biogenerics Business

7. Growth Factors - An Overview

Blood Growth Factors

Erythropoietins

Types of Erythropoietins

Epoetin

Darbepoetin

Aranesp®

Aranesp Vs Other EPOs

Recombinant Human EPO (rHuEPO)

Table 2: World Market for Erythropoietins (2000-2010): Geographic Regions Ranked by CAGR - Europe, US, Japan and Rest of World (includes corresponding Graph/Chart)

Colony Stimulating Factors

Granulocyte-Colony Stimulating Factor

Granulocyte Macrophage-Colony Stimulating Factor

Other Colony Stimulating Factors

Macrophage Colony Stimulating Factor (M-CSF)

Key Functions of M-CSF

Side-Effects of Colony-Stimulating Factors

Table 3: World Market for Colony Stimulating Factors (2000-2010): Geographic Regions Ranked by CAGR - Japan, Europe, US, and Rest of World (includes corresponding Graph/Chart)

Interferons

Types of Interferons

Interferon-gamma

1a and 1b: Two Key Biochemical Forms of Interferon-ß

PEG-Intron

Types of Interferons

Table 4: World Market for Interferons as Blood Growth Factors (2000-2010): Geographic Regions Ranked by CAGR - US, Europe, Japan, and Rest of World (includes corresponding Graph/Chart)

Interleukins

Types of Interleukins

Table 5: World Market for Interleukins as Blood Growth Factors (2000-2010): Geographic Regions Ranked by CAGR - Europe, Japan, US, and Rest of World (includes corresponding Graph/Chart)

Tissue Growth Factors

Wound Healing Growth Factors

Neurotrophic Growth Factors

Nerve Growth Factor

Vascular Endothelial Growth Factor (VEGF)

Fibroblast Growth Factor (FGF)

Insulin-Like Growth Factor-I (IGF-I)

Insulin-Like Growth Factor-II (IGF-II)

Tissue Growth Factors: Classification Based on Key Source and Principal

Activity

Platelet - Derived Growth Factors in Wound Healing

Thrombopoietin (TPO)

Table 6: World Market for Tissue Growth Factors (2000-2010): Geographic Regions Ranked by CAGR - US, Europe, Japan, and Rest of World (includes corresponding Graph/Chart)

Growth Factors: Their Mode of Action in Tissue Repair

Angiogenesis: Their Role in Wound Healing

Angiogenesis As an Alternative for Cardiac Stents

Applications of Growth Factors

Growth Factors: Application by Compound and Supplier

Growth Factors: Indicated Applications by Site/Course of Action

8. Research and Development Highlights

Maxygen Updates on Factor VII Program

Evaluation of Extended Dosing Schedule of PROCRIT®

PROCRIT® - A Better Option

Nerve Growth Factor Shows Promising Potential Against Diabetes

Cytokines and GM-CSF Found to be Closely Interlinked

GM-CSF Enhances Rate of Survival in Neonates

rG-CSF Well Tolerated in Pneumonia and Severe Sepsis Patients

rG-CSF- Their Influence on Preterm Infants with Sepsis

Serum Macrophage Colony Stimulating Growth Factors Associated with Thrombocyte and Monocyte

Src Pathway Inactivation in Kit Impairs Blood Cell Growth and Proliferation

Cole Eye Institute Offers TIMP-3 Mechanism for Preventing Abnormal Growth of Blood

Vessels

Effect of Brain Derived Neurotrophic Factor on Retinal Cells

Orcel™ Exhibits High Growth Factor for Wound Healing and Cardiovascular

Applications

Drug Combination of Macrophage Colony Stimulating Factor Shows Successful Tolerance

Levels

Neotrofin ™ Triggers Neurotrophic Factors

G-CSF Shows Capability for Promoting Neutrophil Production

Insulin-like Growth Factor-1 (IGF) Gene Transfer Accelerates Wound Healing

Process

Hepatocyte Growth Factors - Exhibiting Dual Role

Cortex Pharmaceuticals Ampakines® Promotes Expression of Neurotrophin

Granulocyte Colony Stimulating Factor Finds Application in Treating Neonates

Cerebrolysin Promotes Cognition

9. Breakthroughs - A Review

Novel Set of Human Cytokines Unveiled

IGFBP-3 and its Potential to Ward Off Gastric Cancer

Bone Morphogenic Proteins Show Potential for Musculoskeletal Regeneration

Growth Factors - Their Role in Preventing Heart Stroke

Growth Factor Proteins Shows Promising Results for Treating Cancer

Neurotrophic Growth Factor Primarily Responsible for Loss of Vision

Redox-Active Grape Seed Exhibits Favorable Properties for Dermal Wound

Healing

Role of Brain-Derived Neurotrophic Factor on Memory

Nerve Growth Factor Found to Enhance Barium Current and Insulin Secretion

Lipid Peroxidation May be Associated with Wound Healing

Genentech Inc Unveils Molecule for Stimulating Growth of Blood Vessels

Connective Tissue Growth Factor Found to Promote Lung Fibroblast

Influence of Insulin-Like Growth Factor on Growth

Regeneron Discovers Angiopoietins Targeted at Blood Vessel Growth and Repair

Environment and Insulin-Like Growth Factors Stimulate Risk of Cancer

Cocktail of Neurotrophic Factors Promotes Regeneration of Torn Nerves

Growth Factors Administration to Stimulate Tissue Repair

Cytokine - Their Role in Combating Hepatitis C Virus

Axokine® Yields Favorable Results Against Obesity

Cell Genesys Unveils GDNF Gene Therapy Targeted Against Parkinson’s Disease

10. Recent Industry Activity

Pfizer Inks Exclusive Global Licensing Agreement with Scil Technology

ZGEN Initiates Ph II Trial of Interleukin 21

FzioMed Bags Health Canada Approval on Oxiplex®

NsGene A/S Implants Encapsulated Cell in Patients

Reliance Life Sciences Takes Over Genemedix

Fraunhofer Institute Introduces First Interferon Beta 1a to Treat Multiple Sclerosis

Shanghai Wanxing Inks Export Deal for Recombinant Human Interferon

Hemispherx Enters into Distribution Agreement with Armada

Bayer Launches US Pharmaceuticals Subsidiary

Merck Inks Agreement with Bristol-Myers Squibb and ImClone

CoGenesys Signs Global Licensing Agreement with Vegenics

InterMune Inks New Supply Deal with Boehringer Ingelheim

Boston Life Sciences Adopts New Name of Alseres Pharmaceuticals

Cambrex Divests Bioproducts and Biopharma Subsidiaries

Dragon Divests EPO Business

Caregene and Genzyme Forms Partnership to Develop Cere-120

Amgen Bags EC Approval on Use of Aranesp(R) in Paediatric Patients

NsGene to Undertake Phase Ib Clinical Trial of NsG0202

Roche Receives European approval for NeoRecormon

Bolder Receives Two U.S. Patents for Hematopoietic Factors

Hospira Receives EC Approval on Retacrit

RLS to Initiate Clinical Trials of Erythropoietin

InterMune Drops Phase III trial of Interferon

Chugai to Conduct Additional Trial on Epogin®

Merck KGaA Acquires Serono Labs

CytoPharm Acquires Low-Dose Interferon License from Amarillo Biosciences

Hospira Signs Agreements with STADA and BIOCEUTICALS for Erythropoietin

Biocon Bags GEAC Approval to Conduct Clinical Trial of Granulocyte Colony Stimulating

Factor

SII to Conduct Clinical Trials of Rdna Products

Claris to Construct Production Facility for EOP

Mayne and Pliva to End Collaboration on Erythropoietin Development

GeneMedix Collaborates with CJ Corp

FzioMed and USC Enter into Licensing Agreement for Oligopeptides

Tercica Receives FDA Approval For Increlex

AnGes MG Enters Into An Agreement with Vical

Corautus and BIA Sign Agreement for VEGF-2 plasmid DNA

Dragon Pharmaceuticals Acquires Oriental Wave

Insmed Enters into Exclusive Agreement with UCSF for IGF-1 Series

Amrad and Ludwig Institute Jointly Focus on the Development of VEGF-B

GeneMedix Restructures Business

pSivida Limited Collaborates with Ian Wark Research Institute

Amgen Acquires Tularik

BMPI Signs up Luitpold Pharmaceuticals for FDA Approved GEM 21S™

DPI Receives Approvals for Erythropoietin in Three New Markets

Chugai and Roche Expand Drug Research Synergies

Dragon Pharmaceuticals to Construct New Production Facility

FibroGen Signs Contract with Yamanouchi for Licensing EPO Small Molecule

Insmed and Tzamal Pharma Sign Agreement for Promoting SomatoKine

Maxygen and Rentschler Enter into a Contract for G-CSF

Maxygen Signs Agreement with Biovitrum for Manufacturing Beta Interferon

Dragon Pharmaceuticals Signs Agreement with Zhongkai

Dragon Pharmaceuticals Enters into Definitive Agreement with Oriental Wave

Zymogenetics Bags US FDA Clearance

Ceregene Bags Patent

11. Strategic Corporate Developments in Recent Past

AME Enters into Third Collaboration with Eli Lilly and Company

ViaCell Enters into Licensing Agreement and Collaboration with Amgen

Ceregene Enters into Licensing Agreement with Genentech

BIOPHARM GmbH Enters into Licensing Contract with DePuy

Maxygen Enters into a Deal with Roche Holding

Dragon Pharmaceuticals Bags Market Approval from Chinese SDA

GeneMedix Signs Agreement with SkyePharma

Neurotech Enters into Licensing Agreement with Amgen

Ceregene Enters into a Licensing Agreement with Washington University

NeoTherapeutics Receives US Patent for Stimulating Neuritogenesis

BioSET Bags Global Exclusive License for Novel Growth Factor Technology

ViaCell Acquires Cerebrotec

Fibrogen Collaborates with Sankyo

Prescient NeuroPharma Collaborates with SRIB

Dragon Pharmaceuticals Signs Agreement with Renapharm AB and Transworld

Baxter Bags Exclusive Worldwide Rights for Epoetin Omega

Ortec International Bags FDA PMA for OrCel

GeneMedix Bags Chinese SDA Approval

NsGene Collaborates with ARIAD Pharmaceuticals

Regeneron Enters into Agreement with Emisphere Technologies

NsGene A/S Signs Agreement with Biogen Inc

NTB Enters into BioInformatics Outsourcing Agreement with HSC

12. Product Launches in Recent Past

Wockhardt Introduces Wepox Recombinant Erythropoietin Drug

Shanta Biotechnics Unveils Shanferon

SkinMedica Unveils TNS Recovery Complex™ Gel

CellGenix Unveils Cytokines for Cell Applications

Cel-Sci Corporation Develops Multikine

Wockhardt Limited Unveils EPOX™

13. Focus on Select Global Players

Amgen, Inc. (USA)

BioMimetic Therapeutics, Inc. (USA)

Biopharm GmbH (Germany)

Bolder Biotechnology, Inc. (USA)

Alseres Pharmaceuticals, Inc. (USA)

Ceregene Inc. (USA)

FibroGen Inc. (USA)

FzioMed Inc. (USA)

GeneMedix Plc. (UK)

Insmed Inc. (USA)

Johnson & Johnson (USA)

Janssen-Ortho Inc. (Canada)

Lonza Group (Switzerland)

Maxygen, Inc. (USA)

Merck Serono International S.A. (Switzerland)

NsGene A/S (Denmark)

PeproTech Inc. (USA)

Rentschler Biotechnologie GmbH (Germany)

F. Hoffmann-La Roche Ltd (Switzerland)

Chugai Pharmaceutical Co. Ltd. (Japan)

Genentech Inc. (USA)

Shantha Biotechnics (India)

Scil Proteins GmbH (Germany)

Wockhardt Ltd. (India)

14. Global Market Perspective

Table 7: World Recent Past, Current & Future Analysis for Growth Factors (Blood and Tissue) by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 8: World Long-term Projections for Growth Factors (Blood and Tissue) by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 9: World 10-Year Perspective for Growth Factors (Blood and Tissue) by Geographic Region - Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 10: World Recent Past, Current & Future Analysis for Blood Growth Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 11: World Recent Past, Current & Future Analysis for Blood Growth Factors by Type - Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 12: World Long-term Projections for Blood Growth Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 13: World Long-term Projections for Blood Growth Factors by Type - Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 14: World 10-Year Perspective for Blood Growth Factors by Geographic Region - Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 15: World 10-Year Perspective for Blood Growth Factors by Type - Percentage Breakdown of Value Sales for Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 16: World Recent Past, Current & Future Analysis for Erythropoietins by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 17: World Long-term Projections for Erythropoietins by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 18: World 10-Year Perspective for Erythropoietins by Geographic Region - Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 19: World Recent Past, Current & Future Analysis for Colony Stimulating Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 20: World Long-term Projections for Colony Stimulating Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 21: World 10-Year Perspective for Colony Stimulating Factors by Geographic Region - Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 22: World Recent Past, Current & Future Analysis for Interferons as Blood Growth Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 23: World Long-term Projections for Interferons as Blood Growth Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 24: World 10-Year Perspective for Interferons as Blood Growth Factors by Geographic Region - Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 25: World Recent Past, Current & Future Analysis for Interleukins as Blood Growth Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 26: World Long-term Projections for Interleukins as Blood Growth Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 27: World 10-Year Perspective for Interleukins as Blood Growth Factors by Geographic Region - Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

Table 28: World Recent Past, Current & Future Analysis for Tissue Growth Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 29: World Long-term Projections for Tissue Growth Factors by Geographic Region - US, Japan, Europe, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 30: World 10-Year Perspective for Tissue Growth Factors by Geographic Region - Percentage Breakdown of Value Sales for US, Japan, Europe, and Rest of World Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

III. MARKET

1. The United States

A. Market Analysis

Current and Future Analysis

EPO Market Scenario

Key Market Driver for EPO

Leading EPO Drugs in the US

Recent Industry Activity

Strategic Corporate Developments in Recent Past

Product Launches in Recent Past

Key Players

B. Market Analytics

Table 31: US Recent Past, Current & Future Analysis for Growth Factors by Type - Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 32: US Long-term Projections for Growth Factors by Type - Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 33: US 10-Year Perspective for Growth Factors by Type - Percentage Breakdown of Value Sales for Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

2. Japan

A. Market Analysis

and Future Analysis

Erythropoietin Market: Competitive Scenario

Leading EPO Drugs in Japan

Market Scenario for Biotech Products

Biotech Market Backed by Public Assistance

dustry Activity

Charmaceutical Co. Ltd. - A Key Player

B. Market Analytics

Table 34: Japanese Recent Past, Current & Future Analysis for Growth Factors by Type - Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 35: Japanese Long-term Projections for Growth Factors by Type - Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 36: Japanese 10-Year Perspective for Growth Factors by Type - Percentage Breakdown of Value Sales for Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

3. Europe

A. Market Analysis

Current and Future Analysis

Erythropoietin Market Scenario in the Recent Past

Leading EPO Drugs in Europe

Recent Industry Activity

Strategic Developments in Recent Past

Product Launch in Recent Past

Key Players

B. Market Analytics

Table 37: European Recent Past, Current & Future Analysis for Growth Factors by Type - Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 38: European Long-term Projections for Growth Factors by Type - Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 39: European 10-Year Perspective for Growth Factors by Type - Percentage Breakdown of Value Sales for Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

4. Rest of World

A. Market Analysis

Current and Future Analysis

An Overview of Indian Market

Erythropoiet III-30 G-CSF

Interferon

Recent Industry Activity

Strategic Developments in Recent Past

Product Launches in Recent Past

Key Players

B. Market Analytics

Table 40: Rest of World Recent Past, Current & Future Analysis for Growth Factors by Type - Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets Independently Analyzed with Annual Sales in US$ Million for Years 2000 through 2010 (includes corresponding Graph/Chart)

Table 41: Rest of World Long-term Projections for Growth Factors by Type - Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets Independently Analyzed with Annual Sales in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)

Table 42: Rest of World 10-Year Perspective for Growth Factors by Type - Percentage Breakdown of Value Sales for Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons and Interleukins) and Tissue Growth Factors Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 90 (including Divisions/Subsidiaries - 101)

Region/Country Players

The United States 55

Canada 3

Japan5

Europe 24

Germany 11

The United Kingdom2

Rest of Europe11

Asia-Pacific (Excluding Japan) 14


Abstract

This report analyzes the worldwide markets for Growth Factors (Blood And Tissue) in Millions of US$. The major product segments analyzed are Blood Growth Factors (Erythropoietins, Colony Stimulating Factors, Interferons, & Interleukins), and Tissue Growth Factors. The report provides separate comprehensive analytics for the US, Japan, Europe, and Rest of World. Annual forecasts are provided for each region for the period of 2000 through 2015. The report profiles 90 companies including many key and niche players worldwide such as Amgen, Inc., BioMimetic Therapeutics, Inc., Biopharm GmbH, Bolder Biotechnology, Inc., Alseres Pharmaceuticals, Inc., Ceregene Inc., FibroGen Inc., FzioMed Inc., FzioMed Inc., GeneMedix PLC, Insmed Inc., Johnson & Johnson, Janssen-Ortho, Inc., Lonza Group, Maxygen, Inc., Merck Serono International S.A., NsGene A/S, PeproTech, Inc., Rentschler Biotechnologie GmbH, F. Hoffmann-La Roche Ltd., Chugai Pharmaceutical Co. Ltd., Genentech, Inc., Shantha Biotechnics, Scil Proteins GmbH, and Wockhardt Ltd. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.

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