Market Research Logo

CNS Cluster Addiction Drug Development Pipeline Review, 2017

CNS Cluster Addiction Drug Development Pipeline Review, 2017

Summary

This report provides an overview of the CNS Clusters pipeline landscape. The report provides comprehensive information on the therapeutics under development, and key players involved in therapeutic development for Alcohol Addiction, Drug Addiction, Nicotine Addiction, Opium (Opioid) Addiction and features dormant and discontinued projects.

Alcohol addiction refers to a psychological and physical dependency on alcohol. Symptoms include decreased involvement in extracurricular activities, depression, restlessness, inability to control drinking and violent behavior. There are a total of 38 products in development for this indication, by 29 companies and five academic institutions. Key companies operating in this pipeline space include Abbvie, Astraea Therapeutics, Lochola Research and SK Biopharmaceuticals.

Drug addiction, also called substance dependence or chemical dependency, is a disease that is characterized by a destructive pattern of drug abuse that leads to significant problems involving tolerance to or withdrawal from the substance. There are a total of 67 products in development for this indication, by 38 companies and 16 academic institutions. Key companies operating in this pipeline space include Astraea Therapeutics, Addex therapeutics, The University of Kansas, Embera NeuroTherapeutics, InterveXion Therapeutics, Omeros, Opiant Pharmaceuticals and Orexigen Therapeutics.

Nicotine addiction also called tobacco dependence is an addiction to tobacco products caused by the drug nicotine. There are a total of 19 products in development for this indication, by 13 companies and 5 academic institutions. The majority of companies are developing single pipeline program in this space, while Omeros are developing two.

Finally, opioid addiction develops after using opioids regularly for a period of time. Prolonged use of opiates can lead to nerve damage within the brain that causes cells to stop producing endogenous opiates (natural painkillers known as endorphins). There are a total of 33 products in development for this indication, by 23 companies and three academic institutions. Key companies operating in this pipeline space include Indivior, INSYS Therapeutics, Omeros, Pfizer and Zynerba Pharmaceuticals.

There is a substantial degree of overlap between these indications in terms of the types of molecular target which are being studied. The mu and kappa-opioid receptors are the dominant molecular target across alcohol, drug and opioid addiction, and other neurotransmitter receptors such as the cannabinoid and dopamine receptors are common molecular targets across the three. In contrast, while such neurotransmitter receptors are present in the nicotine addiction pipeline, the opioid receptors are not, and the dominant molecular target is the orexin receptor type 1.

Scope

  • Which companies are the most active within the pipeline for addiction therapeutics?
  • Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
  • To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
  • What are the most important R&D milestones and data publications to have happened in the field of addiction therapeutics?
Reasons to buy
  • Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
  • Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication, and a comprehensive picture of recent updates and milestones for each
  • Analyze the companies, institutions and universities currently operating in the pipeline, and the products being fielded by each of these
  • Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration


Executive Summary
Introduction
CNS Cluster Addiction Report Coverage
Alcohol Addiction – Overview
Drug Addiction – Overview
Nicotine Addiction – Overview
Opium (Opioid) Addiction – Overview
Therapeutics Development
Alcohol Addiction
Drug Addiction
Nicotine Addiction
Opium (Opioid) Addiction
Therapeutics Assessment
Alcohol Addiction
Drug Addiction
Nicotine Addiction
Opium (Opioid) Addiction
Companies Involved in Therapeutics Development
Alcohol Addiction
Drug Addiction
Nicotine Addiction
Opium (Opioid) Addiction
Dormant Projects
Alcohol Addiction
Drug Addiction
Nicotine Addiction
Opium (Opioid) Addiction
Discontinued Products
Alcohol Addiction
Drug Addiction
Nicotine Addiction
Opium (Opioid) Addiction
Product Development Milestones
Alcohol Addiction
Drug Addiction
Nicotine Addiction
Opium (Opioid) Addiction
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Number of Products under Development for Alcohol Addiction
Number of Products under Development by Companies, Alcohol Addiction
Number of Products under Development by Universities/Institutes, Alcohol Addiction
Products under Development by Companies, Alcohol Addiction
Products under Development by Universities/Institutes, Alcohol Addiction
Number of Products under Development for Drug Addiction
Number of Products under Development by Companies, Drug Addiction
Number of Products under Development by Universities/Institutes, Drug Addiction
Products under Development by Companies, Drug Addiction
Products under Development by Universities/Institutes, Drug Addiction
Number of Products under Development for Nicotine Addiction
Number of Products under Development by Companies, Nicotine Addiction
Number of Products under Development by Universities/Institutes, Nicotine Addiction
Products under Development by Companies, Nicotine Addiction
Products under Development by Universities/Institutes, Nicotine Addiction
Number of Products under Development for Opium (Opioid) Addiction
Number of Products under Development by Companies, Opium (Opioid) Addiction
Number of Products under Development by Universities/Institutes, Opium (Opioid) Addiction
Products under Development by Companies, Opium (Opioid) Addiction
Products under Development by Universities/Institutes, Opium (Opioid) Addiction
Number of Products by Stage and Target, Alcohol Addiction
Number of Products by Stage and Mechanism of Action, Alcohol Addiction
Number of Products by Stage and Route of Administration, Alcohol Addiction
Number of Products by Stage and Molecule Type, Alcohol Addiction
Number of Products by Stage and Target, Drug Addiction
Number of Products by Stage and Mechanism of Action, Drug Addiction
Number of Products by Stage and Route of Administration, Drug Addiction
Number of Products by Stage and Molecule Type, Drug Addiction
Number of Products by Stage and Target, Nicotine Addiction
Number of Products by Stage and Mechanism of Action, Nicotine Addiction
Number of Products by Stage and Route of Administration, Nicotine Addiction
Number of Products by Stage and Molecule Type, Nicotine Addiction
Number of Products by Stage and Target, Opium (Opioid) Addiction
Number of Products by Stage and Mechanism of Action, Opium (Opioid) Addiction
Number of Products by Stage and Route of Administration, Opium (Opioid) Addiction
Number of Products by Stage and Molecule Type, Opium (Opioid) Addiction
Alcohol Addiction – Pipeline by AbbVie Inc
Alcohol Addiction – Pipeline by Addex Therapeutics Ltd
Alcohol Addiction – Pipeline by Adial Pharmaceuticals LLC
Alcohol Addiction – Pipeline by Astraea Therapeutics LLC
Alcohol Addiction – Pipeline by BioCorRx Inc
Alcohol Addiction – Pipeline by Bionex Pharmaceuticals LLC
Alcohol Addiction – Pipeline by Bioprojet SCR
Alcohol Addiction – Pipeline by Cerecor Inc
Alcohol Addiction – Pipeline by Chronos Therapeutics Ltd
Alcohol Addiction – Pipeline by Corcept Therapeutics Inc
Alcohol Addiction – Pipeline by Curemark LLC
Alcohol Addiction – Pipeline by Eli Lilly and Company
Alcohol Addiction – Pipeline by Ethypharm SA
Alcohol Addiction – Pipeline by Euthymics Bioscience Inc
Alcohol Addiction – Pipeline by H. Lundbeck A/S
Alcohol Addiction – Pipeline by Heptares Therapeutics Ltd
Alcohol Addiction – Pipeline by Indivior Plc
Alcohol Addiction – Pipeline by Kinnov Therapeutics SAS
Alcohol Addiction – Pipeline by Kyorin Pharmaceutical Co Ltd
Alcohol Addiction – Pipeline by Lohocla Research Corp
Alcohol Addiction – Pipeline by Omeros Corp
Alcohol Addiction – Pipeline by Pfizer Inc
Alcohol Addiction – Pipeline by Savant HWP Inc
Alcohol Addiction – Pipeline by SK Biopharmaceuticals Co Ltd
Alcohol Addiction – Pipeline by Tonix Pharmaceuticals Holding Corp
Alcohol Addiction – Pipeline by VM Discovery Inc
Alcohol Addiction – Pipeline by XenoPort Inc
Alcohol Addiction – Pipeline by Zynerba Pharmaceuticals Inc
Drug Addiction – Pipeline by Addex Therapeutics Ltd
Drug Addiction – Pipeline by Aelis Farma SAS
Drug Addiction – Pipeline by Aphios Corp
Drug Addiction – Pipeline by Astraea Therapeutics LLC
Drug Addiction – Pipeline by BioCorRx Inc
Drug Addiction – Pipeline by Cerecor Inc
Drug Addiction – Pipeline by Chiesi Farmaceutici SpA
Drug Addiction – Pipeline by Curemark LLC
Drug Addiction – Pipeline by Embera NeuroTherapeutics Inc
Drug Addiction – Pipeline by F. Hoffmann-La Roche Ltd
Drug Addiction – Pipeline by Foresee Pharmaceuticals LLC
Drug Addiction – Pipeline by Heptares Therapeutics Ltd
Drug Addiction – Pipeline by Immunovaccine Inc
Drug Addiction – Pipeline by Indivior Plc
Drug Addiction – Pipeline by InterveXion Therapeutics LLC
Drug Addiction – Pipeline by Intra-Cellular Therapies Inc
Drug Addiction – Pipeline by Kyorin Pharmaceutical Co Ltd
Drug Addiction – Pipeline by Kyowa Hakko Kirin Co Ltd
Drug Addiction – Pipeline by MedRev Pharma
Drug Addiction – Pipeline by NLS Pharma Group
Drug Addiction – Pipeline by Omeros Corp
Drug Addiction – Pipeline by Opiant Pharmaceuticals Inc
Drug Addiction – Pipeline by Orexigen Therapeutics Inc
Drug Addiction – Pipeline by P2D Bioscience
Drug Addiction – Pipeline by Saniona AB
Drug Addiction – Pipeline by Savant HWP Inc
Drug Addiction – Pipeline by Stada Arzneimittel AG
Drug Addiction – Pipeline by Teva Pharmaceutical Industries Ltd
Drug Addiction – Pipeline by Zynerba Pharmaceuticals Inc
Nicotine Addiction – Pipeline by Addex Therapeutics Ltd
Nicotine Addiction – Pipeline by Astraea Therapeutics LLC
Nicotine Addiction – Pipeline by C4X Discovery Holdings PLC
Nicotine Addiction – Pipeline by Chronos Therapeutics Ltd
Nicotine Addiction – Pipeline by CV Sciences Inc
Nicotine Addiction – Pipeline by Hager Biosciences LLC
Nicotine Addiction – Pipeline by Heptares Therapeutics Ltd
Nicotine Addiction – Pipeline by Omeros Corp
Nicotine Addiction – Pipeline by Savant HWP Inc
Opium (Opioid) Addiction – Pipeline by Alkermes Plc
Opium (Opioid) Addiction – Pipeline by Aoxing Pharmaceutical Company Inc
Opium (Opioid) Addiction – Pipeline by Aquilus Pharmaceuticals Inc
Opium (Opioid) Addiction – Pipeline by BioCorRx Inc
Opium (Opioid) Addiction – Pipeline by BioDelivery Sciences International Inc
Opium (Opioid) Addiction – Pipeline by Camurus AB
Opium (Opioid) Addiction – Pipeline by Foresee Pharmaceuticals LLC
Opium (Opioid) Addiction – Pipeline by Heron Therapeutics Inc
Opium (Opioid) Addiction – Pipeline by Indivior Plc
Opium (Opioid) Addiction – Pipeline by INSYS Therapeutics Inc
Opium (Opioid) Addiction – Pipeline by Omeros Corp
Opium (Opioid) Addiction – Pipeline by Opiant Pharmaceuticals Inc
Opium (Opioid) Addiction – Pipeline by Orexigen Therapeutics Inc
Opium (Opioid) Addiction – Pipeline by Orexo AB
Opium (Opioid) Addiction – Pipeline by Pfizer Inc
Opium (Opioid) Addiction – Pipeline by Relmada Therapeutics Inc
Opium (Opioid) Addiction – Pipeline by Savant HWP Inc
Opium (Opioid) Addiction – Pipeline by Teva Pharmaceutical Industries Ltd
Opium (Opioid) Addiction – Pipeline by Titan Pharmaceuticals Inc
Opium (Opioid) Addiction – Pipeline by Zynerba Pharmaceuticals Inc
Alcohol Addiction – Dormant Projects
Drug Addiction – Dormant Projects
Nicotine Addiction – Dormant Projects
Opium (Opioid) Addiction – Dormant Projects
Alcohol Addiction – Discontinued Products
Drug Addiction – Discontinued Products
Nicotine Addiction – Discontinued Products
Opium (Opioid) Addiction – Discontinued Products
List of Figures
Number of Products under Development for Alcohol Addiction
Number of Products under Development by Companies, Alcohol Addiction
Number of Products under Development by Universities/Institutes, Alcohol Addiction
Number of Products under Development for Drug Addiction
Number of Products under Development by Companies, Drug Addiction
Number of Products under Development by Universities/Institutes, Drug Addiction
Number of Products under Development for Nicotine Addiction
Number of Products under Development by Companies, Nicotine Addiction
Number of Products under Development for Opium (Opioid) Addiction
Number of Products under Development by Companies, Opium (Opioid) Addiction
Number of Products under Development by Universities/Institutes, Opium (Opioid) Addiction
Number of Products by Top 10 Targets, Alcohol Addiction
Number of Products by Stage and Top 10 Targets, Alcohol Addiction
Number of Products by Top 10 Mechanism of Actions, Alcohol Addiction
Number of Products by Stage and Top 10 Mechanism of Actions, Alcohol Addiction
Number of Products by Routes of Administration, Alcohol Addiction
Number of Products by Stage and Routes of Administration, Alcohol Addiction
Number of Products by Molecule Types, Alcohol Addiction
Number of Products by Stage and Molecule Types, Alcohol Addiction
Number of Products by Top 10 Targets, Drug Addiction
Number of Products by Stage and Top 10 Targets, Drug Addiction
Number of Products by Top 10 Mechanism of Actions, Drug Addiction
Number of Products by Stage and Top 10 Mechanism of Actions, Drug Addiction
Number of Products by Routes of Administration, Drug Addiction
Number of Products by Stage and Routes of Administration, Drug Addiction
Number of Products by Molecule Types, Drug Addiction
Number of Products by Stage and Molecule Types, Drug Addiction
Number of Products by Top 10 Targets, Nicotine Addiction
Number of Products by Stage and Top 10 Targets, Nicotine Addiction
Number of Products by Top 10 Mechanism of Actions, Nicotine Addiction
Number of Products by Stage and Top 10 Mechanism of Actions, Nicotine Addiction
Number of Products by Stage and Routes of Administration, Nicotine Addiction
Number of Products by Molecule Types, Nicotine Addiction
Number of Products by Stage and Molecule Types, Nicotine Addiction
Number of Products by Top 10 Targets, Opium (Opioid) Addiction
Number of Products by Stage and Top 10 Targets, Opium (Opioid) Addiction
Number of Products by Top 10 Mechanism of Actions, Opium (Opioid) Addiction
Number of Products by Stage and Top 10 Mechanism of Actions, Opium (Opioid) Addiction
Number of Products by Routes of Administration, Opium (Opioid) Addiction
Number of Products by Stage and Routes of Administration, Opium (Opioid) Addiction
Number of Products by Molecule Types, Opium (Opioid) Addiction
Number of Products by Stage and Molecule Types, Opium (Opioid) Addiction

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook

Share this report