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The Future of Nutrigenomics: New opportunities in personalized nutrition and food-pharma collaboration

Published by: Business Insights

Published: Jan. 1, 2010 - 151 Pages


Table of Contents


The Future of Nutrigenomics
Executive summary
Defining nutrigenomics
Market drivers
Collaborative nutrigenomic research & consortia
Leading food & drinks companies: nutrigenomic strategies
Leading nutrigenomic testing companies
Opportunities: convergence of pharma & diagnostics
Challenges: regulation, ethical & IP issues
Conclusions
Chapter 1 Defining nutrigenomics
Summary
Introduction
‘Omic technologies
Nutrigenomics and the food & drinks industry
Nutrigenomics & food products
Nutrigenomics & personalized nutrition
Report outline
Chapter 2 Market drivers
Summary
Introduction
Drivers for personalized nutrition
Healthy aging
Consumer demographics
Chronic non-communicable disease
Urbanization and the emerging markets
Global health economics
Conclusions on drivers for personalized nutrition
Chapter 3 Collaborative nutrigenomic research & consortia
Summary
Introduction
Nutrigenomic research consortia
Nutrigenomic research in the EU
The European Nutrigenomics Organization (NuGO)
DiOGenes
TI Food and Nutrition
Vision EpiFood Project
Canada Foundation for Innovation (CFI)
Public-private in age-related diseases
Nutrigenomic research in the US
Public-private partnership: genetically modified crops
Nutrigenomic research across the world
International Society of Nutrigenetics/Nutrigenomics (ISNN)
Conclusions
Chapter 4 Leading food & drinks companies: nutrigenomic strategies
Summary
Introduction
Ingredients manufacturers approach to nutrigenomics
BASF
Chr Hansen
DSM
Food manufacturers’ approach to nutrigenomics
Group Danone
Nestlé
Unilever
Pharma industry M&A in consumer nutrition
The evolving open network model
Co-development opportunities
Areas for market growth & time scales
Conclusions
Chapter 5 Leading nutrigenomic testing companies
Summary
Introduction
Market leaders
23andme.com
GeneLink
Gene Smart
Genova Diagnostics
Interleukin Genetics Inc
WellGen Inc.
Conclusions
Chapter 6 Opportunities: convergence of pharma & diagnostics
Summary
Introduction
Nutrigenomics vs pharmacogenomics
Global health issues treatment vs prevention
Convergence of the pharmaceutical & diagnostic market
Conclusions
Chapter 7 Challenges: regulation, ethical & IP issues
Summary
Introduction
Regulation of nutrigenomic foods
Europe
Japan
Regulation of nutrigenomic tests
Ethical issues
Public awareness & perceptions
Intellectual Property
Conclusions
Chapter 8 Conclusions
Summary
The food & drinks market
Global genetic testing market
Market trends
Overall conclusions
Appendix
Primary research methodology
Acknowledgments
Glossary
Index
Bibliography
Endnotes
List of Figures
Figure 1.1: Nutrigenetics and nutrigenomics
Figure 1.2: The ‘omics technologies
Figure 1.3: The functional genomic tool box
Figure 1.4: Applications of nutrigenomics in the food chain
Figure 2.5: Drivers for the food & drinks industry
Figure 2.6: The ageing population a driver for personalized nutrition
Figure 2.7: Personalized nutrition targeting consumer segments
Figure 2.8: Population over 60: world and developed regions (1950-2050)
Figure 2.9: Nutritional challenges - obesity & metabolic syndrome
Figure 2.10: Growth in consumers in developing & emerging countries (2008-2018)
Figure 2.11: Healthcare expenditure as a share of GDP (2006)
Figure 2.12: Target population of nutrigenomic based products
Figure 4.13: BASF approach to gene discovery
Figure 4.14: DSMs sales growth targeting four emerging business areas
Figure 4.15 DSMs R&D competencies
Figure 4.16 An International and interdisciplinary network
Figure 4.17 Diversify & de-risk through externalization
Figure 4.18 Open network model
Figure 4.19: Waves of nutrigenomic development
Figure 5.20: WellGen’s nutrigenomic based discovery
Figure 6.21: Nutrigenomics vs pharmacogenomics
Figure 6.22: Relationship of drugs, disease, genes and gene products
Figure 8.23: Health and nutrition market segments (2009)
Figure 8.24: Nutrigenomic impact on personalized nutrition
List of Tables
Table 3.1: European Consortia and Nutrigenomic Research Programs
Table 3.2: Nutrigenomics Network Programs
Table 4.3: Stakeholders in nutrigenomic research and personalized nutrition
Table 4.4: Chr Hansen - strategic alliances & investments
Table 4.5: Nestlé nutrigenomic alliances & investments
Table 4.6: Divestment of Animal, Consumer & Medical Nutrition Divisions
Table 4.7: Consumer Health Divisions of Pharmaceutical Companies
Table 4.8: Alliance between Food, Pharma, Biotech and the Diagnostic Industries
Table 5.9: Categorization of genetic variations that may be included in nutrigenomic tests
Table 5.10: Categorization of genetic variations that may be included in nutrigenomic tests
Table 6.11: Known diet- gene interactions
Table 6.12: Known gene-nutrient interactions

Abstract

Nutrigenomics explores how nutrients or bioactive dietary compounds can influence gene expression and an individuals risk to certain diseases. Nutrigenetics is the study of how variations in an individual’s genetic makeup can increase or decrease the need for a specific nutrient or bioactive food component.

Nutrigenomics has the potential to impact various parts of the food chain including the genetic modification of crops and animal feeds, the development of nutrigenomic tests to monitor food safety and personalization of diets, as well as the identification of nutritional supplements and nutrigenomic based products which may offer potential health benefits. The consumer environment is driving growth in the Nutrition & Health market.

Over the past decade, consumers have become more concerned for their health and are increasingly inclined to invest in DTC nutrigenetic tests to assess their risk of disease and obtain dietary advice. Healthcare providers too, are keen to shift some of the burden of healthcare costs to individuals and recognize that the personalization of nutrition may be beneficial. The Health and nutrition market is currently worth around $485 billion.

This report reviews the business strategies of leading companies regarding the adoption of nutrigenomic technologies and establishment of public-private partnerships as well as potential opportunities for biomarker discovery with the pharma and diagnostic industry to personalize nutrition and medicine.

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