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US Bio-Detection Homeland Security & Defense Technology & Market Forecast - 2010-2014

Published by: Homeland Security Research Corporation

Published: Feb. 1, 2009 - 222 Pages


Table of Contents


1 Scope

1.1 Definition of Biological Terrorism

1.2 Scope

1.2.1 Bio Weapon Types

1.3 Basic Assumptions

1.3.1 General

1.3.2 Why Conduct Constant Surveillance for Biological Warfare Threats?

1.3.3 Possible Scenario Analysis

1.4 Methodology

1.4.1 Research Methods

1.4.2 Report Structure

1.5 Who is This Report For?

2 Executive Summary

2.1 Main Conclusions

2.2 The Threat of Bioterrorism

2.3 How Real Is The Bioterrorism Threat?

2.4 Defending Against Bioterrorism

2.4.1 Project BioWatch

2.4.2 Project BioSense

2.4.3 Project BioShield

2.5 Bio-Detection - The Industry

2.6 Bio-Detection Market Forecast - 2010-2014

2.6.1 Total Bio-Detection Systems and Service Market Forecast - 2010-2014

2.6.2 Bio-Detection Systems & Service Market Forecast by Modality - 2010-2014

2.6.3 Bio-Detection Market Forecast by Technology Generation - 2010-2014

2.7 Bio-Detection - Next Generation Business Opportunities

2.8 Bio-Detection - Technologies Outlook

3 Bio-Detection Market - Drivers

4 Bio-Detection Market - Inhibitors

5 The Obama Administration Bio Terror Mitigation Strategy

5.1 Bio-Defense Funding

5.1.1 DHHS Bio-Defense Missions and Funding

5.1.2 DHS Bio-Defense Missions and Funding

5.1.3 DOD Bio-Defense Missions and Funding

5.1.4 DOA Bio-Defense Missions and Funding

5.1.5 EPA Bio-Defense Missions and Funding

5.1.6 Other Bio-Defense Missions and Funding

5.2 The Obama Administration Bio-Defense Strategy

6 Bio-Detection - Technologies Overview

6.1 Bio-Detection Technology Challenges

6.1.1 Sampling the Environment

6.2 The Bio-Detection Process

6.2.1 Bio-Detectors in a Multitude of Ambient Settings

6.2.2 Bio-Detection Triggering

6.2.3 Collection of Particles

6.2.4 Bio-Particle Detectors

6.2.5 Bio-Agent Identification

7 Bio-Detection Technological Challenges
7.1 Challenge 1 - Detection of Small Particle Concentration

7.2 Challenge 2 - Eliminating Bio Background

7.3 Challenge 3 - Expensive Reagents

7.4 Challenge 4 - Expensive Equipment Maintenance

7.5 Challenge 5 - Adapting Equipment to Changing Environments

7.6 Challenge 6 - Dealing With Emerging Threats

8 Bio Detection Technologies Review & Outlook - 2010-2014

8.1 Bio-Detection - Core Technologies Comparison

8.2 Collector/Concentrator Core Technologies

8.3 Cyclone Collectors

8.4 Variable Particle-Size Impactor

8.5 Virtual Impactors

8.6 Impingers

8.7 Reagentless Trigger Core Technologies

8.7.1 Flow Cytometry

8.7.2 Particle Sizing

8.7.3 Gas Chromatography

8.7.4 Trigger Technologies - Drivers

8.7.5 Trigger Technologies - Inhibitors

8.8 DNA Based Diagnostic Core Technologies

8.8.1 Overview of DNA-Based Detection

8.8.2 Polymerase Chain Reaction (PCR)

8.8.3 DNA / RNA Microarrays

8.8.4 DNA Technology Drivers

8.8.5 DNA Technology Inhibitors

8.9 Antibody-Antigen Diagnostic Core Technologies

8.9.1 Overview of Antibody-Antigen Reaction

8.9.2 Hand-Held Immuno-Chromatographic Assays (HHA)

8.9.3 Magnetic Microbead-Base Assays

8.9.4 Microfluidic Devices - “Lab on a Chip”

8.9.5 Fluorescence Imaging

8.9.6 Electrochemical-Luminescence (ECL)

8.9.7 Antibody/Antigen Technology - Drivers

8.9.8 Antibody/Antigen Technology - Inhibitors

8.10 Signal Analysis Algorithms

8.10.1 Clustering / Classifier Algorithms

8.10.2 Image Analysis Algorithms

8.10.3 Decision Algorithms

8.10.4 Algorithm Drivers

8.10.5 Algorithm Inhibitors

8.11 Rapid Microbiological Technologies

9 Biological Detection - Overview by Application

9.1.1 Application 1 - Emergency Responder Hand-Held Detectors

9.1.2 Application 2 - Emergency Responder Mobile Labs

9.1.3 Application 3 - Indoor Standoff Detectors

9.1.4 Application 4 - Outdoor Standoff Detectors

10 U.S. Bio-Detection Systems Market Outlook - 2010-2014

10.1 Scope, Assumptions and Overview

10.1.1 Scope

10.2 Bio-Detection Systems Revenue Sales Forecast - 2010-2014

10.2.1 Bio-Detection Systems Revenue Sales by Generation Forecast - 2010-2014

10.2.2 Bio-Detection Systems Sales by Modality Forecast - 2010-2014

10.3 Bio-Detection Systems Quantity Sales Forecast - 2010-2014

10.3.1 Bio-Detection Systems Quantity Sales by Generation Forecast - 2010-2014

10.3.2 Bio-Detection Systems Quantity Sales by Modality Forecast - 2010-2014

10.4 Bio-Detection Systems Installed Base Forecast - 2010-2014

10.4.1 Bio-Detection Systems Installed Base by Generation Forecast - 2010-2014

10.4.2 Bio-Detection Systems Installed Base by Modality Forecast - 2010-2014

10.5 Bio-Detection Outdoor Standoff-Detection Systems - Market Forecast - 2010-2014

10.5.1 Outdoor Standoff Detection Systems Revenue Sales Outlook - 2010-2014

10.5.2 Outdoor Standoff Detection Systems Quantity Sales Outlook - 2010-2014

10.5.3 Outdoor Standoff Detection Systems Installed Base Outlook - 2010-2014

10.6 Bio-Detection Indoor Systems Standoff-Detection Market Forecast - 2010-2014

10.6.1 Indoor Standoff Systems Detection Sales Outlook - 2010-2014

10.6.2 Indoor Standoff Detection Systems Unit Sales Outlook - 2010-2014

10.6.3 Indoor Standoff Detection Systems Installed Base - 2010-2014

10.7 Bio-Detection - Point-Detection (Detect-to-Treat) Systems - Installed Base Forecast - 2010-2014

10.7.1 Point-Detection Summary Overview

10.8 Bio-Detection First Responder Hand-Held Detection Systems Market Forecast - 2010-2014

10.8.1 First Responder Hand-Held Detection Systems Sales Outlook - 2010-2014

10.8.2 First Responder Hand-Held Detection Systems Quantity Sales Outlook - 2010-2014

10.8.3 First Responder Hand-Held Detection Systems Installed Base - 2010-2014

10.9 Bio-Detection First Responder Mobile Labs Detection Systems Market Forecast - 2010-2014

10.9.1 First Responder Mobile Labs Sales Outlook - 2010-2014

10.9.2 First Responder Mobile Labs Quantity Sales Outlook - 2010-2014

10.9.3 First Responder Mobile Labs Installed Base - 2010-2014

11 Bio-Detection Service Business Outlook - 2010-2014

11.1 Bio-Detection Service & Upgrade Business Forecast by Modality - 2010-2014

11.2 Bio-Detection Service Business Forecast by Technology Generation - 2010-2014

12 Bio-Detection Business Opportunities - 2010-2014

12.1 Historical Perspective: A Market Waiting for Transition

12.1.1 The Current and Future HLS Bio-Defense Strategy for Detection

12.1.2 Factors Affecting Biological Detectors Deployment and Technologies - 2010-2014

12.1.3 Biological Detection Technology Timeline - 1992-2014

12.2 Business Opportunities for Next Generation HLS Bio-Detection Systems

12.2.1 Business Opportunity 1 - Emerging Threats

12.2.2 Business Opportunity 2 - Human Sentinel Surveillance System

12.2.3 Business Opportunity 3 - Animal Sentinel Surveillance System

12.2.4 Business Opportunity 4 - Biological IC3 - Biological Threat Assessment Intelligence Command, Control, and Communication Infrastructure

12.2.5 Business Opportunity 5 - Reducing False Alarms - Lesser False Positives and False Negatives

12.2.6 Business Opportunity 6 - Reducing Cost - Minimizing Use of Non-Reusable Reagents

12.3 Outdoor Standoff Biological Detectors

12.3.1 Business Opportunity 7 - Bioagent Autonomous Networked Detectors (BAND)

12.3.2 Business Opportunity 8 - Rapid Automated Biological Identification System (RABIS)

12.3.3 Business Opportunity 9 - First Responder Portable Hand-Held Detector

12.3.4 Business Opportunity 10 - First Responder Mobile Biological Detection Station

12.3.5 Business Opportunity 11 - Regional Automatic Detector - Outdoor Standoff Detectors

12.3.6 Business Opportunity 12 - Networked Automatic Detector - Indoor Standoff Detectors

12.3.7 Business Opportunity 13 - External Spread of Bioagent Detection

12.3.8 Business Opportunity 14 - Internal Spread of Bioagent

12.4 Other Bio-Detection Technologies - Business Opportunities

12.4.1 Business Opportunity 15 - “Lab on a Chip” - Miniature Detection Devices

12.4.2 Business Opportunity 16 - Reagentless Specific Detection Assays

12.4.3 Business Opportunity 17 - Laser Induced Breakdown Spectroscopy (LIBS)

12.4.4 Business Opportunity 18 - Raman Spectroscopy-based Reagentless Detection

12.5 Future Technologies and Systems

13 Bio-Defense Federal R&D Funding Opportunities - 2010-2014

13.1 Summary & Outlook

13.2 Bio-Defense Federal R&D Funding Forecast - 2010-2014

13.2.1 DHS Biosecurity R&D

13.2.2 DOD Bio-Security R&D

13.2.3 DHHS Biosecurity R&D

13.2.4 Other Agencies Biosecurity R&D

13.3 HLS-HLD Bio-Detection R&D Funding - Drivers

13.4 HLS-HLD Bio-Detection R&D Funding Opportunities - Inhibitors

13.5 DHS - Biological Detection HLS Technologies R&D Programs

13.5.1 Surveillance and Detection R&D

13.5.2 Rapid Development for Sensors for Novel Threat Agents

13.5.3 Cross Correlation of Environmental Biological Sensors and Human Illness

13.5.4 Facility Airborne Biological Toxin Alarm System (FABTAS)

13.5.5 Field-Deployable Detection Technology for the Identification of Biological Toxins

13.5.6 Forensics

13.6 DARPA (DOD) - Biological Detection HLS Technologies R&D Programs

13.6.1 Handheld Isothermal Silver Standard Sensor (HISSS)

13.6.2 Triangulation Identification for Genetic Evaluation of Biological Risk (TIGER)

13.6.3 Spectral Sensing of Bio-Aerosols (SSBA)

13.6.4 Threat Agent Cloud Tactical Intercept Countermeasure (TACTIC)

13.6.5 Immune Buildings

13.7 CBDP (DOD) - Biological Detection HLS Technologies R&D Programs

13.7.1 Project CB1 - Biological Defense (Basic Research) - Detection

13.7.2 Project CB2 - Biological Defense (Applied Research) - Detection

13.7.3 Project CB3 - Biological Defense (ATD) - Detection

13.7.4 Project CA5 Contamination Avoidance (SDD)

13.8 TSWG - Biological Detection HLS Technologies R&D Programs

13.8.1 Real-Time Biological Aerosol Detection

14 Bio-Detection Pricing Outlook - 2010-2014

15 Bio-Detection - Economic Considerations

15.1 Overview

15.2 Economical Analysis - Assumptions

15.2.1 Bio-Detection - Economic Analysis

15.2.2 Cost of Equipment Ownership

15.2.3 Cost of Personnel/Year

15.2.4 Cost of Test

16 Bio-Detection - Personnel Considerations

16.1 Background - Personnel

16.2 Personnel Training

17 Bio-Detection - Vendors and Products

17.1 Bio Detection Samplers and Products

17.2 Bio Detection Kits - Vendors and Products

17.3 Bio Detection Screening Devices - Vendors and Products

18 Appendix A: The Threat of Bioterror

18.1 Use of Bioweapons - Historical Perspective

18.2 Biological Terror - Bacterial Agents

18.2.1 Anthrax

18.2.2 Cholera

18.2.3 Plague

18.2.4 Tularemia

18.3 Biological Terror - Viral Agents

18.3.1 Smallpox

18.3.2 Hemorrhagic Fever Viruses

18.3.3 Venezuelan Equine Encephalitis

18.4 Biological Terror - Rickettsiae Agents

18.4.1 Q Fever

18.4.2 Typhus

18.5 Biological Terror - Toxins

18.5.1 Botulinum Toxin

18.5.2 Ricin

18.5.3 Saxitoxin

18.5.4 Staphylococcal Enterotoxin B (SEB)

19 Appendix B: Bio-Detection - Patent Review

19.1 Scope

19.2 Bio-Detection Patents

20 Appendix C: Legal Issues

20.1 International / European Legislation / Agreements

20.1.1 The Biological and Toxin Weapons Convention (BTWC) 1972

20.2 U.S. Bioterrorism Legislation

List of Tables

2 Executive Summary

Table 1 - HLS & Defense Bio-Detection Systems and Service Market [$M] 2008 & 2014 - by Product Classification

Table 2 - Federal HLS-HLD Bio-Defense Funding [$Million] - FY2001-FY2009

Table 3 - U.S. HLS Bio-Detection Systems and Service Market Forecast [$ Million] - 2010-2014

Table 4 - U.S. HLS Bio-Detection Systems & Service (S&S) Market Forecast by Expenditure Share [%] - 2010-2014

Table 5 - U.S. HLS Bio-Detection Systems & Service Market Forecast by Portability [$ Million] - 2010-2014

Table 6 - U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality Share [%] - 2010-2014

Table 7 - Bio-Detection Systems Sales by Generation [$ Million] - 2010-2014

Table 8 - Bio-Detection Systems Sales by Generation [%] - 2010-2014

Table 9 - Bio-Detection Service and Upgrade Business Forecast by Technology Generation [$ Million] - 2010-2014

Table 10 - Bio-Detection Service and Upgrade Business Forecast by Technology Generation Share [%] - 2008-2014

5 The Obama Administration Bio Terror Mitigation Strategy

Table 11 - U.S. Federal HLS-HLD Bio-Defense Funding [$ Millions], by Agency - FY2001-FY2009

8 Bio Detection Technologies Review & Outlook - 2010-2014

Table 12 - Comparison of Attributes of Bio-Detection Technologies

10 U.S. Bio-Detection Systems Market Outlook - 2010-2014

Table 13 - Bio-Detection Systems Sales by Generation [$ Million] - 2010-2014

Table 14 - Bio-Detection Systems Sales by Generation Share [%] - 2010-2014

Table 15 - Bio-Detection Consolidated Sales by Modality [$M] - 2010-2014

Table 16 - Bio-Detection Systems Sales by Modality Share [%] - 2010-2014

Table 17 - Bio-Detection Systems Quantity Sales by Generation [Units] - 2010-2014

Table 18 - Bio-Detection Systems Quantity Sales by Generation Share [%] - 2010-2014

Table 19 - Bio-Detection Systems Quantity Sales by Modality [Units] - 2010-2014

Table 20 - Bio-Detection Systems Quantity Sales by Modality Share [%] - 2010-2014

Table 21 - Bio-Detection Systems Installed Base by Generation [Units] - 2010-2014

Table 22 - Bio-Detection Systems Installed Base Share [%] by Generation - 2010-2014

Table 23 - Bio-Detection Systems Installed Base by Modality [Units] - 2010-2014

Table 24 - Bio-Detection Systems Installed Base by Modality Share [%] - 2010-2014

Table 25 - Outdoor Standoff Detectors Systems Sales by Generation [$ Million] - 2010-2014

Table 26 - Outdoor Standoff Detectors Systems Sales by Generation Share [%] - 2010-2014

Table 27 - Outdoor Standoff Detectors Systems Sales [Units] - 2010-2014

Table 28 - Outdoor Standoff Detectors Systems Sales Share [%] - 2010-2014

Table 29 - Outdoor Standoff-Detectors Systems Installed Base [Units] - 2010-2014

Table 30 - Outdoor Standoff-Detectors Systems Installed Base Units Share [%] - 2010-2014

Table 31 - Indoor Standoff Detectors Systems Sales by Generation [$M] - 2010-2014

Table 32 - Indoor Standoff Detectors Systems Sales by Generation Share [%] - 2010-2014

Table 33 - Indoor Standoff Detectors Systems Sales by Generation [Units] - 2010-2014 CAGR

Table 34 - Indoor Standoff Detectors Systems Sales by Generation Share [%] - 2010-2014

Table 35 - Indoor Standoff-Detectors Systems Installed Base by Generation [Units] - 2010-2014

Table 36 - Indoor Standoff-Detectors Systems Installed Base by Generation Share [%] - 2010-2014

Table 37 - Point-Detectors Installed Base Systems by Modality [Thousand of Units] - 2010-2014

Table 38 - First Responder Hand-Held Detection Systems Sales [$M] by Generation - 2010-2014

Table 39 - First Responder Hand-Held Detection Systems Sales by Generation Share [%] - 2010-2014

Table 40 - First Responder Hand-Held Detection Systems Sales [Units] by Generation - 2010-2014

Table 41 - First Responder Hand-Held Detection Systems Sales by Generation Share [%] - 2010-2014

Table 42 - First Responder Hand-Held Detection Systems Installed Base by Generation [Units] - 2010-2014

Table 43 - First Responder Hand-Held Detection Systems Installed Base by Generation Share [%] - 2010-2014

Table 44 - First Responder Mobile Labs Sales by Generation [$M] - 2010-2014

Table 45 - First Responder Mobile Labs Sales by Generation Share [%] - 2010-2014

Table 46 - First Responder Mobile Labs Sales by Generation [Units] - 2010-2014

Table 47 - First Responder Mobile Labs Unit Sales by Generation Share [%] - 2010-2014

Table 48 - First Responder Mobile Labs Installed Base by Generation [Units] - 2010-2014

Table 49 - First Responder Mobile Labs Units Installed Base by Generation Share [%] - 2010-2014

11 Bio-Detection Service Business Outlook - 2010-2014

Table 50 - Bio-Detection Service & Upgrade Business Forecast by Modality [$M] - 2010-2014

Table 51 - Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] - 2010-2014

Table 52 - Bio-Detection - Service Business Forecast by Technology Generation [$M] - 2010-2014

Table 53 - Bio-Detection Service Business Forecast by Technology Generation Share [%] - 2010-2014

13 Bio-Defense Federal R&D Funding Opportunities - 2010-2014

Table 54 - Bio-Defense R&D Federal Funding by Agency [$ Million] - 2010-2014

17 Bio-Detection - Vendors and Products

Table 55 - Bio Detection Samplers - Vendors and Products

Table 56 - Bio Detection Kits - Vendors and Products

Table 57 - Bio-Detection Screening Devices - Vendors and Products

List of Figures

1 Scope

Figure 1 - Types of Biological Detectors

2 Executive Summary

Figure 2 - HLS & Defense Bio-Detection Systems and Service Market [$M] 2008 & 2014 - by Product Classification

Figure 3 - Bio-Detection Strategy - Three Pillars Diagram

Figure 4 - U.S. Government HLS-HLD Bio-Defense Funding [$ Million] - FY2001-FY2009

Figure 5 - U.S. HLS Bio-Detection Systems & Service Market Forecast [$ Million] - 2010-2014

Figure 6 - U.S. HLS Bio-Detection Systems & Service Market Share [%] - 2008, 2011 & 2014

Figure 7 - U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality [$ Million] - 2010-2014

Figure 8 - U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality Share [%] - 2008, 2011 & 2014

Figure 9 - Bio-Detection Systems Sales by Generation [$ Million] - 2010-2014

Figure 10 - Bio-Detection Service Business Forecast by Technology Generation [$ Million] - 2010-2014

5 The Obama Administration Bio Terror Mitigation Strategy

Figure 11 - Cumulative 2001-2009 Bio-Defense Funding [$Million], by Agency

Figure 12 - Bio-Defense Funding Share [%], by Agency - 2001, 2004 & 2009

6 Bio-Detection - Technologies Overview

Figure 13 - Comparison in Weight of Pathogens Between BW Agents and CW Agents [mg]

Figure 14 - Typical Point Detection Automated Architecture (With a Combined Trigger/Cue)

Figure 15 - Airborne Bacterial Concentration Fluctuation in a Single Day

Figure 16 - Cross-Section of Cascade Impactor: PIXE International Corporation

Figure 17 - TSI's Model 3317 System with Concentrator, GPS Receiver & Wireless Data Radio

8 Bio Detection Technologies Review & Outlook - 2010-2014

Figure 18 - Biological Detection Technologies - 2010-2014

Figure 19 - Flow Cytometry

Figure 20 - Gas Chromatography

Figure 21 - Polymerase Chain Reaction

Figure 22 - RT-PCR

Figure 23 - Principles of Real-Time PCR

Figure 24 - DNA Microarrays - Principles of Operation

Figure 25 - Schematic for Antibody Protein

9 Biological Detection - Overview by Application

Figure 26 - Hand Held Detectors: Alexeter Guardian Reader System and Tetracore Test Strips

Figure 27 - Roche Applied Science - Light CyclerTM Model 1.2

10 U.S. Bio-Detection Systems Market Outlook - 2010-2014

Figure 28 - Bio-Detection Systems Sales by Generation [$M] - 2010-2014

Figure 29 - Bio-Detection Systems Sales by Generation Share [%] - 2008, 2011 & 2014

Figure 30 - Bio-Detection Systems Sales by Modality [$M] - 2010-2014

Figure 31 - Bio-Detection Systems Sales by Modality Share [%] - 2008, 2011 & 2014

Figure 32 - Bio-Detection Systems Quantity Sales by Generation [Units] - 2010-2014

Figure 33 - Bio-Detection Systems Quantity Sales by Generation Share [%] - 2008, 2011 & 2014

Figure 34 - Bio-Detection Systems Quantity Sales by Modality [Units] - 2010-2014

Figure 35 - Bio-Detection Systems Quantity Sales by Modality Share [%] - 2008, 2011 & 2014

Figure 36 - Bio-Detection Systems Installed Base by Generation [Units] - 2010-2014

Figure 37 - Bio-Detection Systems Installed Base Share [%] by Generation - 2008, 2011 & 2014

Figure 38 - Bio-Detection Systems Installed Base by Modality [Units] - 2008-2014

Figure 39 - Bio-Detection Systems Installed Base by Modality Share [%] - 2008, 20011 & 2014

Figure 40 - Outdoor Systems Standoff Detectors Sales by Generation [$M] - 2010-2014

Figure 41 - Outdoor Standoff Detectors Systems Sales by Generation Share [%] - 2008, 2011 & 2014

Figure 42 - Outdoor Standoff Detectors Systems Sales [Thousand of Units] - 2010-2014

Figure 43 - Outdoor Standoff Detectors Systems - Sales Share [%] - 2008, 2011 & 2014

Figure 44 - Outdoor Standoff-Detectors Systems Installed Base Units Share [Units] - 2010-2014

Figure 45 - Outdoor Standoff Detectors Systems Installed Base Share [%] - 2008, 2011 & 2014

Figure 46 - Indoor Standoff Detectors Systems Sales by Generation [$M] - 2010-2014

Figure 47 - Indoor Standoff Detectors Systems Sales by Generation Share [%] - 2008, 2011 & 2014

Figure 48 - Indoor Standoff Detectors Systems Unit Sales by Generation [Units] - 2010-2014

Figure 49 - Indoor Standoff Detectors Systems Sales by Generation Share [%] - 2008, 2011 & 2014

Figure 50 - Indoor Standoff-Detectors Systems Installed Base by Generation [Units] - 2010-2014

Figure 51 - Indoor Standoff Detectors Systems Installed Bases by Generation Share [%] - 2008, 2011 & 2014

Figure 52 - Point-Detectors Installed Base Systems Share by Modality [%] - 2008, 2011 & 2014

Figure 53 - First Responder Hand-Held Detection Systems Sales [$M] by Generation - 2010-2014

Figure 54 - First Responder Hand-Held Detection Systems Sales by Generation Share [%] - 2008, 2011 & 2014

Figure 55 - First Responder Hand-Held Detection Systems Sales by Generation [Units] - 2010-2014

Figure 56 - First Responder Hand-Held Detection Systems Sales by Generation Share [%] - 2008, 2011 & 2014

Figure 57 - First Responder Hand-Held Detection Systems Installed Base by Generation [Units] - 2010-2014

Figure 58 - First Responder Hand-Held Detection Systems Installed Base by Generation Share [%] - 2008, 2011 & 2014

Figure 59 - First Responder Mobile Labs Sales by Generation [$M] - 2010-2014

Figure 60 - First Responder Mobile Labs Sales by Generation Share [%] - 2008, 2011 & 2014

Figure 61 - First Responder Mobile Labs Sales by Generation [Units] - 2010-2014

Figure 62 - First Responder Mobile Labs Unit Sales by Generation Share [%] - 2008, 2011 & 2014

Figure 63 - First Responder Mobile Labs Unit Installed Base by Generation Share [Units] - 2010-2014

Figure 64 - First Responder Mobile Labs Installed Base by Generation Share [%] - 2008, 2011 & 2014

11 Bio-Detection Service Business Outlook - 2010-2014

Figure 65 - Bio-Detection Service & Upgrade Business Forecast by Modality [$M] - 2010-2014

Figure 66 - Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] - 2008, 2011 & 2014

Figure 67 - Bio-Detection Service & Upgrade Business Forecast by Technology Generation [$M] - 2010-2014

Figure 68 - Bio-Detection Service & Upgrade Business Forecast by Technology Generation [%] - 2008, 2011 & 2014

12 Bio-Detection Business Opportunities - 2010-2014

Figure 69 - Factors Affecting Biological Detection Deployment and Technologies - 2010-2014

Figure 70 - Bio-Detection Timeline

Figure 71 - Civilians in China During the SARS Epidemic

Figure 72 - A Typical Microfluidic Device

13 Bio-Defense Federal R&D Funding Opportunities - 2010-2014

Figure 73 - Bio-Defense R&D Federal Funding by Agency [$ Million] - 2010-2014

Figure 74 - DHS Bio-Security R&D Budget Forecast [$ Million] - 2010-2014 (Without Bio-Shield Funding)

Figure 75 - DOD Biosecurity R&D Budget Forecast [$ Million] - 2010-2014 (Without BioShield Funding)

Figure 76 - DHHS Bio-security R&D Budget Forecast [$ Million] - 2010-2014

Figure 77 - Other Agencies Biosecurity R&D Budget Forecast [$ Million] - 2010-2014

18 Appendix A: The Threat of Bioterror

Figure 78 - The Spraying of Anthrax from Aum Shinrikyo’s Headquarters June 1993

Figure 79 - Anthrax Spores and Disease

Figure 80 - Cholera Bacteria

Figure 81 - Pneumonic Plague - The Disease

Figure 82 - Tularemia - The Disease

Figure 83 - Smallpox Virus And Disease

Figure 84 - Ebola Virus - Electron Microscopy Image

Figure 85 - VEE - Venezuelan Equine Encephalitis Virus in the Olfactory Mucosa of a Mouse

Figure 86 - Q Fever

Figure 87 - Typhus Microbe - Electron Microscopy Image

Figure 88 - Castor Plant And Structure For The Ricin Toxin

Figure 89 - The Dinoflagellate Alexandrium Tamarense And Structure of Saxitoxin

Abstract

The Bio-Detection markets present some of the fastest growing and vibrant markets in the Homeland Security industry. The Obama administration is committed to accelerate the spending in Bioterror mitigation programs. In February 2009 the Congress passed a bill including additional funding of over $1.7 Billion, earmarked at Bio-security and Bio-health, and R&D.

This report describes the technologies and markets dedicated to using biological detectors for either constant automatic standoff surveillance of an indoor facility (e.g., mall, postal distribution center), an outdoor environment, or manual usage by 1st responders to check whether or not suspect traces consist of bio-terror agents. Such systems, in the context of Homeland Security, are mainly designed to mitigate the effects of biological terrorism.

HSRC’s team of scientists and industry executives meticulously researched and analyzed each of the 4 modalities of bio-detection:
  • Outdoor Automatic Standoff-Detectors (e.g., project BioWatch)
  • Indoor Automatic Standoff-Detectors
  • Emergency Responder Biological Mobile Labs
  • Emergency Responder Biological Hand-Held Detectors
For each modality, the research provides a detailed analysis and forecast for 3 generations of technologies, providing for 12 the market segments that will make up this industry for the next 5 years. For each of the modalities, the research provides the following:
  • Present & Next Generation Technologies - present technologies analysis and an in depth analysis of Bio-Detection candidates of next generation technologies
  • Current and upcoming business opportunities -18 specific business opportunities outlined and analyzed
  • 2010-2014 Market forecasts- Various and detailed forecasts of annual sales in units and dollars, for the next 5 years
  • 2010-2014 Service and upgrade business - 5 year forecasts of the service and equipment installation and upgrade business, which are the main source of gross margin for this industry


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