Tissue Engineering: Technology, Trends, and Market Opportunities

Published by: Drug and Market Development Publishing

Published: Sep. 1, 2004 - 120 Pages

Table of Contents

• Scope of Report
  
• Objectives
  
• Format
  
• Sources of Information
  
• Forecasts
  
• Definitions
  
• Exhibits

Chapter 3: Tissue Engineering: Progress and Promises

• Lessons Learned
  
• Going Forward

Chapter 4: Critical Components

• Cell Source
  
• Types of Cellular Material
  
• The Promise of Stem Cells
  
• Embryonic Stem Cells
  
• Adult Stem Cells
  
• Regulatory and Safety Issues
  
• Biomaterials, Matrices, and Scaffolds
  
• Importance of ECM
  
• Types of Materials
  
• Future Trends
  
• Use of Growth Factors
  
• Exploiting Self-Assembly
  
• Combinatorial Material Arrays
  
• Safety and Regulatory Issues
  
• Architecture
  
• Promoting Vascularization
  
• Manufacturing
  
• Three-dimensional Cell Culture
  
• Scale-up

Chapter 5: Applications

• Structural Tissue Engineering
  
• Skin
  
• Bone
  
• Cartilage
  
• Connective Tissue
  
• Muscle (non-cardiac)
  
• Organ Tissue Engineering
  
• Pancreas
  
• Liver
  
• Neural
  
• Cardiovascular

Chapter 6: Market Dynamics

• The Healthcare Environment
  
• Cost Containment
  
• Aging Population
  
• Pharmaceutical R&D Costs Rising
  
• Regulatory
  
• Specific Regulations for Tissue Engineered Products
  
• General Device Regulation
  
• Drug/Biological Product Approval
  
• Market Dynamics
  
• Burn and Wound Healing
  
• Demand Factors
  
• Barriers to Entry
  
• Commercialization Issues
  
• Competition
  
• Market Size
  
• Bone, Cartilage and Connective Tissue
  
• Demand Factors
  
• Barriers to Entry
  
• Commercialization Issues
  
• Competition
  
• Market Size
  
• Organ Repair and Replacement
  
• Demand Factors
  
• Barriers to Entry
  
• Commercialization Issues
  
• Competition
  
• Market Size

Chapter 7: Company Profiles

• 3DM, Inc.
  
• Acorda Therapeutics
  
• Advanced Cell Technology
  
• BioTissue Technologie GmbH
  
• Dentigenix, Inc.
  
• FibroGen
  
• Genzyme Biosurgery
  
• Geron Corporation
  
• Intercytex Limited
  
• Integra LifeSciences Holding Corporation
  
• Isotis OrthoBiologics
  
• Islet Sheet Medical LLC
  
• LifeCell Corporation
  
• NeuColl, Inc
  
• Novocell, Inc
  
• Ortec International, Inc
  
• Osiris Therapeutics, Inc
  
• OsteoBiologics, Inc
  
• Osteotech, Inc.
  
• ReGen Biologics, Inc.
  
• Selective Genetics, Inc.
  
• Smith & Nephew
  
• StemCells, Inc.
  
• TEI Biosciences, Inc
  
• Tepha, Inc

TABLE OF EXHIBITS

• Exhibit 1.1 Market for Tissue Engineered Products, 2002-2008 (thousands)
  
• Exhibit 4.1 Types of Stem Cells
  
• Exhibit 4.2 Human Embryonic Stem Cell Registry Companies with Available Cell Lines
  
• Exhibit 4.3 Collagen Types, Location and Characteristics
  
• Exhibit 4.4 Properties of Glycoaminoglycans
  
• Exhibit 4.5 Peptide Analogs to ECM Molecules
  
• Exhibit 4.6 Representative Biomaterials Used In Tissue Engineering
  
• Exhibit 4.7 Conventional Methods of Producing Scaffolds
  
• Exhibit 4.8 Angiogenesis Process
  
• Exhibit 4.9 Bioreactors Used in Tissue Engineering
  
• Exhibit 6.1 US Healthcare Spending—2002
  
• Exhibit 6.2 Percentage of Population Age 65 and Older, 2000-2020
  
• Exhibit 6.3 R&D Spending and New Product Approvals
  
• Exhibit 6.4 US Pharmaceutical R&D Spending By Application Area (2002)
  
• Exhibit 6.5 World Pharmaceutical Spending By Country (2001)
  
• Exhibit 6.6 Burns and Skin Ulcers—US, 2002
  
• Exhibit 6.7 Market for Tissue Engineered Burn and Wound Healing Products
  
• Exhibit 6.8 Bone, Cartilage, and Connective Tissue Procedures
  
• Exhibit 6.9 Market for Tissue Engineered Bone, Cartilage and Connective Tissue
  
• Repair Products (thousands)
  
• Exhibit 6.10 Number of Patients Waiting for Organ Transplants, US—2002
  
• Exhibit 6.11 Number of Organ Transplants, US—2002
  
• Exhibit 6.12 Average Yearly Expenses for Spinal Cord Injury Patient (In 2000 Dollars)
  
• Exhibit 6.13 Market of Tissue Engineered Organ Repair and Replacement Products

Abstract

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