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Food Allergies: New Treatments Are Nothing To Sneeze At

Published by: Datamonitor

Published: Aug. 18, 2003 - 31 Pages


Table of Contents


TABLE OF CONTENTS

ABOUT DATAMONITOR HEALTHCARE 2

About the Immune Disorders and Inflammation pharmaceutical analysis team 2

Executive Summary 6

Introduction 6

Scope and coverage of the Brief 6

Key findings about food allergies 7

Although increased media attention seems to point to the fact that the prevalence of food allergy is increasing, it will be difficult to quantify these statements until more accurate diagnostic methods have emerged, some of which are set to reach the market in the next two to four years. 7

Currently available treatment methods for food allergy are aimed at easing an allergic reaction once it has begun, however, new research in the area of immunotherapy (i.e. TNX-901 and Xolair), traditional Chinese medicine, and genetically engineered vaccines have the potential to dramatically alter management of food allergy in the near future. 8

While new treatment and diagnostic techniques are awaiting approval, manufacturers of marketed products can increase penetration in the near term through targeting areas of high unmet need such as the institution of national guidelines for adrenaline use, education of food allergy sufferers and their families and stronger enforcement of food labeling laws. 9

Food Allergies 11

Introduction 11

Prevalence and incidence of food allergies 12

Pathogenesis 12

Epidemiology 13

Diagnosis 15

Evaluation of current diagnostic methods 15

Controversial diagnostic techniques 17

Current Treatments 18

Antihistamines 18

Anti-inflammatory agents 18

Immunotherapy 19

Epinephrine 19

Non-pharmacological treatments 20

Current management guidelines for treating anaphylaxis 20

Promising treatments in early and late stage research 21

Traditional Chinese medicine/herbal therapies to prevent food allergy 21

Use of activated charcoal as an adjunct treatment for anaphylaxis 22

Novel immunotherapeutic strategies - TNX-901 and Xolair 23

Development of Detection Methods for Allergenic Foods 24

Rodent Model testing potential for future treatment 25

Vaccine therapy 25

Unmet needs 26

National guidelines 27

Inadequate specialists services for allergy care 27

Education of both children with food allergies and their families 27

Better diagnostics 28

Stricter enforcement of food labeling laws 28

Bibliography 30

Websites: 30

Articles: 31





Abstract

Introduction
Attempts to resolve the growing fears related to food allergies are increasing and the research efforts related to treating this condition have been gaining momentum in recent years. This trend is expected to continue in the future. As new research and treatments emerge, the potential for increased profits in this under-treated area will increase dramatically.

Scope
* Evaluation of current diagnostics and treatment paradigms in the management of food allergies, most notably peanut, seafood and milk allergies

* Overview of the incidence and prevalence of food allergies in the major markets

* Comparative analysis of the main growth areas of food allergy management in the future

* Identification of areas of highest unmet need in diagnosis, management and treatment of food allergies both now and in the future

Report Highlights
Although the media often states that the prevalence of food allergy is increasing, it will be difficult to quantify these statements until more accurate diagnostic methods have emerged, some of which are set to reach the market in the next two to four years.

New research in the area of immunotherapy (i.e. TNX-901 and Xolair), traditional Chinese medicine, and genetically engineered vaccines have the potential to dramatically alter management of food allergy in the near future.

Reasons to Purchase
* Assess the size of the current food allergy patient population and learn which segments will grow in the future

* Identify unmet needs in food allergies, from diagnosis to treatment, for more focused research

* Gain awareness of the latest research developments that will affect the food allergy market in both the near and distant future



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