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Medical and Biological Sensors and Sensor Systems: Markets, Applications, and Competitors Worldwide

Published by: Kalorama Information

Published: Sep. 1, 2002 - 313 Pages

Special Offer. Now 25% off the original price of $3500.

Table of Contents


Chapter One: Executive Summary


Chapter Two: Introduction To Sensors And Biosensors


    Basic Concepts

    • Definitions and Categories
    • Terminology


    Integrated and Smart Sensors


    Biomedical Applications


    Sensor Manufacturing Technologies


    • Monolithic Semiconductor Technologies
    • Ceramic-Based Sensors
    • Processing of Polymer Films
    • Optical-fiber Technologies


    General Biosensor Technology


Chapter Three: Biocompatibility And Standards For Medical Sensors


    Biocompatibility Considerations

    • Strategies for Reducing Blood coagulation on Sensor Surfaces
    • Applying New Cellular Process Research


    Sterilization Process for Medical Sensors


    Testing and Approval Standards for Medical Sensors


    The Review and Approval Processes


    • Step by Step
    • Nonclinical Testing
    • Clinical Testing
    • Biocompatibility of Medical Materials
    • The Standards Organizations
    • Types of Standards
    • Who Uses Standards?
    • The ASTM System


Chapter Four: Glucose Sensors


    Designing for Home Use

    • Friendly and Portable Equipment
    • Smaller Packages
    • Example of a Sensor for the New Medical Market


    Glucose Monitoring Equipment: Market Characteristics

    • Market Size and Growth


    Diabetes Monitoring Technologies

    • Dual Sensors: Earlier Warning for Diabetics
    • Implantable Electrochemical Glucose Sensors
    • Hypoglycemia Alarm
    • New Glucose Monitors, More Information
    • Three Sensor Strategies
    • Implanting a Sensor
    • Further Work Needed
    • Moving Implantables to Market
    • Implanted Sensor Stability


    Smart Insulin Pumps: An Artificial Pancreas


Chapter Five: Selected Medical Sensor Technologies


    Sensor Classification and Packaging


    Surgical Applications for Sensors


    Sensors for Diagnosis and Monitoring


    Important Design and Performance Considerations


    • Nontechnical Issues Can Be Critical
    • Precision and Accuracy
    • Cost of Ownership
    • Sample Collection and Handling
    • Performance Characteristics
    • System Size
    • Time per Test
    • Versatility
    • Sensitivity and Specificity
    • Manufacturing Technologies
    • Cost-Effectiveness


    Electrochemical Considerations

    • The Power Source
    • The Pacemaker Battery
    • Even Higher Currents Needed
    • Advanced Materials: A Must for Biosensor Development
    • Fuel Cell Power Sources
    • Sensors Based on Ion Selective Electrodes (ISE)
    • Distinguishing Between Medical Sensors and Biosensors


    Planar Electrochemical Biosensors

    • Requirements for Planar Sensor Systems
    • Precision and Accuracy of the System
    • Use- and Shelf Life
    • Ease of Use
    • Regulatory Requirements
    • Connectivity


Chapter Six: Market Dynamics


    The Medical Sensor Market

    • Antibody and Protein Sensors
    • Growth in the Market


    Non-Medical Biosensor Markets

    • Environmental Analysis
    • Water Analysis
    • Air and Gas Analysis
    • Explosives and Narcotics Detectors


    Ancillary Markets and Future Directions

    • Miniaturization, Automation, and Robotics
    • Intelligent Sensing: Micro Noses; Eyes and Ears
    • Medical Diagnostics
    • Drug Delivery Systems Tied to Medical Sensing


Chapter Seven: Current Research


    Medical Sensor Technology Based on DNA

    • New Biosensors
    • Hybrid DNA Biosensors
    • Hepatitis C Sensor
    • Ruthenium-Based Redox System
    • Molecular Bioelectronics Research Trends


    Medical Sensor Technologies Based on Optical Detection

    • Critters on a Chip
    • Bioluminescent Chips
    • Surface Plasmon Resonance Sensors
    • Infrared Device for Breast Cancer Testing
    • Other Space Technology
    • Oxygen Sensors Based on Luminescence Quenching


    Medical Sensing Technology for Imaging

    • Charge-coupled Devices (CCDs)
    • Bioengineering and Imaging Merge at NIH
    • The Capsule Endoscope


    Miscellaneous Sensor Developments

    • Biosensor Tool Kit
    • Imprinted Gels
    • Diagnostic Tests Using CD Players


Chapter Eight: Detection Of Living Organisms And Potential Threats


    The Challenge


    Overview of Biological Warfare Defense


    Detection of Chemical and Biological Weapons


    • Portable System Detection Developed at University of Delaware
    • Evaluating Symptoms Correctly
    • Genetic Analysis of Pathogens
    • Breath Testing
    • Biological Warfare Canaries
    • Accelerating Detection
    • The Search for a Small Portable Sensor for Airborne Toxins, Viruses, or Microbes
    • A Double-Edged Sword
    • Science and Deterrence
    • New Sensor Will Detect Chemical and Biological Pathogens at Incredibly Small Doses
    • Radio Controlled Aircraft


    Food Safety

    • Lab on a Chip
    • Microchip Bacteria Sensor
    • Tracking Foodborne Bacterium


    Water Safety

    • Security concerns
    • Productivity and Efficiency
    • Regulatory Forces


Chapter Nine: Biosensor And Medical Sensor Companies

  • Abaxis, Inc.
  • ACLARA BioSciences, Inc.
  • Advanced Biosensor, Inc.
  • Affymetrix, Inc.
  • Alaris Medical, Inc.
  • APL Group International LLC
  • Apollo Research Corp.
  • Arrhythmia Research Technology, Inc.
  • Avantes
  • Biacore International AB
  • BICO, Inc.
  • Biofield Corp.
  • Bio-logic Systems Corp.
  • Careside, Inc.
  • Cholestech Corporation
  • City Technology Ltd.
  • Cognex Corporation
  • Criticare Systems, Inc.
  • DecisionLink, Inc.
  • Diametrics Medical, Inc.
  • EP MedSystems, Inc.
  • Erich Jaeger GmbH
  • FISO Technologies Fiber Optic Sensors Inc.
  • Gamma Biologicals, Inc.
  • GE Medical Systems
  • GEFRAN S.p.A.
  • Genelabs Technologies, Inc.
  • Hemagen Diagnostics, Inc.
  • HL Planartechnik GmbH
  • Hoffrichter GmbH
  • Hologic, Inc.
  • Illumina, Inc.
  • Incyte Genomics, Inc.
  • Integrated Photonic Technology (IPITEK)
  • International Sensor Technology
  • Introtek International
  • Invivo Corporation
  • i-STAT Corporation
  • LifeChart.com, Inc.
  • Lifestream Technologies, Inc.
  • Masimo Corporation
  • Medtronic MiniMed
  • Minco Products
  • Novametrix Medical Systems Inc.
  • Novitron International, Inc.
  • O.I. Corporation
  • Oesch Sensor Technology
  • Omron Corporation
  • Optical Sensors Incorporated
  • Physiometrix, Inc.
  • PolyMedica Corporation
  • PVL Ltd.
  • Provalis plc
  • Quest Diagnostics Inc.
  • Respironics, Inc.
  • Select Engineering Inc.
  • Sensor Scientific Inc.
  • Sentronic GmbH
  • Spacelabs Medical, Inc.
  • SpectRx, Inc.
  • TECHNE Corporation
  • TheraSense, Inc.
  • TT electronics PLC
  • Utah Medical Products, Inc.
  • Zevex Inc.


Chapter Ten: Medical Sensors And Biosensors: Analyst’s Projections


    Sensitivity and Selectivity


    A Dreamer’s Biosensor of the Future


    Is their Another “Killer Application” Biosensor?


    The Future of Medical Sensor Technology


    • Medical Sensor Applications
    • Physical Sensors
    • Chemical and Biosensors


    Commercialization of Sensors


    Wireless Sensors


    • Wireless Sensors
    • Communications and Computers


    Medical Treatment


    Associated Technologies


    • Fiber-Optics Applications
    • Infrared Local Area Networks
    • On-Chip, Discrete RF Microelectromechanical Systems (RF-MEMS)


    Nanotechnology


Appendix: Recent Biosensor Patents








List of Exhibits

    Table 2-1: The Average Time for the Beginning of Blood Coagulation on
    Various Materials
    Table 2-2: Examples of Class I, II, and III Devices

    Table 2-3: Selected Representative ASTM Standard Test Methods for Polymers

    Table 2-4: Selected Typical ASTM Materials Standards

    Table 2-5: Selected Representative AAMI and ASTM Device Standards

    Table 2-6: Some Representative AAMI and ASTM Procedure Standards

    Table 4-1: Market for Blood Glucose Monitoring Equipment and Supplies in the
    Seven Major World Healthcare Markets, 1999-2007

    Table 6-1: World Biosensor Market by Application, 2001 and 2005

    Figure 4-1: Trending in the World’s Major Blood Glucose Monitoring
    Markets, 1999-2007

    Figure 4-2: Distribution of the Blood Glucose Monitoring Markets by Country

    Figure 6-1: Distribution of Biosensor Revenues by Application, 2001 and 2005


Abstract

The commercial world of medical sensors is vibrant and evolving rapidly. Reports that are only a year or two old are already out-of-date as new technologies make rapid penetration. The market is vast, so the stakes are high for those in the business or thinking about entering.

This new study from Kalorama attacks the field from the point of view of current R&D, technology and innovation, with an eye to potential markets and emerging technologies. The market for biosensor systems extends far beyond traditional medical monitoring and diagnostics, and this new report looks at the entire range of applications, including remote and military biosensor applications, process and materials quality control, environmental monitoring, and food and drug quality control.

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