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Published by: Global Industry Analysts
Published: Oct. 1, 2011 - 187 Pages
Table of Contents- 1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
- Study Reliability and Reporting Limitations
- Disclaimers
- Data Interpretation & Reporting Level
- Quantitative Techniques & Analytics
- Product Definitions and Scope of Study
- Cosmetic Applications
- Therapeutic Applications
- 2. INDUSTRY OVERVIEW
- A Prelude
- Current and Future Scenario
- By Geographic Region
- By Application
- Botulinum Toxin: “The Science, The Hopes & the Risks”
- Future Opportunities Span Beyond The Developed Markets
- 3. TRENDS & ISSUES
- Acceptance for Cosmetic BTX Treatment Grows
- Aging Population: A Weighty Demographic Driver
- Unmet Medical Needs Encourage Off-Label Use: A Cause for Concern or Jubilation?
- Urgent Need for Physician Education about Off Label Usage
- High Voltage Ad Campaigns Boost Patient Awareness
- Societal Pressure to Look Young Drives up Demand for Facial Aesthetics
- Cosmetic Botulinum Toxin to Feel the Pinch of the Recession
- Financing of Non-Reimbursed Healthcare: The Need of the Hour
- Combination Therapies: A Double Whammy Success
- Short Lived Aesthetic Effects: A Strong Business Case for Revision Treatments
- Consolidation Blows in the Aesthetic Healthcare Industry
- Undesirable Side Effects: A Challenge to Reckon With
- Immunogenicity Undermines Patient Compliance
- Antigenicity: One of the Most Problematic Issues in Drug Development
- Stringent Regulations Delay Market Approval & Put Reimbursements in Limbo
- Non-Injectable Alternatives to Turn On the Heat
- Fears of Terrorism & Biological Warfare Thwart International Trade
- Competition
- Allergan Wields the Scepter
- Table 1: European Market for Non-Surgical Cosmetic Procedures (2010): Percentage ShareBreakdown of Revenues by Leading Players -Allergan, Q-Med, Mentor Corporation,Mattioli Engineering, and Others (includescorresponding Graph/Chart)
- Table 2: European Market for Non-Surgical Cosmetic Procedures (2010): Percentage Breakdown of Revenuesby Type of Procedure -Cosmetic Botulinum ToxinInjections, Facial Fillers, Microdermabrasion,Chemical Peeling, and Aesthetic Lasers(includes corresponding Graph/Chart)
- Reloxin Emerges to Threaten Allergan’s Dominance
- Reloxin Vs Botox: A Comparison
- Outlook for Allergan’s Botox
- Market Share Statistics
- Global
- Table 3: World Market for Therapeutic Neurotoxins (2010): Percentage Breakdown of Revenues by Company/Brand -Botox (Allergan), Dysport (Ispen),Myobloc (Solstice), and Others (includes corresponding Graph/Chart)
- Table 4: World Market for Cosmetic Neurotoxins (2010): Percentage Breakdown of Revenues by Company/Brand -Botox/Vistabel (Allergan) and Dysport/Reloxin (Ipsen/Medicis) (includes corresponding Graph/Chart)
- Europe
- Table 5: European Market for Cosmetic Neurotoxins (2010): Percentage Breakdown of Revenues by Company/Brand -Botox/Vistabel (Allergan) and Dysport (Ipsen) (includes corresponding Graph/Chart)
- Table 6: European Market for Therapeutic Neurotoxins (2010): Percentage Breakdown of Revenues by Company/Brand -Botox (Allergan), Dysport (Ispen),and Others (includes corresponding Graph/Chart)
- United States
- Table 7: US Market for Therapeutic Neurotoxins (2010): Percentage Breakdown of Revenues by Company/Brand -Botox (Allergan) and Myobloc (Solstice) (includes corresponding Graph/Chart)
- Market Share Statistics: Through the Looking Glass: Year
- Global
- Table 8: World Market for Therapeutic Neurotoxins(2012P): Percentage Breakdown of Revenues byCompany/ Brand -Botox (Allergan), Dysport (Ispen), Myobloc (Solstice), Puretox (Mentor), Xeomin (Merz),and Others (includes corresponding Graph/Chart)
- Table 9: World Market for Cosmetic Neurotoxins (2012P): Percentage Breakdown of Revenues by Company/Brand -Botox (Allergan), Dysport/Reloxin (Ipsen/Medicis), Xeomin (Merz), and Puretox(Mentor) (includes corresponding Graph/Chart)
- United States
- Table 10: US Market for Therapeutic Neurotoxins(2012P): Percentage Breakdown of Revenues by Company/Brand -Botox (Allergan), Myobloc (Solstice),Dysport (Ispen), Puretox (Mentor) and Xeomin (Merz) (includes corresponding Graph/Chart)
- Table 11: US Market for Cosmetic Neurotoxins (2008 & 2012P): Percentage Breakdown of Revenuesby Company/ Brand -Botox (Allergan), Reloxin(Medicis), and Puretox (Mentor) (includescorresponding Graph/Chart)
- Europe
- Table 12: European Market for Therapeutic Neurotoxins (2012P): Percentage Breakdown of Revenues by Company/Brand -Botox (Allergan), Dysport (Ispen),Xeomin (Merz) and Neurobloc (Solstice) (includes corresponding Graph/Chart)
- 4. PRODUCT OVERVIEW
- Botulinum Toxin: A Poison That Cures
- Structure & Mechanism of Action
- Disadvantages
- Classification of Botulinum Toxin
- Botulinum Toxin Type A
- Historical Timeline of Botulinum Toxin: 1885-2002
- Botox®
- Key Characteristics of Botox® and Botox® Cosmetic
- Approvals and Indications of Botox in Select Regions
- Common Adverse Reactions with Botox
- Dysport®/ Reloxin®
- Key Characteristics of Dysport®
- PurTox®
- Key Characteristics of PurTox®
- Xeomin®/ NT-201
- Key Characteristics of Xeomin®/ NT-201
- Botulinum Toxin Type B
- Myobloc®/NeuroBloc®
- Key Characteristics of Myobloc®
- Applications of Botulinum Toxin
- Cosmetic Applications
- Glabellar Lines
- Facial Wrinkles
- Key Cosmetic Indications for Botulinum Toxin
- Therapeutic Applications
- Movement Disorders/Pain
- Cervical Dystonia
- Hemifacial Spasm
- Blepharospasm
- Strabismus
- Chronic Pain
- Botox in Migraine Treatment
- Hyperhidrosis
- Bladder Dysfunctions
- Spasticity
- Other Applications
- 5. PRODUCT APPROVALS & INTRODUCTIONS
- SMC Approves the Use of Botox® for the Treatment of Focal Spasticity
- Merz Launches Xeomin in the US
- Ipsen Launches Dysport in US
- Ipsen and Medicis Receives FDA Approval for DysportTM
- Xeomin Receives Approval From European Health Authorities
- Ranbaxy and MedyTox Collaborates to Launch Neuronox
- GlaxoSmithKline Receives Approval for Botox Vista
- Galderma and Ipsen Obtain Marketing Authorization for Azzalure
- Azzalure® Gains Approval from 15 European Countries
- Inclusion of New Side Effect in Botox and Botox Cosmetic Labels
- Azzalure® Gains Approval for Aesthetic Application in the UK
- Ipsen and Medicis File BLA for Reloxin®
- Allergan and Clinique Launch New Skin Care Products
- FDA Accepts Ipsen's Filing for Reloxin
- GlaxoSmithKline Gains Approval for BOTOX® in Japan
- Mentor Completes Phase IIIb Trial for Its Botulinum Toxin Type A Product
- Allergan Commences Botox Study for Urological Cases in India
- FDA Accepts BLA Filing for Dysport® in Cervical Dystonia Cases
- Allergan Successfully Completes Analysis of Two Phase III Trials for BOTOX®
- Allergan to Launch New Products in India
- 6. RECENT INDUSTRY ACTIVITY
- US WorldMeds Takes Over Solstice Neurosciences
- Johnson & Johnson Acquires Mentor Corporation
- Ranbaxy Signs an in-Licensing Agreeement with Medy-Tox
- Ranbaxy Signs Marketing Agreement with MedyTox
- Revance and Medicis Sign Licensing Agreement
- GlaxoSmithKline and Wakamoto Pharmaceutical Collaborate to Market Botox
- BioForm Medical Acquires Advanced Cosmetic Intervention
- Galderma to Acquire CollaGenex
- Allergan and Clinique Form Strategic Collaboration
- Allergan to Set Up a New Subsidiary in India
- Allergan Join Hands with India-Based Kaya
- Q-Med and Medy-Tox Cancel the Collaboration Agreement
- Galderma to Increase Awareness in Brazil
- Galderma Receives License to Market Dysport
- 7. FOCUS ON SELECT KEY PLAYERS
- Allergan, Inc (US)
- Ipsen Group (France)
- Lanzhou Institute of Biological Products (China)
- Metabiologics Inc, (US)
- Merz Pharmaceuticals GmbH (Germany)
- Mentor Corporation (US)
- Medy-Tox Incorporated (South Korea)
- Medicis Pharmaceutical Corporation (US)
- Solstice Neurosciences, Inc. (US)
- 8. GLOBAL MARKET PERSPECTIVE
- Table 13: World Recent Past, Current & Future Analysisfor Botulinum Toxin by Geographic Region/Country -US, Europe and Rest of World Markets IndependentlyAnalyzed by Annual Sales in US$ Millionfor the Years 2009 through 2017 (includescorresponding Graph/Chart)
- Table 14: World Historic Review for Botulinum Toxin byGeographic Region/Country - US, Europe and Rest of WorldMarkets Independently Analyzed by Annual Salesin US$ Million For the Years 2003 through 2008(includes corresponding Graph/Chart)
- Table 15: World 15-Year Perspective for Botulinum Toxin by Geographic Region - Percentage Breakdownof Dollar Sales for US, Europe and Rest of World Marketsfor the Years 2003, 2010 & 2017 (includescorresponding Graph/Chart)
- Table 16: World Recent Past, Current & Future Analysisfor Botulinum Toxin in Cosmetic Applications by GeographicRegion - US, Europe and Rest of World Markets Independently Analyzed by Annual Sales in US$ Million for the Years 2009through 2017 (includes corresponding Graph/Chart)
- Table 17: World Historic Review for Botulinum Toxin in Cosmetic Applications by Geographic Region - US, Europeand Rest of World Markets Independently Analyzed byAnnual Sales in US$ Million for the Years 2003 through2008 (includes corresponding Graph/Chart)
- Table 18: World 15-Year Perspective for Botulinum Toxinin Cosmetic Applications by Geographic Region - Percentage Breakdown of Dollar Sales for US, Europe and Rest of World Markets for the Years 2003, 2010 &2017 (includes corresponding Graph/Chart)
- Table 19: World Recent Past, Current & Future Analysisfor Botulinum Toxin in Therapeutic Applications byGeographic Region - US, Europe and Rest of WorldMarkets Independently Analyzed by Annual Salesin US$ Million for the Years 2009 through 2017(includes corresponding Graph/Chart)
- Table 20: World Historic Review for Botulinum Toxinin Therapeutic Applications by Geographic Region - US,Europe and Rest of World Markets Independently Analyzedby Annual Sales in US$ Million for the Years 2003 through2008 (includes corresponding Graph/Chart)
- Table 21: World 15-Year Perspective for Botulinum Toxin in Therapeutic Applications by Geographic Region - Percentage Breakdown of Dollar Sales for US, Europe and Rest of World Markets for the Years 2003, 2010 &2017 (includes corresponding Graph/Chart)
- Table 22: World Recent Past, Current & Future Analysisfor Botulinum Toxin in Therapeutic Application by Disease Indication - Movement Disorders/Pain, Headache,Hyperhidrosis, Overactive Bladder and Spasticity-Markets Analyzed with Annual Sales Figuresin US$ Million for Years 2009 through 2017(includes corresponding Graph/Chart)
- Table 23: Global Historic Review for Botulinum Toxin in Therapeutic Application by Disease Indication -Movement Disorders/Pain, Headache, Hyperhidrosis,Overactive Bladder and Spasticity- MarketsAnalyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includescorresponding Graph/Chart)
- Table 24: World 15-Year Perspective for Botulinum Toxin in Therapeutic Application by Disease Indication - Percentage Breakdown of Dollar Salesfor Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder and Spasticity - Marketsfor the Years 2003, 2010 & 2017 (includescorresponding Graph/Chart)
- 9. THE UNITED STATES
- A. Market Analysis
- Current and Future Scenario
- By Application
- Cosmetic Procedures: An Overview
- Botox Leads the US Botulinum Toxin Market
- Botox Approvals and Indications in the US
- Major Market Trends
- Botulinum Toxin to Drive Growth in the Facial Aesthetics Market
- Booming Non-Surgical Treatments
- Aging Baby Boomers Drive Aesthetic Business
- Expanding Physician Base Extends Impetus to Growth
- Demand for Professional Help On the Rise
- Direct-to-Consumer Advertising Drive Cosmetic Botulinum Toxin
- Botulism Poisoning: A Major Concern
- Botox Injection - Popular Non-Invasive Cosmetic Procedure
- Product Approvals and Introductions
- Strategic Corporate Developments
- Key Players
- B. Market Analytics
- Table 25: US Recent Past, Current & Future Analysis for Botulinum Toxin by Application - CosmeticApplications and Therapeutic Applications Markets Independently Analyzed by Annual Sales Figuresin US$ Million for the Years 2009 through 2017(includes corresponding Graph/Chart)
- Table 26: US Historic Review for Botulinum Toxinby Application - Cosmetic Applications andTherapeutic Applications Markets Independently Analyzed by Annual Sales Figures in US$ Millionfor the Years 2003 through 2008 (includescorresponding Graph/Chart)
- Table 27: US 15-Year Perspective for Botulinum Toxinby Application - Percentage Breakdown of Dollar Salesfor Cosmetic Applications and Therapeutic Applications Markets for the Years 2003, 2010 & 2017 (includes corresponding Graph/Chart)
- Table 28: US Recent Past, Current & Future Analysis for Botulinum Toxin in Therapeutic Applications by Disease Indication - Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder and Spasticity- Markets Independently Analyzed by Annual SalesFigures in US$ Million for the Years 2009 through2017 (includes corresponding Graph/Chart)
- Table 29: US Historic Review for Botulinum Toxin in Therapeutic Application by Disease Indication -Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder and Spasticity MarketsIndependently Analyzed with Annual Sales Figuresin US$ Million for Years 2003 through 2008(includes corresponding Graph/Chart)
- Table 30: US 15-Year Perspective for Botulinum Toxinin Therapeutic Application by Disease Indication - Percentage Breakdown of Dollar Sales for Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder and Spasticity for the Years 2003, 2010 &2017 (includes corresponding Graph/Chart)
- 10. EUROPE
- A. Market Analysis
- Current and Future Scenario
- By Application
- European BTX Cosmetics Treatments Market - A Primer
- Botox Approvals and Indications in Select European Countries
- Botox to Support Radiation Treatments
- Product Approvals and Introductions
- Key Players
- B. Market Analytics
- Table 31: European Recent Past, Current & FutureAnalysis for Botulinum Toxin by Application -Cosmetic Applications and Therapeutic ApplicationsMarkets Independently Analyzed by Annual SalesFigures in US$ Million for the Years 2009 through2017 (includes corresponding Graph/Chart)
- Table 32: European Historic Review for Botulinum Toxinby Application -Cosmetic Applications and Therapeutic Applications Markets Independently Analyzed by Annual Sales Figures in US$ Million for the Years 2003 through 2008 (includes corresponding Graph/Chart)
- Table 33: European 15-Year Perspective for BotulinumToxin by Application - Percentage Breakdown of Dollar Sales for Cosmetic Applications and TherapeuticApplications Markets for the Years 2003, 2010 &2017 (includes corresponding Graph/Chart)
- Table 34: European Recent Past, Current & FutureAnalysis for Botulinum Toxin in Therapeutic Applicationsby Disease Indication - Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder andSpasticity- Markets Independently Analyzed byAnnual Sales Figures in US$ Millionfor the Years 2009 through 2017 (includescorresponding Graph/Chart)
- Table 35: European Historic Review for Botulinum Toxin in Therapeutic Application by Disease Indication - Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder and Spasticity - Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
- Table 36: European 15-Year Perspective for Botulinum Toxinin Therapeutic Application by Disease Indication - Percentage Breakdown of Dollar Sales for Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder and Spasticity- Markets for the Years 2003,2010 & 2017 (includes corresponding Graph/Chart)
- 11. REST OF WORLD
- A. Market Analysis
- Current and Future Scenario
- By Applications
- A Peek into Select Markets
- India - An Emerging Market for Botox
- Competitive Landscape in South Korea
- Table 37: Korean Botulinum Toxin Market (2010): Percentage Breakdown of Sales by Leading Players -Medy-Tox, Allergan, Ipsen, and Lanzhou Institute (includes corresponding Graph/Chart)
- Australia - A Well Supported Market
- Botox Approvals and Indications in Select Asian Countries
- Latin America- Cosmetic Surgery Market
- Botox Approvals and Indications in Select Latin American Regions
- Botox Approvals and Indications in Other Select Global Regions
- Product Approvals and Introductions
- Strategic Corporate Developments
- Key Players
- B. Market Analytics
- Table 38: Rest of World Recent Past, Current & Future Analysis for Botulinum Toxin by Application - Cosmetic Applications and Therapeutic Applications Markets Independently Analyzed by Annual Sales Figuresin US$ Million for the Years 2009 through 2017) (includes corresponding Graph/Chart)
- Table 39: Rest of World Historic Review for Botulinum Toxinby Application - Cosmetic Applications and Therapeutic Applications Markets Independently Analyzed by Annual Sales Figures in US$ Million for the Years 2003 through 2008 (includes corresponding Graph/Chart)
- Table 40: Rest of World 15-Year Perspective for Botulinum Toxin by Application - Percentage Breakdown of Dollar Sales for Cosmetic Applications and TherapeuticApplications Markets for the Years 2003, 2010 &2017 (includes corresponding Graph/Chart)
- Table 41: Rest of World Recent Past, Current & FutureAnalysis for Botulinum Toxin in Therapeutic Applicationsby Disease Indication - Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder andSpasticity- Markets Independently Analyzed by AnnualSales Figures in US$ Million for the Years 2009through 2017 (includes corresponding Graph/Chart)
- Table 42: Rest of World Historic Review for BotulinumToxin in Therapeutic Application by DiseaseIndication - Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder and SpasticityMarkets Independently Analyzed with Annual SalesFigures in US$ Million for Years 2003 through2008 (includes corresponding Graph/Chart)
- Table 43: Rest of World 15-Year Perspective for Botulinum Toxin in Therapeutic Application byDisease Indication - Percentage Breakdown ofDollar Sales for Movement Disorders/Pain,Headache, Hyperhidrosis, Overactive Bladderand Spasticity for the Years 2003, 2010 & 2017(includes corresponding Graph/Chart)
- COMPETITIVE LANDSCAPE
- Total Companies Profiled: 19 (including Divisions/Subsidiaries - 22)Region/Country Players
- The United States
- Japan 2
- Europe
- France
- Germany
- The United Kingdom
- Rest of Europe 1
- Asia-Pacific (Excluding Japan)
AbstractThis report analyzes the worldwide markets for Botulinum Toxin in US$ Million by the following Product Segments: Cosmetic Applications, and Therapeutic Applications (Movement Disorders/Pain, Headache, Hyperhidrosis, Overactive Bladder, & Spasticity). The report provides separate comprehensive analytics for the US, Japan, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2017. Also, a six-year historic analysis is provided for these markets.The report profiles 19 companies including many key and niche players such as Allergan, Inc., Ipsen Group, Lanzhou Institute of Biological Products, Metabiologics, Inc., Merz Pharmaceuticals GmbH, Mentor Corporation, Medy-Tox Incorporated, Medicis Pharmaceutical Corporation, and Solstice Neurosciences, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.
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