The Global Market for Pain Management Drugs and Devices

Published by: BCC Research

Published: Aug. 1, 2009 - 213 Pages

Table of Contents

CHAPTER ONE: INTRODUCTION

STUDY GOALS AND OBJECTIVES

REASONS FOR DOING THE STUDY

SCOPE OF REPORT

METHODOLOGY

ANALYST CREDENTIALS

RELATED BCC STUDIES

BCC RESEARCH ONLINE SERVICES

DISCLAIMER

CHAPTER TWO: SUMMARY

SUMMARY TABLE WORLDWIDE PAIN MANAGEMENT PHARMACEUTICALS AND DEVICES MARKET AT MANUFACTURERS’ SALES LEVELS, THROUGH 2013 ($ MILLIONS)

SUMMARY FIGURE WORLDWIDE PAIN MANAGEMENT PHARMACEUTICALS AND DEVICES MARKET AT MANUFACTURERS’ SALES LEVELS, 2006-2013 ($ MILLIONS)

CHAPTER THREE: INDUSTRY OVERVIEW

HISTORY OF PAIN AND PAIN TREATMENT

THE PERCEPTION OF PAIN

Types of Pain

Acute Pain

Chronic Pain

ASSESSMENT OF PAIN

Subjective

Objective

TABLE 1 OBJECTIVE SIGNS OF PAIN

HOW PAIN IS DIAGNOSED

THERMOGRAPHY

HOW PAIN IS TREATED

FIGURE 1 PAIN-MANAGEMENT TECHNIQUES

THE AGING U.S. POPULATION

TABLE 2 U.S. POPULATION ESTIMATES BY AGE GROUP AND GENDER, 1950 AND 2000 (MILLIONS)

FIGURE 2 U.S. POPULATION ESTIMATES, BY AGE GROUP, 1950 AND 2000 (MILLIONS)

FIGURE 3 U.S. POPULATION ESTIMATES BY GENDER, 1950 AND 2000 (MILLIONS)

TABLE 3 U.S. POPULATION PROJECTIONS BY AGE GROUP AND GENDER FOR SPECIFIC YEARS, 2010-2050 (MILLIONS)

FIGURE 4 U.S. POPULATION PROJECTIONS, BY SELECTED AGE GROUP FOR SPECIFIC YEARS, 2010-2050 (MILLIONS)

FIGURE 5 U.S. POPULATION PROJECTIONS, BY GENDER FOR SPECIFIC YEARS, 2010-2050 (MILLIONS)

WORLD DEMOGRAPHICS

TABLE 4 WORLD POPULATION GROWTH BY GEOGRAPHICAL REGION, 2008 AND 2013 (MILLIONS)

FIGURE 6 WORLD POPULATION BY GEOGRAPHICAL REGION, 2008 AND 2013 (MILLIONS)

TABLE 5 ESTIMATED AND PROJECTED WORLD POPULATION BY AGE AND GENDER, 2008 AND 2013

FIGURE 7 ESTIMATED AND PROJECTED WORLD POPULATION BY AGE AND GENDER, 2008 AND 2013 (MILLIONS)

LIFE EXPECTANCY FOR MEN AND WOMEN

TABLE 6 CURRENT AND PROJECTED U.S. LIFE EXPECTANCY AT BIRTH BY GENDER AND YEAR, 2000-2020 (YEARS)

FIGURE 8 CURRENT AND PROJECTED U.S. LIFE EXPECTANCY AT BIRTH BY GENDER AND YEAR, 2000-2020 (YEARS)

INCIDENCE OF PAIN

PREVALENCE OF PAIN

Severe Headache or Migraine, Low Back, and Neck Pain

TABLE 7 SEVERE HEADACHE OR MIGRAINE, LOW BACK PAIN, AND NECK PAIN AMONG ADULTS, 18 YEARS OF AGE AND OVER*, 1997-2009 (%)

FIGURE 9 SEVERE HEADACHE OR MIGRAINE, LOW BACK PAIN, AND NECK PAIN AMONG ADULTS, 18 YEARS OF AGE AND OVER*, 1997-2009 (%)

Joint Pain

TABLE 8 JOINT PAIN AMONG ADULTS 18 YEARS OF AGE AND OVER*, 2002-2009 (%)

FIGURE 10 JOINT PAIN AMONG ADULTS 18 YEARS OF AGE AND OVER*, 2002-2009 (%)

Cancer Pain

FIGURE 11 CAUSES OF CANCER PAIN

Pain Management in Cancer

TABLE 9 CANCER PAIN MEDICATION

Description of Some of Key Medications for Cancer Pain Control

• Morphine

• Fentanyl

• Hydromorphone

• Methadone

• Buprenorphine

• Oxycodone

• Diamorphine

HIV/AIDS Related Pain

TABLE 10 ESTIMATED HIV REPORTED CASES BY SELECTED CHARACTERISTICS, 2007

FIGURE 12 ESTIMATED HIV REPORTED CASES BY AGE GROUP, 2007

FIGURE 13 ESTIMATED HIV REPORTED CASES BY GENDER, 2007

FIGURE 14 ESTIMATED HIV REPORTED CASES BY RACE, 2007

Burn Pain

Burn Classifications

TABLE 11 BURN CLASSIFICATIONS

Stages of Burn Healing

Challenges Associated with Burn Pain

Burn Pain Management

FIGURE 15 BURN PAIN MANAGEMENT APPROACH

Dental Pain

Treatment for Dental Pain

GENDER AND PAIN

TABLE 12 PAIN BY SELECTED CATEGORY AND GENDER IN THE 18+ U.S. POPULATION*, 1997-2006 (%)

FIGURE 16 PAIN BY SELECTED CATEGORY AND GENDER IN THE 18+ U.S. POPULATION*, 1997-2006 (%)

OTHER INFLUENCES DETERMINING HOW PAIN IS FELT AMONG INDIVIDUALS

Objective Pain Measurement

OBSTETRICS PAIN

ORTHOPEDIC PAIN

PEDIATRIC PAIN

SURGICAL PAIN

GLOBAL PAIN MANAGEMENT

CHAPTER FOUR: INDUSTRY TRENDS

OVERVIEW

UNDERTREATMENT ISSUES

TREATMENT OF PAIN AND ISSUES FACING THE PROFESSIONAL SEGMENT

TABLE 13 NUMBER OF PHYSICIAN GRADUATES FROM 1990-2006 (THOUSANDS)

TABLE 14 NUMBER OF PHYSICIANS PER 100,000 RESIDENT POPULATION, 2006

TABLE 15 TOTAL NUMBER OF ABUSE TREATMENT FACILITIES AND CLIENTS, 2000-2007

FIGURE 17 TOTAL NUMBER OF ABUSE TREATMENT FACILITIES, 2000-2007

FIGURE 18 TOTAL NUMBER OF ABUSE TREATMENT CLIENTS, 2000-2007

TABLE 16 BENEFITS OF PRESCRIPTION MONITORING PROGRAMS FOR MEDICAL BOARDS

TABLE 17 STATES WITH ELECTRONIC PRESCRIPTION MONITORING PROGRAMS

FIGURE 19 TOTAL NUMBER OF STATES WITH ELECTRONIC PRESCRIPTION MONITORING PROGRAMS BY YEAR OF ENACTMENT

TABLE 18 STATE CONTROLLED SUBSTANCES SCHEDULING AUTHORITIES AND OTHER CONTACT INFORMATION

MANAGED CARE PAIN MANAGEMENT ISSUES

PRODUCT PIPELINE

TABLE 19 PAIN-MANAGEMENT DRUG PRODUCT PIPELINES

NEW DEVELOPMENTS IN BREAKTHROUGH CANCER PAIN

OPIOID-INDUCED CONSTIPATION AND REDUCED COMPLIANCE

PATENT EXPIRATION

TABLE 20 U.S. PATENT EXPIRATION DATES FOR SELECT PAIN DRUGS

GENERIC PARTICIPATION

TABLE 21 FIRST TIME PRESCRIPTION GENERIC PAIN MANAGEMENT AND APPROVALS, JANUARY 2004-APRIL 2009

NEW FDA APPROVAL REQUIREMENTS FOR PAIN THERAPIES

FUTURE OF PAIN RESEARCH

OF PAIN RESEARCH (CONTINUED)

PATIENT OUTCOMES RESEARCH

DRUG DELIVERY SYSTEMS

Oral and Extended Release

Topical and Transdermal

Intravenous

Patient-Controlled Analgesia

Iontophoresis

TABLE 22 ADVANTAGES OF IONTOPHORETIC DRUG DELIVERY

Electromechanical Transport

CHAPTER FIVE: TREATING PAIN

PHARMACEUTICAL PAIN MANAGEMENT

PRESCRIPTION PAIN MANAGEMENT PRODUCTS

Analgesic Drugs

Non-Narcotic

Narcotic

Full and Partial Agonists

Agonist-Antagonists

Nonsteroid Anti-inflammatory Drugs

Anti-migraine Drugs

TABLE 23 RECENT APPLICATIONS/APPROVALS, THROUGH 3/2009

Antidepressant, Anticonvulsants, and Other Pain Relieving Drugs

ANESTHETICS

General

TABLE 24 MOST COMMONLY USED GENERAL ANESTHETIC AGENTS

Topical

OVER-THE-COUNTER PAIN MANAGEMENT PRODUCTS

ANALGESIC DRUGS

TABLE 25 ACETAMINOPHEN AND ACETAMINOPHEN COMBINATION PRODUCTS

NONSTEROID ANTI-INFLAMMATORY DRUGS

Aspirin Products and Aspirin Combination Products

TABLE 26 ASPIRIN AND ASPIRIN COMBINATION PRODUCTS

Ibuprofen and Ibuprofen Combination Products

TABLE 27 IBUPROFEN AND IBUPROFEN COMBINATION PRODUCTS

Ketoprofen Products

TABLE 28 KETOPROFEN PRODUCTS

Naproxen Compounds

TABLE 29 OTC NONSTEROID ANTI-INFLAMMATORIES

ANTI-MIGRAINE DRUGS

TABLE 30 ANTI-MIGRAINE PRODUCTS

TOPICAL ANESTHETIC DRUGS

TABLE 31 TOPICAL ANESTHETIC PRODUCTS

PAIN MANAGEMENT DEVICES

TRANSCUTANEOUS ELECTRICAL NERVE STIMULATORS

PAIN TEM

SPINAL CORD STIMULATORS

NEUROMUSCULAR STIMULATORS

OTHER PAIN MANAGEMENT DEVICES

PAIN MANAGEMENT PROCEDURES

ALTERNATIVE METHODS OF PAIN MANAGEMENT

Psychological Therapies

Biofeedback

Hypnosis

Behavior Modification/Operant Conditioning

Relaxation and Stress Management Training

Imagery

Autogenic Training

Psychosocial Interventions

Distraction and Reframing

Ice 116

Warm Bath

Massage

Joint Mobilization

Manipulation

Traction

Acupuncture/Acupressure

Laser Therapy

Surgery

Radiation Therapy

Radio Frequency Neuroablation, Epiduroscopy

PAIN MANAGEMENT SERVICES

HOME CARE

HOSPICE

NATIONAL HOSPICE ORGANIZATION

TABLE 32 NHO COMMITTEES

HOSPITALS

PAIN CLINICS

SKILLED NURSING FACILITIES

CHAPTER SIX: PRESCRIPTION PAIN MANAGEMENT MARKET SIZE AND ANALYSIS

TOTAL MARKET

PRESCRIPTION PAIN MARKETS BY PRODUCT TYPE

TABLE 33 WORLDWIDE PRESCRIPTION PAIN MANAGEMENT PHARMACEUTICALS MARKET, THROUGH 2013 ($ MILLIONS)

FIGURE 20 WORLDWIDE PRESCRIPTION PAIN MANAGEMENT PHARMACEUTICALS MARKET, 2006-2013 ($ MILLIONS)

MARKET PARTICIPANTS

TABLE 34 GLOBAL PRESCRIPTION NARCOTIC AND NSAIDS MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 ($ MILLIONS)

FIGURE 21 GLOBAL PRESCRIPTION NARCOTIC AND NSAIDS MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 ($ MILLIONS)

TABLE 35 GLOBAL PRESCRIPTION ANTI-MIGRAINE DRUG MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 ($ MILLIONS)

FIGURE 22 GLOBAL PRESCRIPTION ANTI-MIGRAINE DRUG MANUFACTURER MARKET SHARE BY REVENUE, 2008 (%)

TABLE 36 GLOBAL PRESCRIPTION ANESTHESIA MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 ($ MILLIONS)

FIGURE 23 GLOBAL PRESCRIPTION ANESTHESIA MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 (%)

FUTURE MARKET ANALYSIS

CHAPTER SEVEN: PAIN MANAGEMENT DEVICE MARKET SIZE AND ANALYSIS

TOTAL PAIN MANAGEMENT DEVICE MARKET

PAIN MARKETS BY PRODUCT TYPE

TABLE 37 GLOBAL PAIN MANAGEMENT DEVICES MARKET AT MANUFACTURERS’ SALES LEVELS BY PRODUCT TYPE, THROUGH 2013 ($ MILLIONS)

FIGURE 24 GLOBAL PAIN MANAGEMENT DEVICES MARKET BY PRODUCT TYPE, THROUGH 2013 ($ MILLIONS)

MARKET PARTICIPANTS

TABLE 38 GLOBAL NEUROMUSCULAR STIMULATOR/TENS MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 ($ MILLIONS)

FIGURE 25 GLOBAL NEUROMUSCULAR STIMULATOR/TENS UNIT MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 (%)

TABLE 39 GLOBAL SPINAL CORD STIMULATOR MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008

FIGURE 26 GLOBAL SPINAL CORD STIMULATOR MANUFACTURER MARKET SHARE, 2008 (%)

FUTURE MARKET ANALYSIS

CHAPTER EIGHT: TOTAL MARKET SUMMARY

TOTAL PAIN MANAGEMENT MARKET

TABLE 40 GLOBAL PAIN MANAGEMENT PHARMACEUTICALS AND DEVICES MARKET BY CATEGORY, THROUGH 2013 ($ MILLIONS)

FIGURE 27 GLOBAL PAIN MANAGEMENT PHARMACEUTICALS AND DEVICES MARKET BY CATEGORY, 2006-2013 ($ MILLIONS)

MARKET PERCENTAGE BY PRODUCT TYPE

TABLE 41 PERCENT DISTRIBUTION OF THE WORLDWIDE PAIN MANAGEMENT MARKET BY SEGMENT, 2008 (%, $ MILLIONS)

FIGURE 28 PERCENT DISTRIBUTION OF THE WORLDWIDE PAIN MANAGEMENT MARKET BY SEGMENT, 2008 (%)

CHAPTER NINE: COMPANY PROFILES

PHARMACEUTICAL PAIN MANAGEMENT MANUFACTURERS

ABBOTT LABORATORIES

ASTRAZENECA

BARR LABORATORIES, INC

BAXTER INTERNATIONAL

BRISTOL-MYERS SQUIBB CO

ELI LILLY & CO

GLAXOSMITHKLINE

MEDTRONIC, INC.

MERCK & CO., INC

ORTHO-MCNEIL PHARMACEUTICALS

PFIZER

WYETH

APPENDIX I: SELECTED PAIN MANAGEMENT CLINICS BY STATE

PAIN CLINICS

TABLE 42 ALABAMA CLINICS

TABLE 43 CALIFORNIA PAIN CLINICS

TABLE 44 COLORADO PAIN CLINICS

TABLE 45 DELAWARE PAIN CLINICS

TABLE 46 FLORIDA PAIN CLINICS

TABLE 47 HAWAII PAIN CLINICS

TABLE 48 IOWA PAIN CLINICS

TABLE 49 MAINE PAIN CLINICS

TABLE 50 NEVADA PAIN CLINICS

TABLE 51 OREGON PAIN CLINICS

TABLE 52 PENNSYLVANIA PAIN CLINICS

TABLE 53 RHODE ISLAND PAIN CLINICS

TABLE 54 SOUTH DAKOTA PAIN CLINICS

TABLE 55 TEXAS PAIN CLINICS

TABLE 56 WASHINGTON PAIN CLINICS

PAIN SOCIETIES AND ASSOCIATIONS

INTERNATIONAL ASSOCIATIONS AND ORGANIZATIONS

APPENDIX II: COMPANY NAMES AND ADDRESSES

PAIN MANAGEMENT PHARMACEUTICAL MANUFACTURERS

LIST OF TABLES

SUMMARY TABLE WORLDWIDE PAIN MANAGEMENT

PHARMACEUTICALS AND DEVICES MARKET AT

MANUFACTURERS’ SALES LEVELS, THROUGH 2013 ($ MILLIONS)

TABLE 1 OBJECTIVE SIGNS OF PAIN

TABLE 2 U.S. POPULATION ESTIMATES BY AGE GROUP AND

GENDER, 1950 AND 2000 (MILLIONS)

TABLE 3 U.S. POPULATION PROJECTIONS BY AGE GROUP AND

GENDER FOR SPECIFIC YEARS, 2010-2050 (MILLIONS)

TABLE 4 WORLD POPULATION GROWTH BY GEOGRAPHICAL

REGION, 2008 AND 2013 (MILLIONS)

TABLE 5 ESTIMATED AND PROJECTED WORLD POPULATION BY

AGE AND GENDER, 2008 AND 2013 (MILLIONS)

TABLE 6 CURRENT AND PROJECTED U.S. LIFE EXPECTANCY AT

BIRTH BY GENDER AND YEAR, 2000-2020 (YEARS)

TABLE 7 SEVERE HEADACHE OR MIGRAINE, LOW BACK PAIN, AND

NECK PAIN AMONG ADULTS, 18 YEARS OF AGE AND OVER*, 1997-

2009 (%)

TABLE 8 JOINT PAIN AMONG ADULTS 18 YEARS OF AGE AND OVER*,

2002-2009 (%)

TABLE 9 CANCER PAIN MEDICATION

TABLE 10 ESTIMATED HIV REPORTED CASES BY SELECTED

CHARACTERISTICS, 2007

TABLE 11 BURN CLASSIFICATIONS

TABLE 12 PAIN BY SELECTED CATEGORY AND GENDER IN THE 18+

U.S. POPULATION*, 1997-2006 (%)

TABLE 13 NUMBER OF PHYSICIAN GRADUATES FROM 1990-2006

(THOUSANDS)

TABLE 14 NUMBER OF PHYSICIANS PER 100,000 RESIDENT

POPULATION, 2006

TABLE 15 TOTAL NUMBER OF ABUSE TREATMENT FACILITIES AND

CLIENTS, 2000-2007

TABLE 16 BENEFITS OF PRESCRIPTION MONITORING PROGRAMS

FOR MEDICAL BOARDS

TABLE 17 STATES WITH ELECTRONIC PRESCRIPTION MONITORING

PROGRAMS

TABLE 18 STATE CONTROLLED SUBSTANCES SCHEDULING

AUTHORITIES AND OTHER CONTACT INFORMATION

TABLE 19 PAIN-MANAGEMENT DRUG PRODUCT PIPELINES

TABLE 20 U.S. PATENT EXPIRATION DATES FOR SELECT PAIN

DRUGS

TABLE 21 FIRST TIME PRESCRIPTION GENERIC PAIN MANAGEMENT

AND APPROVALS, JANUARY 2004-APRIL 2009

TABLE 22 ADVANTAGES OF IONTOPHORETIC DRUG DELIVERY

TABLE 23 RECENT APPLICATIONS/APPROVALS, THROUGH 3/2009

TABLE 24 MOST COMMONLY USED GENERAL ANESTHETIC AGENTS

TABLE 25 ACETAMINOPHEN AND ACETAMINOPHEN COMBINATION

PRODUCTS

TABLE 26 ASPIRIN AND ASPIRIN COMBINATION PRODUCTS

TABLE 27 IBUPROFEN AND IBUPROFEN COMBINATION PRODUCTS

TABLE 28 KETOPROFEN PRODUCTS

TABLE 29 OTC NONSTEROID ANTI-INFLAMMATORIES

TABLE 30 ANTI-MIGRAINE PRODUCTS

TABLE 31 TOPICAL ANESTHETIC PRODUCTS

TABLE 32 NHO COMMITTEES

TABLE 33 WORLDWIDE PRESCRIPTION PAIN MANAGEMENT

PHARMACEUTICALS MARKET, THROUGH 2013 ($ MILLIONS)

TABLE 34 GLOBAL PRESCRIPTION NARCOTIC AND NSAIDS

MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 ($

MILLIONS)

TABLE 35 GLOBAL PRESCRIPTION ANTI-MIGRAINE DRUG

MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 ($

MILLIONS)

TABLE 36 GLOBAL PRESCRIPTION ANESTHESIA MANUFACTURER

MARKET SHARE BY MANUFACTURER, 2008 ($ MILLIONS)

TABLE 37 GLOBAL PAIN MANAGEMENT DEVICES MARKET AT

MANUFACTURERS’ SALES LEVELS BY PRODUCT TYPE, THROUGH

2013 ($ MILLIONS)

TABLE 38 GLOBAL NEUROMUSCULAR STIMULATOR/TENS

MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 ($

MILLIONS)

TABLE 39 GLOBAL SPINAL CORD STIMULATOR MANUFACTURER

MARKET SHARE BY MANUFACTURER, 2008 ($ MILLIONS)

TABLE 40 GLOBAL PAIN MANAGEMENT PHARMACEUTICALS AND

DEVICES MARKET BY CATEGORY, THROUGH 2013 ($ MILLIONS)

TABLE 41 PERCENT DISTRIBUTION OF THE WORLDWIDE PAIN

MANAGEMENT MARKET BY SEGMENT, 2008 (%, $ MILLIONS)

TABLE 42 ALABAMA CLINICS

TABLE 43 CALIFORNIA PAIN CLINICS

TABLE 44 COLORADO PAIN CLINICS

TABLE 45 DELAWARE PAIN CLINICS

TABLE 46 FLORIDA PAIN CLINICS

TABLE 47 HAWAII PAIN CLINICS

TABLE 48 IOWA PAIN CLINICS

TABLE 49 MAINE PAIN CLINICS

TABLE 50 NEVADA PAIN CLINICS

TABLE 51 OREGON PAIN CLINICS

TABLE 52 PENNSYLVANIA PAIN CLINICS

TABLE 53 RHODE ISLAND PAIN CLINICS

TABLE 54 SOUTH DAKOTA PAIN CLINICS

TABLE 55 TEXAS PAIN CLINICS

TABLE 56 WASHINGTON PAIN CLINICS

LIST OF FIGURES

SUMMARY FIGURE WORLDWIDE PAIN MANAGEMENT

PHARMACEUTICALS AND DEVICES MARKET AT

MANUFACTURERS’ SALES LEVELS, 2006-2013 ($ MILLIONS)

FIGURE 1 PAIN-MANAGEMENT TECHNIQUES

FIGURE 2 U.S. POPULATION ESTIMATES, BY AGE GROUP, 1950 AND

2000 (MILLIONS)

FIGURE 3 U.S. POPULATION ESTIMATES BY GENDER, 1950 AND 2000

(MILLIONS)

FIGURE 4 U.S. POPULATION PROJECTIONS, BY SELECTED AGE

GROUP FOR SPECIFIC YEARS, 2010-2050 (MILLIONS)

FIGURE 5 U.S. POPULATION PROJECTIONS, BY GENDER FOR

SPECIFIC YEARS, 2010-2050 (MILLIONS)

FIGURE 6 WORLD POPULATION BY GEOGRAPHICAL REGION, 2008

AND 2013 (MILLIONS)

FIGURE 7 ESTIMATED AND PROJECTED WORLD POPULATION BY

AGE AND GENDER, 2008 AND 2013 (MILLIONS)

FIGURE 8 CURRENT AND PROJECTED U.S. LIFE EXPECTANCY AT

BIRTH BY GENDER AND YEAR, 2000-2020 (YEARS)

FIGURE 9 SEVERE HEADACHE OR MIGRAINE, LOW BACK PAIN, AND

NECK PAIN AMONG ADULTS, 18 YEARS OF AGE AND OVER*, 1997-

2009 (%)

FIGURE 10 JOINT PAIN AMONG ADULTS 18 YEARS OF AGE AND

OVER*, 2002-2009 (%)

FIGURE 11 CAUSES OF CANCER PAIN

FIGURE 12 ESTIMATED HIV REPORTED CASES BY AGE GROUP, 2007

FIGURE 13 ESTIMATED HIV REPORTED CASES BY GENDER, 2007

FIGURE 14 ESTIMATED HIV REPORTED CASES BY RACE, 2007

FIGURE 15 BURN PAIN MANAGEMENT APPROACH

FIGURE 16 PAIN BY SELECTED CATEGORY AND GENDER IN THE 18+

U.S. POPULATION*, 1997 AND 2006 (%)

FIGURE 17 TOTAL NUMBER OF ABUSE TREATMENT FACILITIES,

2000-2007

FIGURE 18 TOTAL NUMBER OF ABUSE TREATMENT CLIENTS, 2000-

2007

FIGURE 19 TOTAL NUMBER OF STATES WITH ELECTRONIC

PRESCRIPTION MONITORING PROGRAMS BY YEAR OF

ENACTMENT

FIGURE 20 WORLDWIDE PRESCRIPTION PAIN MANAGEMENT

PHARMACEUTICALS MARKET, 2006-2013 ($ MILLIONS)

FIGURE 21 GLOBAL PRESCRIPTION NARCOTIC AND NSAIDS

MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 ($

MILLIONS)

FIGURE 22 GLOBAL PRESCRIPTION ANTI-MIGRAINE DRUG

MANUFACTURER MARKET SHARE BY REVENUE, 2008 (%)

FIGURE 23 GLOBAL PRESCRIPTION ANESTHESIA MANUFACTURER

MARKET SHARE BY MANUFACTURER, 2008 (%)

FIGURE 24 GLOBAL PAIN MANAGEMENT DEVICES MARKET BY

PRODUCT TYPE, THROUGH 2013 ($ MILLIONS)

FIGURE 25 GLOBAL NEUROMUSCULAR STIMULATOR/TENS UNIT

MANUFACTURER MARKET SHARE BY MANUFACTURER, 2008 (%)

FIGURE 26 GLOBAL SPINAL CORD STIMULATOR MANUFACTURER

MARKET SHARE, 2008 (%)

FIGURE 27 GLOBAL PAIN MANAGEMENT PHARMACEUTICALS AND

DEVICES MARKET BY CATEGORY, 2006-2013 ($ MILLIONS)

FIGURE 28 PERCENT DISTRIBUTION OF THE WORLDWIDE PAIN

MANAGEMENT MARKET BY SEGMENT, 2008 (%)

Abstract

• The global market for pain management pharmaceuticals and devices amounted to $19.1 billion in 2008 and is expected to increase to $32.8 billion in 2013. The compound annual growth rate (CAGR) for the 5-year period is projected at 11.5%.
• The pharmaceuticals segment dominated the market at $17.6 billion in 2008. That figure is expected to increase to $30.2 billion in 2013, for a CAGR of 11.5%.
• The devices segment of the market generated $1.48 billion in sales in 2008 and is projected to increase to $2.5 billion in 2013, for a CAGR of 11.4%.

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