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Published by: Takeda Pacific
Published: Sep. 1, 2006 - 161 Pages
Table of Contents
- 1. Introduction
- About This Report
- Overview
- Drug Delivery Systems: Some Definitions
- Drug Delivery Systems: What They Can Do
- Highlights of Pharma Issues Driving the Need for Drug Delivery
- Declining Pharmaceutical Industry Productivity
- Patent Expirations and Declining Branded Drug Sales
- Pharmas Use Patent Extension Strategies
- Many Pharmas Will Seek Partners for Drug Delivery
- New Crop of Drugs Will Reach the Market in Near Term
- Limited Pharma Resources: Its Difficult to Invent New Drugs
- Every Drug Needs a Drug Delivery System
- Key Motivators for Developing Drug Delivery Systems
- Business Considerations
- Genomics, Proteomics and Targeted Therapies
- Protein and Peptide Drugs
- Expanding Knowledge About Disease Mechanisms
- Commercial and Technical Challenges of Drug Delivery Companies
- Market is Diverse and Dynamic
- An Expanding Industry
- Companies Migrating to Become Specialty or Generic Pharmas
- Business Trends
- A Market Snapshot
- The Pharma Industry Wants Drug Delivery Systems
- Changing Business Models
- 2. Drug Delivery Technology Developments
- Delivery by Controlled Release Approaches
- Oral Drug Delivery
- New Formulations and Packaging
- Chewable Tablets
- Orally Disintegrating Tablets (ODTs)
- Orally Disintegrating Film Strips (ODFs)
- Enhancing Drug Bioavailability or Solubility
- Injection Drug Delivery
- Needle-free Injection
- Drug Delivery by Implantable Infusion Pump
- Intraosseous Injection
- Drug Delivery to Specific Organs
- Lung Drug Delivery
- Drug Delivery via the Nose
- Delivery to the Cardiovascular System
- Delivery to the Gastrointestinal Tract
- Delivery to the Urogenital Tract
- Drug Delivery into the Eye
- Drug Delivery by Transdermal Methods
- Drug Delivery to Mucosal Membranes
- Targeting Selected Disease Sites
- Drug Delivery by Polymers and Proteins
- Drug Delivery by Small Particles
- Monoclonal Antibodies
- Drug Delivery by Liposomes
- Drug Delivery by Heat-Activated Liposomes
- Drug Delivery by Microparticles
- Drug Delivery by Modified Blood Cells
- Drug Delivery by Nanoparticles
- Viral Vectors for Gene Delivery
- Non-Viral Vectors for Gene Delivery
- 3. Survey of Changing DDS Developments
- Inhalation System
- Polymer Development
- Protein Drug Delivery
- Therapeutic MAbs
- Developments in Polyethylene Glycol (PEG)
- Vaccines
- Nanotech
- Buccal Development
- Drug Delivery to the Eye
- Analyst Opinion: Next Generation Companies
- 4. Recent Strategic Alliances and M&As
- Alliance Analysis: Deals Through 2006
- Summaries of Drug Delivery Alliance Deals
- 5. Drug Delivery Systems Market Forecast
- The US Drug Delivery Market
- A Large Market
- New Innovations Help Drugs Work Better
- Demand for Less Invasive Drugs and Treatments
- Pharmaceutical Firms Can Differentiate Products
- The US Drug Delivery Market, 2005-2010E
- Market Segments Defined by Route of Administration
- Oral Delivery Segment
- Injectable Delivery Segment
- Injection Devices Delivery Segment
- Inhaled Delivery Segment
- Inhaler Devices Segment
- Transdermal Delivery Segment
- Implant Delivery Segment
- Transmucosal Delivery Segment
- Therapeutic Antibodies Segment
- Therapeutic & Cancer Vaccine Segment
- Targeted Therapy/Delivery Segment
- Other Delivery Segment
- Market Shares of the US Drug Delivery Market, 2005 and 2010
- Market Map: DDS Companies by Technology Categories
- 6. Patent Litigation Examples
- University of Alabama v. Nektar Therapeutics
- IVAX, Teva Pharmaceutical Industries Ltd. , et al v.
- Eli Lilly
- Johnson & Johnson v. Boston Scientific
- Chiron Corporation v. Corus Pharma, Inc.
- Novartis Pharmaceuticals Corp. , et al v. Sun
- Pharmaceutical Industries Ltd.
- GlaxoSmithKline Plc v. Par Pharmaceutical Companies,
- Inc. (Kali Laboratories, Inc. )
- Santarus, Inc. v. TAP Pharmaceutical Products, Inc.
- Travanti Pharma Inc. v. IOMED
- 7. Drug Delivery With Nanotechnology
- Nanotechnology
- Companies Using Nanotechnology for Drug Delivery
- Commercializing Nanotechnology
- Selected Nanotech R&D Companies
- Activities of Selected Drug Delivery Companies
- Abgenix, Inc. (Amgen)
- Alkermes, Inc.
- Alnylam Pharmaceuticals, Inc.
- Antigenics, Inc.
- Aradigm Corporation
- Cima Laboratories (Cephalon)
- Elan Corporation
- Intradigm Corporation
- Medarex, Inc.
- NanoBio Corporation
- NanoMed Pharmaceuticals, Inc.
- Nastech Pharmaceutical Company, Inc.
- Nektar Therapeutics
- Nexmed, Inc.
- Noven Pharmaceuticals, Inc.
- Palatin Technologies, Inc.
- Raven Biotechnologies, Inc.
- Sanofi Pasteur SA (Vaccines)
- Sirna Therapeutics, Inc.
- Skyepharma PLC
- Sontra Medical Corporation
- Watson Pharmaceuticals, Inc.
- Wyeth
- 8. Appendices
- Appendix A: Top Drug Delivery Companies
- Appendix B: Drug Delivery Industry Websites
- Pharmaceutical Industry Sites
- Government Office Sites
- Industry News Sites
- Appendix C: Glossary of Terms
- About the Publisher and Authors
- About Takeda Pacific
- About the Authors
- List of Tables
- Table 1. Drug Delivery Systems Market in US, 2005-2010
- Table 2. Survey Results: Emerging Drug Delivery Technologies
- Table 3. Previous Survey Results: Top New DDS Technologies (2004)
- Table 4. DDS Technology Review
- Table 5. Strategic Alliance and M&A Analysis, 2004 through Mid-2006
- Table 6. Alliances in 2006
- Table 7. Alliances in 2005
- Table 8. Alliances in 2004
- Table 9. Drug Delivery Market in the US by Segments, 2005- 2010E
- Table 10. US DDS Market Revenues by Share, 2005 and 2010E
- Table 11. Competing DDS Companies by Technology Categories
- Table 12. Examples of Drug Delivery Litigations
- Table 13. Drug Delivery Companies Using Nanotechnology
- Table 14. The Top Drug Delivery Companies by Total Revenues (2005)
- List of Illustrations
- Figure 1. Drug Delivery Systems Market in the US, 2005-2010
- Figure 2. Controlled Release Drug Delivery System
- Figure 3. The Oral Drug Delivery Route
- Figure 4. Products Featuring Orally Disintegrating Film Strips
- Figure 5. Injection Drug Delivery by Needle Size
- Figure 6. Implantable Insulin Delivery System
- Figure 7. Inserting a Needle for Bone Marrow Infusion
- Figure 8. Airway Delivery by Nektar
- Figure 9. Close-up of Drug Delivery Mechanism to the Lung
- Figure 10. Two Leading Drug-Coated Stents
- Figure 11. Urogenital Drug Delivery For Men
- Figure 12. Drug Delivery Mechanism for a Transdermal Patch
- Figure 13. The DOT Matrix Patch by Noven
- Figure 14. Drug Delivery Market in the US by Segments, 2005-2010E
- Figure 15. US DDS Market Revenues by Share, 2005 and 2010E
AbstractThis research study is about drug delivery systems. It provides readers with relevant information, insights and analysis. This important medical opportunity is assessed in terms of technical and business areas. The participating companies are mapped to show where they fit in the industry landscape. This study reviews the kinds of drug delivery systems that are being used by pharma, biotech or medical device companies.
The report discusses the broad range of drug delivery systems, the technical advances and the applications that drug makers might use. Key advances include orally dissolving tablets and film strips, needle- and needle-free injection systems, transdermal patches, transmucosal delivery, RNAi, drug-coated stents, PEG, nanotechnology, liposomes, monoclonal antibodies, gene delivery, and implants, which all contribute to the many ways that drugs or therapies can be delivered. Drug delivery systems are reviewed in terms of approaches used for delivering drugs targeting major diseases including cardiovascular, cancer, asthma, diabetes, and the central nervous system among others.
This market study shows that drug delivery technologies can help drug makers overcome some of their big challenges. The drug industry continues to see the commercial demise of major branded drugs that reach their patent expiration date. Billions of dollars in revenues are lost to generic drug makers each year. The technology can be used as part of a ‘line extension’ strategy to extend the commercial life of their profitable products. Drug delivery can help ‘rescue’ drug projects with technical challenges by using a customized delivery system.
This report discusses the above topics with interesting and useful findings. The study estimates that the US drug delivery market value might reach nearly $85 billion by 2010. The research includes over 235 key alliances and M&As through 2006. This study uses 29 figures and tables to illustrate the findings or trends. The profiles about companies important to the expanding drug delivery market include detailed information about their business and technical activities.
This report would benefit people with job titles including CEO, VPs, Director of Business Development, Research Directors, Entrepreneurs, Venture Capitalists, Investment Planners, Research Scientists, Consultants or Industry Analysts.
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