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Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies)

Drug delivery is evolving at a rapid rate with new drug product formulations being discovered frequently. Advanced drug delivery deals with developing solutions for new entities in therapeutic pharmacology such as protein and peptides and other novel compounds targeting drugs to specific disease sites including gene therapy. Treatments for chronic conditions and growth in patient-administered drugs are factors leading to greater focus on ease-of-use and convenience.

Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies) details the types of drug delivery systems, technologies and products utilizing advanced drug delivery systems The report describes the industry, its relationship to various healthcare channels, and the trends for the future.

The advanced drug delivery market is two-fold. First of all it identifies drug delivery technology Secondly, it identifies products in the pharmaceutical arena that utilize those drug delivery technologies. Because drug delivery technology is an integral part of sales of pharmaceuticals and drug delivery technology cannot exist without pharmaceuticals, revenues have been reported that include pharmaceutical sales. This report will provide market data that includes the pharmaceutical revenues of those products that utilize advanced drug delivery.

In this report, the advanced drug delivery market is divided into three main segments and market estimates are provided for indications within each category:

  • Liposome Drug Delivery (by Indication - Fungal Infections Cancer, Others)

  • Polymer Drug Delivery (by Indication - Cancer, Neutropenia, Hepatitis, Contraception, Schizophrenia, Acromegaly and Others)

  • Monoclonal Antibodies Drug Delivery (by Indication - Arthritis, Cancer, Multiple Sclerosis, Macular Degeneration, Respiratory Syncytial Virus, Others)

The following types of polymer delivery drugs are segmented within this report.

  • PEGylated Delivery
  • Emulsuion Delivery
  • Injectable Delivery
  • Nanoparticle Delivery
  • Others
A wide range of trends and issues that will impact the advance drug delivery market are discussed in the report including the current state of biotechnolgy expansion, molecular imprinted polymers, hot-melt extrusion, metallofullerenes, nanotechnology advancements and other emerging Drug Delivery technologies not yet on the market.

The following companies are profiled in the report:

  • Alkermes, Inc.
  • ALZA Corporation
  • AP Pharma
  • Centocor Ortho Biotech, Inc.
  • Eisai , Inc
  • Elan Corporation, Plc
  • EnColl Corporation, Inc.
  • Enzon Pharmaceuticals, Inc
  • Gilead Sciences, Inc.
  • Nektar Therapeutics
  • PDL BioPharma
  • pSivida Corp
  • SurModics, Inc
  • Tolmar, Inc
The research conducted by Kalorama Information included comprehensive research of primary and secondary sources such as interviews with company executives, company literature, databases, investment reports, and medical and business journals. New technologies, market developments, and research and development trends and expenditures were identified through patent and data-based searches, as well as via interviews with key personnel. Person-to-person and telephone interviews were the primary method of gathering information. E-mail correspondence was also used in the interview process. Interviews with 24 key industry officials, trade association spokespersons, consultants, healthcare providers, and government personnel were compiled to form the primary basis of information - particularly revenue and market share data- presented in this report.

All market data pertains to the worldwide market at the manufacturers’ level and was measured in U.S. dollars. The base year for data was 2010. Historical data are provided for 2006 through 2009, with forecast data provided for 2010 through 2014. Compound annual growth rates (CAGR) are provided for the 2006-2010, 2010-2014 and 2006-2014.

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For Kalorama's take on the healthcare news of the week, based on our analysis of healthcare markets, follow Kalorama Information's Key Point Blog at http://kaloramakeypoint.blogspot.com/


Nanotechnology Revolutionizing Drug Delivery Methods: Kalorama

Growth in biological drugs and gene therapy is driving developments in the advanced drug delivery market. A report from healthcare market research publisher Kalorama Information, Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies), finds that nanotechnology is the most promising area in the $60.6 billion global market for advanced drug delivery products.

Advanced drug delivery strategies are taking advantage of new entities in therapeutic pharmacology, such as proteins and peptides and other novel compounds that target drugs to specific disease sites. For Example, gene therapy has shown promise, but its development is stymied by the lack of appropriate delivery methods.

"The goal of advanced drug delivery systems is to deploy medications intact to specifically targeted parts of the body through a medium that can control the therapy's administration by means of a physiological chemical trigger," said Melissa Elder, an analyst for Kalorama Information and the author of the study. "To achieve this goal, researchers are turning to advances in micro and nanotechnology."

During the last decade, polymeric microspheres, polymer micelles, and hydrogel-type nanocarriers have all been shown to be effective in enhancing drug targeting specificity, lowering drug toxicity, improving treatment absorption rates, and providing protection for drugs against biochemical degradation.

"Some areas of nanotechnology are more advanced than others," said Elder. "However, all are playing a large role in diagnostics, pharmaceuticals and therapeutics."

Kalorama finds sales in nanomedicine are expected to spike with the highly anticipated development of monoclonal antibodies for respiratory indications, psoriasis, prevention of transplant rejection and cancer. Over twenty companies have patents in this area of development, indicating a propitious future outlook. With an increasing number of disease and cancer patients, pharmaceutical companies are facing a difficult challenge in the delivery of breakthrough medications. There is an immense revenue opportunity in nanotechnology capable of providing targeted drug delivery.

Advanced Drug Delivery Markets (Liposomes, Polymers and Monoclonal Antibodies) analyzes several trends, including molecular imprinted polymers, antibiotic biodegradable implants, hot-melt extrusion technology, sorbent technology, and gene therapy drug delivery. The report concentrates on liposome and polymer drug delivery, as well as monoclonal antibodies.

  • Executive Summary
    • OVERVIEW
    • MARKET DRIVERS
    • MARKET SIZE AND GROWTH
      • Table The Global Market for Advanced Drug Delivery 2006-2014
    • MARKET TRENDS
  • Introduction and Overview
    • INTRODUCTION
    • SCOPE AND METHODOLOGY
    • REASONS FOR ADVANCED DRUG DELIVERY SYSTEMS
    • PHASES OF DRUG ACTION
      • Table Sequence of Drug Action
  • Liposome Drug Delivery
    • OVERVIEW
    • LIPOSOME TARGETING
      • Passive Targeting
      • Active Targeting
        • Table Marketed Liposome Drugs, as of October 2010
    • NEW DEVELOPMENTS
      • Table New Developments in Liposome Drugs
    • MARKET SUMMARY
      • Table The Global Market for Liposomes 2006-2014
      • Liposome Market by Indication
        • Table The Global Market for Liposomes by Indication, 2006-2010
      • Liposome Market Competitive Analysis
        • Table Advanced Drug Delivery: Liposome Market-Competitors Revenues and Market Shares 2009
  • Polymer Drug Delivery
    • OVERVIEW
    • POLYMERIC IMPLANTS
    • BIODEGRADABLE POLYMERS
      • Table Marketed Biodegradable Polymer Drugs, as of October 2010
    • NANO- AND MICROPARTICULATES
      • Table Marketed Nano- and Micro-particle Drugs, as of October 2010
    • POLYMER MICELLES
    • PEGYLATION TECHNOLOGY
      • Table Marketed PEGylated Drugs, as of October 2010
    • HYDROGEL POLYMERS
      • Table Marketed Hydrogel Polymer Drugs, as of October 2010
    • COLLOIDAL SYSTEMS
      • PLA, PLG, and PLGA
      • Emulsions
        • Table Marketed Emulsions, as of October 2010
      • Proteinaceous microparticles
    • NEW DEVELOPMENTS
      • Table New Developments in Polymers
    • MARKET SUMMARY
      • Table The Global Market for Polymers 2006-2014
      • Market for Polymers by Product Type
        • Table Market for Polymers by Product Type 2006-2014
      • Polymer Market by Indication
        • Table The Global Market for Polymers by Indication, 2006-2010 (in millions of dollars at the manufacturers' level)
      • Polymer Market Competitive Analysis
        • Table Advanced Drug Delivery: Polymer Market-Competitors Revenues and Market Shares 2009
  • Monoclonal Antibody Drug Delivery
    • OVERVIEW
      • Table Key Marketed Monoclonal Antibodies, as of October 2010
    • NEW DEVELOPMENTS
      • Table New Developments in Monoclonal Antibodies
    • MARKET SUMMARY
      • Table The Global Market for Monoclonal Antibodies 2006-2014
      • Monoclonal Antibody Market by Indication
        • Table The Global Market for Monoclonal Antibodies by Indication, 2006-2010
      • Monoclonal Antibody Market Competitive Analysis
        • Table Advanced Drug Delivery: Monoclonal Antibody Market- Competitors Revenues and Market Shares 2009
  • Trends and Technology Developments
    • EXPANSION OF BIOTECHNOLOGY
    • INCORPORATION OF TECHNOLOGY
    • MOLECULAR IMPRINTED POLYMERS
    • ANTIBIOTIC BIODEGRADABLE IMPLANTS
    • HOT-MELT EXTRUSION TECHNOLOGY
    • SORBENT TECHNOLOGY
    • GENE THERAPY DRUG DELIVERY
    • METALLOFULLERENES
    • ANTISENSE DELIVERY SYSTEMS
    • NANOTECHNOLOGY ADVANCEMENTS
      • Table Nanotechnology Drug Delivery 2010, Companies and Technology
    • CAMOUFLAGED NANOPARTICLES
    • TRIGGERABLE DRUG DELIVERY
    • PRODRUG DRUG DELIVERY
    • SINGLE CHAIN ANTIGEN-BINDING PROTEIN TECHNOLOGY
    • HEAT SHOCK PROTEIN TECHNOLOGY
    • OTHER EMERGING DRUG DELIVERY TECHNOLOGIES
  • Market Size and Growth
    • TOTAL MARKET SUMMARY
      • Table The Worldwide Market for Advanced Drug Delivery Systems Revenues by Type 2006-2014
      • Table The Worldwide Market for Advanced Drug Delivery Systems Market Share by Type 2006-2014
    • GEOGRAPHICAL MARKET SUMMARY
      • Table Worldwide Advanced Drug Delivery by Geographical Region, 2006-2010 (in billions of dollars at the manufacturers' level)
      • Table Worldwide Market for Advanced Drug Delivery System Revenues and Market Share by Supplier 2009
    • COMPETITIVE GROWTH ANALYSIS
  • Company Profiles
    • ALKERMES, INC.
    • ALZACORPORATION
    • APPHARMA
    • CENTOCOR ORTHO BIOTECH, INC.
    • EISAI , INC
    • ELAN CORPORATION, PLC
    • ENCOLL CORPORATION, INC.
    • ENZON PHARMACEUTICALS, INC
    • GILEAD SCIENCES, INC.
    • NEKTAR THERAPEUTICS
    • PDLBIOPHARMA
    • PSIVIDA CORP
    • SURMODICS, INC
    • TOLMAR, INC
  • Company Directory

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