Cancer Immunotherapy Markets
Report Overview:
The technologies and opportunities are explored. Over one hundred companies are profiled. Our research makes you the expert.
A revolution in cancer therapy is underway. New therapy based on using the body’s natural immune defenses is having unprecedented success. This is a complex area but our readable reports help you understand it, both the technology and the opportunity.
The technology is moving faster than the market. Already worth billions the global market is poised for dramatic growth. Is the cure in sight? The impact on the health care industry is enormous. The report forecasts the market size out to 2023.
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CAR – T Cells? Checkpoint Inhibitors? Cytokines? Find out about the technology in readily understood terms that explain the jargon. Find the opportunities and the pitfalls. Understand growth expectations and the ultimate potential market size.
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- 1. Introduction and Market Definition
- 1.1 What is Cancer Immunotherapy?
- 1.2 Immunotherapy – the looming cure
- 1.3 Market Definition
- 1.3.1 Market Size
- 1.3.2 Currency
- 1.3.3 Years
- 1.4 Methodology
- 1.4.1 Authors
- 1.4.2 Sources
- 1.5 U.S. Medical Market and Pharmceutical Spending - Perspective
- 1.5.1 U.S. Expenditures for Pharmaceuticals
- 2. Immunotherapy – Guide to Immune Technologies
- 2.0 The Immune System
- 2.0.1 Innate immune system
- 2.0.1.1 Surface barriers
- 2.0.1.2 Inflammation
- 2.0.1.3 Complement system
- 2.0.1.4 Cellular barriers
- 2.0.1.5 Natural killer cells
- 2.0.2 Adaptive immune system
- 2.0.2.1 Lymphocytes
- 2.0.2.2 Killer T cells
- 2.0.2.3 Helper T cells
- 2.0.2.4 Gamma delta T cells
- 2.0.2.5 B lymphocytes and antibodies
- 2.0.3 Tumor immunology – the immune surveillance system
- 2.1 Immuno Oncology Technologies
- 2.1.1 Monoclonal Antibodies
- 2.1.1.1 Outlook for Monoclonal Antibodies
- 2.1.1.2 Companies with Monoclonal Antibodies in their Pipeline
- 2.1.2 Cancer vaccines
- 2.1.2.1 Outlook for Cancer Vaccines
- 2.1.2.2 Companies with Cancer Vaccines in their Pipeline
- 2.1.3 Cytokines
- 2.1.3.1 Outlook for Cytokines
- 2.1.3.2 Companies with Cytokines in their Pipeline
- 2.1.4 Cell Based Therapies
- 2.1.4.1 Outlook for Cell Based Therapies
- 2.1.4.2 Companies with Cell Based Therapies in their Pipeline
- 2.1.5 Inhibitors/Agonists
- 2.1.5.1 Outlook for Inhibitors/Agonists
- 2.1.5.2 Companies with Inhibitors/Agonists in their Pipeline
- 2.1.6 Antibody Drug Conjugates
- 2.1.6.1 Outlook for Antibody Drug Conjugates
- 2.1.6.2 Companies with Antibody Drug Conjugates in their Pipeline
- 2.1.7 Others
- 2.1.7.1 Outlook for Other Therapeutics
- 2.1.7.2 Companies with Viral Therapeutics in their Pipeline
- 2.1.7.3 Companies with Other Therapeutics in their Pipeline
- 3. Industry Overview
- 3.1 Market Players – Roles & Impacts
- 3.1.1 Drug manufacturers - Larger/pharmaceutical
- 3.1.2 Drug manufacturers - Generic
- 3.1.3 Contract Research and Manufacturing
- 3.1.4 In Vitro Diagnostics Industry
- 3.1.5 Drug Marketing Companies
- 3.1.6 Biotechnology Companies
- 3.1.7 Regulatory Bodies
- 4. Market Trends
- 4.1 Factors Driving Growth
- 4.1.1 Outcome potential
- 4.1.2 Fast tracking
- 4.1.3 Funding
- 4.1.4 Technology Environment
- 4.1.5 Target Solutions
- 4.2 Factors Limiting Growth
- 4.2.1 Cost of Treatment
- 4.2.2 Clinical Trials Role
- 4.2.3 Combinations
- 4.2.4 Protocols
- 4.3 Therapeutic Technology Development
- 4.3.1 Combinations - Issues and Complexity
- 4.3.2 Preference for a drug
- 4.3.3 Problems of Immunity Engineering
- 4.3.4 The Role of Cost
- 4.3.5 The Disruption Dynamic
- 4.3.6 CAR-T Cell Therapy
- 4.3.7 The Next Five Years
- 5. Cancer Immunotherapy Recent Developments
- 5.1 Recent Developments – Importance and How to Use This Section
- 5.1.1 Importance of These Developments
- 5.1.2 How to Use This Section
- Gritstone to Move Slate Immunotherapy into Clinical Trial
- Personalis, Inc. to Provide Tumor Immunogenomic Profiling to the Parker Institute for
- Immunotherapy Biomarker Discovery in Clinical Trial Participants
- Spectrum Announces a Novel Immuno-Oncology Platform including Two Early Stage Assets
- FDA Approves Tecentriq/Chemo for Newly Diagnosed Extensive-stage SCLC
- Keytruda Better Than Chemotherapy
- Cancer ‘vaccine’ eliminates tumors in mice
- Iovance Rides The T-Cell Wave
- Overcoming the Current Limitations of Cancer Immunotherapy
- Startup focused on cell therapy gets acquired
- Positive results in pre-clinical trials for Imugene’s cancer vaccine
- Celsion Corporation OPTIMA Study Continues
- Regeneron and bluebird bio to Collaborate on Cancer Immunotherapy
- Sangamo bulks up in cell therapy with TxCell acquisition
- BI dives deeper into cancer immunotherapy with new acquisition
- Innovest Global Acquires Stake in StemVax Therapeutics
- Eli Lilly Acquires Pegilodecakin, Potential Immunotherapy Now in Phase 3 Trial
- FDA Grants Breakthrough Therapy Designation to Lenvima-Keytruda Combo
- FDA Grants Fast Track Designation to Galinpepimut-S for Treating Multiple Myeloma
- BioLineRx Initiates Phase 1/2a Trial Testing AGI-134 in Metastatic Solid Tumors
- FDA OKs Phase 1 Trial to Test Celyad’s Donor-derived CAR T-cell Therapy in Colorectal
- Cancer
- Vyriad Expands Phase 1 Trial to Test Voyager-V1 in Combination with Bavencio for
- Colorectal Cancer
- FDA Expedites Tecentriq-Avastin Combo for Most Common Liver Cancer
- Immunotherapy Use Can Double Survival Rate of Melanoma Patients with Brain Metastasis
- FDA Grants Priority Review to Keytruda-Chemo Combo for Metastatic NSCLC
- FDA Approves Phase 2 Trial Testing AIVITA’s Vaccine for Aggressive Brain Cancer
- Immunotherapy Candidate M7824 Effective in Advanced Lung Cancer Patients
- Apogenix Prepares Submission for Conditional Marketing Authorization in Europe
- Immunotherapy Leads to Complete Response in Advanced Breast Cancer Patient
- Keytruda Beats Chemo at Increasing NSCLC Patients’ Survival, Phase 3 Trial Shows
- CBT Pharmaceuticals and CrystalGenomics Announce Partnership
- New cancer vaccine against melanoma has 100% success rate
- 6. Profiles of Key Immunotherapy Companies
- 10X Genomics
- A. Menarini
- AbbVie
- Ablynx
- Adaptimmune Therapeutics PLC
- ADC Therapeutics
- Aduro Biotech Inc.
- Agenus Inc.
- AIVITA Biomedical
- Aleta Biotherapeutics
- Amgen
- Antigen Express Inc
- Apeiron Biologics
- Apogenix GmbH
- Aptose Biosciences
- Arcus Biosciences Inc.
- Astrazeneca PLC
- Atara Biotherapeutics
- Atlas Venture
- Aurora Biopharma
- Autolus Therapeutics plc
- Beigene Ltd.
- Bellicum Pharmaceuticals
- BioLineRx
- BioNTech
- Biovest International Inc
- Bluebird bio
- BriaCell Therapeutics
- Bristol-Myers Squibb
- CARsgen Therapeutics
- CBT Pharmaceuticals
- Celgene
- Celldex Therapeutics
- Cellectis S A
- Cellular Biomedicine
- Celsion Corporation
- Celyad
- Chugai Pharmaceutical Co.
- Compugen
- CrystalGenomics
- Cytomx Therapeutics Inc.
- Cytovac A/S
- Daiichi Sankyo
- Dendreon
- Dynavax Technolgy
- Eisai
- Eli Lilly and Co.
- EMD Serono Inc
- eTheRNA
- Fate Therapeutics Inc.
- Five Prime Therapeutics Inc.
- F-star
- Gadeta
- Galectin Therapeutics
- Genentech Inc
- Genmab AS
- Genprex
- Gilead Sciences Inc.
- GlaxoSmithKline
- Gliknik Inc
- GlobeImmune Inc
- Glycostem
- Gritstone Oncology, Inc
- Heat Biologics Inc
- Heidelberg Pharma GmbH
- Idera Pharmaceuticals, Inc
- Immatics Biotechnologies GmbH
- Immudex
- Immune Design
- Immunomedics
- Imugene
- Incyte Corporation
- Inmune Bio Inc.
- Innate Pharma
- Iovance Biotherapeutics Inc.
- iOx Therapeutics
- iTeos Therapeutics
- Janssen Global Services (J&J)
- Jounce Therapeutics
- Juno Therapeutics
- Kite Pharma Inc
- KSQ Therapeutics
- Life Science Pharmaceuticals
- MabVax Therapeutics Holdings Inc
- Macrogenics Inc.
- MedImmune LLC
- Merck & Co., Inc
- Mirati Therapeutics
- Moderna Therapeutics
- Morphosys AG
- Morphotek Inc
- Myriad RBM
- Mustang Bio
- Nanjing Legend Biotech
- Nantkwest
- NBE Therapeutics
- Nekonal Oncology
- Nektar Therapeutics
- Neon Therapeutics
- NewLink Genetics Corp
- Nilogen
- Noile-Immune Biotech
- Northwest Biotherapeutics Inc
- Novartis A G
- Novelogics Biotechnology, Inc.
- Novo Nordisk
- OncoPep Inc
- OSE Immunotherapeutics
- Oxford BioTherapeutics Ltd
- Personalis
- Pfizer
- Pieris Pharmaceuticals
- Pique Therapeutics
- Progenics
- PsiOxus
- Qiagen
- Recepta Biopharma
- Regen Biopharma Inc
- Regeneron Pharmaceuticals
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