KOL Perspectives: IL-6 inhibitors in Rheumatoid Arthritis

KOL Perspectives: IL-6 inhibitors in Rheumatoid Arthritis


This KOL Insight briefing focuses on perceptions of IL-6 inhibitors in rheumatoid arthritis (RA).

The briefing includes analysis of KOL opinion on the following topic areas -

  • Current or anticipated future use of sarilumab in RA
  • Current use of tocilizumab in RA
  • Expected future change to sarilumab & tocilizumab use
  • Comparison of sarilumab & tocilizumab clinical profile in RA
  • Non-clinical differentiating factors between sarilumab & tocilizumab
  • Impact of and factors contributing to sirukumab discontinuation in RA
  • IL-6 inhibitors vs. JAK inhibitors in RA
  • KOL awareness of olokizumab currently in development for RA
Key Highlights
  • Majority of US but not EU patients have access to sarilumab, with KOLs primarily positioning sarilumab in MTX-IR patients or after anti-TNFs
  • Most KOLs position tocilizumab after anti-TNFs, partly due to payer pressure, with first-line use possible in MTX-IR or ineligible patients
  • In the next 12 months, most KOLs expect an increase in use of sarilumab, and a reduction in use of tocilizumab.
  • The briefing is based on Sociable Pharma’s analysis of primary research with our RA key opinion leaders (KOLs)
  • In total, we conducted interviews with 10 KOLs: Five Europe-based & five US-based
  • Interviews performed in December 2017
  • KOL data is analyzed to produce: Charts summarizing KOL opinions
  • Chart call-outs of key information & details
  • KOL quotes
  • Summary of KOL reporting trends
  • Insight from Sociable Pharma's analysts.
Reasons to buy
  • Combines Qualitative & semi-quantitative insight from key opinion leaders on IL-6 inhibitors in Rheumatoid Arthritis
  • Includes insight & recommendations from our disease-specific healthcare analysts
  • Utilizes independent expert viewpoints to validate the impact of new clinical data & emerging trends on management of rheumatoid arthritis
  • Provides cost-effective support for your advisory boards, with topics acting as a catalyst for further expert discussion.

Executive Summary
Research Panel Composition
Results & Implications

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