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Opioid-Induced Constipation (OIC) - Pipeline Review, H2 2015

Opioid-Induced Constipation (OIC) - Pipeline Review, H2 2015

Summary

Global Markets Direct’s, ‘Opioid-Induced Constipation (OIC) - Pipeline Review, H2 2015’, provides an overview of the Opioid-Induced Constipation (OIC)’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Opioid-Induced Constipation (OIC), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Opioid-Induced Constipation (OIC) and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

  • The report provides a snapshot of the global therapeutic landscape of Opioid-Induced Constipation (OIC)
  • The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in the therapeutics development for Opioid-Induced Constipation (OIC) and enlists all their major and minor projects
  • The report summarizes all the dormant and discontinued pipeline projects
  • A review of the Opioid-Induced Constipation (OIC) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • A detailed assessment of monotherapy and combination therapy pipeline projects
  • Coverage of the Opioid-Induced Constipation (OIC) pipeline on the basis of target, MoA, route of administration and molecule type
  • Latest news and deals relating related to pipeline products
Reasons to buy
  • Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Identify and understand important and diverse types of therapeutics under development for Opioid-Induced Constipation (OIC)
  • Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
  • Devise corrective measures for pipeline projects by understanding Opioid-Induced Constipation (OIC) pipeline depth and focus of Indication therapeutics
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
  • Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline


Introduction
Global Markets Direct Report Coverage
Opioid-Induced Constipation (OIC) Overview
Therapeutics Development
Pipeline Products for Opioid-Induced Constipation (OIC) - Overview
Opioid-Induced Constipation (OIC) - Therapeutics under Development by Companies
Opioid-Induced Constipation (OIC) - Pipeline Products Glance
Late Stage Products
Clinical Stage Products
Opioid-Induced Constipation (OIC) - Products under Development by Companies
Opioid-Induced Constipation (OIC) - Companies Involved in Therapeutics Development
AstraZeneca Plc
Cosmo Pharmaceuticals S.p.A
Ironwood Pharmaceuticals, Inc.
Shionogi & Co., Ltd.
Sucampo Pharmaceuticals, Inc.
Synergy Pharmaceuticals, Inc.
Valeant Pharmaceuticals International, Inc.
Opioid-Induced Constipation (OIC) - Therapeutics Assessment
Assessment by Monotherapy Products
Assessment by Combination Products
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Drug Profiles
(axelopran sulfate + oxycodone hydrochloride) - Drug Profile
Product Description
Mechanism of Action
R&D Progress
axelopran sulfate - Drug Profile
Product Description
Mechanism of Action
R&D Progress
dolcanatide - Drug Profile
Product Description
Mechanism of Action
R&D Progress
linaclotide - Drug Profile
Product Description
Mechanism of Action
R&D Progress
lubiprostone - Drug Profile
Product Description
Mechanism of Action
R&D Progress
methylnaltrexone bromide - Drug Profile
Product Description
Mechanism of Action
R&D Progress
naldemedine - Drug Profile
Product Description
Mechanism of Action
R&D Progress
naloxegol oxalate - Drug Profile
Product Description
Mechanism of Action
R&D Progress
naloxone hydrochloride - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Opioid-Induced Constipation (OIC) - Recent Pipeline Updates
Opioid-Induced Constipation (OIC) - Dormant Projects
Opioid-Induced Constipation (OIC) - Discontinued Products
Opioid-Induced Constipation (OIC) - Product Development Milestones
Featured News & Press Releases
Aug 03, 2015: Naldemedine Meets Primary Endpoint In Phase 3 Study For The Treatment Of Opioid-Induced Constipation
Jun 24, 2015: Shionogi Announces That Naldemedine Met the Primary Endpoint in Its First Japanese Phase 3 Study for the Treatment of Opioid - Induced Constipation in Cancer Patients
Jun 03, 2015: RELISTOR Receives European Approval for Expanded Indication to Treat All Opioid-Induced Constipation
May 19, 2015: Phase IIb Data Show Once-Daily Naldemedine Provides Significant Improvement For Patients With Opioid-Induced Constipation
May 16, 2015: MOVANTIK (naloxegol) Safety Analyses of Opioid-Induced Constipation Patients 65 and Older with Chronic Non-Cancer Pain
May 15, 2015: Sucampo Announces Clinical Data on Lubiprostone to be Presented at Digestive Disease Week
Apr 24, 2015: RELISTOR Receives Positive CHMP Opinion in the EU for the Treatment of Opioid-Induced Constipation in Adults with Chronic Non-Cancer Pain
Apr 02, 2015: Nektar Announces Receipt of $100 Million Milestone Payment from AstraZeneca
Mar 31, 2015: MOVANTIK (Naloxegol) Tablets For The Treatment Of Opioid-Induced Constipation In Adult Patients With Chronic Non-Cancer Pain Launched In The US
Mar 30, 2015: Shionogi Announces That Naldemedine Meets Primary Endpoint In A Phase 3 Study For The Treatment Of Opioid-Induced Constipation
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Number of Products under Development for Opioid-Induced Constipation (OIC), H2 2015
Number of Products under Development by Companies, H2 2015
Comparative Analysis by Late Stage Development, H2 2015
Comparative Analysis by Clinical Stage Development, H2 2015
Products under Development by Companies, H2 2015
Opioid-Induced Constipation (OIC) - Pipeline by AstraZeneca Plc, H2 2015
Opioid-Induced Constipation (OIC) - Pipeline by Cosmo Pharmaceuticals S.p.A, H2 2015
Opioid-Induced Constipation (OIC) - Pipeline by Ironwood Pharmaceuticals, Inc., H2 2015
Opioid-Induced Constipation (OIC) - Pipeline by Shionogi & Co., Ltd., H2 2015
Opioid-Induced Constipation (OIC) - Pipeline by Sucampo Pharmaceuticals, Inc., H2 2015
Opioid-Induced Constipation (OIC) - Pipeline by Synergy Pharmaceuticals, Inc., H2 2015
Opioid-Induced Constipation (OIC) - Pipeline by Valeant Pharmaceuticals International, Inc., H2 2015
Assessment by Monotherapy Products, H2 2015
Assessment by Combination Products, H2 2015
Number of Products by Stage and Target, H2 2015
Number of Products by Stage and Mechanism of Action, H2 2015
Number of Products by Stage and Route of Administration, H2 2015
Number of Products by Stage and Molecule Type, H2 2015
Opioid-Induced Constipation (OIC) Therapeutics - Recent Pipeline Updates, H2 2015
Opioid-Induced Constipation (OIC) - Dormant Projects, H2 2015
Opioid-Induced Constipation (OIC) - Discontinued Products, H2 2015
List of Figures
Number of Products under Development for Opioid-Induced Constipation (OIC), H2 2015
Number of Products under Development by Companies, H2 2015
Comparative Analysis by Late Stage Development, H2 2015
Comparative Analysis by Clinical Stage Development, H2 2015
Assessment by Monotherapy Products, H2 2015
Number of Products by Top 10 Targets, H2 2015
Number of Products by Stage and Top 10 Targets, H2 2015
Number of Products by Top 10 Mechanism of Actions, H2 2015
Number of Products by Stage and Top 10 Mechanism of Actions, H2 2015
Number of Products by Top 10 Routes of Administration, H2 2015
Number of Products by Stage and Top 10 Routes of Administration, H2 2015
Number of Products by Top 10 Molecule Types, H2 2015
Number of Products by Stage and Top 10 Molecule Types, H2 2015

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