Lambert-Eaton Myasthenic Syndrome (LEMS) - Market Insights, Epidemiology, and Market Forecast-2030

DelveInsight’s ‘Lambert–Eaton Myasthenic Syndrome (LEMS)—Market Insights, Epidemiology, and Market Forecast–2030’ report deliver an in-depth understanding of the LEMS, historical and forecasted epidemiology as well as the LEMS market trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan.
The LEMS market report provides current treatment practices, emerging drugs, and market share of the individual therapies, current and forecasted 7MM LEMS market size from 2017 to 2030. The Report also covers current LEMS treatment practice/algorithm, market drivers, market barriers, SWOT analysis, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.
Geography Covered
• The United States
• EU5 (Germany, France, Italy, Spain, and the United Kingdom)
• Japan

Study Period: 2017–2030
Lambert–Eaton Myasthenic Syndrome (LEMS) Disease Understanding and Treatment Algorithm
Lambert–Eaton Myasthenic Syndrome (LEMS) Overview
Lambert–Eaton myasthenic syndrome (LEMS) is an autoimmune disease in which the immune system attacks the body's own tissues. The attack occurs at the connection between nerve and muscle (the neuromuscular junction) and interferes with the ability of nerve cells to send signals to muscle cells. Specifically, the immune system attacks the calcium channels on nerve endings that are required to trigger the release of chemicals (acetylcholine). With fewer calcium channels, the nerve ending releases less acetylcholine. Acetylcholine is a chemical messenger that triggers muscle contraction. In people with LEMS, the lowered levels of acetylcholine are not sufficient to cause normal muscle contractions, causing muscle weakness. The disease is named for Edward Lambert and Lee Eaton, neurologists at the Mayo Clinic in Rochester, Minn., who first described the myasthenic syndrome in the 1950s and 1960s.
There are two types of LEMS, paraneoplastic, in which the disease is associated with cancer and non-paraneoplastic with no known underlying cause.
Lambert–Eaton Myasthenic Syndrome (LEMS) Diagnosis
The presence of clinical features such as proximal muscle weakness associated with areflexia and autonomic dysfunction should prompt an evaluation for LEMS. The diagnosis of LEMS is often difficult if the disease is not suspected since weakness in the legs with or without arm weakness and fatigue are common complaints in general. The diagnosis is more likely to be suspected in people with cancer. Often, the initial suspected diagnosis is myasthenia gravis (MG), due to an overlap in symptoms. The presence of a dry mouth is also a helpful clue. The diagnosis of LEMS can be confirmed by the presence of antibodies against P/Q-type voltage-gated calcium channels (VGCC) along with electrodiagnostic studies.
If a diagnosis of LEMS is confirmed, a CT scan of the is obtained to look for a small cell lung cancer. If negative, a PET-CT is considered. If negative, follow-up chest CTs are recommended for up to 5 years to monitor for underlying cancer. A 2010 taskforce recommended repeating this screening at three to six months, and then every six months for two years in people with LEMS, if testing remains unrevealing. Most cancers, if present, are detected in the first year.
Continued in the report…..
Lambert–Eaton Myasthenic Syndrome (LEMS) Treatment
There is no cure for LEMS, as scientists have not yet figured out how to selectively stop the autoimmune attack on motor nerve terminal calcium channels and other nerve terminal proteins targeted by LEMS. Therefore, symptomatic treatments for neuromuscular weakness that results from LEMS are favored. Medications and therapies that may be used to treat LEMS include 3, 4-diaminopyridine (enhances acetylcholine release), anticholinesterase agents (e.g., pyridostigmine), plasma exchange, intravenous immunoglobulins (IVIG), and medications that suppress the immune system (e.g., prednisone, azathioprine).
Lambert–Eaton Myasthenic Syndrome (LEMS) Epidemiology
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Total Prevalent Cases of LEMS, Total Diagnosed Prevalent Cases of LEMS, Gender-specific Diagnosed Prevalent Cases of LEMS, Type-specific Diagnosed Prevalent Cases of LEMS, and Diagnosed Prevalent Cases of LEMS by Malignancy scenario of LEMS in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom) and Japan from 2017 to 2030.
Key Findings
• Total prevalent cases of LEMS in the 7MM was found to be 5,977 in 2017.
• Based on the etiology, LEMS is divided into two types; paraneoplastic and idiopathic. There were a total 1,978 diagnosed prevalent cases of LEMS in the United States in 2017, out of which 1,154 accounted for paraneoplastic and 824 cases accounted for idiopathic.
• As per the assessments, in the 7MM, the majority of cases of LEMS are paraneoplastic form as compared to idiopathic form.
• Among the two forms of LEMS, the paraneoplastic form constitutes more than half of the cases and is mostly associated with intrathoracic neoplasms. Most of the cases were seen with small cell lung cancer (SCLC); other subtypes of lung cancer are extremely rare.
• Among the EU-5 countries, Germany witnessed the highest prevalent population accounting for 6.93% of the total prevalent cases in 7MM, followed by France and the United Kingdom. On the other hand, Spain witnessed the lowest number of prevalent cases in 2017.
• Japan was assessed with 21.32% of the total prevalent population, with 1,274 cases observed in 2017.

Lambert–Eaton Myasthenic Syndrome (LEMS) Epidemiology
The epidemiology segment also provides the LEMS epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan.
Lambert–Eaton Myasthenic Syndrome (LEMS) Drug Chapters
The drug chapter segment of the LEMS report encloses the detailed analysis of LEMS marketed drugs, mid-phase, and late-stage pipeline drugs. It also helps to understand the LEMS clinical trial details, expressive pharmacological action, agreements and collaborations, approval, and patent details of each included drug and the latest news and press releases.
Lambert–Eaton Myasthenic Syndrome (LEMS) Marketed Drugs
Firdapse: Catalyst Pharmaceutical
Firdapse (amifampridine) is a potassium channel blocker used to treat LEMS in adults. The active ingredient of Firdapse is amifampridine phosphate, which is a voltage-gated potassium channel blocker. Amifampridine phosphate is described chemically as 3, 4-diaminopyridine phosphate. Each Firdapse tablet contains 10 mg amifampridine (equivalent to 18.98 mg amifampridine phosphate). The drug was developed by BioMarin Pharmaceutical and is marketed by Catalyst Pharmaceutical, which secured the marketing rights to Firdapse in North America.
In June 2019, Catalyst Pharmaceutical filed a lawsuit against the US FDA over the regulatory agency’s decision to approve a rival treatment for its newly-approved LEMS. Documents released in court, including partially redacted emails from the FDA, appear to show that issues regarding the list price for Firdapse (amifampridine). The lawsuit alleges that the approval of Ruzurgi, a rival drug from privately held Jacobus Pharmaceutical Co, in May 2019, violated provisions of FDA regulations and Catalyst’s rights to exclusivity for its drug, Firdapse.
Catalyst recently announced plans to expand sales to Japan. They recently had talks with the Japanese Ministry of Health, Labor and Social Affairs (MHLW) to get Firdapse approved in Japan.
Products detail in the report…
Ruzurgi: Jacobus Pharmaceutical Company Inc.
Ruzurgi (amifampridine) is a potassium channel blocker indicated for the treatment of LEMS in patients 6 years to less than 17 years of age. It is supplied as a tablet for oral administration. Ruzurgi is designed to prolong signals that are released from nerves to allow greater stimulation of the muscle. Ruzurgi works in a similar mechanism to Firdapse (amifampridine phosphate), which was approved in 2018 for the treatment of adults with LEMS. The drug was initially developed as a phosphate salt of amifampridine by Assistance Publique Hôpitaux de Paris. It was later developed and commercialized by various companies, including BioMarin Pharmaceutical, Catalyst Pharmaceuticals, and Jacobus Pharmaceutical.
Products detail in the report…
Lambert–Eaton Myasthenic Syndrome (LEMS) Market Outlook
The therapeutic market of LEMS in the seven major markets was assessed to be USD 59.43 million in 2017 (With Base Case Scenario* and Downside Scenario**) and is expected to grow during the study period (2017–2030).
Currently, there is no cure for LEMS and treatment is mainly symptomatic. This includes 3, 4-diaminopyridine phosphate (DAP), which is usually well-tolerated and effective. In some patients, the combination of pyridostigmine with 3, 4-DAP has been suggested to have an additional positive effect. If symptomatic treatment is insufficient, immunosuppressive therapy with prednisone, alone or in combination with azathioprine, can achieve long-term control of the disorder. Plasmapheresis and high dose administration of intravenous immunoglobulins (IVIGs) have a short effect. An effective treatment against any tumor present is mandatory, both to control the tumor and to improve the clinical symptoms of LEMS.
So far, there are only two FDA approved the medication for LEMS, i.e., Firdapse and Ruzurgi. The FDA’s approval of Firdapse is a potentially transformative milestone in the lives of patients in the US suffering from LEMS, as it now gives adult LEMS patients access to a new first-in-class-therapy. Firdapse is approved in the US and the European Union for use by patients with LEMS.
After the approval of Firdapse, Ruzurgi is the second drug to be approved in the US for the treatment of LEMS and first approved the medication for the treatment of LEMS in patients 6 years to less than 17 years of age. Despite being a potential therapy in the treatment, a lawsuit has been filed by Catalyst Pharma against the US FDA and several related parties challenging the recent approval of an NDA and related drug labeling for Ruzurgi for the treatment of LEMS in pediatric patients. The lawsuit alleges that the approval of Ruzurgi, Catalyst’s rival medicine from privately held Jacobus Pharmaceutical, in May violated provisions of US FDA’s regulations and Catalyst’s rights to exclusivity for its drug, Firdapse. Both drugs are approved to treat LEMS, but Firdapse was approved for adults, while Jacobus’ drug was for children.
Presently there are no approved therapies of LEMS in Japan, Catalyst Pharma announced the plan to expand sales of Firdapse in Japan. They recently had talks with the Japanese Ministry of Health, Labor and Social Affairs (MHLW) to get Firdapse approved in Japan. About two years ago, the Japanese government approved Firdapse as a primary drug for the MHLW and actively asked companies to develop and submit an NDA for the drug. Once Catalyst and MHLW have reached agreement on what will be required to file this NDA in Japan, an update of the approval process for filing an NDA in Japan will be released.
According to DelveInsight, the market size of LEMS in the seven major market (7MM) is expected to change during the study period 2017–2030.
*Base Case Scenario: With the Base Case Scenario, DelveInsight’s analysts estimate that Ruzurgi will not be launch in the market because Catalyst has filed a suit against Jacobus’ drug (Ruzurgi). Therefore, it is estimated that Firdapse will cover a decent market in the upcoming years without any competition
**Downside Scenario: With Downside Scenario, DelveInsight is expecting the launch of Ruzurgi in the United States in the second half of 2020, which will compete and likely to take the market share of Firdapse.
Key Findings
• In 2017, the market size of LEMS in the 7MM was USD 59.43 million.
• Among the 7MM, the United States accounted for the majority of the market size with USD 32.85 million in 2017.
• The current market size of LEMS is entirely dependent on symptomatic treatment regimens, includes Firdapse, 3, 4-diaminopyridine (base), pyridostigmine, immunoglobulin, and others). Others include guanidine, acetylcholinesterase (AChE) inhibitors, prednisone, azathioprine, cyclosporine, and plasmapheresis.
• Firdapse (Catalyst Pharmaceuticals) is the only approved therapy for the treatment of LEMS in adults in the United States and EU5.
• Another Molecule Ruzurgi (Jacobus Pharmaceuticals), is approved by the US FDA in May 2019, for the treatment of patients with LEMS age six to less than 17 years. However, In June 2019, Catalyst filed its lawsuit in the US District Court for the Southern District of Florida and is seeking a reversal of FDA's decision.
• DelveInsight estimates that Japan has the second-highest market size after the United States in 2017, which is accounted for USD 9.59 million.
The United States Market Outlook
This section provides the total LEMS market size and market size by therapies in the United States.
EU-5 Market Outlook
The total LEMS market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom are provided in this section.
Japan Market Outlook
The total LEMS market size and market size by therapies in Japan are provided.
Lambert–Eaton Myasthenic Syndrome (LEMS) Drugs Uptake
This section focusses on the rate of uptake of the potential drugs recently launched in the LEMS market or expected to get launched in the market during the study period 2017–2030. The analysis covers LEMS market uptake by drugs; patient uptake by therapies; and sales of each drug.
This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs based on market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Reimbursement Scenario in Lambert–Eaton Myasthenic Syndrome (LEMS)
Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In the report, we consider reimbursement to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.
Competitive Intelligence Analysis
We perform competitive and market Intelligence analysis of the LEMS market by using various competitive intelligence tools that include–SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies, etc. The inclusion of the analysis entirely depends upon the data availability.
Scope of the Report
• The report covers the descriptive overview of LEMS, explaining its causes, signs and symptoms, risk factors, pathophysiology, pathogenesis, and currently available therapies.
• Comprehensive insight has been provided into the LEMS epidemiology and treatment.
• Additionally, an all-inclusive account of both the current and emerging therapies for LEMS is provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape.
• A detailed review of the LEMS market; historical and forecasted is included in the report, covering the 7MM drug outreach.
• The report provides an edge while developing business strategies, by understanding trends shaping and driving the 7MM LEMS market.
Report Highlights
• The increasing prevalence of the disease will positively drive the LEMS market.
• The companies and academics are working to assess challenges and seek opportunities that could influence LEMS R&D.
• Major players are involved in commercializing therapies for LEMS. Launch of the therapies will significantly impact the LEMS market.
• Our in-depth analysis of the different emerging trends and comparative analysis with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities.
Lambert–Eaton Myasthenic Syndrome (LEMS) Report Insights
• Patient Population
• Therapeutic Approaches
• LEMS Pipeline Analysis
• LEMS Market Size and Trends
• Market Opportunities
• Impact of Upcoming Therapies
Lambert–Eaton Myasthenic Syndrome (LEMS) Report Key Strengths
• 11 Years Forecast
• 7MM Coverage
• LEMS Epidemiology Segmentation
• Key Cross Competition
• Highly Analyzed Market
• Drugs Uptake
Lambert–Eaton Myasthenic Syndrome (LEMS) Report Assessment
• Current Treatment Practices
• Unmet Needs
• Marketed Product Profiles
• Market Drivers and Barriers
• SWOT Analysis
• Market Access and Reimbursement 
Key Questions
Market Insights:
• What was the LEMS market share (%) distribution in 2017 and how it would look like in 2030?
• What would be the LEMS total market size as well as market size by therapies across the 7MM during the forecast period (2020–2030)?
• What are the key findings pertaining to the market across the 7MM and which country will have the largest LEMS market size during the forecast period (2020–2030)?
• At what CAGR, the LEMS market is expected to grow at the 7MM level during the forecast period (2020–2030)?
• What would be the LEMS market outlook across the 7MM during the forecast period (2020–2030)?
• What would be the LEMS market growth till 2030 and what will be the resultant market size in the year 2030?
• How would the market drivers, barriers and future opportunities affect the market dynamics and subsequent analysis of the associated trends?
Epidemiology Insights:
• What is the disease risk, burden and unmet needs of LEMS?
• What is the historical LEMS patient pool in the United States, EU5 (Germany, France, Italy, Spain, and the UK) and Japan?
• What would be the forecasted patient pool of LEMS at the 7MM level?
• What will be the growth opportunities across the 7MM with respect to the patient population pertaining to LEMS?
• Out of the above-mentioned countries, which country would have the highest prevalent population of LEMS during the forecast period (2020–2030)?
• At what CAGR the population is expected to grow across the 7MM during the forecast period (2020–2030)?
Current Treatment Scenario, Marketed Drugs, and Emerging Therapies:
• What are the current options for the treatment of LEMS along with the approved therapy?
• What are the current treatment guidelines for the treatment of LEMS in the US, Europe and Japan?
• What are the LEMS marketed drugs and their MOA, regulatory milestones, product development activities, advantages, disadvantages, safety, and efficacy, etc.?
• How many companies are developing therapies for the treatment of LEMS?
• How many emerging therapies are in the mid-stage and late stages of development for the treatment of LEMS?
• What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the LEMS therapies?
• What are the recent novel therapies, targets, mechanisms of action and technologies developed to overcome the limitation of existing therapies?
• What are the clinical studies going on for LEMS and their status?
• What are the key designations that have been granted for the emerging therapies for LEMS?
• What are the 7MM historical and forecasted market of LEMS?
Reasons to buy
• The report will help in developing business strategies by understanding trends shaping and driving the LEMS.
• To understand the future market competition in the LEMS market and Insightful review of the key market drivers and barriers.
• Organize sales and marketing efforts by identifying the best opportunities for LEMS in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan.
• Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors.
• Organize sales and marketing efforts by identifying the best opportunities for the LEMS market.
• To understand the future market competition in the LEMS market.


1 Key Insights
2. Executive Summary
3. Lambert–Eaton Myasthenic Syndrome (LEMS): Market Overview at a Glance (Base Case Scenario)
3.1. Market Share (%) Distribution of LEMS in 2017
3.2. Market Share (%) Distribution of LEMS in 2030
4. Lambert–Eaton Myasthenic Syndrome (LEMS): Market Overview at a Glance (Downside Scenario)
4.1. Market Share (%) Distribution of LEMS in 2017
4.2. Market Share (%) Distribution of LEMS in 2030
5. Lambert–Eaton Myasthenic Syndrome (LEMS): Disease Overview
5.1. Introduction
5.2. Signs and Symptoms
5.3. Cause of Lambert–Eaton Myasthenic Syndrome
5.4. Risk Factors
5.5. Pathophysiology Lambert–Eaton Myasthenic Syndrome
5.6. Pathogenesis
5.7. Clinical Manifestations
5.8. Diagnosis
5.9. Diagnostic Algorithm
6. Case Reports
6.1. Lambert–Eaton Myasthenic Syndrome Associated with Atypical Bronchopulmonary Carcinoid Tumor
6.2. A Case of Lambert–Eaton Myasthenic Syndrome Associated with Atypical Bronchopulmonary Carcinoid Tumor
7. Epidemiology and Patient Population
7.1. Epidemiology Methodology
7.2. Key Findings
7.3. Total Prevalent Cases of Lambert–Eaton Myasthenic Syndrome (LEMS) in the 7MM
7.4. Total Diagnosed Prevalent Cases of Lambert–Eaton Myasthenic Syndrome (LEMS) in the 7MM
8. United States Epidemiology
8.1. Assumptions and Rationale
8.2. Total Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in the United States
8.3. Total Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in the United States
8.4. Gender-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in the United States
8.5. Type-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in the United States
8.6. Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) by Malignancy in the United States
9. EU-5 Epidemiology
9.1. Germany
9.1.1. Total Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Germany
9.1.2. Total Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Germany
9.1.3. Gender-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Germany
9.1.4. Type-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Germany
9.1.5. Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) by Malignancy in Germany
9.2. France
9.2.1. Total Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in France
9.2.2. Total Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in France
9.2.3. Gender-specific Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in France
9.2.4. Type-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in France
9.2.5. Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) by Malignancy in France
9.3. Italy
9.3.1. Total Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Italy
9.3.2. Total Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Italy
9.3.3. Gender-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Italy
9.3.4. Type-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Italy
9.3.5. Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) by Malignancy in Italy
9.4. Spain
9.4.1. Total Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Spain
9.4.2. Total Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Spain
9.4.3. Gender-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Spain
9.4.4. Type-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Spain
9.4.5. Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) by Malignancy in Spain
9.5. United Kingdom
9.5.1. Total Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in the United Kingdom
9.5.2. Total Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in the United Kingdom
9.5.3. Gender-specific Diagnosed Prevalent Cases of LEMS in the United Kingdom
9.5.4. Type-specific Diagnosed Prevalent Cases of LEMS in the United Kingdom
9.5.5. Diagnosed Prevalent Cases of LEMS by Malignancy in the United Kingdom
10. Japan Epidemiology
10.1. Assumptions and Rationale
10.2. Total Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Japan
10.3. Total Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Japan
10.4. Gender-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Japan
10.5. Type-specific Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) in Japan
10.6. Diagnosed Prevalent Cases of Lambert-Eaton Myasthenic Syndrome (LEMS) by Malignancy in Japan
11. Treatment
11.1. Treatment Guidelines
11.1.1. Italian recommendations for Lambert–Eaton myasthenic syndrome (LEMS) management
11.1.2. EFNS Guidelines: Guidelines for treatment of autoimmune neuromuscular transmission disorders
12. Unmet Needs
13. Marketed Drugs
13.1. Firdapse: Catalyst Pharmaceutical
13.1.1. Product Description
13.1.2. Other Developmental Activities
13.1.3. Clinical Development
13.1.4. Clinical Trials Information
13.1.5. Safety and Efficacy
13.1.6. Product Profile
13.2. Ruzurgi: Jacobus Pharmaceutical Company Inc.
13.2.1. Product Description
13.2.2. Other Developmental Activities
13.2.3. Clinical Development
13.2.4. Clinical Trials Information
13.2.5. Safety and Efficacy
13.2.6. Product Profile
14. Lambert–Eaton Myasthenic Syndrome (LEMS): 7MM Market Analysis
14.1. Market Methodology
14.2. Key Findings
14.3. Market Size of Lambert–Eaton Myasthenic Syndrome (LEMS) in 7MM (With Base Case Scenario)
14.4. Market Size of LEMS by Therapies in the 7MM (With Base Case Scenario)
14.5. Market Size of Lambert–Eaton Myasthenic Syndrome (LEMS) in the 7MM (With Downside Scenario)
14.6. Market Size of LEMS by Therapies in the 7MM (With Downside Scenario)
15. Market Outlook: The United States
15.1. United States Market Size
15.1.1. Total Market size of Lambert-Eaton Myasthenic Syndrome (LEMS) (With Base Case Scenario)
15.1.2. Lambert-Eaton Myasthenic Syndrome (LEMS) Market by Therapies (With Base Case Scenario)
15.1.3. Total Market size of Lambert-Eaton Myasthenic Syndrome (LEMS) (With Downside Scenario)
15.1.4. Lambert-Eaton Myasthenic Syndrome (LEMS) Market by Therapies (With Downside Scenario)
16. Market Outlook: Europe
16.1. Germany
16.1.1. Total Market size of Lambert–Eaton Myasthenic Syndrome (LEMS)
16.1.2. Lambert–Eaton Myasthenic Syndrome (LEMS) Market by Therapies
16.2. France
16.2.1. Total Market size of Lambert–Eaton Myasthenic Syndrome (LEMS)
16.2.2. Lambert–Eaton Myasthenic Syndrome (LEMS) Market by Therapies
16.3. Italy
16.3.1. Total Market size of Lambert–Eaton Myasthenic Syndrome (LEMS)
16.3.2. Lambert–Eaton Myasthenic Syndrome (LEMS) Market by Therapies
16.4. Spain
16.4.1. Total Market size of Lambert–Eaton Myasthenic Syndrome (LEMS)
16.4.2. Lambert–Eaton Myasthenic Syndrome (LEMS) Market by Therapies
16.5. United Kingdom
16.5.1. Total Market size of Lambert–Eaton Myasthenic Syndrome (LEMS)
16.5.2. Lambert–Eaton Myasthenic Syndrome (LEMS) Market by Therapies
17. Market Outlook: Japan
17.1. Total Market size of Lambert–Eaton Myasthenic Syndrome (LEMS)
17.2. Lambert–Eaton Myasthenic Syndrome (LEMS) Market by Therapies
18. Market Drivers
19. Market Barriers
20. SWOT Analysis
21. KOL Views
22. Reimbursement and market access
23. Appendix
23.1. Report Methodology
24. DelveInsight Capabilities
25. Disclaimer
26. About DelveInsightTable 1 : 7MM Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology (2017-2030)
Table 2 : 7MM Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases (2017-2030)
Table 3 : Disease% Epidemiology in the United States (2017-2030)
Table 4 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in the United States (2017-2030)
Table 5 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in Germany (2017-2030)
Table 6 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in Germany (2017-2030)
Table 7 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in France (2017-2030)
Table 8 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in France (2017-2030)
Table 9 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in Italy (2017-2030)
Table 10 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in Italy (2017-2030)
Table 11 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in Spain (2017-2030)
Table 12 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in Spain (2017-2030)
Table 13 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in the UK (2017-2030)
Table 14 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in the UK (2017-2030)
Table 15 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in Japan (2017-2030)
Table 16 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in Japan (2017-2030)
Table 17 : Drug Name, Clinical Trials by Recruitment status
Table 18 : Drug Name, Clinical Trials by Zone
Table 19 : Total Seven Major Market Size in USD, Million (2017-2030)
Table 20 : Region-wise Market Size in USD, Million (2017-2030)
Table 21 : 7MM-Market Size by Therapy in USD, Million (2017-2030)
Table 22 : United States Market Size in USD, Million (2017-2030)
Table 23 : United States Market Size by Therapy in USD, Million (2017-2030)
Table 24 : Germany Market Size in USD, Million (2017-2030)
Table 25 : Germany Market Size by Therapy in USD, Million (2017-2030)
Table 26 : France Market Size in USD, Million (2017-2030)
Table 27 : France Market Size by Therapy in USD, Million (2017-2030)
Table 28 : Italy Market Size in USD, Million (2017-2030)
Table 29 : Italy Market Size by Therapy in USD, Million (2017-2030)
Table 30 : Spain Market Size in USD, Million (2017-2030)
Table 31 : Spain Market Size by Therapy in USD, Million (2017-2030)
Table 32 : United Kingdom Market Size in USD, Million (2017-2030)
Table 33 : United Kingdom Market Size by Therapy in USD, Million (2017-2030)
Table 34 : Japan Market Size in USD, Million (2017-2030)
Table 35 : Japan Market Size by Therapy in USD, Million (2017-2030)
*The list of tables is not exhaustive; the final content may varyFigure 1 : 7MM Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology (2017-2030)
Figure 2 : 7MM Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases (2017-2030)
Figure 3 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in the United States (2017-2030)
Figure 4 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in the United States (2017-2030)
Figure 5 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in Germany (2017-2030)
Figure 6 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in Germany (2017-2030)
Figure 7 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in France (2017-2030)
Figure 8 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in France (2017-2030)
Figure 9 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in Italy (2017-2030)
Figure 10 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in Italy (2017-2030)
Figure 11 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in Spain (2017-2030)
Figure 12 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in Spain (2017-2030)
Figure 13 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in the UK (2017-2030)
Figure 14 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in the UK (2017-2030)
Figure 15 : Lambert-Eaton Myasthenic Syndrome (LEMS) Epidemiology in Japan (2017-2030)
Figure 16 : Lambert-Eaton Myasthenic Syndrome (LEMS) Diagnosed and Treatable Cases in Japan (2017-2030)
Figure 17 : Drug Name, Clinical Trials by Recruitment status
Figure 18 : Drug Name, Clinical Trials by Zone
Figure 19 : Total Seven Major Market Size in USD, Million (2017-2030)
Figure 20 : Region-wise Market Size in USD, Million (2017-2030)
Figure 21 : 7MM-Market Size by Therapy in USD, Million (2017-2030)
Figure 22 : United States Market Size in USD, Million (2017-2030)
Figure 23 : United States Market Size by Therapy in USD, Million (2017-2030)
Figure 24 : Germany Market Size in USD, Million (2017-2030)
Figure 25 : Germany Market Size by Therapy in USD, Million (2017-2030)
Figure 26 : France Market Size in USD, Million (2017-2030)
Figure 27 : France Market Size by Therapy in USD, Million (2017-2030)
Figure 28 : Italy Market Size in USD, Million (2017-2030)
Figure 29 : Italy Market Size by Therapy in USD, Million (2017-2030)
Figure 30 : Spain Market Size in USD, Million (2017-2030)
Figure 31 : Spain Market Size by Therapy in USD, Million (2017-2030)
Figure 32 : United Kingdom Market Size in USD, Million (2017-2030)
Figure 33 : United Kingdom Market Size by Therapy in USD, Million (2017-2030)
Figure 34 : Japan Market Size in USD, Million (2017-2030)
Figure 35 : Japan Market Size by Therapy in USD, Million (2017-2030)
*The list of figures is not exhaustive; the final content may vary.

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