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Published by: BCC Research
Published: Mar. 1, 2002 - 214 Pages
Table of Contents
Title
Introduction
Reason For Doing The Study
Study Goal And Objectives
Contributions Of The Study And For Whom
Scope And Format
Methodology And Information Sources
Analyst's Credentials
Other Relevant Bcc Reports And Publications
Bcc On-Line Services
Internet
Summary
Overview
Identification Of Stem Cells
U.S Regulation
Devices
Biologicals
Orphan Product Status
International Issues
Iso 9000
Reimbursement Issues
Markets For Cell And Tissue Therapies
Effects Of An Aging Population On Demand
Types Of Stem Or Progenitor Cells
A Paradigm Shift In Developmental Biology
Autologous Cells
Allogeneic Cells
Umbilical Cord Blood
Embryonic Stem Cells
Nih Guidelines
Utility Of Es Cells
Germ Cells
Therapeutic Cloning
Ethical Considerations
Position Of The Catholic Church
Position Of The National Academy Of Sciences
Access To The Fruits Of Research
Politics And Federal Funding
Patents
Cell-Based Gene Therapy
Applications For Progenitor Cell Therapies
Blood
Uses Of Hematopoietic Stem Cells
Source Of Hematopoietic Stem Cells
Bone Marrow
Peripheral Blood Progenitor Cell Collection
Designer Stem Cells
Stromal Cells
Products And Services In Support Of Hematopoietic Stem Cell Transfers
Cytokines For Stem Cell Therapy
G-Csf And Gm-Csf
Stemgen (Stf)
Mobista (Flt-3 Ligand)
Market Opportunity For Cytokines
Purification And Expansion Of Hematopoietic Stem Cells
Isolex 300i System
Dendreon, Inc.
Miltenyi Cell Selection Device
Eligix Hdm Cell Selection Systems
Aastromreplicell—Stem Cell Expansion
Select Therapeutics Transstem System
Purity Of Stem Cells: A Good Thing? Or Not?
Fractionation Of Stem Cells
Projected Sales Of Stem Cell Purification And Expansion Devices
Harvesting And Storage Of Umbilical Cord Blood
Graft-Versus-Host Disease
Cell Based Therapies
Market Opportunity For Gvhd Therapies
Immunodeficiency Diseases
Aids
The Disease
The Virus
The Pandemic
Natural Resistance
Current Therapies For Aids
Progenitor Cell Therapies For Aids
Market Opportunity For Aids Therapies
Skin
Skin Cell Progenitors
Burns
Ulcers
Epidermolysis Bullosa
Market Opportunity For Skin Cell Therapies
Bone
Bone Fractures
Bone Metabolism
Genetics Of Bone Formation
Current Therapies
Cell Therapy
Growth Factors And Morphogenetic Proteins
Market Opportunity To Treat Bone Fractures
Osteogenesis Imperfecta
Current Treatments
Market Opportunity To Treat Osteogenesis Imperfecta
Cartilage
Injuries Of The Knee
Markets For Knee Repair Products
Osteoarthritis
Epidemiology
Cell Therapies For Osteoarthritis
Teeth
Hair
Muscular Dystrophy
Possible Cell Therapies
Brain And Nervous System
Neural Stem Cells
Factors Supporting Nerve Cell Growth
Parkinson's Disease
Cell Therapies
Marketing Opportunity
Huntington's Disease
Cell Therapies For Huntington's Disease
Market Opportunity
Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
Cell Therapies
Epilepsy
Cell Therapies
Stroke
Cell Therapies
Market Opportunity
Spinal Cord Injury
Current Therapies
Cell Therapies
Market Opportunity
Eyes
Cell Therapies
Market Opportunity
Diabetes
Complications Of Diabetes
Current Treatments
Transplantation Of Cells To The Liver
Cell Therapies
Market Opportunity
Liver
Direct Infusion Of Porcine Liver Cells
Hepatocytes From Stem Cells
Market Opportunity
Heart
Congestive Heart Failure
Current Therapies
Cell Therapies
Coronary Heart Disease
Current Therapies
Cell Therapies
Marketing Opportunity For Heart Therapies
Vesicoureteral Reflux
Current Therapy
Cell Therapies
Marketing Opportunity
Solid Tumors
Brain Cancer
Cell-Based Cancer Vaccines
Marketing Opportunity
Autoimmune Disease
Multiple Sclerosis
Rheumatoid Arthritis And Related Diseases
Pathophysiology
Stem Cell Therapy
Inducing Immune Tolerance
Allogeneic Transplants
Xenotransplants
Opposition To Xenotransplants
Products Used For Progenitor Cell Therapies
Cell Separation/Purification
Dacs Stem Cell Kit
Clinimacs
Isolex Magnetic Cell Selection System
Stem Cell Expansion
Aastrom/Replicell System
Scaffolds For Seeding Cells
Polymer Implant For Cartilage Reconstruction
Bioseed B And Bioseed C
Autologous Cells
Carticel
Chondrogel
Epicel
Hgtv-43
Myocell
Vivescart
Vivescos
Vivescutan
Autologous Cell Based Gene Therapy
Argent Graft Versus Host Disease (Gvhd) Treatment
Cell Based Cancer Vaccines
Gvax Vaccines
Dendreon Therapeutic Cancer Vaccines
Dendricell
Hyalograft C
Laserskin Autograft
Regeimmune System
Transstem System
Allogeneic Cells
Allogen
Apligraf
Impact Products
Mesenchymal Stem Cells
Orcel
Pancreatic Stem Cells
Relicord
Transcord System
Vascugel
Vitrix
Xenotropic Cells
Diacrin's Porcine Cell Therapies
Organs
Bladder
Stem Cell Storage
Bioarchive Stem Cell System
Ccel Cellular Storage Freezer
Long Term Prospects
Structure Of The Industry
Company Profiles
Aastrom Biosciences
Advanced Cell Technology
Advanced Tissue Sciences
Alexion Pharmaceuticals
Amcell Corp.
Ariad Pharmaceuticals
Artecel Sciences
Baxter International
Bioheart
Biomira
Biotissue Technologies Ag
Biotransplant
Biowhittaker
Bresagen Limited
Cardion Ag
Cell Based Delivery
Cellfactors
Cell Genesys
Cell Therapeutics
Cord Blood Registry
Corixa
Cryo-Cell
Cythera, Inc.
Dendreon
Diacrin, Inc.
Encelle
Enzo Biochem
Fidia Advanced Biopolymers Srl
Genzyme Biosurgery
Geron Corp.
Incara Pharmaceuticals
Islet Technology
Isotis
Isto Technologies
Ixion Biotechnology
Kourion Therapeutics
Mesibo A/S
Morphogenesis, Inc.
Neoprobe Corp.
Neuralstem Biopharmaceuticals
Neuronyx
Nexell Therapeutics
Novartis International Ag
Ns Gene A/S
Organogenesis
Ortec International
Osiris Therapeutics
Progenitor Cell Therapy, Llc
Proneuron Biotechnologies
Select Therapeutics
Stemcells California
Targeted Genetics
Thermogenesis
Thm Biomedical
Tosk
Viacell
Wicell Research Institute
Appendix: Glossary Of Terms And Abbreviations
List Of Tables
Summary Table:
Projected Revenues For Progenitor Cell Therapies, Through 2007
1 Derivation Of Body Tissue Types From Germ Layers
2 Descendants Of The Human Mesenchymal Stem Cell (Hmsc)
3 Cell Types Derived From Embryonic Stem Cells In Vitro
4 Markers Of Pluripotent Cells In Mouse, Man And Monkey
5 Food And Drug Administration Bodies Involved In Implant Regulation
6 Causes Of Death In The U.S., 1998
7 Change In Population Structure, Through 2007
8 Change In U.S. Population Structure By Age Group, Through 2007
9 Annual Physician's Office Visits In The U.S. By Age, 1999
10 Diseases Treated Using Cord Blood
11 Umbilical Cord Blood Banks
12 Cell Lines That Meet Criteria For Federal Funding
13 Diseases Treated With Blood Stem Cells
14 Commercial Opportunities With Regard To Stem Cell Transplantation
15 Estimated Sales Of Cytokines Used For Hematopoietic Stem Cell Treatments, Through 2007
16 Estimated Revenues From Stem Cell Isolation And Expansion Systems, Through 2007
17 Cryo-Cell Revenues For Harvesting And Storing Blood, Through 2001
18 Worldwide Revenues From Cord Blood Harvest And Storage, Through 2006
19 Hiv/Aids Statistics, End Of 2000
20 Market Opportunity For Aids Cell Therapies, Through 2007
21 U.S. Commercial Sales Of Apligraf, Through 2001
22 Revenues For Skin Living Cell Therapies, Through 2007
23 Bone Morphogenic Proteins (Bmp) Or Growth Factors Under Development
24 Fractures Requiring Hospitalization In The U.S. By Age And Sex, 1996
25 Worldwide Sales Of Cell Therapy Products To Repair The Cartilage, Through 2007*
26 Prevalence Of Arthritis In The U.S., 1999 Estimates
27 Organizations That Support Research On Spinal Injury
28 Revenue Projections For Corneal Stem Cell Procedures, Through 2007
29 Prevalence Of Congestive Heart Failure In The U.S. By Age And Sex, 1998
30 Projected Revenues From Cancer Vaccines, Through 2007
31 Cancer Vaccines Under Development At Dendreon
32 Disease Targets For Diacrin's Porcine Cell Therapies
33 Umbilical Cord Blood Storage Companies
34 Hematopoietic Stem Cell Therapy Companies
35 Nerve Progenitor Cell Therapy Companies
36 Mesenchymal Progenitor Cell Therapy Companies
37 Islet Or Pancreas Progenitor Cell Therapy Companies
38 Liver Progenitor Cell Therapy Companies
39 Embryonic Stem Cell Companies
List Of Figures
Summary Figure:
Projected Revenues For Progenitor Cell Therapies, 2001 And 2007
1 Change In Population Structure, 1997 And 2007
2 Hematopoiesis
3 Estimated Sales Of Cytokines Used For Hematopoietic Stem Cell Treatments, 2001 And 2007
4 Estimated Revenues From Stem Cell Isolation And Expansion Systems, 2001 And 2007
5 Worldwide Sales Of Cell Therapy Products To Repair The Cartilage, 2001 And 2007*
AbstractThis report focuses on the use of cells as medical therapy. This includes, for example, the replacement of the blood and immune systems with blood stem cells, the use of neural stem cells to treat neurodegenerative systems, the use of mesenchymal stem cells to repair bones and joints, liver stem cells for liver failure, and the potential use of "therapeutic cloning" to repair other tissues. This report is necessary and timely because of the rapid advances that have been made in the field - cell therapies in the pipeline have the potential to replace many of the pharmaceuticals currently marketed to treat chronic diseases, like Parkinson's disease and diabetes. Companies involved in stem cell therapies are profiled and markets are estimated for these therapies through 2005.
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