Paget's Disease of Bone (PDB) Therapeutics - Pipeline Assessment and Market Forecasts to 2018

Published by: GlobalData

Published: Dec. 19, 2011 - 55 Pages


Table of Contents

1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Paget’s Disease of Bone Therapeutics - Introduction
2.1 Disease Overview
2.2 Etiology
2.3 Pathophysiology
2.4 Risk Factors
2.5 Symptoms
2.6 Complications
2.7 Epidemiology
2.8 Diagnosis
2.8.1 Clinical Evaluation
2.8.2 Radiology
2.8.3 Biochemical Tests
2.8.4 Histological Tests
2.9 Treatment
2.9.1 Non-Pharmacological Therapy
2.9.2 Pharmacological Therapy
2.9.3 Pain Management
2.9.4 Surgery
2.10 GlobalData Pipeline Report Guidance
3 Paget’s Disease of Bone Therapeutics - Market Characterization
3.1 Paget’s Disease of Bone Therapeutics Market Size (2005-2010) - Global
3.2 Paget’s Disease of Bone Therapeutics Market Forecast (2010-2018) - Global
3.3 Paget’s Disease of Bone Therapeutics Market Size (2005-2010) - The US
3.4 Paget’s Disease of Bone Therapeutics Market Forecast (2010-2018) - The US
3.5 Paget’s Disease of Bone Therapeutics Market Size (2005-2010) - The UK
3.6 Paget’s Disease of Bone Therapeutics Market Forecast (2010-2018) - The UK
3.7 Paget’s Disease of Bone Therapeutics Market Size (2005-2010) - France
3.8 Paget’s Disease of Bone Therapeutics Market Forecast (2010-2018) - France
3.9 Paget’s Disease of Bone Therapeutics Market Size (2005-2010) - Germany
3.10 Paget’s Disease of Bone Therapeutics Market Forecast (2010-2018) - Germany
3.11 Paget’s Disease of Bone Therapeutics Market Size (2005-2010) - Italy
3.12 Paget’s Disease of Bone Therapeutics Market Forecast (2010-2018) - Italy
3.13 Paget’s Disease of Bone Therapeutics Market Size (2005-2010) - Spain
3.14 Paget’s Disease of Bone Therapeutics Market Forecast (2010-2018) - Spain
3.15 Paget’s Disease of Bone Therapeutics Market Size (2005-2010) - Japan
3.16 Paget’s Disease of Bone Therapeutics Market Forecast (2010-2018) - Japan
3.17 Drivers and Barriers for Paget’s Disease of Bone Therapeutics Market
3.17.1 Drivers for the Paget’s Disease of Bone Therapeutics Market
3.17.2 Barrier for the Paget’s Disease of Bone Therapeutics Market
3.18 Key Events Impacting the Future Market
3.19 Opportunity and Unmet Need Analysis
3.20 Key Takeaway
4 Paget’s Disease of Bone Therapeutics - Competitive Assessment
4.1 Overview
4.2 Strategic Competitor Assessment
4.3 Product Profiles for the Major Marketed Products in the Paget’s Disease of Bone Therapeutics Market
4.3.1 Actonel (risedronate sodium)
4.3.2 Aredia (pamidronate disodium)
4.3.3 Didronel (etidronate disodium)
4.3.4 Fosamax (alendronate sodium)
4.3.5 Miacalcin (calcitonin salmon)
4.3.6 Reclast (zoledronic acid)
4.3.7 Skelid (tiludronate disodium)
4.4 Key Takeaway
5 Paget’s Disease of Bone Therapeutics - Pipeline Assessment
5.1 Overview
5.2 Strategic Pipeline Assessment
5.3 Paget’s Disease of Bone Therapeutics - Pipeline by Phases of Development
5.3.1 Paget’s Disease of Bone Therapeutics - Phase II Pipeline
5.4 Paget’s Disease of Bone Therapeutics - Pipeline by Mechanism of Action
5.4.1 Technology Trends Analytical Framework
5.5 Paget’s Disease of Bone Therapeutics - Promising Drugs with Novel Mechanisms of Action under Clinical Development
5.6 Profiles of Promising Drugs under Clinical Development
5.6.1 Oral Gallium
5.7 Key Takeaway
6 Paget’s Disease of Bone Therapeutics - Clinical Trials Mapping
6.1 Clinical Trials by Country
6.2 Clinical Trials by Phase
6.3 Clinical Trials by Trial Status
6.4 Overall Sponsors
6.5 Prominent Sponsors
7 Paget’s Disease of Bone Therapeutics - Strategic Assessment
7.1 Implications for Future Market Competition
8 Paget’s Disease of Bone Therapeutics - Future Players
8.1 Introduction
8.2 Company Profiles
8.2.1 Genta Incorporated
9 Paget’s Disease of Bone Therapeutics - Appendix
9.1 Market Definitions
9.2 Abbreviations
9.3 Methodology
9.3.1 Coverage
9.3.2 Secondary Research
9.3.3 Forecasting
9.3.4 Primary Research
9.3.5 Expert Panel Validation
9.4 Contact Us
9.5 Disclaimer
9.6 Bibliography
1.1 List of Tables
Table 1: Prevalence of Paget’s Disease of Bone in Major Markets
Table 2: Paget’s Disease of Bone Therapeutics Market, Global, Revenue ($m), 2005 - 2010
Table 3: Paget’s Disease of Bone Therapeutics Market, Global, Forecast ($m), 2010 - 2018
Table 4: Paget’s Disease of Bone Therapeutics Market, The US, Revenue ($m), 2005 - 2010
Table 5: Paget’s Disease of Bone Therapeutics Market, The US, Revenue ($bn), 2005 - 2010
Table 6: Paget’s Disease of Bone Therapeutics Market, The UK, Revenue ($m), 2005 - 2010
Table 7: Paget’s Disease of Bone Therapeutics Market, The UK, Forecast ($m), 2010 - 2018
Table 8: Paget’s Disease of Bone Therapeutics Market, France, Revenue ($m), 2005 - 2010
Table 9: Paget’s Disease of Bone Therapeutics Market, France, Forecast ($m), 2010 - 2018
Table 10: Paget’s Disease of Bone Therapeutics Market, Germany, Revenue ($m), 2005 - 2010
Table 11: Paget’s Disease of Bone Therapeutics Market, Germany, Forecast ($m), 2010 - 2018
Table 12: Paget’s Disease of Bone Therapeutics Market, Italy, Revenue ($m), 2005 - 2010
Table 13: Paget’s Disease of Bone Therapeutics Market, Italy, Forecast ($m), 2010 - 2018
Table 14: Paget’s Disease of Bone Therapeutics Market, Spain, Revenue ($m), 2005 - 2010
Table 15: Paget’s Disease of Bone Therapeutics Market, Spain, Forecast ($m), 2010 - 2018
Table 16: Paget’s Disease of Bone Therapeutics Market, Japan, Revenue ($m), 2005 - 2010
Table 17: Paget’s Disease of Bone Therapeutics Market, Japan, Forecast ($m), 2010 - 2018
Table 18: Paget’s Disease of Bone Therapeutics - Phase II Pipeline
Table 19: Paget’s Disease of Bone Therapeutics - Promising Drugs under Clinical development, 2011
Table 20: Paget’s Disease of Bone Therapeutics - Clinical Trials by Country, 2011
Table 21: Paget’s Disease of Bone Therapeutics - Clinical Trials by Phase, 2011
Table 22: Paget’s Disease of Bone Therapeutics - Clinical Trials by Status, 2011
Table 23: Paget’s Disease of Bone Therapeutics - Clinical Trials by Overall Sponsors, 2011
Table 24: Paget’s Disease of Bone Therapeutics - Clinical Trials by Prominent Sponsors, 2011
Table 25: Paget’s Disease of Bone Therapeutics - Top Companies Participating in Therapeutics Clinical Trials, 2011
Table 26: Genta Incorporated, Musculoskeletal Pipeline, 2011
Table 27: Genta Incorporated, Paget’s Disease of Bone Pipeline, 2011
1.2 List of Figures
Figure 1: Histology of Normal and Pagetic Bone
Figure 2: Histology of Normal and Pagetic Bone under Polarized Light
Figure 3: Histology of Osteoclasts in Normal and Pagetic Bone
Figure 4: Tests Used for the Diagnosis of Paget’s Disease of Bone
Figure 5: Treatment Options for Paget’s Disease of Bone
Figure 6: Drugs Used for Treatment of Paget’s Disease of Bone
Figure 7: Paget’s Disease of Bone Therapeutics Market, Global, Revenue ($m), 2005 - 2010
Figure 8: Paget’s Disease of Bone Therapeutics, Market Share ($m), 2010
Figure 9: Paget’s Disease of Bone Therapeutics Market, Global, Forecast ($m), 2010 - 2018
Figure 10: Paget’s Disease of Bone Therapeutics, Market Share ($m), 2018
Figure 11: Paget’s Disease of Bone Therapeutics Market, The US, Revenue ($m), 2005 - 2010
Figure 12: Paget’s Disease of Bone Therapeutics Market, The US, Forecast ($m), 2010 - 2018
Figure 13: Paget’s Disease of Bone Therapeutics Market, The UK, Revenue ($m), 2005 - 2010
Figure 14: Paget’s Disease of Bone Therapeutics Market, The UK, Forecast ($m), 2010 - 2018
Figure 15: Paget’s Disease of Bone Therapeutics Market, France, Revenue ($m), 2005 - 2010
Figure 16: Paget’s Disease of Bone Therapeutics Market, France, Forecast ($m), 2010 - 2018
Figure 17: Paget’s Disease of Bone Therapeutics Market, Germany, Revenue ($m), 2005 - 2010
Figure 18: Paget’s Disease of Bone Therapeutics Market, Germany, Forecast ($m), 2010 - 2018
Figure 19: Paget’s Disease of Bone Therapeutics Market, Italy, Revenue ($m), 2005 - 2010
Figure 20: Paget’s Disease of Bone Therapeutics Market, Italy, Forecast ($m), 2010 - 2018
Figure 21: Paget’s Disease of Bone Therapeutics Market, Spain, Revenue ($m), 2005 - 2010
Figure 22: Paget’s Disease of BoneTherapeutics Market, Spain, Forecast ($m), 2010 - 2018
Figure 23: Paget’s Disease of Bone Therapeutics Market, Japan, Revenue ($m), 2005 - 2010
Figure 24: Paget’s Disease of Bone Therapeutics Market, Japan, Forecast ($m), 2010 - 2018
Figure 25: Paget’s Disease of Bone Therapeutics Market, Drivers and Barriers, 2011
Figure 26: Opportunity and Unmet Need in the Paget’s Disease of Bone Therapeutics Market
Figure 27: Paget’s Disease of Bone Therapeutics Market - Strategic Competitor Assessment, 2011
Figure 28: Paget’s Disease of Bone Therapeutics - Technology Trends Analytics Framework - Description, 2011
Figure 29: Paget’s Disease of Bone Therapeutics - Clinical Trials by Country, 2011
Figure 30: Implications for Future Market Competition in Paget’s Disease of Bone Therapeutic Market, 2011
Figure 31: Paget’s Disease of Bone Therapeutics - Pipeline by Company, 2011
Figure 32: GlobalData Market Forecasting Model

Abstract

Paget’s Disease of Bone (PDB) Therapeutics - Pipeline Assessment and Market Forecasts to 2018

Summary

GlobalData, the industry analysis specialist, has released its new report, “Paget’s Disease of Bone (PDB) Therapeutics - Pipeline Assessment and Market Forecasts to 2018”. The report is an essential source of information and analysis on the global PDB therapeutics market. The report identifies the key trends shaping and driving the global PDB therapeutics market. The report also provides insights on the prevalent competitive landscape and the emerging players expected to significantly alter the market positioning of the current market leaders. Most importantly, the report provides valuable insights on the pipeline products within the global PDB therapeutics sector. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData’s team of industry experts.

GlobalData’s analysis estimated the PDB therapeutics market to be worth $230.70m in 2010. It is forecast to decline at a Compound Annual Growth Rate (CAGR) of 5.3% to reach $148.68m by 2018. The decline is primarily attributed to the decreasing prevalence of PDB which eventually leads to a decline in the drug treated population. The scheduled patent expiries of Reclast, Fosamax, Miacalcin and Actonel are expected to cause the PDB market to further decline by leaving the PDB therapy arena vulnerable to generics.

Scope

The report provides information on the key drivers and challenges of the PDB therapeutics market. Its scope includes -
  • Annualized seven key markets (US, France, Germany, Italy, Spain, UK and Japan) PDB therapeutics market revenues data from 2005 to 2010, forecast for eight years to 2018.
  • Pipeline analysis data providing a split across the different phases, mechanisms of action being developed and emerging trends. Pipeline candidate for PDB fall under the therapeutic class of calcium resorption inhibitor.
  • Analysis of the current and future competition in the global PDB therapeutics market. The key market player covered is Genta Incorporated.
  • Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide a qualitative analysis of its implications.
  • Key topics covered include strategic competitor assessment, market characterization, unmet needs and the implications for the PDB therapeutics therapeutics market.
  • Analysis of key recent licensing and partnership agreements in PDB therapeutics market.
Reasons to buy

The report will enhance your decision making capability. It will allow you to -
  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the global PDB therapeutics market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments and companies likely to impact the global PDB therapeutics market in future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.
  • What’s the next big thing in the global PDB therapeutics market landscape? - Identify, understand and capitalize.


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