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Published by: Business Insights
Published: Oct. 1, 2009 - 162 Pages
Table of Contents
- Advances in the Stem Cell Industry
- Executive summary
- Background
- Stem cell research and development: scope and status
- Commercial landscape
- Industry landscape
- Chapter 1 Background
- Summary
- Introduction
- The building blocks of life
- About stem cells
- Potency
- Stem cell division
- Stem cell research
- Human ESCs
- Current status of knowledge
- Embryonic stem cells
- Growth and identification of ESCs
- Stimulating ESCs to differentiate
- Adult stem cells
- Cord blood stem cells
- Induced pluripotent stem cells
- Nuclear reprogramming
- Ethical and regulatory issues
- Situation in the US
- European regulations
- Chapter 2 Stem cell research and development: scope and status
- Summary
- Introduction
- Practical applications of stem cells
- Disease treatment
- Amyotrophic lateral sclerosis
- Parkinson's disease
- Spinal cord injury
- Alzheimer’s disease
- Cancer
- Heart disease
- Peripheral arterial disease
- Type 1 diabetes
- Liver failure
- Graft-versus-host disease
- Stem cell models: applications in drug discovery
- Screening studies
- Toxicity studies
- Practical benefits
- Some skepticism remains
- Chapter 3 Commercial landscape
- Summary
- Resisting the hyperbole
- Market realities
- Cell-based therapy market
- Autologous SC therapy
- Allogeneic SC therapy
- Cord blood banks
- Market drivers
- Market
- Global market estimates and forecasts
- Global market by use
- Global market by country share
- Embryo vs. adult stem cells
- Investment opportunities
- Choosing a viable business model
- Matching the model to the circumstance
- Autologous therapy models
- Allogeneic therapy models
- Chapter 4 Industry landscape
- Summary
- Introduction
- Company profiles
- Aastrom Biosciences, Inc.
- Overview
- Pipeline
- Advanced Cell Technology, Inc.
- Overview
- Pipeline
- Collaboration
- Aldagen
- Overview
- Pipeline
- Collaboration
- Angioblast Systems, Inc.
- Overview
- Pipeline
- Athersys, Inc.
- Overview
- Pipeline
- Collaboration
- Financials
- Bioheart, Inc.
- Overview
- Pipeline
- Bionet
- Overview
- Collaboration
- Brainstorm Cell Therapeutics
- Overview
- Capricor, Inc.
- Overview
- Pipeline
- Collaboration
- Cardio3 BioSciences SA
- Overview
- Cellcyte Genetics
- Overview
- Pipeline
- Collaboration
- Cellerix SA
- Overview
- Pipeline
- CellGenix Technologie Transfer
- Overview
- Cytori Therapeutics, Inc.
- Overview
- Entest BioMedical, Inc.
- Overview
- ES Cell International
- Overview
- EvoStem Finland Oy
- Overview
- Fate Therapeutics, Inc.
- Overview
- Genzyme
- Collaboration
- Financials
- Geron
- Overview
- Pipeline
- Healtheuniverse, Inc.
- Overview
- Innovacell Biotechnologie AG
- Overview
- International Stem Cell Corporation (ISCO)
- Overview
- Financing
- iPierian, Inc.
- Overview
- Ixion Biotechnology, Inc.
- Overview
- Karocell Tissue Engineering AB
- Overview
- MedCell Bioscience Ltd
- Overview
- MediStem, Inc.
- Overview
- Pipeline
- Mesoblast Limited
- Overview
- Nephrogenix
- Overview
- Neuralstem, Inc.
- Overview
- Pipeline
- Collaboration
- OncoStem Pharma
- Overview
- Novocell, Inc.
- Overview
- NuVasive, Inc.
- Overview
- Osiris Therapeutics, Inc.
- Overview
- Pipeline
- Collaboration
- Financials
- Pharmicell Europe GmbH
- Overview
- PrimeGen Biotech
- Overview
- Opexa Therapeutics
- Overview
- Financing
- Financials
- Plureon
- Overview
- Pipeline
- Collaboration
- Proteonomix, Inc.
- Overview
- Regenerative Sciences, Inc.
- Overview
- ReNeuron
- Overview
- Pipeline
- Shenzhen Beike
- Overview
- Stematix, Inc.
- Overview
- StemCells, Inc.
- Overview
- Stem Cell Therapeutics
- Overview
- Stem Cell Therapy International
- Overview
- Stemedica Cell Technologies, Inc.
- Overview
- Stempeutics Research Pvt. Ltd.
- Overview
- t2cure GmbH
- Overview
- TICEBA GmbH
- Overview
- Tristem
- Overview
- Chapter 5 Appendix
- Methodology
- Glossary
- Index
- List of Figures
- Figure 1.1: Early embryonic development and later differentiation
- Figure 1.2: Stem cell division
- Figure 1.3: Induced pluripotent stem cells
- Figure 2.4: Stem cell opportunities in disease treatment and R&D
- Figure 3.5: Forces affecting the stem cell market
- Figure 3.6: Key challenges faced when developing autologous therapy
- Figure 4.7: Type and number of regenerative medicine organizations
- List of Tables
- Table 3.1: Global stem cell market ($m), 2008-14
- Table 3.2: Potential US patient populations for cell-based therapies
- Table 3.3: Stem cell market by main uses ($m), 2008-14
- Table 3.4: Country breakdown of stem cell market ($m), 2008-14
- Table 3.5: Leading cell-based regenerative medicine products
AbstractAn important milestone in the development of stem cell technology occurred in 2007, when researchers induced human cells into a stem cell state using defined genetic factors. These cells are now known as induced pluripotent stem (IPS) cells; they offer an alternative to using embryonic stem cells. This report takes the implications of IPS cells and other developments into account. Some essential technologies are already in place and stem-cell based therapies have already begun to appear in the marketplace. The stem cell market is already divided into three segments—cell-based treatments, umbilical cord blood banking, and the use of stem cells to evaluate the efficacy and safety of new drugs developed by other methods. Global sales reached $410 million in 2008, and will grow to $2.68 billion by 2012. This growth will reach a projected $5.1 billion in 2014, providing a realistic, and even cautious forecast of the commercial potential these segments.
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