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U.S. DNA Sequencing Technology Markets

Published by: Frost & Sullivan

Published: Dec. 6, 2006 - 171 Pages


Table of Contents


1. Executive Summary
        1. Market Overview
                  1. Introduction
 
2. Total DNA Sequencing Technology Market
        1. Market Overview
                  1. Introduction
                  2. Scope and Segmentation
                  3. Research Methodology
                  4. Market Engineering Measurements
        2. Market Forecast and Competitive Analysis
                  1. Revenue Forecasts
                  2. Competitive Structure
                  3. Market Share Analysis
                  4. Partnerships Mergers and Acquisitions
        3. Market Challenges and Strategic Recommendations
                  1. Industry Challenges
                  2. Strategic Recommendations
 
3. Chain Terminator DNA Sequencing Market
        1. Market Overview
                  1. Introduction
                  2. Market Engineering Measurements
        2. Market Drivers and Restraints
                  1. Market Drivers
                  a. Utilization of Low-to-medium Throughput Technologies Sustains the Majority of Revenue Generation
                  b. Applications Specific to Directed Sequencing Support Market Segment Performance
                  c. Commercialization of Sequencing-based Diagnostic Applications Propels Market Growth
                  d. Utilization of Hybrid Approach to Sequencing Promotes Large-scale Genome Sequencing
                  e. Publicly Funded Large-scale Genome Sequencing Efforts Bolster Revenue Growth from Consumables Sales
                  f. Falling Costs Associated with Technological Advancements and Workflow Optimization Boost Applications
                  2. Market Restraints
                  a. Inefficiency and Costliness of Technology Prevent Utilization
                  b. Saturated Market for High-throughput Technologies Limits Growth of Install Base
                  c. Market Disruption Made by Next Generation DNA Sequencing Technologies Hinders Adoption Rates
                  d. Complexity of Upstream Sample Preparation Deters Adoption and Decentralization of Install Base
                  e. Competition by Alternative Genomics Technologies Constrains Market Share
                  f. Economic Advantage of Outsourcing Curbs Decentralization of Instrumentation
                  g. Reagent Dilution Slows Revenue Generation from Consumables Sales
        3. Technology and Market Trends
                  1. Technology Trends
                  2. Market Trends
        4. Market Forecasts and Competitive Analysis
                  1. Revenue Forecasts
                  2. Competitive Structure
                  3. Market Share Analysis
 
4. Next Generation DNA Sequencing Market
        1. Market Overview
                  1. Introduction
                  2. Market Engineering Measurements
        2. Market Drivers and Restraints
                  1. Market Drivers
                  2. Market Restraints
        3. Technology and Market Trends
                  1. Technology Trends
                  2. Market Trends
        4. Market Forecasts and Competitive Analysis
                  1. Revenue Forecasts
                  2. Competitive Structure
                  3. Market Share Analysis
 
5. Decision Support Database
        1. Decision Support Database
                  1. Number of Biotechnology Companies
                  2. Private Investment in Biotechnology
                  3. Government Biotechnology R&D Investment
                  4. Total Healthcare Expenditures


List of Figures


  • Total DNA Sequencing Technology Market: Revenue Forecasts (U.S.), 2002-2012
  • Total DNA Sequencing Technology Market: Revenue Forecasts by Segment (U.S.), 2002-2012
  • Total DNA Sequencing Technology Market: Percent of Revenues by Segment (U.S.), 2002-2012
  • Total DNA Sequencing Technology Market: Competitive Structure (U.S.), 2005
  • Total DNA Sequencing Technology Market: Company Market Share by Revenues (U.S.), 2005
  • Total DNA Sequencing Technology Market: Impact of Top Industry Challenges (U.S.), 2006-2012
  • Total DNA Sequencing Technology Market: Challenges and Corresponding Strategic Recommendations (U.S.), 2006-2012
  • Chain Terminator DNA Sequencing Market: Market Drivers Ranked in Order of Impact (U.S.), 2006-2012
  • Chain Terminator DNA Sequencing Market: Market Restraints Ranked in Order of Impact (U.S.), 2006-2012
  • Chain Terminator DNA Sequencing Market: Public Funding for Large-scale Sequencing Projects by Aim (U.S.), 2002-2012
  • Chain Terminator DNA Sequencing Market: Percent of Public Funding for Large-scale Sequencing Projects by Aim (U.S.), 2003-2012
  • Chain Terminator DNA Sequencing Market: Revenue Forecasts (U.S.), 2002-2012
  • Chain Terminator DNA Sequencing Market: Revenue Forecasts by Application (U.S.), 2002-2012
  • Chain Terminator DNA Sequencing Market: Percent of Revenues by Application (U.S.), 2002-2012
  • Chain Terminator DNA Sequencing Market: Competitive Structure (U.S.), 2005
  • Chain Terminator DNA Sequencing Market: Company Market Share by Revenues (U.S.), 2005
  • Next Generation DNA Sequencing Market: Market Drivers Ranked in Order of Impact (U.S.), 2006-2012
  • Next Generation DNA Sequencing Market: Revenue Forecasts for Related Genetic Analysis Technologies (U.S.), 2006 and 2010
  • Next Generation DNA Sequencing Market: Public Funding for Technology Development by Initiative (U.S.), 2004-2012
  • Next Generation DNA Sequencing Market: Market Restraints Ranked in Order of Impact (U.S.), 2006-2012
  • Next Generation DNA Sequencing Market: Revenue Forecasts (U.S.), 2002-2012
  • Next Generation DNA Sequencing Market: Competitive Structure (U.S.), 2005
  • Next Generation DNA Sequencing Market: Company Market Share by Revenues (U.S.), 2005





Abstract

Research Overview

This Frost & Sullivan research service titled U.S. DNA Sequencing Technology Markets provides revenue forecasts for the overall market as well as for the chain terminator DNA sequencing and the next-generation DNA sequencing segments with detailed market trends for specific applications, end users, and technologies. It also provides an in-depth analysis of market-wide and segment-specific drivers, restraints, and challenges with the corresponding strategic recommendations. In this research service, Frost & Sullivan's expert analysts thoroughly examine the following technologies: chain terminator and next-generation DNA sequencing.

Market Sectors

Expert Frost & Sullivan analysts thoroughly examine the following market sectors in this research:
  • Chain terminator DNA sequencing technologies
  • Next-generation DNA sequencing technologies
Technologies

The following technologies are covered in this research:
  • Chain terminator DNA sequencing
  • Next-generation DNA sequencing
Market Overview

Market Participants Must Focus on Evolving Aims of Genomics Research


The DNA sequencing technology markets in the United States, comprising chain terminator and next-generation DNA sequencing technologies, are characterized by constant technological innovation. While the chain terminator sequencing market has been steadily evolving from discovery-based to validation- and commercialization-based research, ongoing technological advances in next-generation sequencing are attracting many new participants to this market. "Customers have started taking their research to the next level - from populating databases with new sequence information to going back to validating important regions," notes the analyst of this research service. "DNA sequencing technology market participants must strategically position their chain terminator and next-generation DNA sequencing technologies with applications that enable customers to seamlessly make the research transition from discovery to validation."

Given the dynamism of the DNA sequencing market, it is critical for companies to develop specific applications for each stage of its evolution. Adopting this strategy can help them maintain revenue streams, while gearing up for the challenge of penetrating future markets for clinical applications of DNA sequencing technologies. By structuring their business strategies around the incremental steps towards the realization of personalized genomics, companies are more likely to develop revenue models that set off the high costs of driving DNA sequencing technology revenue streams. Correspondingly, developers and suppliers of DNA sequencing technologies need to focus efforts on taking the genomic revolution from the bench top to the bedside. Only then will they be able to realize the significant revenue and profit potential of molecular diagnostics, pharmacogenomics, drug discovery and development, and personalized genomics.

Personalized Medicine on the Brink of Huge Growth

Numerous critical issues in the DNA sequencing technology market need to be resolved before the healthcare industry can witness the explosive growth of pharmacogenomics and personalized medicine. Cancer research, for instance, is hampered by various problems such as undetermined protocols for tumor sequencing and the lack of a cost-effective and efficent tumor sequencing technology. Additionally, there are very high expectations of next-generation DNA sequencing technologies that sometimes border on the unrealistic. Nevertheless, the healthcare industry has identified the tangible and hugely beneficial results of genomics, molecular diagnostics, pharmacogenomics, and personalized medicine. Despite the existence of only a few genetic technologies that have been validated for use in clinically licensed and regulated laboratories, and the presence of barely a handful of personalized medicines in the market, the constantly increasing rate of genetic marker discovery has led to renewed optimism in the healthcare industry.

In general, the industry is united in its belief that the next 10 to 15 years will see the emergence of a technology that is capable of sequencing an entire human genome for approximately $1,000. "Such technologies will boost the further escalation of discovery, which in turn, will lead to an even greater focus on pharmacogenomic development," says the analyst. "The cycles of sustained and then hastening rates of discovery will ultimately help establish pharmacogenomics and personalized medicine as permanent parts of healthcare." Experts believe that the personalized medicine revolution will gather pace slowly at first, and then start growing in leaps and bounds. DNA sequencing market participants must keep pace with this evolutionary process to be able to address the challenges and opportunities that come with each phase of development.

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