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Published by: Drug and Market Development Publishing
Published: Sep. 10, 2004 - 553 Pages
Table of Contents
2 Introduction, Scope, and Objectives
- Early Status and Current Products
- Driving Forces
- Customers
- Competition
- Scope and Objective
3 Hybridoma Technology and Antibody Gene Manipulation
- Introduction
- Historical Roots
- Classical Antibody Development
- Hybridoma Technology
- Molecular Biology Applied to Antibody Characterization
- References
4 Status of Recombinant Antibody Products
- Historical Notes: Introduction
- Therapeutic Anticancer Antibodies
- Naked vs. Immunocojugated Recombinant Antibodies
- Cardiovascular Disorders
- Diagnostic Antibodies
- Infl ammatory Diseases
- Transplantation
- Outlook for the Future
- References
5 Clinical Studies
- Approved Antibody Therapeutics
- Therapeutic Antibodies in Development
- Failed Antibody Therapeutics
- Status of a Few Selected On-Going Clinical Studies
6 Large-scale Manufacture of Antibodies
- Introduction: Companies Involved
- Technologies
- Is There a Shortage in Manufacturing Capability?
- References
7 Alliances and Partnerships
- Trends in Alliance-Building
- Business Model
- Business Deals
- Recent Collaborations and Partnerships
- Mergers and Acquisition
8 Patents and Intellectual Properties
- Introduction
- Antibody Humanization
- Human Antibody Technology
- Court Rulings Regarding Importing Data
- Patent Infringement Litigation and Cross-licensing
- The Single-Chain Antibody Technology
- Recently Issued Patents
9 Therapeutic Antibody Companies: In-depth Profi les
10 Market Status and Strategic Issues
- Biotechnology Financing
- Revenue Status
- New Product Approvals
11 Strategic Issues
- Business Environment
- Product Failures and Future Prospects
- Bioterrorism and Vaccines
- “omics”: Implications in MAb Development
- Challenges in Therapeutic MAb Production
- Prognosis
AbstractThis Report analyzes the most noteworthy and up-to-date developments of the MAb field including, technologies, clinical studies, partnership & alliances, intellectual property issues, production, and manufacturing. The Report provides an in-depth examination of the market status and strategic outlook of the antibody market place. In addition, the intellectual property landscape in this area is summarized and companies invested in antibody therapeutics are profiled.
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