Global RNAi Therapeutics Market: Analysis By Molecule Type, By Application, By Region Size and Trends with Impact of COVID-19 and Forecast up to 2026

Global RNAi Therapeutics Market: Analysis By Molecule Type, By Application, By Region Size and Trends with Impact of COVID-19 and Forecast up to 2026

The report provides an in depth analysis of the Global RNAi therapeutics market by value, by molecule type, by application, by region, etc. The report provides a regional analysis of the RNAi therapeutics market, including North America (The US, Canada, and Mexico), Europe, Asia Pacific, Middle East & Africa, and Latin America. The report further provides the detailed analysis of the US market on the basis of molecule type, and application. The report also provides an analysis of the COVID-19 impact on the RNAi therapeutics market.

The report also assesses the key opportunities in the market and outlines the factors that are and will be driving the growth of the industry. Growth of the overall RNAi therapeutics market has also been forecasted for the period 2022-2026, taking into consideration the previous growth patterns, the growth drivers and the current and future trends.

The global RNAi therapeutics market is concentrated. The key players of the global RNAi therapeutics market are Moderna Inc., Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., and Silence Therapeutics Inc. are also profiled with their financial information and respective business strategies.

Company Coverage

Moderna Inc.
Alnylam Pharmaceuticals Inc.
Ionis Pharmaceuticals Inc.
Silence Therapeutics Inc.

Regional Coverage

North America
Europe
Asia Pacific
Middle East & Africa
Latin America

Executive Summary

The RNAi therapeutics market can be segmented on the basis of molecule type (small interference RNA (siRNA), and micro RNA (miRNA)), and application (oncology, cardiovascular disorders, respiratory disorders, renal diseases, genetic disorders, neurodegenerative disorders, infectious diseases, and others).

While most of the industries worldwide suffered a negative impact of COVID-19, the RNAi therapeutics market witnessed a positive impact on it. Initially, the market witnessed a sudden spike in the demand, since the relevance of RNAi research in understanding the COVID-19 virus started growing mainly during the initial worldwide outbreak of COVID-19, in 2020. Later in the year 2020, the market witnessed several investments from both public and private investors in pharma R&D laboratories to conduct various studies and experiments to find out vaccines to prevent the spread of virus. Many pharmaceutical businesses are actively commercializing their medications in order to improve profits and attract additional investment capital.

The global RNAi therapeutics market has increased during the years 2020-2021 and projections are made that the market would rise in the next four years i.e. 2022-2026. The global RNAi therapeutics market is expected to increase due to significant increase in investment, increased prevalence of infectious diseases, rise in incidence of cancer, rising prevalence of diabetes, and rising genetic and metabolic disorders. Yet the market faces some challenges such as, high development cost of RNA interference-based drugs, stringent regulations and long product approval process, unstable potentially immunogenic nature of RNA, etc.


1. Executive Summary
2. Introduction
2.1 RNA-based Therapeutics: An Overview
2.1.1 Types of RNA-based Therapeutics
Table 1: Types of RNA-based Therapeutics
2.1.2 History of RNA-based Therapeutics
Table 2: History of RNA-based Therapeutics
2.1.3 Advantages of RNA-based Therapeutics
Table 3: Advantages of RNA-based Therapeutics
2.2 RNA interference (RNAi) Therapeutics: An Overview
2.2.1 Mechanism of RNA interference (RNAi) Therapeutics
Table 4: Mechanism of RNA interference (RNAi) Therapeutics
2.2.2 Steps of RNA interference (RNAi) Therapeutics
2.2.3 Applications of RNA interference (RNAi) Therapeutics
Table 6: Applications of RNA interference (RNAi) Therapeutics
2.2.4 RNAi Therapeutics: Platform Comparison
Table 7: RNAi Therapeutics: Platform Comparison
2.2.5 Advantages and Disadvantages of RNA interference (RNAi) Therapeutics
Table 8: Advantages and Disadvantages of RNA interference (RNAi) Therapeutics
2.3 RNA interference (RNAi) Therapeutics: Segmentation by Molecule Type
Table 9: RNA interference (RNAi) Therapeutics Segmentation by Molecular Type
2.4 RNA interference (RNAi) Therapeutics: Segmentation by Application
Table 10: RNA interference (RNAi) Therapeutics Segmentation by Application
3. Global Market Analysis
3.1 Global RNAi Therapeutics Market: An Analysis
3.1.1 Global RNAi Therapeutics Market by Value
Table 11: Global RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 12: Global RNAi Therapeutics Market by Value; 2022-2026 (US$ Billion)
3.1.2 Global RNAi Therapeutics Market by Molecule Type (Small Interfering RNAs (siRNA) and Micro RNAs (miRNA))
Table 13: Global RNAi Therapeutics Market by Molecule Type; 2021 (Percentage, %)
3.1.3 Global RNAi Therapeutics Market by Application (Oncology, Cardiovascular Disorders, Respiratory Disorders, Renal Diseases, Genetic Disorders, Neurodegenerative Disorders, Infectious Diseases, and Other)
Table 14: Global RNAi Therapeutics Market by Application; 2021 (Percentage, %)
3.1.4 Global RNAi Therapeutics Market by Region (North America, Europe, Asia Pacific, Middle East & Africa, and Latin America)
Table 15: Global RNAi Therapeutics Market by Region; 2021 (Percentage, %)
3.2 Global RNAi Therapeutics Market: Molecule Type Analysis
3.2.1 Global Small Interfering RNAs (siRNA) Therapeutics Market by Value
Table 16: Global Small Interfering RNAs (siRNA) Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 17: Global Small Interfering RNAs (siRNA) Therapeutics Market by Value; 2022-2026 (US$ Billion)
3.2.2 Global Micro RNAs (miRNA) Therapeutics Market by Value
Table 18: Global Micro RNAs (miRNA) Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 19: Global Micro RNAs (miRNA) Therapeutics Market by Value; 2022-2026 (US$ Million)
3.3 Global RNAi Therapeutics Market: Application Analysis
3.3.1 Global Oncology RNAi Therapeutics Market by Value
Table 20: Global Oncology RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 21: Global Oncology RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
3.3.2 Global Cardiovascular Disorders RNAi Therapeutics Market by Value
Table 22: Global Cardiovascular Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 23: Global Cardiovascular Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
3.3.3 Global Respiratory Disorders RNAi Therapeutics Market by Value
Table 24: Global Respiratory Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 25: Global Respiratory Disorders RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
3.3.4 Global Renal Diseases RNAi Therapeutics Market by Value
Table 26: Global Renal Diseases RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 27: Global Renal Diseases RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
3.3.5 Global Genetic Disorders RNAi Therapeutics Market by Value
Table 28: Global Genetic Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 29: Global Genetic Disorders RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
3.3.6 Global Neurodegenerative Disorders RNAi Therapeutics Market by Value
Table 30: Global Neurodegenerative Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 31: Global Neurodegenerative Disorders RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
3.3.7 Global Infectious Diseases RNAi Therapeutics Market by Value
Table 32: Global Infectious Diseases RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 33: Global Infectious Diseases RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
3.3.8 Global Other RNAi Therapeutics Market by Value
Table 34: Global Other RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 35: Global Other RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4. Regional Market Analysis
4.1 North America RNAi Therapeutics Market: An Analysis
4.1.1 North America RNAi Therapeutics Market by Value
Table 36: North America RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 37: North America RNAi Therapeutics Market by Value; 2022-2026 (US$ Billion)
4.1.2 North America RNAi Therapeutics Market by Molecule Type (Small Interfering RNAs (siRNA) and Micro RNAs (miRNA))
Table 38: North America RNAi Therapeutics Market by Molecule Type; 2021 (Percentage, %)
4.1.3 North America Small Interfering RNAs (siRNA) Therapeutics Market by Value
Table 39: North America Small Interfering RNAs (siRNA) Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 40: North America Small Interfering RNAs (siRNA) Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.4 North America Micro RNAs (miRNA) Therapeutics Market by Value
Table 41: North America Micro RNAs (miRNA) Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 42: North America Micro RNAs (miRNA) Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.5 North America RNAi Therapeutics Market by Application (Oncology, Cardiovascular Disorders, Respiratory Disorders, Renal Diseases, Genetic Disorders, Neurodegenerative Disorders, Infectious Diseases, and Other)
Table 43: North America RNAi Therapeutics Market by Application; 2021 (Percentage, %)
4.1.6 North America Oncology RNAi Therapeutics Market by Value
Table 44: North America Oncology RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 45: North America Oncology RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.7 North America Cardiovascular Disorders RNAi Therapeutics Market by Value
Table 46: North America Cardiovascular Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 47: North America Cardiovascular Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
4.1.8 North America Respiratory Disorders RNAi Therapeutics Market by Value
Table 48: North America Respiratory Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 49: North America Respiratory Disorders RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.9 North America Renal Diseases RNAi Therapeutics Market by Value
Table 50: North America Renal Diseases RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 51: North America Renal Diseases RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.10 North America Genetic Disorders RNAi Therapeutics Market by Value
Table 52: North America Genetic Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 53: North America Genetic Disorders RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.11 North America Neurodegenerative Disorders RNAi Therapeutics Market by Value
Table 54: North America Neurodegenerative Disorders RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 55: North America Neurodegenerative Disorders RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.12 North America Infectious Diseases RNAi Therapeutics Market by Value
Table 56: North America Infectious Diseases RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 57: North America Infectious Diseases RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.13 North America Other RNAi Therapeutics Market by Value
Table 58: North America Other RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 59: North America Other RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.14 North America RNAi Therapeutics Market by Region (The US, Canada, and Mexico)
Table 60: North America RNAi Therapeutics Market by Region; 2021 (Percentage, %)
4.1.15 The US RNAi Therapeutics Market by Value
Table 61: The US RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 62: The US RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.16 The US RNAi Therapeutics Molecule Type Market by Value
Table 63: The US RNAi Therapeutics Molecule Type Market by Value; 2021-2026 (US$ Million)
4.1.17 The US RNAi Therapeutics Application Market by Value
Table 64: The US RNAi Therapeutics Application Market by Value; 2021-2026 (US$ Million)
4.1.18 Canada RNAi Therapeutics Market by Value
Table 65: Canada RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 66: Canada RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.1.19 Mexico RNAi Therapeutics Market by Value
Table 67: Mexico RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 68: Mexico RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.2 Europe RNAi Therapeutics Market: An Analysis
4.2.1 Europe RNAi Therapeutics Market by Value
Table 69: Europe RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 70: Europe RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.3 Asia Pacific RNAi Therapeutics Market: An Analysis
4.3.1 Asia Pacific RNAi Therapeutics Market by Value
Table 71: Asia Pacific RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 72: Asia Pacific RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.4 Middle East & Africa RNAi Therapeutics Market: An Analysis
4.4.1 Middle East & Africa RNAi Therapeutics Market by Value
Table 73: Middle East & Africa RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 74: Middle East & Africa RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
4.5 Latin America RNAi Therapeutics Market: An Analysis
4.5.1 Latin America RNAi Therapeutics Market by Value
Table 75: Latin America RNAi Therapeutics Market by Value; 2020-2021 (US$ Million)
Table 76: Latin America RNAi Therapeutics Market by Value; 2022-2026 (US$ Million)
5. Impact of COVID
5.1 Impact of COVID-19 on Global RNAi Therapeutics Market
6. Market Dynamics
6.1 Growth Driver
6.1.1 Increasing Investments in RNAi Therapies
Table 77: Increasing Investment Deals in RNAi Therapeutics; 2018-2021
6.1.2 Rise in Incidence of Cancer
Table 78: Global New Cancer Cases Diagnosed; 2018 & 2020 (Million)
6.1.3 Rising Prevalence of Diabetes
Table 79: Global Diabetes Prevalence among Adults (20–79 years); 2021 & 2045 (Percentage, %)
6.1.4 Increased Prevalence of Infectious Diseases
6.1.5 Rising Genetic and Metabolic Disorders
6.2 Challenges
6.2.1 High Development Cost of RNA Interference-based Drugs
6.2.2 Stringent Regulations and Long Product Approval Process
6.2.3 Unstable Potentially Immunogenic Nature of RNA
6.3 Market Trends
6.3.1 Rapid Clinical-developments in RNAi Therapeutics for Cancer Application
Table 80: Current Clinical Status of RNAi Therapeutics for Cancer Treatment
6.3.2 RNA Interference Therapeutics for Cardiac Regeneration
6.3.3 Physiologically Based Pharmacokinetic (PBPK) Modeling of RNAi Therapeutics
6.3.4 Folate Receptor-Mediated siRNA Delivery
6.3.5 Growing Focus on Personalized Medicines
6.3.6 New AI Technologies in RNAi Therapeutics Market
7. Competitive Landscape
7.1 Global RNAi Therapeutics Market Players: A Financial Comparison
Table 81: Global RNAi Therapeutics Market Players: A Financial Comparison; 2020/2021
7.2 Global RNAi Therapeutics Market Players: Technology Comparison
Table 82: Global RNAi Therapeutics Market Players: Technology Comparison
7.3 Global RNAi Therapeutics Market Players: Product & Services Comparison
Table 83: Global RNAi Therapeutics Market Players: Product & Services Comparison
7.4 Global RNAi Therapeutics Market Players: Research & Development Expenses Comparison
Table 84: Global RNAi Therapeutics Market Players: Research & Development Expenses Comparison; 2017-2020 (US$ Million)
8. Company Profiles
8.1 Moderna Inc.
8.1.1 Business Overview
8.1.2 Financial Overview
Table 85: Moderna Inc. Total Revenues; 2017-2021 (US$ Million)
8.1.3 Business Strategy
8.2 Alnylam Pharmaceuticals Inc.
8.2.1 Business Overview
8.2.2 Financial Overview
Table 86: Alnylam Pharmaceuticals Inc. Revenue; 2017-2021 (US$ Million)
Table 87: Alnylam Pharmaceuticals Inc. Net Product Revenue by Product; 2021 (Percentage, %)
Table 88: Alnylam Pharmaceuticals Inc. Net Product Revenue by Region; 2021 (Percentage, %)
8.2.3 Business Strategy
8.3 Ionis Pharmaceuticals Inc.
8.3.1 Business Overview
8.3.2 Financial Overview
Table 89: Ionis Pharmaceuticals Inc. Revenue; 2017-2021 (US$ Million)
8.3.3 Business Strategy
8.4 Silence Therapeutics Inc.
8.4.1 Business Overview
8.4.2 Financial Overview
Table 90: Silence Therapeutics Inc. Total Revenue; 2016-2020 (US$ Million)
Table 91: Silence Therapeutics Inc. Total Revenue by Region; 2020 (Percentage, %)
8.4.3 Business Strategy

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