Global RNAi Therapeutics Market (by Molecule Type, Application, End-User & Region): Insights & Forecast with Potential Impact of COVID-19 (2024-2028)

Global RNAi Therapeutics Market (by Molecule Type, Application, End-User & Region): Insights & Forecast with Potential Impact of COVID-19 (2024-2028)


The global RNAi therapeutics market is expected to record a value of US$1.26 billion in 2028, progressing at a CAGR of 10.02%, over the period 2024-2028. Factors such as rising utilization in oncology pharmaceuticals, accelerating growth rates of infectious diseases, enlarging geriatric population, increasing prevalence of neurodegenerative disorders and progress in collaborations and associated deals in RNAi therapeutics. However, the market growth would be challenged by complexity associated with the drug delivery of RNAi therapeutics, high development cost of RNA interference-based therapeutics and stringent regulatory requirements. A few notable trends include growing popularity of personalized medicine, surging preference RNAi therapeutics as an alternative for HTS & keloids treatment and escalating applications in molecular diagnostics.

The global market has been segmented on the basis of molecule type, application and end-user. On the basis of molecule type, the global market can be bifurcated into small interfering RNAs (siRNAs) and microRNAs (miRNAs). According to applications, the market can be divided into oncology, respiratory disorders, neurological disorders, liver disorders, autoimmune disorders and other disorders. Whereas, the global RNAi therapeutics market is split into research & academic laboratories and hospitals & diagnostic laboratories, in terms of end-user.

The fastest growing regional market is North America owing to increasing prevalence of chronic conditions, rising investments for development of RNAi therapeutics along with growing number of research activities for RNA-based therapeutics in the region. Further, the COVID-19 pandemic has positively impacted the market due to the growing relevance of RNA-based investigations as well as increasing funding for R&D activities.

Scope of the report:
  • The report provides a comprehensive analysis of the global RNAi therapeutics market segmented on the basis of molecule type, application, end-user and region, with potential impact of COVID-19.
  • The major regional and country markets (North America, Europe, Asia Pacific and RoW) have been analyzed.
  • The market dynamics such as growth drivers, market trends and challenges are analyzed in-depth.
  • The competitive landscape of the market, along with the company profiles of leading players (Sanofi S.A., Alnylam Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., Arbutus Biopharma Corporation, Benitec Biopharma Ltd., and Sirnaomics, Ltd.) are also presented in detail.
Key Target Audience:
  • RNAi Therapeutics Service/Equipment Providers and Distributors
  • Pharmaceutical, Biopharmaceutical & Biotechnological Companies
  • Research and Development (R&D) Organizations
  • End Users
  • Government Bodies & Regulating Authorities


1. Market Overview
1.1 Introduction
1.2 Different Classes of RNA Therapeutics
Table 1: Schematic Illustration of Different Classes of RNA Therapeutics
1.3 Major Pathways of RNAi
Table 2: RNA Interference Therapeutic Process
1.4 Various Small RNA Isoforms related to RNAi
Table 3: Various Small RNA Isoforms related to RNAi
1.5 Key Features of RNAi Therapeutics
Table 4: Key Features of RNAi Therapeutics
1.6 Comparison of RNAi Treatments against Other Treatment Classes
Table 5: Comparison of RNAi Treatments against Other Treatment Classes
1.7 Platform Comparison of RNAi Therapeutics
Table 6: Platform Comparison of RNAi Therapeutics
1.8 Applications of RNAi in Vivo
Table 7: Applications of RNAi in Vivo
2. Impact of COVID-19
2.1 Rapid Spread of Coronavirus
Table 8: Number of Cumulative Cases of Coronavirus (COVID-19) Worldwide (2020)
2.2 Growth in COVID-19 R&D Funding
Table 9: COVID-19 R&D Funding by Major Countries (2020)
2.3 RNA Vaccine Development for COVID-19
Table 10: mRNA Vaccine in Development for COVID-19
3. Global Market Analysis
3.1 Global RNAi Therapeutics Market by Value
Table 11: Global RNAi Therapeutics Market by Value (2019-2023)
3.2 Global RNAi Therapeutics Market Forecast by Value
Table 12: Global RNAi Therapeutics Market Forecast by Value (2024-2028)
3.3 Global RNAi Therapeutics Market by Molecule Type
Table 13: Global RNAi Therapeutics Market by Molecule Type (2023)
3.3.1 Global Small Interfering RNA (siRNA) Therapeutics Market by Value
Table 14: Global Small Interfering RNA (siRNA) Therapeutics Market by Value (2019-2023)
3.3.2 Global Small Interfering RNA (siRNA) Therapeutics Market Forecast by Value
Table 15: Global Small Interfering RNA (siRNA) Therapeutics Market Forecast by Value (2024-2028)
3.3.3 Global Small Interfering RNA (siRNA) Therapeutics Market by Type
Table 16: Global Small Interfering RNA (siRNA) Therapeutics Market by Type (2023)
3.3.4 Global Small Interfering RNA (siRNA) Therapeutics Type Market by Value
Table 17: Global Small Interfering RNA (siRNA) Therapeutics Type Market by Value (2019-2023)
3.3.5 Global Small Interfering RNA (siRNA) Therapeutics Type Market Forecast by Value
Table 18: Global Small Interfering RNA (siRNA) Therapeutics Type Market Forecast by Value (2024-2028)
3.3.6 Global MicroRNA (miRNA) Therapeutics Market by Value
Table 19: Global MicroRNA (miRNA) Therapeutics Market by Value (2019-2023)
3.3.7 Global MicroRNA (miRNA) Therapeutics Market Forecast by Value
Table 20: Global MicroRNA (miRNA) Therapeutics Market Forecast by Value (2024-2028)
3.4 Global RNAi Therapeutics Market by Application
Table 21: Global RNAi Therapeutics Market by Application (2023)
3.4.1 Global RNAi Therapeutics Application Market by Value
Table 22: Global RNAi Therapeutics Application Market by Value (2019-2023)
3.4.2 Global RNAi Therapeutics Product Market Forecast by Value
Table 23: Global RNAi Therapeutics Product Market Forecast by Value (2024-2028)
3.5 Global RNAi Therapeutics Market by End-Users
Table 24: Global RNAi Therapeutics Market by End-Users (2023)
3.5.1 Global RNAi Therapeutics End-User Market by Value
Table 25: Global RNAi Therapeutics End-User Market by Value (2019-2023)
3.5.2 Global RNAi Therapeutics End-User Market Forecast by Value
Table 26: Global RNAi Therapeutics End-User Market Forecast by Value (2024-2028)
3.6 Global RNAi Therapeutics Market by Region
Table 27: Global RNAi Therapeutics Market by Region (2023)
4. Regional Market Analysis
4.1 North America
4.1.1 North America RNAi Therapeutics Market by Value
Table 28: North America RNAi Therapeutics Market by Value (2019-2023)
4.1.2 North America RNAi Therapeutics Market Forecast by Value
Table 29: North America RNAi Therapeutics Market Forecast by Value (2024-2028)
4.1.3 The U.S. RNAi Therapeutics Market Forecast by Value
Table 30: The U.S. RNAi Therapeutics Market Forecast by Value (2021-2028)
4.2 Europe
4.2.1 Europe RNAi Therapeutics Market by Value
Table 31: Europe RNAi Therapeutics Market by Value (2019-2023)
4.2.2 Europe RNAi Therapeutics Market Forecast by Value
Table 32: Europe RNAi Therapeutics Market Forecast by Value (2024-2028)
4.3 Asia Pacific
4.3.1 Asia Pacific RNAi Therapeutics Market by Value
Table 33: Asia Pacific RNAi Therapeutics Market by Value (2019-2023)
4.3.2 Asia Pacific RNAi Therapeutics Market Forecast by Value
Table 34: Asia Pacific RNAi Therapeutics Market Forecast by Value (2024-2028)
4.4 RoW
4.4.1 RoW RNAi Therapeutics Market by Value
Table 35: RoW RNAi Therapeutics Market by Value (2019-2023)
4.4.2 RoW RNAi Therapeutics Market Forecast by Value
Table 36: RoW RNAi Therapeutics Market Forecast by Value (2024-2028)
5. Market Dynamics
5.1 Growth Drivers
5.1.1 Rising Utilization in Oncology Pharmaceuticals
Table 37: Oncology Pharmaceuticals Market in the U.S. and China (2020-2030)
5.1.2 Accelerating Growth Rates of Infectious Diseases
Table 38: Global Growth Rate of Infectious Diseases Forecast (2017-2023)
5.1.3 Enlarging Geriatric Population
Table 39: Global Population 65 Years and Above (2017-2023)
5.1.4 Increasing Prevalence of Neurodegenerative Disorders
Table 40: Worldwide Projections of Alzheimer’s Disease Prevalence (2015-2040)
5.1.5 Progress in Collaborations & Associated Deals in RNAi Therapeutics
Table 41: Deals in RNAi Therapeutics (2020-2023)
5.1.6 Expanding Research & Development Activities
5.2 Key Trends and Developments
5.2.1 Growing Popularity of Personalized Medicine
Table 42: Global Personalized Medicine Market (2018-2023)
5.2.2 Surging Preference as an Alternative for HTS & Keloids Treatment
Table 43: Market Size of Hypertrophic Scars (HTS) & Keloids Treatments (2020-2030)
5.2.3 Escalating Applications in Molecular Diagnostics
Table 44: Global Molecular Diagnostics Market (2021-2026)
5.2.4 Development of RNAi Therapeutics
Table 45: Approved RNAi Therapeutics (2019-2023)
5.3 Challenges
5.3.1 Complexity Associated with the Delivery of RNAi Therapeutics
5.3.2 High Development Cost of RNA Interference-Based Therapeutics
5.3.3 Stringent Regulatory Requirements
6. Company Profiles
6.1 Sanofi S.A. (Genzyme Corporation)
6.1.1 Business Overview
6.2 Alnylam Pharmaceuticals Inc.
6.2.1 Business Overview
6.3 Arrowhead Pharmaceuticals Inc.
6.3.1 Business Overview
6.4 Arbutus Biopharma Corporation
6.4.1 Business Overview
6.5 Benitec Biopharma Ltd.
6.5.1 Business Overview
6.6 Sirnaomics, Ltd.
6.6.1 Business Overview

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook
Cookie Settings