HIV-1 Infection – Pipeline Review, H2 2012

Published by: Global Markets Direct

Published: Aug. 31, 2012 - 287 Pages


Table of Contents

Introduction
Global Markets Direct Report Coverage
HIV-1 Infection Overview
Therapeutics Development
An Overview of Pipeline Products for HIV-1 Infection
HIV-1 Infection Therapeutics under Development by Companies
HIV-1 Infection Therapeutics under Investigation by Universities/Institutes
Late Stage Products
Comparative Analysis
Mid Clinical Stage Products
Comparative Analysis
Early Clinical Stage Products
Comparative Analysis
Discovery and Pre-Clinical Stage Products
Comparative Analysis
HIV-1 Infection Therapeutics – Products under Development by Companies
HIV-1 Infection Therapeutics – Products under Investigation by Universities/Institutes
Companies Involved in HIV-1 Infection Therapeutics Development
Bristol-Myers Squibb Company
Johnson & Johnson
Abbott Laboratories
GlaxoSmithKline plc
Inovio Biomedical Corporation
Gilead Sciences, Inc.
Merck & Co., Inc.
United Biomedical, Inc.
Aphios Corporation
Pfizer Inc.
Avexa Limited
Koronis Pharmaceuticals, Inc.
Alfacell Corporation
Geron Corporation
GeoVax Labs, Inc.
ConjuChem Biotechnologies Inc.
Critical Outcome Technologies Inc.
Takara Bio Inc.
Functional Genetics, Inc.
BioClonetics Incorporated
Nutri Pharma ASA
Vironova AB
Argos Therapeutics, Inc.
Myriad Pharmaceuticals, Inc.
GeneCure LLC
Tobira Therapeutics, Inc.
ViiV Healthcare
RFS Pharma, LLC
Vichem Chemie Research Ltd.
HIV-1 Infection – Therapeutics Assessment
Assessment by Monotherapy Products
Assessment by Combination Products
Assessment by Route of Administration
Assessment by Molecule Type
Drug Profiles
1265744 - Drug Profile
MPI-461359 - Drug Profile
pGA2/JS7 DNA Vaccine + Recombinant Modified Vaccinia Ankara/HIV62B Vaccine - Drug Profile
Amdoxovir - Drug Profile
TBR-652 - Drug Profile
AGS-004 - Drug Profile
Apricitabine - Drug Profile
Raltegravir + Tenofovir + Lamivudine - Drug Profile
Tenofovir + Emtricitabine + Efavirenz - Drug Profile
Autologous HIV-1 ApB DC Vaccine - Drug Profile
Lopinavir + Ritonavir - Drug Profile
Dapivirine Ring - Drug Profile
Zidovudine + Lamivudine + Nevirapine - Drug Profile
Truvada + Darunavir + Ritonavir + Maraviroc + Raltegravir - Drug Profile
Gardasil - Drug Profile
Dendritic Cell Vaccine + GM-CSF + Interferon Alpha - Drug Profile
mRNA-Transfected Autologous Dendritic Cells - Drug Profile
MVA.HIVA Vaccine - Drug Profile
Etravirine + Nucleoside + Nucleotide Reverse Transcriptase Inhibitors - Drug Profile
Emtricitabine + Tenofovir Disoproxil Fumarate + Ritonavir + Atazanavir - Drug Profile
Emtricitabine + Tenofovir Disoproxil Fumarate + Raltegravir - Drug Profile
Emtricitabine + Tenofovir Disoproxil Fumarate + Darunavir + Ritonavir - Drug Profile
VRC-HIVADV014-00-VP - Drug Profile
Stavudine + Lamivudine + Abacavir - Drug Profile
Emtricitabine + Tenofovir - Drug Profile
Tenofovir - Drug Profile
Stavudine + Lamivudine + Nevirapine - Drug Profile
Abacavir + Lamivudine + Nevirapine - Drug Profile
Zidovudine + Lamivudine + Abacavir - Drug Profile
Emend - Drug Profile
Didanosine + Abacavir + Kaletra - Drug Profile
Zidovudine + Lamivudine + Kaletra - Drug Profile
Lamivudine + Didanosine + Efavirenz - Drug Profile
Lamivudine + Recombinant Hepatitis B Surface Antigen - Drug Profile
Raltegravir + Lopinavir + Ritonavir - Drug Profile
Isentress + Kaletra - Drug Profile
Vacc-4x - Drug Profile
Ad35-GRIN/ENV HIV Vaccine - Drug Profile
VRC-HIVDNA-016-00-VP + VRCHIVADV014-00-VP - Drug Profile
Atazanavir + Raltegravir + Lamivudine - Drug Profile
Atazanavir + Raltegravir + Emtricitabine - Drug Profile
Lopinavir + Ritonavir + Zidovudine - Drug Profile
Abacavir + Zidovudine - Drug Profile
BMS-663068 - Drug Profile
BMS-663068 + Ritonavir - Drug Profile
Darunavir + Ritonavir - Drug Profile
Raltegravir + Darunavir + Etravirine + NRTIs + Enfuvirtide - Drug Profile
TUTI-16 - Drug Profile
Isentress + Celsentri + Prezista + Norvir + Truvada - Drug Profile
TMC310911 + Ritonavir - Drug Profile
KP-1461 - Drug Profile
Atazanavir + Ritonavir + Abacavir + Lamivudine - Drug Profile
PENNVAX-B DNA Vaccine - Drug Profile
EP HIV-1043 - Drug Profile
EP HIV-1043 + EP HIV-1090 - Drug Profile
EP HIV-1090 - Drug Profile
rAd5 env A + rAd5 env B - Drug Profile
GTU-MultiHIV B Clade Vaccine + Interleukin-2 + GM-CSF + Growth Hormone - Drug Profile
PENNVAX-B + GENEVAX IL-12-4532 - Drug Profile
PENNVAX-B + GENEVAX IL-12-4532 - Drug Profile
SAAVI DNA-C2 Vaccine + SAAVI MVA-C Vaccine - Drug Profile
Kaletra - Drug Profile
Enfuvirtide + Raltegravir + Darunavir + Tipranavir + Etravirine + Maraviroc - Drug Profile
Viread + Aluvia - Drug Profile
Truvada + Nevirapine - Drug Profile
Truvada + Zidovudine - Drug Profile
ALVAC-HIV vCP1521 - Drug Profile
MVA.HIVconsv - Drug Profile
TBC-M4 - Drug Profile
AD100-GP96IG-HLA A1 Vaccine - Drug Profile
ChAdV63.HIVconsv + pSG2.HIVconsv + MVA.HIVconsv - Drug Profile
Fuzeon + Truvada + Kaletra - Drug Profile
rAd35 Env A - Drug Profile
rAd35 Env A + rAd5 Env A - Drug Profile
rAd5 Env A - Drug Profile
Tenofovir + Emtricitabine - Drug Profile
GS-7340 - Drug Profile
Isentress + Tenofovir + Lamivudine - Drug Profile
HIV gp120/NefTat/AS02A Vaccine - Drug Profile
ART Regimen + Raltegravir + Maraviroc - Drug Profile
KD-247 - Drug Profile
HIV-1 Integrase Inhibitor Program - Drug Profile
ART Regimen + Raltegravir + Maraviroc + Interleukin-7 - Drug Profile
Zinc Supplementation - Drug Profile
Intelence + Truvada - Drug Profile
Autologous CD4-ZETA Gene Modified T Cells + Interleukin-2 - Drug Profile
Intelence + Ritonavir + Atazanavir + NRTI - Drug Profile
UB-421 - Drug Profile
HIV-1 Drug Development Programme - Drug Profile
TAT0002 - Drug Profile
Celsentri + Antiretroviral Therapy - Drug Profile
UK-453061 + Tenofovir DF + Emtricitabine - Drug Profile
DACHIV - Drug Profile
Lamivudine + Tenofovir + Atazanavir + Ritonavir - Drug Profile
GSK732462 - Drug Profile
572-Trii - Drug Profile
Antiretroviral Therapy + Pegintron - Drug Profile
TBR 652 + Truvada - Drug Profile
APH-0812 - Drug Profile
Reyataz + Cobicistat - Drug Profile
Cobicistat + Prezista - Drug Profile
Vorinostat - Drug Profile
HIV-1 Therapeutic Vaccine - Drug Profile
Leukothera - Drug Profile
BMS-663068 + Raltegravir + Tenofovir - Drug Profile
KP-1212 - Drug Profile
Recombinant Amphinase 2 - Drug Profile
HIVAX - Drug Profile
Lersivirine + Darunavir + Ritonavir + NRTI - Drug Profile
MK-1439 - Drug Profile
CDK9 Inhibitors - Drug Profile
BMS-986001 + Sustiva + Lamivudine - Drug Profile
Etravirine - Drug Profile
VAC-3S - Drug Profile
MazF-Based HIV-1 Gene Therapy - Drug Profile
AFO18–CAF01 Vaccine - Drug Profile
GTU-MultiHIV B + LIPO-5 - Drug Profile
Rifaximin - Drug Profile
FGI-111 Program - Drug Profile
CLONE 3 - Drug Profile
Atazanavir + Lamivudine + Ritonavir - Drug Profile
HIV-1 Infection Therapeutics – Drug Profile Updates
HIV-1 Infection Therapeutics – Discontinued Products
HIV-1 Infection Therapeutics - Dormant Products
HIV-1 Infection – Product Development Milestones
Featured News & Press Releases
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Number of Products Under Development for HIV-1 Infection, H2 2012
Products under Development for HIV-1 Infection – Comparative Analysis, H2 2012
Number of Products under Development by Companies, H2 2012
Number of Products under Development by Companies, H2 2012 (Contd..1)
Number of Products under Development by Companies, H2 2012 (Contd..2)
Number of Products under Investigation by Universities/Institutes, H2 2012
Number of Products under Investigation by Universities/Institutes, H2 2012 (Contd..1)
Comparative Analysis by Late Stage Development, H2 2012
Comparative Analysis by Mid Clinical Stage Development, H2 2012
Comparative Analysis by Early Clinical Stage Development, H2 2012
Comparative Analysis by Discovery and Pre-Clinical Stage Development, H2 2012
Products under Development by Companies, H2 2012
Products under Development by Companies, H2 2012 (Contd..1)
Products under Development by Companies, H2 2012 (Contd..2)
Products under Investigation by Universities/Institutes, H2 2012
Products under Investigation by Universities/Institutes, H2 2012 (Contd..1)
Products under Investigation by Universities/Institutes, H2 2012 (Contd..2)
Products under Investigation by Universities/Institutes, H2 2012 (Contd..3)
Products under Investigation by Universities/Institutes, H2 2012 (Contd..4)
Bristol-Myers Squibb Company, H2 2012
Johnson & Johnson, H2 2012
Abbott Laboratories, H2 2012
GlaxoSmithKline plc, H2 2012
Inovio Biomedical Corporation, H2 2012
Gilead Sciences, Inc., H2 2012
Merck & Co., Inc., H2 2012
United Biomedical, Inc., H2 2012
Aphios Corporation, H2 2012
Pfizer Inc., H2 2012
Avexa Limited, H2 2012
Koronis Pharmaceuticals, Inc., H2 2012
Alfacell Corporation, H2 2012
Geron Corporation, H2 2012
GeoVax Labs, Inc., H2 2012
ConjuChem Biotechnologies Inc., H2 2012
Critical Outcome Technologies Inc., H2 2012
Takara Bio Inc., H2 2012
Functional Genetics, Inc., H2 2012
BioClonetics Incorporated, H2 2012
Nutri Pharma ASA, H2 2012
Vironova AB, H2 2012
Argos Therapeutics, Inc., H2 2012
Myriad Pharmaceuticals, Inc., H2 2012
GeneCure LLC, H2 2012
Tobira Therapeutics, Inc., H2 2012
ViiV Healthcare, H2 2012
RFS Pharma, LLC, H2 2012
Vichem Chemie Research Ltd., H2 2012
Assessment by Monotherapy Products, H2 2012
Assessment by Combination Products, H2 2012
Assessment by Stage and Route of Administration, H2 2012
Assessment by Stage and Molecule Type, H2 2012
HIV-1 Infection Therapeutics – Drug Profile Updates
HIV-1 Infection Therapeutics – Discontinued Products
HIV-1 Infection Therapeutics – Discontinued Products (Contd..1)
HIV-1 Infection Therapeutics – Dormant Products
HIV-1 Infection Therapeutics – Dormant Products (Contd..1)
HIV-1 Infection Therapeutics – Dormant Products (Contd..2)
HIV-1 Infection Therapeutics – Dormant Products (Contd..3)
HIV-1 Infection Therapeutics – Dormant Products (Contd..4)
HIV-1 Infection Therapeutics – Dormant Products (Contd..5)
HIV-1 Infection Therapeutics – Dormant Products (Contd..6)
HIV-1 Infection Therapeutics – Dormant Products (Contd..7)
HIV-1 Infection Therapeutics – Dormant Products (Contd..8)
HIV-1 Infection Therapeutics – Dormant Products (Contd..9)
HIV-1 Infection Therapeutics – Dormant Products (Contd..10)
List of Figures
Number of Products under Development for HIV-1 Infection, H2 2012
Products under Development for HIV-1 Infection – Comparative Analysis, H2 2012
Products under Development by Companies, H2 2012
Products under Investigation by Universities/Institutes, H2 2012
Late Stage Products, H2 2012
Mid Clinical Stage Products, H2 2012
Early Clinical Stage Products, H2 2012
Discovery and Pre-Clinical Stage Products, H2 2012
Assessment by Monotherapy Products, H2 2012
Assessment by Combination Products, H2 2012
Assessment by Route of Administration, H2 2012
Assessment by Stage and Route of Administration, H2 2012
Assessment by Molecule Type, H2 2012
Assessment by Stage and Molecule Type, H2 2012

Abstract

HIV-1 Infection – Pipeline Review, H2 2012

Summary

Global Markets Direct’s, 'HIV-1 Infection - Pipeline Review, H2 2012', provides an overview of the HIV-1 Infection therapeutic pipeline. This report provides information on the therapeutic development for HIV-1 Infection, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for HIV-1 Infection. 'HIV-1 Infection - Pipeline Review, H2 2012' is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope
  • A snapshot of the global therapeutic scenario for HIV-1 Infection.
  • A review of the HIV-1 Infection products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • Coverage of products based on various stages of development ranging from discovery till registration stages.
  • A feature on pipeline projects on the basis of monotherapy and combined therapeutics.
  • Coverage of the HIV-1 Infection pipeline on the basis of route of administration and molecule type.
  • Profiles of late-stage pipeline products featuring sections on product description, mechanism of action and research & development progress.
  • Key discontinued pipeline projects.
  • Latest news and deals relating to the products.
Reasons to buy
  • Identify and understand important and diverse types of therapeutics under development for HIV-1 Infection.
  • Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive advantage.
  • Plan mergers and acquisitions effectively by identifying players with the most promising pipeline.
  • Devise corrective measures for pipeline projects by understanding HIV-1 Infection pipeline depth and focus of HIV-1 Infection therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline.


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