Arthritis – Pipeline Review, H2 2012

Published by: Global Markets Direct

Published: Jul. 31, 2012 - 133 Pages


Table of Contents

Introduction
Global Markets Direct Report Coverage
Arthritis Overview
Therapeutics Development
An Overview of Pipeline Products for Arthritis
Arthritis Therapeutics under Development by Companies
Arthritis Therapeutics under Investigation by Universities/Institutes
Late Stage Products
Comparative Analysis
Mid Clinical Stage Products
Comparative Analysis
Early Clinical Stage Products
Comparative Analysis
Discovery and Pre-Clinical Stage Products
Comparative Analysis
Arthritis Therapeutics – Products under Development by Companies
Arthritis Therapeutics – Products under Investigation by Universities/Institutes
Companies Involved in Arthritis Therapeutics Development
Baxter International Inc.
F. Hoffmann-La Roche Ltd.
Seikagaku Corporation
Amgen Inc.
Eli Lilly and Company
GlaxoSmithKline plc
Cytokine PharmaSciences, Inc.
Celltrion, Inc.
Sylentis
Pfizer Inc.
UCB Group
Celgene Corporation
Bone Medical Limited
Can-Fite BioPharma Ltd.
CSL Limited
Oscotec Inc.
AnaMar Medical AB
CREABILIS Therapeutics S.r.l.
Alder Biopharmaceuticals Inc.
PLx Pharma Inc.
Cempra Pharmaceuticals, Inc.
NasVax Ltd.
Centocor Ortho Biotech, Inc.
RNL BIO Co., Ltd.
Arthritis – Therapeutics Assessment
Assessment by Monotherapy Products
Assessment by Combination Products
Assessment by Route of Administration
Assessment by Molecule Type
Drug Profiles
CSL324 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
AMG 827 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
LY2439821 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Tofacitinib - Drug Profile
Product Description
Mechanism of Action
R&D Progress
CC-10004 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Cimzia - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Stelara - Drug Profile
Product Description
Mechanism of Action
R&D Progress
ALD-518 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
GLPG0555 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
CEM-102 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
CF602 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Piroxicam - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Meloxicam - Drug Profile
Product Description
Mechanism of Action
R&D Progress
PL 5100 Diclofenac - Drug Profile
Product Description
Mechanism of Action
R&D Progress
RG4934 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Orfadin - Drug Profile
Product Description
Mechanism of Action
R&D Progress
CT340 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
RO5310074 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Drug For Arthritis - Drug Profile
Product Description
Mechanism of Action
R&D Progress
MIF Inhibitors - Drug Profile
Product Description
Mechanism of Action
R&D Progress
CT-P05 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
DIS-BIO-OA01 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Core Targeted Therapy - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Humanized Antibody Conjugate - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Anti-aCD3 Mab - Drug Profile
Product Description
Mechanism of Action
R&D Progress
BN005 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
BN008 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
GLPG0778 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
HZN-602 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
5-HT2 Receptor Antagonist - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Anti-MIF Antibody - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Jointstem - Drug Profile
Product Description
Mechanism of Action
R&D Progress
OCT-SG815 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
IL-23 Receptor Antagonists - Drug Profile
Product Description
Mechanism of Action
R&D Progress
SYK Inhibitors - Drug Profile
Product Description
Mechanism of Action
R&D Progress
ADAMTS-5 Inhibitors - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Selected Activated T Cell Death Inducers - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Selegiline + NSAIDs - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Anti-MIF Receptor Technology Platform - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Arthritis Therapeutics – Drug Profile Updates
Arthritis Therapeutics – Discontinued Products
Arthritis Therapeutics - Dormant Products
Arthritis – Product Development Milestones
Featured News & Press Releases
Jul 12, 2012: Celgene's Apremilast Achieves Statistical Significance For Primary Endpoint Of First Phase III Study In Patients With Psoriatic Arthritis
Jun 21, 2012: CHMP Adopts Positive Opinion Recommending Variation To Terms Of Marketing Authorization For Enbrel
Jun 21, 2012: CHMP Adopts Positive Opinion Recommending Variation To Terms Of Marketing Authorization For Enbrel
Jun 06, 2012: UCB Presents Results From RAPID-PsA Study Of Certolizumab Pegol At EULAR Annual European Congress Of Rheumatology
Jun 06, 2012: Savient Pharma Presents New Analysis From Phase III Study Of KRYSTEXXA At EULAR 2012
Jun 05, 2012: Janssen Reports Positive Data From Phase III Study Of STELARA For Treatment Of Psoriatic Arthritis At EULAR Annual Congress
May 01, 2012: Pfizer Settles Celebrex Lawsuit With Brigham Young University
Feb 16, 2012: UCB Announces Positive Top-Line Results For Cimzia In Psoriatic Arthritis
Jan 26, 2012: Medipost Announces Export Of Stem Cell Arthritis Drug
Dec 19, 2011: Galapagos Achieves Clinical Proof-Of-Mechanism Milestone In GSK Alliance
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Number of Products Under Development for Arthritis, H2 2012
Products under Development for Arthritis – Comparative Analysis, H2 2012
Number of Products under Development by Companies, H2 2012
Number of Products under Development by Companies, H2 2012 (Contd..1)
Number of Products under Investigation by Universities/Institutes, H2 2012
Comparative Analysis by Late Stage Development, H2 2012
Comparative Analysis by Mid Clinical Stage Development, H2 2012
Comparative Analysis by Early Clinical Stage Development, H2 2012
Comparative Analysis by Discovery and Pre-Clinical Stage Development, H2 2012
Products under Development by Companies, H2 2012
Products under Investigation by Universities/Institutes, H2 2012
Baxter International Inc., H2 2012
F. Hoffmann-La Roche Ltd., H2 2012
Seikagaku Corporation, H2 2012
Amgen Inc., H2 2012
Eli Lilly and Company, H2 2012
GlaxoSmithKline plc, H2 2012
Cytokine PharmaSciences, Inc., H2 2012
Celltrion, Inc., H2 2012
Sylentis, H2 2012
Pfizer Inc., H2 2012
UCB Group, H2 2012
Celgene Corporation, H2 2012
Bone Medical Limited, H2 2012
Can-Fite BioPharma Ltd., H2 2012
CSL Limited, H2 2012
Oscotec Inc., H2 2012
AnaMar Medical AB, H2 2012
CREABILIS Therapeutics S.r.l., H2 2012
Alder Biopharmaceuticals Inc., H2 2012
PLx Pharma Inc., H2 2012
Cempra Pharmaceuticals, Inc., H2 2012
NasVax Ltd., H2 2012
Centocor Ortho Biotech, Inc., H2 2012
RNL BIO Co., Ltd., H2 2012
Assessment by Monotherapy Products, H2 2012
Assessment by Combination Products, H2 2012
Assessment by Stage and Route of Administration, H2 2012
Assessment by Stage and Molecule Type, H2 2012
Arthritis Therapeutics – Drug Profile Updates
Arthritis Therapeutics – Discontinued Products
Arthritis Therapeutics – Dormant Products
List of Figures
Number of Products under Development for Arthritis, H2 2012
Products under Development for Arthritis – Comparative Analysis, H2 2012
Products under Development by Companies, H2 2012
Products under Investigation by Universities/Institutes, H2 2012
Late Stage Products, H2 2012
Mid Clinical Stage Products, H2 2012
Early Clinical Stage Products, H2 2012
Discovery and Pre-Clinical Stage Products, H2 2012
Assessment by Monotherapy Products, H2 2012
Assessment by Combination Products, H2 2012
Assessment by Route of Administration, H2 2012
Assessment by Stage and Route of Administration, H2 2012
Assessment by Molecule Type, H2 2012
Assessment by Stage and Molecule Type, H2 2012

Abstract

Arthritis – Pipeline Review, H2 2012

Summary

Global Markets Direct’s, 'Arthritis - Pipeline Review, H2 2012', provides an overview of the Arthritis therapeutic pipeline. This report provides information on the therapeutic development for Arthritis, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Arthritis. 'Arthritis - Pipeline Review, H2 2012' is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope
  • A snapshot of the global therapeutic scenario for Arthritis.
  • A review of the Arthritis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • Coverage of products based on various stages of development ranging from discovery till registration stages.
  • A feature on pipeline projects on the basis of monotherapy and combined therapeutics.
  • Coverage of the Arthritis pipeline on the basis of route of administration and molecule type.
  • Profiles of late-stage pipeline products featuring sections on product description, mechanism of action and research & development progress.
  • Key discontinued pipeline projects.
  • Latest news and deals relating to the products.
Reasons to buy
  • Identify and understand important and diverse types of therapeutics under development for Arthritis.
  • Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive advantage.
  • Plan mergers and acquisitions effectively by identifying players with the most promising pipeline.
  • Devise corrective measures for pipeline projects by understanding Arthritis pipeline depth and focus of Arthritis therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline.


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