Alzheimer's Disease - Pipeline Review, Q1 2011

Published by: Global Markets Direct

Published: Feb. 28, 2011 - 153 Pages


Table of Contents

Introduction
Global Markets Direct Report Coverage
Alzheimer's Disease Overview
Therapeutics Development
An Overview of Pipeline Products for Alzheimer's Disease
Alzheimer's Disease Therapeutics under Development by Companies
Alzheimer's Disease Therapeutics under Investigation by Universities/Institutes
Late Stage Products
Comparative Analysis
Mid Clinical Stage Products
Comparative Analysis
Early Clinical Stage Products
Comparative Analysis
Discovery and Pre-Clinical Stage Products
Comparative Analysis
Companies Involved in Alzheimer's Disease Therapeutics Development
Bristol-Myers Squibb Company
DURECT Corporation
Johnson & Johnson
Boehringer Ingelheim GmbH
F. Hoffmann-La Roche Ltd.
Abbott Laboratories
NsGene A/S
Sanofi-Aventis
AstraZeneca PLC
Eli Lilly and Company
GlaxoSmithKline plc
Antigenics, Inc.
Daiichi Sankyo Company, Ltd
Merck & Co., Inc.
United Biomedical, Inc.
Dainippon Sumitomo Pharma Co., Ltd.
Applied NeuroSolutions, Inc.
Myriad Genetics, Inc.
Takeda Pharmaceutical Company Limited
ExonHit Therapeutics SA
Plexxikon Inc.
Mochida Pharmaceutical Co., Ltd.
Avineuro Pharmaceuticals, Inc.
Nanotherapeutics, Inc.
Senexis Limited
Novartis AG
Samyang Corporation
EnVivo Pharmaceuticals
DECODON GmbH
Astellas Pharma Inc.
Chiesi Farmaceutici SpA
Daewoong Pharmaceutical Co., Ltd.
Eisai Co., Ltd.
Elan Corporation, plc
H Lundbeck A/S
Octapharma AG
Ono Pharmaceutical Co., Ltd.
Orion Corporation
Pfizer Inc.
Sunesis Pharmaceuticals, Inc.
Teva Pharmaceutical Industries Limited
Toyama Chemical Co. Ltd
Sandoz Inc.
ENKAM Pharmaceuticals A/S
Astex Therapeutics Limited
Addex Pharmaceuticals
Evotec Aktiengesellschaft
Anavex Life Sciences Corp.
Amicus Therapeutics, Inc.
Idera Pharmaceuticals, Inc.
Ligand Pharmaceuticals Incorporated
BELLUS Health Inc
Medivir AB
ReGenX Biosciences, LLC
Neuren Pharmaceuticals Limited
Neuro-Hitech, Inc.
Cortex Pharmaceuticals, Inc.
Critical Outcome Technologies Inc.
ACADIA Pharmaceuticals Inc.
Medivation, Inc.
ProteoTech, Inc.
Theratechnologies Inc.
Phytopharm Plc
SYGNIS Pharma AG
Prana Biotechnology Limited
Hanall Pharmaceutical Co., Ltd.
SCOLR Pharma, Inc.
Transition Therapeutics Inc.
Allon Therapeutics Inc.
Neurim Pharmaceuticals (1991) Ltd.
Samaritan Pharmaceuticals, Inc.
Theravance, Inc.
Resverlogix Corp.
Suven Life Sciences Ltd.
Galapagos NV
MediPost Co., Ltd.
Sucampo Pharmaceuticals, Inc.
Proximagen Neuroscience plc.
Newron Pharmaceuticals S.p.A.
DiaMedica Inc.
e-Therapeutics plc
Rexahn Pharmaceuticals, Inc.
Mithridion, Inc.
Teikoku Pharma USA, Inc.
Xel Pharmaceuticals, Inc.
Digna Biotech, S.L.
Oryzon
Eusa Pharma (Europe) Ltd.
TauRx Therapeutics Ltd
Ceregene, Inc.
Synosia Therapeutics AG
CoMentis, Inc.
AC Immune SA
Debiopharm Group
Humanetics Corporation
AFFiRiS AG
Noscira, S.A.
Accera, Inc.
Sonexa Therapeutics, Inc.
Immune Network Research Ltd.
Bio-Link
D-Pharm Ltd.
TauTaTis, Inc.
StemCells, Inc.
Probiodrug AG
Snowdon Inc.
Domain Therapeutics
Abiogen Pharma S.p.A.
Wellstat Therapeutics Corporation
BIOALVO S.A.
IMMD Inc.
Hawthorn Pharmaceuticals, Inc.
Neurimmune Therapeutics AG
BioArctic Neuroscience AB
Rottapharm SpA
Affichem
AmKor Pharma, Inc.
QR Pharma, Inc.
NeuroNascent, Inc.
Siena Biotech S.p.A.
SeneXta Therapeutics SA
Intellect Neurosciences, Inc.
Transtech Pharma, Inc.
Adeona Pharmaceuticals, Inc.
Intra-Cellular Therapies, Inc.
Targacept, Inc.
RemeGenix, Inc.
AB Science
Krenitsky Pharmaceuticals Inc.
Lipopharma
Link Medicine Corporation
PALUMED S.A.
M's Science Corporation
NasVax Ltd.
Stelic Institute & Co.
Dainippon Pharmaceutical Co., Ltd.
ArmaGen Technologies, Inc.
Archer Pharmaceuticals, Inc.
Varinel, Inc.
Cognosci, Inc.
RaQualia Pharma Inc.
Naurex, Inc.
PharmaNeuroBoost N.V.
Ampio Pharmaceuticals, Inc.
Universities/Institutes Involved in Alzheimer's Disease Therapeutics Development
Alzheimer's Disease - Therapeutics Assessment
Assessment by Monotherapy Products
Assessment by Combination Products
Assessment by Route of Administration
Assessment by Molecule Type
Late Stage Drug Profiles - Companies
AC-1204 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Bapineuzumab - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Dimebon - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Galantamine - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Lecozotan - Drug Profile
Product Description
Mechanism of Action
R&D Progress
LMTX - Drug Profile
Product Description
Mechanism of Action
R&D Progress
LY2062430 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Memryte - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Rivastach - Drug Profile
Product Description
Mechanism of Action
R&D Progress
SUN Y7017 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Late Stage Drug Profiles - Universities/Institutes
Alpha-Tocopherol + Namenda - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Doxycycline - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Doxycycline + Rifampicin - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Estradiol + Medroxyprogesterone - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Exelon Patch - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Ginkgo Biloba - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Memantine - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Modafinil - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Raloxifene - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Rifampin - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Rivastigmine - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Simvastatin - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Sunphenon EGCg - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Thalidomide - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Valproate - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Valproate - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Vitamin E + Selenium - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Discontinued Products
Alzheimer's Disease - Featured News
1. Dec 27, 2010: Intellect Obtains Pharmacokinetic Profile Report From 14 Day Safety Trial For OX1
2. Dec 21, 2010: Anavex Files Phase I Regulatory Submission For ANAVEX 2-73 In Alzheimer’s Disease
3. Dec 15, 2010: TauRx Wins European Patent For LMTX For Treatment Of Neurodegenerative Diseases
4. Dec 09, 2010: Neurokine Completes Phase II Clinical Trial Plan For NK-001 For Treatment Of Alzheimer's Type Memory Loss In CABG Patients
5. Dec 02, 2010: QR Pharma Receives FDA Clearance To Conduct Clinical Trials With Alzheimer Drug
6. Dec 02, 2010: QR Pharma Receives FDA Clearance To Conduct Clinical Trials With Bisnorcymserine In Treatment Of Alzheimer's Disease
7. Nov 08, 2010: Prana Biotechnology Plans To Advance Alzheimer's Clinical Trial With PBT2
8. Nov 05, 2010: Envivo Research Shows EVP-6124 Acts As Acetylcholine Co-Agonist
9. Oct 27, 2010: Intellect Obtains Phase Ib Draft Report Of OXIGON For Treatment Of Alzheimer's Disease
10. Oct 06, 2010: Adeona Completes 100% Enrollment In Pivotal Alzheimer’s Disease And Mild Cognitive Impairment Clinical Study
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Number of Products Under Development for Alzheimer's Disease, 2011
Products under Development for Alzheimer's Disease - Comparative Analysis, 2011
Comparative Analysis by Late Stage Development, 2011
Comparative Analysis by Mid Clinical Stage Development, 2011
Comparative Analysis by Early Clinical Stage Development, 2011
Comparative Analysis by Discovery and Pre-Clinical Stage Development, 2011
Bristol-Myers Squibb Company, 2011
DURECT Corporation, 2011
Johnson & Johnson, 2011
Boehringer Ingelheim GmbH, 2011
F. Hoffmann-La Roche Ltd., 2011
Abbott Laboratories, 2011
NsGene A/S, 2011
Sanofi-Aventis, 2011
AstraZeneca PLC, 2011
Eli Lilly and Company, 2011
GlaxoSmithKline plc, 2011
Antigenics, Inc., 2011
Daiichi Sankyo Company, Ltd, 2011
Merck & Co., Inc., 2011
United Biomedical, Inc., 2011
Dainippon Sumitomo Pharma Co., Ltd., 2011
Applied NeuroSolutions, Inc., 2011
Myriad Genetics, Inc., 2011
Takeda Pharmaceutical Company Limited, 2011
ExonHit Therapeutics SA, 2011
Plexxikon Inc., 2011
Mochida Pharmaceutical Co., Ltd., 2011
Avineuro Pharmaceuticals, Inc., 2011
Nanotherapeutics, Inc., 2011
Senexis Limited, 2011
Novartis AG, 2011
Samyang Corporation, 2011
EnVivo Pharmaceuticals, 2011
DECODON GmbH, 2011
Astellas Pharma Inc., 2011
Chiesi Farmaceutici SpA, 2011
Daewoong Pharmaceutical Co., Ltd., 2011
Eisai Co., Ltd., 2011
Elan Corporation, plc, 2011
H Lundbeck A/S, 2011
Octapharma AG, 2011
Ono Pharmaceutical Co., Ltd., 2011
Orion Corporation, 2011
Pfizer Inc., 2011
Sunesis Pharmaceuticals, Inc., 2011
Teva Pharmaceutical Industries Limited, 2011
Toyama Chemical Co. Ltd, 2011
Sandoz Inc., 2011
ENKAM Pharmaceuticals A/S, 2011
Astex Therapeutics Limited, 2011
Addex Pharmaceuticals, 2011
Evotec Aktiengesellschaft, 2011
Anavex Life Sciences Corp., 2011
Amicus Therapeutics, Inc., 2011
Idera Pharmaceuticals, Inc., 2011
Ligand Pharmaceuticals Incorporated, 2011
BELLUS Health Inc, 2011
Medivir AB, 2011
ReGenX Biosciences, LLC, 2011
Neuren Pharmaceuticals Limited, 2011
Neuro-Hitech, Inc., 2011
Cortex Pharmaceuticals, Inc., 2011
Critical Outcome Technologies Inc., 2011
ACADIA Pharmaceuticals Inc., 2011
Medivation, Inc., 2011
ProteoTech, Inc., 2011
Theratechnologies Inc., 2011
Phytopharm Plc, 2011
SYGNIS Pharma AG, 2011
Prana Biotechnology Limited, 2011
Hanall Pharmaceutical Co., Ltd., 2011
SCOLR Pharma, Inc., 2011
Transition Therapeutics Inc., 2011
Allon Therapeutics Inc., 2011
Neurim Pharmaceuticals (1991) Ltd., 2011
Samaritan Pharmaceuticals, Inc., 2011
Theravance, Inc., 2011
Resverlogix Corp., 2011
Suven Life Sciences Ltd., 2011
Galapagos NV, 2011
MediPost Co., Ltd., 2011
Sucampo Pharmaceuticals, Inc., 2011
Proximagen Neuroscience plc., 2011
Newron Pharmaceuticals S.p.A., 2011
DiaMedica Inc., 2011
e-Therapeutics plc, 2011
Rexahn Pharmaceuticals, Inc., 2011
Mithridion, Inc., 2011
Teikoku Pharma USA, Inc., 2011
Xel Pharmaceuticals, Inc., 2011
Digna Biotech, S.L., 2011
Oryzon, 2011
Eusa Pharma (Europe) Ltd., 2011
TauRx Therapeutics Ltd, 2011
Ceregene, Inc., 2011
Synosia Therapeutics AG, 2011
CoMentis, Inc., 2011
AC Immune SA, 2011
Debiopharm Group, 2011
Humanetics Corporation, 2011
AFFiRiS AG, 2011
Noscira, S.A., 2011
Accera, Inc., 2011
Sonexa Therapeutics, Inc., 2011
Immune Network Research Ltd., 2011
Bio-Link, 2011
D-Pharm Ltd., 2011
TauTaTis, Inc., 2011
StemCells, Inc., 2011
Probiodrug AG, 2011
Snowdon Inc., 2011
Domain Therapeutics, 2011
Abiogen Pharma S.p.A., 2011
Wellstat Therapeutics Corporation, 2011
BIOALVO S.A., 2011
IMMD Inc., 2011
Hawthorn Pharmaceuticals, Inc., 2011
Neurimmune Therapeutics AG, 2011
BioArctic Neuroscience AB, 2011
Rottapharm SpA, 2011
Affichem, 2011
AmKor Pharma, Inc., 2011
QR Pharma, Inc., 2011
NeuroNascent, Inc., 2011
Siena Biotech S.p.A., 2011
SeneXta Therapeutics SA, 2011
Intellect Neurosciences, Inc., 2011
Transtech Pharma, Inc., 2011
Adeona Pharmaceuticals, Inc., 2011
Intra-Cellular Therapies, Inc., 2011
Targacept, Inc., 2011
RemeGenix, Inc., 2011
AB Science, 2011
Krenitsky Pharmaceuticals Inc., 2011
Lipopharma, 2011
Link Medicine Corporation, 2011
PALUMED S.A., 2011
M's Science Corporation, 2011
NasVax Ltd., 2011
Stelic Institute & Co., 2011
Dainippon Pharmaceutical Co., Ltd., 2011
ArmaGen Technologies, Inc., 2011
Archer Pharmaceuticals, Inc., 2011
Varinel, Inc., 2011
Cognosci, Inc., 2011
RaQualia Pharma Inc., 2011
Naurex, Inc., 2011
PharmaNeuroBoost N.V., 2011
Ampio Pharmaceuticals, Inc., 2011
Assessment by Monotherapy Products, 2011
Assessment by Combination Products
Assessment by Stage and Route of Administration, 2011
Assessment by Molecule Type, 2011
Discontinued Products
List of Figures
Number of Products under Development for Alzheimer's Disease, 2011
Products under Development for Alzheimer's Disease - Comparative Analysis, 2011
Products under Development by Companies, 2011
Products under Investigation by Universities/Institutes, 2011
Late Stage Products, 2011
Mid Clinical Stage Products, 2011
Early Clinical Stage Products, 2011
Discovery and Pre-Clinical Stage Products, 2011
Assessment by Monotherapy Products, 2011
Assessment by Combination Products, 2011
Assessment by Route of Administration, 2011
Assessment by Stage and Route of Administration, 2011
Assessment by Molecule Type, 2011
Assessment by Stage and Molecule Type, 2011

Abstract

Alzheimer's Disease - Pipeline Review, Q1 2011

Summary

Global Markets Direct’s, 'Alzheimer's Disease - Pipeline Review, Q1 2011', provides an overview of the Alzheimer's Disease therapeutic pipeline. This report provides information on the therapeutic development for Alzheimer's Disease, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Alzheimer's Disease. 'Alzheimer's Disease - Pipeline Review, Q1 2011' is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope
  • A snapshot of the global therapeutic scenario for Alzheimer's Disease.
  • A review of the Alzheimer's Disease products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • Coverage of products based on various stages of development ranging from discovery till registration stages.
  • A feature on pipeline projects on the basis of monotherapy and combined therapeutics.
  • Coverage of the Alzheimer's Disease pipeline on the basis of therapeutic class, route of administration and molecule type.
  • Profiles of late-stage pipeline products featuring sections on product description, mechanism of action and research & development progress.
  • Key discontinued pipeline projects.
  • Latest news and deals relating to the products.
Reasons to buy
  • Identify and understand important and diverse types of therapeutics under development for Alzheimer's Disease.
  • Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive advantage.
  • Plan mergers and acquisitions effectively by identifying players with the most promising pipeline.
  • Devise corrective measures for pipeline projects by understanding Alzheimer's Disease pipeline depth and focus of Alzheimer's Disease therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline.


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