Alzheimer's Disease - Pipeline Review, Q4 2010

Published by: Global Markets Direct

Published: Dec. 8, 2010 - 148 Pages


Table of Contents

Introduction
Global Markets Direct Report Coverage
Alzheimer's Disease Overview
An Overview of Pipeline Products for Alzheimer's Disease
Alzheimer's Disease Therapeutics under Development by Companies
Alzheimer's Disease Therapeutics under Investigation by Universities/Institutes
Late Stage Products
Comparative Analysis
Mid Clinical Stage Products
Comparative Analysis
Early Clinical Stage Products
Comparative Analysis
Discovery and Pre-Clinical Stage Products
Comparative Analysis
Companies Involved in Alzheimer's Disease Therapeutics Development
Bristol-Myers Squibb Company
DURECT Corporation
Johnson & Johnson
Boehringer Ingelheim GmbH
Abbott Laboratories
NsGene A/S
Sanofi-Aventis
AstraZeneca PLC
Eli Lilly and Company
GlaxoSmithKline plc
Antigenics, Inc.
Daiichi Sankyo Company, Ltd
Merck & Co., Inc.
United Biomedical, Inc.
Dainippon Sumitomo Pharma Co., Ltd.
Myriad Genetics, Inc.
Takeda Pharmaceutical Company Limited
ExonHit Therapeutics SA
Plexxikon Inc.
Mochida Pharmaceutical Co., Ltd.
Avineuro Pharmaceuticals, Inc.
Senexis Limited
Novartis AG
EnVivo Pharmaceuticals
DECODON GmbH
Astellas Pharma Inc.
Cephalon, Inc.
Chiesi Farmaceutici SpA
Daewoong Pharmaceutical Co., Ltd.
Elan Corporation, plc
H Lundbeck A/S
Octapharma AG
Orion Corporation
Pfizer Inc.
Sunesis Pharmaceuticals, Inc.
Teva Pharmaceutical Industries Limited
Toyama Chemical Co. Ltd
ENKAM Pharmaceuticals A/S
Astex Therapeutics Limited
Addex Pharmaceuticals
Evotec Aktiengesellschaft
Anavex Life Sciences Corp.
Amicus Therapeutics, Inc.
Genfit
Idera Pharmaceuticals, Inc.
Ligand Pharmaceuticals Incorporated
BELLUS Health Inc
Medivir AB
ReGenX Biosciences, LLC
Neuren Pharmaceuticals Limited
Neuro-Hitech, Inc.
Cortex Pharmaceuticals, Inc.
Critical Outcome Technologies Inc.
ACADIA Pharmaceuticals Inc.
Medivation, Inc.
Keryx Biopharmaceuticals, Inc.
EPIX Pharmaceuticals, Inc.
ProteoTech, Inc.
Theratechnologies Inc.
Phytopharm Plc
SYGNIS Pharma AG
Prana Biotechnology Limited
Hanall Pharmaceutical Co., Ltd.
SCOLR Pharma, Inc.
Transition Therapeutics Inc.
Neurim Pharmaceuticals (1991) Ltd.
Samaritan Pharmaceuticals, Inc.
Theravance, Inc.
Suven Life Sciences Ltd.
Galapagos NV
MediPost Co., Ltd.
Sucampo Pharmaceuticals, Inc.
Proximagen Neuroscience plc.
Newron Pharmaceuticals S.p.A.
DiaMedica Inc.
e-Therapeutics plc
Mithridion, Inc.
Teikoku Pharma USA, Inc.
Xel Pharmaceuticals, Inc.
Eisai Inc.
Digna Biotech, S.L.
Eusa Pharma (Europe) Ltd.
TauRx Therapeutics Ltd
Ceregene, Inc.
Synosia Therapeutics AG
CoMentis, Inc.
AC Immune SA
Debiopharm Group
Humanetics Corporation
Noscira, S.A.
Sonexa Therapeutics, Inc.
Immune Network Research Ltd.
Bio-Link
D-Pharm Ltd.
TauTaTis, Inc.
Probiodrug AG
Snowdon Inc.
Domain Therapeutics
Abiogen Pharma S.p.A.
Wellstat Therapeutics Corporation
BIOALVO S.A.
IMMD Inc.
Hawthorn Pharmaceuticals, Inc.
Neurimmune Therapeutics AG
BioArctic Neuroscience AB
Rottapharm SpA
AmKor Pharma, Inc.
QR Pharma, Inc.
NeuroNascent, Inc.
SeneXta Therapeutics SA
Intellect Neurosciences, Inc.
Transtech Pharma, Inc.
Adeona Pharmaceuticals, Inc.
Intra-Cellular Therapies, Inc.
RemeGenix, Inc.
AB Science
Krenitsky Pharmaceuticals Inc.
Lipopharma
Medisyn Technologies, Inc.
M's Science Corporation
BrainCells Inc.
Dainippon Pharmaceutical Co., Ltd.
Varinel, Inc.
RaQualia Pharma Inc.
Naurex, Inc.
Ampio Pharmaceuticals, Inc.
Universities/Institutes Involved in Alzheimer's Disease Therapeutics Development
Alzheimer's Disease Therapeutics Assessment
Assessment by Monotherapy Products
Assessment by Combination Products
Assessment by Route of Administration
Assessment by Molecule Type
Late Stage Drug Profiles - Companies
Alzhemed - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Bapineuzumab - Drug Profile
Product Description
Mechanism of Action
R&D Progress
BCI-224 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Dimebon - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Lecozotan - Drug Profile
Product Description
Mechanism of Action
R&D Progress
LY2062430 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Memryte - Drug Profile
Product Description
Mechanism of Action
R&D Progress
QS-21 Stimulon Adjuvant - Drug Profile
Product Description
Mechanism of Action
R&D Progress
R113675 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
SUN Y7017 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Late Stage Drug Profiles - Universities/Institutes
Alpha-Tocopherol + Namenda - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Doxycycline - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Doxycycline + Rifampicin - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Estradiol + Medroxyprogesterone - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Ginkgo Biloba - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Memantine - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Raloxifene - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Rifampin - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Simvastatin - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Sunphenon EGCg - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Thalidomide - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Valproate - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Valproate - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Vitamin E + Selenium - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Discontinued Products
Alzheimer's Disease - Featured News
Dec 02, 2010: QR Pharma Receives FDA Clearance To Conduct Clinical Trials With Alzheimer Drug
Dec 02, 2010: QR Pharma Receives FDA Clearance To Conduct Clinical Trials With Bisnorcymserine In Treatment Of Alzheimer's Disease
Nov 08, 2010: Prana Biotechnology Plans To Advance Alzheimer's Clinical Trial With PBT2
Nov 05, 2010: Envivo Research Shows EVP-6124 Acts As Acetylcholine Co-Agonist
Oct 27, 2010: Intellect Obtains Phase Ib Draft Report Of OXIGON For Treatment Of Alzheimer's Disease
Oct 06, 2010: Adeona Completes 100% Enrollment In Pivotal Alzheimer’s Disease And Mild Cognitive Impairment Clinical Study
Sep 24, 2010: Update Of Product Withdrawal/Product Recall Octopharm's Octagam 10% (octagam 100mg/ml)
Sep 13, 2010: Anave Announces Publication Of Data On Anavex 2-73 For Alzheimer’s Disease In Journal of Psychopharmacology
Sep 02, 2010: Addex's mGluR2 Shows Efficacy In Alzheimer’s Disease Model
Aug 19, 2010: Curaxis Provides Update On Memryte For Treatment Of Alzheimer's Disease
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Number of Products Under Development for Alzheimer's Disease, 2010
Products under Development for Alzheimer's Disease - Comparative Analysis, 2010
Comparative Analysis by Late Stage Development, 2010
Comparative Analysis by Mid Clinical Stage Development, 2010
Comparative Analysis by Early Clinical Stage Development, 2010
Comparative Analysis by Discovery and Pre-Clinical Stage Development, 2010
Bristol-Myers Squibb Company, 2010
DURECT Corporation, 2010
Johnson & Johnson, 2010
Boehringer Ingelheim GmbH, 2010
Abbott Laboratories, 2010
NsGene A/S, 2010
Sanofi-Aventis, 2010
AstraZeneca PLC, 2010
Eli Lilly and Company, 2010
GlaxoSmithKline plc, 2010
Antigenics, Inc., 2010
Daiichi Sankyo Company, Ltd, 2010
Merck & Co., Inc., 2010
United Biomedical, Inc., 2010
Dainippon Sumitomo Pharma Co., Ltd., 2010
Myriad Genetics, Inc., 2010
Takeda Pharmaceutical Company Limited, 2010
ExonHit Therapeutics SA, 2010
Plexxikon Inc., 2010
Mochida Pharmaceutical Co., Ltd., 2010
Avineuro Pharmaceuticals, Inc., 2010
Senexis Limited, 2010
Novartis AG, 2010
EnVivo Pharmaceuticals, 2010
DECODON GmbH, 2010
Astellas Pharma Inc., 2010
Cephalon, Inc., 2010
Chiesi Farmaceutici SpA, 2010
Daewoong Pharmaceutical Co., Ltd., 2010
Elan Corporation, plc, 2010
H Lundbeck A/S, 2010
Octapharma AG, 2010
Orion Corporation, 2010
Pfizer Inc., 2010
Sunesis Pharmaceuticals, Inc., 2010
Teva Pharmaceutical Industries Limited, 2010
Toyama Chemical Co. Ltd, 2010
ENKAM Pharmaceuticals A/S, 2010
Astex Therapeutics Limited, 2010
Addex Pharmaceuticals, 2010
Evotec Aktiengesellschaft, 2010
Anavex Life Sciences Corp., 2010
Amicus Therapeutics, Inc., 2010
Genfit, 2010
Idera Pharmaceuticals, Inc., 2010
Ligand Pharmaceuticals Incorporated, 2010
BELLUS Health Inc, 2010
Medivir AB, 2010
ReGenX Biosciences, LLC, 2010
Neuren Pharmaceuticals Limited, 2010
Neuro-Hitech, Inc., 2010
Cortex Pharmaceuticals, Inc., 2010
Critical Outcome Technologies Inc., 2010
ACADIA Pharmaceuticals Inc., 2010
Medivation, Inc., 2010
Keryx Biopharmaceuticals, Inc., 2010
EPIX Pharmaceuticals, Inc., 2010
ProteoTech, Inc., 2010
Theratechnologies Inc., 2010
Phytopharm Plc, 2010
SYGNIS Pharma AG, 2010
Prana Biotechnology Limited, 2010
Hanall Pharmaceutical Co., Ltd., 2010
SCOLR Pharma, Inc., 2010
Transition Therapeutics Inc., 2010
Neurim Pharmaceuticals (1991) Ltd., 2010
Samaritan Pharmaceuticals, Inc., 2010
Theravance, Inc., 2010
Suven Life Sciences Ltd., 2010
Galapagos NV, 2010
MediPost Co., Ltd., 2010
Sucampo Pharmaceuticals, Inc., 2010
Proximagen Neuroscience plc., 2010
Newron Pharmaceuticals S.p.A., 2010
DiaMedica Inc., 2010
e-Therapeutics plc, 2010
Mithridion, Inc., 2010
Teikoku Pharma USA, Inc., 2010
Xel Pharmaceuticals, Inc., 2010
Eisai Inc., 2010
Digna Biotech, S.L., 2010
Eusa Pharma (Europe) Ltd., 2010
TauRx Therapeutics Ltd, 2010
Ceregene, Inc., 2010
Synosia Therapeutics AG, 2010
CoMentis, Inc., 2010
AC Immune SA, 2010
Debiopharm Group, 2010
Humanetics Corporation, 2010
Noscira, S.A., 2010
Sonexa Therapeutics, Inc., 2010
Immune Network Research Ltd., 2010
Bio-Link, 2010
D-Pharm Ltd., 2010
TauTaTis, Inc., 2010
Probiodrug AG, 2010
Snowdon Inc., 2010
Domain Therapeutics, 2010
Abiogen Pharma S.p.A., 2010
Wellstat Therapeutics Corporation, 2010
BIOALVO S.A., 2010
IMMD Inc., 2010
Hawthorn Pharmaceuticals, Inc., 2010
Neurimmune Therapeutics AG, 2010
BioArctic Neuroscience AB, 2010
Rottapharm SpA, 2010
AmKor Pharma, Inc., 2010
QR Pharma, Inc., 2010
NeuroNascent, Inc., 2010
SeneXta Therapeutics SA, 2010
Intellect Neurosciences, Inc., 2010
Transtech Pharma, Inc., 2010
Adeona Pharmaceuticals, Inc., 2010
Intra-Cellular Therapies, Inc., 2010
RemeGenix, Inc., 2010
AB Science, 2010
Krenitsky Pharmaceuticals Inc., 2010
Lipopharma, 2010
Medisyn Technologies, Inc., 2010
M's Science Corporation, 2010
BrainCells Inc., 2010
Dainippon Pharmaceutical Co., Ltd., 2010
Varinel, Inc., 2010
RaQualia Pharma Inc., 2010
Naurex, Inc., 2010
Ampio Pharmaceuticals, Inc., 2010
Assessment by Monotherapy Products, 2010
Assessment by Combination Products
Assessment by Stage and Route of Administration, 2010
Assessment by Molecule Type, 2010
Discontinued Products
List of Figures
Number of Products under Development for Alzheimer's Disease, 2010
Products under Development for Alzheimer's Disease - Comparative Analysis, 2010
Products under Development by Companies, 2010
Products under Investigation by Universities/Institutes, 2010
Late Stage Products, 2010
Mid Clinical Stage Products, 2010
Early Clinical Stage Products, 2010
Discovery and Pre-Clinical Stage Products, 2010
Assessment by Monotherapy Products, 2010
Assessment by Combination Products, 2010
Assessment by Route of Administration, 2010
Assessment by Stage and Route of Administration, 2010
Assessment by Molecule Type, 2010
Assessment by Stage and Molecule Type, 2010

Abstract

Alzheimer's Disease - Pipeline Review, Q4 2010

Summary

Global Markets Direct’s, “Alzheimer's Disease Pipeline Review, Q4 2010”, provides an overview of the Alzheimer's Disease therapeutic pipeline. This report provides information on the therapeutic development for Alzheimer's Disease, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Alzheimer's Disease. “Alzheimer's Disease-Pipeline Review 2010, Q4 2010” is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team.

Scope
  • A snapshot of the global therapeutic scenario for Alzheimer's Disease.
  • A review of the Alzheimer's Disease products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • Coverage of products based on various stages of development ranging from discovery till registration stages.
  • A feature on pipeline projects on the basis of monotherapy and combined therapeutics.
  • Coverage of the Alzheimer's Disease pipeline on the basis of therapeutic class, route of administration and molecule type.
  • Profiles of late-stage pipeline products featuring sections on product description, mechanism of action and research & development progress.
  • Key discontinued pipeline projects.
  • Latest news and deals relating to the products.
Reasons to buy
  • Identify and understand important and diverse types of therapeutics under development for Alzheimer's Disease.
  • Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive advantage.
  • Plan mergers and acquisitions effectively by identifying players with the most promising pipeline.
  • Devise corrective measures for pipeline projects by understanding Alzheimer's Disease pipeline depth and focus of Alzheimer's Disease therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline.


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