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Medical Imaging Markets: Contrast Agents

The application and versatility of medical imaging modalities are continuing to grow in significance as the population ages and healthcare costs rise. Examinations that can facilitate earlier disease diagnosis and the most appropriate treatment are in order. This bodes well for contrast media markets.

Since our last round-up of the contrast media market, the economic environment in the world has changed. Although the recession may have caused hospitals, physician offices and other institutions to delay or cancel the purchase of imaging equipment, it has not had a significant negative impact on the use of contrast agents with the equipment already on hand. Specifically, annual growth for medical contrast media during the next five years appears to be strong, despite the recession slowing capital equipment purchases. Imaging exams are still needed for many diagnoses, and contrast enhancement facilitates diagnosis in many cases. Kalorama expects growth ranges to remain high.

This comprehensive study of the world market for contrast agents builds on the previous modality-focused reports of Kalorama's medical imaging market reports. Coverage includes:

  • World and regional revenue forecasts for contrast agents and radiopharmaceuticals by modality through 2012. (X-Ray, CT, Ultrasound, MRI, PET, SPECT)
  • Market share of the major contrast agent supplers
  • Procedure volumes by modality and region
  • Estimates of the portion of procedures in each modality using contrast enhancement
  • Contrast-enhancement products in development

The report also discusses technical developments and emerging application trends such as therapeutic monitoring, whole body screening, and guided therapeutic interventions, and how contrast agents are helping to expand imaging’s role in basic research and drug discovery/development. Specific advances in contrast agent-enabled diagnostics for mammography, Alzheimer’s, and other indications are also reviewed.

The report concludes with profiles of top suppliers and developers including:

  • Acusphere Inc.
  • Alseres Pharmaceuticals Inc.
  • Amag Pharmaceuticals Inc.
  • Aposense Ltd.
  • Avid Radiopharmaceuticals Inc.
  • Bayer Schering Pharma
  • Bracco SpA
  • Cell Point
  • Covidien Ltd.
  • Daiichi Pharmaceutical Co. Ltd.
  • Dendritic NanoTechnologies Inc.
  • Draximage
  • Endocyte Inc.
  • Eusa Pharma
  • GE Healthcare
  • Guerbet Group
  • Hovione FarmaCiencia SA
  • Imcor Pharmaceutical Co.
  • Immunomedics Inc.
  • Insight Agents GmbH
  • King Pharmaceuticals Inc.
  • Luna nanoWorks
  • Macrocyclics
  • MDS Nordion
  • NanoScan Imaging
  • Palatin Technologies Inc.
  • Pharmacyclics
  • Point Biomedical Corp.
  • Starpharma Holdings Ltd.
  • VisEn Medical Inc.


New York, January 29, 2010 — Published reports on the usefulness of CT scans for complicated H1N1 cases has spurred use of these procedures in U.S. hospitals. According to healthcare market research publisher Kalorama Information, this opens up a pathway of diagnostics for physicians and overall is a positive sign not only for the technology but also for companies making chemical agents for procedures. In the recent report Medical Imaging Markets: Contrast Agents, Kalorama estimates the sale of CT contrast agents in the U.S. at $880 million in 2009.

Computed tomography (CT) uses energy waves to image the human body and renders an image in 3D from a series of two-dimensional x-rays. Although it is not completely novel for a CT scan to be ordered for flu cases where pain is reported, a new study suggests the technology is preferable to x-rays. The study, conducted in coordination with the University of Michigan Health Service and published in the December 2009 issue of the American Journal of Roentgenology, has given new support to the modality’s usage in the most severe cases of the H1N1 flu virus.

The study, which consisted of a review of thousands of patient records, offered several important findings: that H1N1 flu can cause pulmonary embolism, that PE may be responsible for H1N1 deaths, and that physician evaluation of patients diagnosed with respiratory complications via contrast-enhanced CT scan is recommended. The study did not establish the technology as a test for detecting the virus itself. The primary test for H1N1 is an immunoassay that can detect antigens for specific strains of flu. But the study supports using the CT scan as an adjunctive tool after other tests are performed, to determine if the patient’s flu is a major case.

“This is one of many areas where the agent-enhanced CT scan is playing a supporting role in diagnosis,” said Bruce Carlson, publisher of Kalorama Information. “Physicians are increasingly comfortable with computed tomography when a diagnosis is not clear from other modalities.”

Trauma, pediatric health, vascular imaging and cardiac imaging are among the areas where CT scans are employed, and other areas are being investigated. Kalorama estimates that over 54.5 million imaging procedures were performed in the U.S. in 2009, most requiring some kind of contrast agent. GE Healthcare, Covidien, Bayer, and Guerbet are among the large manufacturers of contrast agents used for computed tomography.

Kalorama Information’s Medical Imaging Markets: Contrast Agents analyzes the world market for contrast media used with medical imaging diagnostic systems and for radiopharmaceuticals used in molecular imaging. The report includes market estimates, forecasts and company profiles.

About Kalorama Information
Kalorama Information supplies the latest in independent market research in the life sciences, as well as a full range of custom research services.

  • Executive Summary
    • THE CONTRAST REVOLUTION
    • X-RAY AND CT
    • ULTRASOUND
    • MRI
    • RADIOPHARMACEUTICALS
    • WORLD MARKET SUMMARY
      • Market Drivers and Trends
      • Market Challenges
      • World Market Growth Analysis
        • Table World Market for X-Ray Medical Contrast Media , 2008-2012
        • Table World Market for CT Medical Contrast Media 2008-2012
        • Table World Market for Ultrasound Medical Contrast Media , 2008-2012
        • Table World Market for MRI Medical Contrast Media 2008-2012
        • Table World Market for PET Radiopharmaceuticals, 2008-2012
        • Table World Market for SPECT Radiopharmaceuticals , 2008-2012
    • METHODOLOGY
  • Introduction
    • HARNESSING SCIENCE TO OPTIMIZE OUTCOMES
    • HISTORY AND EVOLUTION
    • KEY MARKETS
      • Table Key Medical Contrast Agents by Type
      • X-Ray and CT
      • Ultrasound
      • MRI
      • Nuclear Medicine
    • IONIC AND NON-IONIC CONTRAST
      • Table Advantages of Non-Ionic Contrast Media
    • REIMBURSEMENT AND OTHER CONCERNS
      • Volume Determination
      • Safety
      • Combination Technology
  • Promising Developments
    • DETECTING PROSTATE CANCER
    • ASSESSING HEART RISK
    • BREAST CHEMO OUTCOME
    • SOFTWARE ENHANCEMENT
    • FOUR IN ONE
    • PHOTOACOUSTIC TOMOGRAPHY
    • CARBON DOTS
    • NANOMAGNETS
    • KIDNEY DAMAGE
    • ANGIOGRAPHY
    • Iodinated Contrast
    • Children
    • Dynamic Contrast-Enhanced MRI
    • Preclinical
    • Nanocolloids
  • Markets
    • MARKET DRIVERS
      • Table Patent Status of Selected Medical Imaging Agents
      • Table World Market for Medical Contrast Media and Radiopharmaceuticals, 2007-2012 2008 2010 2012
      • Targeted Imaging
      • Increasing Specificity
      • Aging Population
    • UTILIZATION
      • Procedures
        • Table World Market Geographic Segmentation for Medical X-Ray Procedures, 2008
        • Table Worldwide Medical MRI Procedures
        • Table Worldwide Medical CT Procedures
        • Table Worldwide Medical Ultrasound Procedures
        • Table Worldwide Medical PET Procedures, 2008
    • OUTLOOK FOR CONTRAST MEDIA
      • Table Status of Selected Medical Imaging Agents
      • Market Forecast
        • Table World Market for X-Ray Contrast Media 2007-2012
        • Table World Market for Medical X-Ray Contrast Media by Geographic Segment 2007-2012
        • Table World Market for Medical CT Contrast Media 2007-2012
        • Table World Market for Medical CT Contrast Media by Geographic Segment 2007-2012
        • Table World Market for Medical Ultrasound Contrast Media 2007-2012
        • Table World Market for Medical Ultrasound Contrast Media by Geographic Segment, 2007-2012
        • Table World Market for Medical MRI Contrast Media 2007-2012
        • Table World Market for Medical MRI Contrast Media by Geographic Segment, 2007-2012
    • OUTLOOK FOR MOLECULAR IMAGING AGENTS
      • Market Forecast
        • Table Selected Molecular Imaging Products
        • Table World Market for Medical PET Radiopharmaceuticals, 2007-2012
        • Table World Market for Medical PET Radiopharmaceuticals by Geographic Segment 2007-2012
        • Table World Market for Medical SPECT Radiopharmaceuticals 2007-2012
        • Table World Market for Medical SPECT Radiopharmaceuticals by Geographic Segment 2007-2012
  • Corporate Profiles
    • ACUSPHERE INC.
    • ALSERES PHARMACEUTICALS INC.
    • AMAG PHARMACEUTICALS INC.
    • APOSENSE LTD.
    • ART ADVANCED RESEARCH TECHNOLOGIES INC.
    • AVID RADIOPHARMACEUTICALS INC.
    • BAYER SCHERING PHARMA
    • BIOSCAN INC.
    • BRACCO SPA
    • CELL>POINT
    • COVIDIEN LTD.
    • DAIICHI PHARMACEUTICAL CO. LTD.
    • DENDRITIC NANOTECHNOLOGIES INC.
    • DRAXIMAGE
    • ENDOCYTE INC.
    • EUSA PHARMA
    • FLUOROPHARMA INC.
    • GE HEALTHCARE
    • GUERBET GROUP
    • HOVIONE FARMACIENCIA SA
    • IMCOR PHARMACEUTICAL CO.
    • IMMUNOMEDICS INC.
    • INSIGHT AGENTS GMBH
    • KING PHARMACEUTICALS INC.
    • LANTHEUS MEDICAL IMAGING
    • LUNA NANOWORKS
    • MACROCYCLICS
    • MDS NORDION
    • MOLECULAR INSIGHT PHARMACEUTICALS INC.
    • NANOSCAN IMAGING
    • PALATIN TECHNOLOGIES INC.
    • PHARMACYCLICS
    • PHOTODETECTION SYSTEMS INC.
    • POINT BIOMEDICAL CORP.
    • STARPHARMA HOLDINGS LTD.
    • VISEN MEDICAL INC.

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