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Liquid Chromatography Markets (LC, HPLC and UHPLC)


Attention: There is an updated edition available for this report.

The liquid chromatography (LC) market has been relatively mature for quite a while, with a slow evolution of products and applications over the last few decades. High performance liquid chromatography (HPLC) has used essentially the same types of components since the 1980s. However, the market has seen an extraordinary amount of technological change in the last few years as companies have continued to introduce new systems performing fast LC and ultra HPLC (UHPLC).

This report, Liquid Chromatography Markets,, represents Kalorama's most comprehensive look at this dynamic market. This report covers liquid chromatography systems, hardware, software, consumables, and related services, with a focus on HPLC. Both analytical and purification applications are included, but the emphasis leans towards analytical techniques. With quantitative data, a discussion of trends, and expert analysis, the report is perfect for those seeking and understanding of the LC industyr. Included the report is the following:

  • Market Forecasts
  • Overview of the LC Market
  • Product Offerings by Company
  • Breadown of LC Market by Region (US, Europe, Asia, ROW)
  • Detail of Trends and How They Will Impact Market
  • List of Major LC-related Deals since 2003.
  • Company Profiles
  • Details from the HPLC 2008 Convention
  • Seven key Strategic Recommendations for Success in this Market
  • Discussion of the Role of Liquid Chromatography in Food Testing
The research for this report combined a variety of primary and secondary sources. Primary sources included end-users, LC suppliers’ personnel, and other pertinent individuals. Secondary sources included suppliers’ financial statements, websites, journals, trade publications, and other periodicals.

Companies profiled in this report include the following:

  • Agilent Technologies
  • Bio-Rad
  • Dionex
  • Eksigent Technologies
  • ESA Biosciences
  • GE Healthcare
  • Grace Davison Discovery Sciences (W.R. Grace & Co.)
  • Hitachi High Technologies
  • Proxeon Biosystems
  • Shimadzu
  • Thermo Fisher Scientific
  • Varian
  • Waters Corp.


  • Executive Summary
    • APPLICATIONS AND INDUSTRIES
    • SCOPE AND METHODOLOGY
  • Introduction
    • BACKGROUND AND DEFINITIONS
      • Pumps
      • Columns
      • Detectors
      • Other Accessories and Consumables
    • APPLICATIONS AND INDUSTRIES
    • SCOPE AND METHODOLOGY
  • Market Trends
    • COLLABORATIONS, M&A ACTIVITY, REGIONAL EXPANSION
    • RISE OF DIAGNOSTICS AND OTHER CLINICAL APPLICATIONS
      • HPLC Spreading Into Niches in Clinical Labs
      • Advantages and Disadvantages of LC-MS in Clinical Applications
      • Detection of Doping Agents Using LC-MS
      • Therapeutic Drug Monitoring of Fentanyl in Urine With LC-MS-MS
      • Forensic Toxicology Using LC-MS-MS
      • Discovery and Detection of Genetic Variation by DHPLC
      • Measuring the Level of Vitamin D in Blood
    • INCREASED GLOBAL FOCUS ON FOOD SAFETY
      • Introduction
      • European Union Updates Maximum Residue Levels for Pesticides
      • Japan Establishes Positive List System
      • Melamine Contamination of Pet Foods and Dairy
      • FDA Publishes Laboratory Information Bulletin on Melamine, May 2007
      • FDA Publishes Laboratory Information Bulletin on Melamine, October 2008
      • Agilent Technologies Addresses Melamine in Food
    • GREEN, ECO-FRIENDLY TRENDS AFFECTING LC MARKET
      • Table Factors Driving Green Initiatives at Labs (Factor, Percent of Respondents)
      • Production Scale LC and Process Analytical LC Gaining Momentum
      • LC, GC, SFC Applications Blurring
      • Microfluidics and Other Chips Gradually Gaining Ground
      • Chiral Separations Gaining Importance
      • FDA Issues Policy Statements on Chiral Drugs
      • LC Products for Chiral Separations Proliferate
      • Hydrophilic Interaction Chromatography (HILIC) Experiencing Rapid Growth
      • Nano-LC and Nano-electrospray Find Strong Niche Markets
        • Table Nano-LC Systems, 2008
      • Protein Analysis, Proteomics Driving Market
    • UHPLC AND FAST LC TECHNOLOGIES
      • Shaking Up a Mature Market
      • Decreasing Particle Size and the van Deemter Curve
      • UHPLC and Fast LC Product Introductions Stimulate Market
        • Table UHPLC and Fast LC Systems along with Type of Technology and Pressure Limits
        • Table Columns with 2.0 and sub-2 um totally porous particles, 2008
      • Advances Create Market for New Parts, Consumables, Ancillary Products
    • ALTERNATIVE OR INTERMEDIATE FORMS OF FAST, FASTER LC
      • Using Standard Pressures for Fast LC
      • High Temperature LC
        • Table Columns Designed for High Temperature LC (HTLC)
      • Particle Sizes of 2 um to 3 µm
        • Table Columns with 2 to 3 um totally porous particles, 2008
      • Superficially Porous Particles
      • Optimizing Extra-Column Volume, Other Paramaters
        • Table Papers presented at HPLC 2007 and HPLC 2008 (percent)
        • Table Particle Size usage, 1997 & 2007 (percent)
        • Table Stationary Phase Used, 2008 (percent)
        • Table Stationary Phase Used in RP-HPLC, 2007 (percent)
        • Table Analytical HPLC Mode and Stationary Phase Usage, 2007 (percent)
        • Table Papers Presented at HPLC 2008 (percent)
        • Table Number of Sample Injections During Column Life (percent)
        • Table Average Analytical Column Lifetime (percent)
        • Table Sources for HPLC Columns Purchase (percent)
        • Table Factors Driving Green Initiatives at Labs (percent)
        • Table Column Developments of Interest in the Future (percent)
        • Table Anticipated Usage & Impact of UPLC/UHPLC in Next 5-8 Years, 2008 (percent)
  • Products
    • ADVANCED MATERIALS TECHNOLOGY, INC.
      • Halo HPLC Columns
    • AGILENT TECHNOLOGIES
      • 1200 Series Rapid Resolution LC (RRLC)
      • HPLC-Chips
    • BIO-RAD
      • BioLogic DuoFlow
    • EKSIGENT TECHNOLOGIES
      • expressHT-Ultra
    • ESA BIOSCIENCES
      • Corona Charged Aerosol Detector (CAD)
      • Coulochem and CoulArray Detectors
    • HITACHI HIGH TECHNOLOGIES
      • LaChromUltra
    • THERMO FISHER SCIENTIFIC
      • TurboFlow Columns
    • VARIAN
      • 920-LC
    • WATERS
      • Acquity UPLC
  • Deals
    • Table Deals (Company 1, Company 2, Date, Comments)
  • Revenues Forecast and Competitive Analysis
    • Table World LC Market, 2007-2013 ($M and percent)
    • Table Regional Distribution, World Liquid Chromatography Market
    • ASSUMPTIONS
    • COMPETITIVE ANALYSIS
      • Table Revenues of LC Suppliers ($)
      • Table Market Shares of LC Suppliers, 2007 (percent)
  • Corporate Profiles
    • AGILENT TECHNOLOGIES
    • BIO-RAD
    • DIONEX
    • EKSIGENT TECHNOLOGIES
    • ESA BIOSCIENCES
    • GE HEALTHCARE
    • GRACE DAVISON DISCOVERY SCIENCES (W.R. GRACE & CO.)
    • HITACHI HIGH TECHNOLOGIES
    • PROXEON BIOSYSTEMS
    • SHIMADZU
    • THERMO FISHER SCIENTIFIC
    • VARIAN
    • WATERS CORP.
  • Challenges and Strategic Recommendations
    • CHALLENGES
      • Advances in Competing Technologies Erode Growth
      • Clinical Applications Require Adjustment for Companies
      • Diminishing Returns in Ultra and Fast LC Technologies
      • Precedence in Purchasing Decisions
      • Routine Applications Demand Different Types of Systems
      • Customers' Experiencing Budget Restrictions or Flat Funding
      • Customers' Uncertainty Regarding UHPLC and Fast LC
    • STRATEGIC RECOMMENDATIONS
      • Position for Shift Towards Protein Therapeutics
      • Expand into Related Applications and Products
      • Incorporate or Enable Green Features
      • Address Broader Mass Spectometry Adoption
      • Target Niche Applications Through Differentiation of Products
      • Strengthen and Emphasize Service and Support
      • Increase User-Friendliness and Standardization of Software

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