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Gene Amplification Technologies: End Users, Marketers, and Markets

Gene amplification technology has been a backbone technology for the Human Genome Project and is vital in other fields, such as diagnostics. There are more than 50 biotech and diagnostic companies with DNA amplification technology and approximately 30 different gene- and signal-amplification technologies, from polymerase chain reaction to ligase chain reaction, transcription mediated amplification, and dendritic polymers. And these many technologies are being used for an ever-increasing variety of applications in research and clinical settings.

The market for amplification technology is currently in the hundreds of millions of dollars, but as the need for information about genes in genomics and other research progresses, and as clinical diagnostic tools develop, the market for amplification technology will continue to grow. Although PCR is currently the dominant amplification technology, other technologies are emerging to challenge PCR in many areas. Patents, costs, and ease of use of a technique are forces that drive the development of amplification technology and will shape this dynamic market.

This study reviews the landscape in this emerging sector, discussing technologies, applications, competitors, and regulation. In addition, Kalorama has conducted the first ever end-user survey, to determine the preferences of actual researchers using various amplification technologies in various settings and for various applications.


Gene Amplification Revenues to Surpass $1.6 Billion by 2007

New York, August 6, 2002 /PR Newswire — Applications and revenues will continue to expand for gene amplification technologies, according to a new study released today from Kalorama Information. The study found that total revenues for the top ten amplification technologies will grow by more than 50% from their current levels to surpass $1.6 billion in 2007.

The new study, Gene Amplification Technologies: End Users, Marketers, and Markets, also found that although the polymerase chain reaction (PCR) has long been the dominant technology in the field, it is no longer the only one deriving significant revenues. According to the report, several other techniques, including OmniPlex (Rubicon Genomics), SDA (Becton Dickinson), LCR (Abbott/ImClone), and Hybrid Capture (Digene), are growing at double-digit rates and making progress in specific applications.

In addition to quantifying the market, part of the study involved surveying the attitudes of end-users working with amplification techniques. The study sought to define some of the strategies marketers will need to adopt to compete in a PCR-dominated field that is nonetheless experiencing dynamic technical advancement. Researchers are beginning to use different technologies for some applications, according to the results, but the lack of robust technical trouble-shooting experience was a major drawback for many non-PCR techniques.

“Isothermal DNA amplification techniques, such as rolling circle, are attractive because they would be faster and do not require the use of a thermocycler machine,” notes Laura Ruth, PhD, the author of the study. “However, users indicated that they are wary because not as much is known about isothermal DNA amplification techniques.”

The study discusses trends in target versus signal amplification, isothermal versus cycling temperature, and exponential versus linear technologies, as well as the future of the field and the potential development of chip-based technologies.

About Kalorama Information
Kalorama Information, an imprint of MarketResearch.com, supplies the latest in independent market research for the life sciences. For more information, contact Steven Heffner at 212-807-2634 or sheffner@kaloramainformation.com.

About MarketResearch.com
MarketResearch.com is the leading provider of global market intelligence products and services. With over 50,000 research publications from 350 research publishers, they offer instant online access to the world’s most extensive database of expert insights on global industries. Updated daily. For more information, contact Kim Bolus at 212-807-2655 or kbolus@marketresearch.com.

  • Executive Summary
    • Introduction
    • Scope And Methodology
    • Summary Of Major Findings
  • The Technologies
    • Target Vs. Signal Amplification
      • Table Gene Amplification Technology Summary
      • Target Amplification Technology Glossary
        • Table Comparison Of Rcat With Pcr By Feature
      • Signal Amplification Technology Glossary
      • Other Amplification Technology Glossary
    • Isothermal Vs. Cycling Temperature
      • Table Summary Of Isothermal & Cycling Gene Amplification Technologies
      • Table Advantages/Disadvantages Of Isothermal And Cycling Dna Amplification Techniques
      • Isothermal Dna Amplification Technologies
      • Cycling Temperature Dna Amplification Technologies
      • Isothermal Signal Amplification Technologies
      • Cycling Other Gene Amplification Technologies
    • Exponential Vs. Linear Dna Amplification Techniques
      • Table Advantages & Disadvantages: Exponential Versus Linear Dna Amplification Techniques
      • Exponential Gene Amplification
      • Linear Gene Amplification
    • Trends In Gene Amplification Technologies Development
      • Table Gene Amplification Technologies Physical Characteristic And Development Date Summary
      • Additional Properties: Sensitivity, Range, Specificity
        • Table Range, Sensitivity, & Specificity Gene Amplification Properties
    • Amplification Technology Market Players
      • Table Amplification Technology Research-Only Companies
      • Table Amplification Technology Application-Only Companies
      • Table Amplification Technology Research & Application Companies - Part 1
      • Table Amplification Technology Research & Application Companies - Part 2
  • The Markets
    • Amplification Technology Revenue
      • Table Gene Amplification Technology Sales
    • Amplification Technology Market Share
      • Market Share By Competitor
        • Table Gene Amplification Technology Market Share By Competitor
      • Target Vs Signal Gene Amplification Technology
        • Table Target Vs. Signal Gene Amplification Technology Revenue
      • Cycling Vs Isothermal Gene Amplification Technology Revenue
        • Table Cycling Vs Isothermal Gene Amplification Technology Revenue
      • Exponential Vs Linear Gene Amplification Technology Revenue
        • Table Exponential Vs Linear Gene Amplification Technology Revenue
  • The Applications
    • Introduction
    • Medical Applications
      • Fda-Regulated Molecular Diagnostic Tests
        • Table Technology Used In Fda Approved Molecular Diagnostic Tests
        • Table Fda-Approved Clinical Molecular Diagnostic Test By Technology And Company
        • Table Pcr Fda-Approved Molecular Diagnostic Tests And Companies
        • Table Tma Fda-Approved Molecular Diagnostic Tests And Companies
        • Table Hybrid Capture Fda-Approved Molecular Diagnostic Tests And Companies
        • Table Nasba Fda-Approved Molecular Diagnostic Tests And Companies
        • Table Fda-Approved Clinical Molecular Diagnostic Tests By Disease
        • Table Fda-Approved Chlamydia Tests
        • Table Fda-Approved Gonorrhea Tests
        • Table Fda-Approved Hiv & Hcv Tests
    • Forensics, Paternity, Identity
    • Food Safety, Agri-Diagnostics
    • Veterinary
  • The Reign Of Pcr-The Pcr Patent Fort
  • Dna Amplification Technologies End-User Survey
    • Summary Of Results
    • Conclusions
  • Next Generation: Dna Amplification On a Chip
  • Conclusions And Strategic Implications
    • First Conclusion
    • Second Conclusion
    • Third Conclusion
    • Fourth Conclusion
  • Company Profiles
    • Abbott Laboratories
    • Agilent Technologies
    • Ambion, Inc.
    • Amersham Biosciences, Inc.
    • Axcell Biosciences
    • Bayer Corporation
    • Becton, Dickinson, And Co.
    • Biogenex
    • Biotecon Diagnostics
    • Bio Merieux
    • Caliper Technology Corporation
    • Cepheid
    • Chugai Biopharmaceuticals, Inc.
    • Cytocell, Ltd.
    • Cytogen Corporation
    • Digene Corporation
    • Eragen Biosciences, Inc.
    • Exiqon, Inc.
    • Genisphere 3Dna
    • Gen-Probe
    • Hamilton Thorne Biosciences
    • Hibergen Limited
    • Id Biomedical Corporation
    • Imclone Systems, Inc.
    • Linco Research, Inc.
    • Molecular Sensing, Plc
    • Molecular Staging, Inc.
    • Nanogen, Inc.
    • Orchid Biosciences, Inc.
    • Perkinelmer Life Sciences
    • Phylogenetix Laboratories, Inc.
    • Qbiogene
    • Rubicon Genomics
    • Signalgene, Inc.
    • Takara Shuzo Co., Ltd.
    • Third Wave Technologies
    • Tm Bioscience Corporation
    • U.S. Genomics
    • Xtrana, Inc.
  • Dna Amplification Techniques End-User Questionnaire
  • Company Directory

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