Endometriosis - Drug Pipeline Landscape, 2023

Endometriosis - Drug Pipeline Landscape, 2023

Endometriosis is a disorder in which tissues similar to, but not the same as, the lining of the uterus are found elsewhere in the body. The lining of your uterus is called the endometrium. Endometriosis occurs when endometrial-like tissue grows on your ovaries, bowel, and tissues lining your pelvis.

The exact cause of endometriosis unknown. Explanations of possibility include retrograde menstruation, transformation of embryonic cell, transformation of peritoneal cells, surgical scar implantation and endometrial cell transport.

Endometriosis patients may have symptoms of menstrual cramps, abdominal pain or back pain, infertility, painful bowel movements, vaginal bleeding, pain with intercourse and other signs and symptoms include fatigue, diarrhea, constipation, bloating or nausea.

Diagnosis of endometriosis includes pelvic exam, ultrasound, magnetic resonance imaging and laparoscopy.

Treatment of endometriosis include medication or surgery. Therapies used to treat endometriosis include hormonal contraceptives, gonadotropin-releasing hormone (Gn-RH) agonists and antagonists, progestin therapy and aromatase inhibitors. Surgical options include laparoscopy and hysterectomy.

The companies active in the development of endometriosis drugs are Aptorum., Bayer AG, Chugai Pharmaceutical, Ferring Pharmaceuticals etc.

Major pharmaceutical companies are involved in the development of potential drug candidates to improve the Endometriosis treatment such as DLBS1442, HMI-115, OBE2109 and others. Key players involved in the development of therapies to treat Endometriosis are Dexa Medica Group, Enteris BioPharma Inc, Hope Medicine (Nanjing) Co Ltd, Mitsubishi Tanabe Pharma Development America Inc, ObsEva SA and others. Two drugs are under late-stage Phase III clinical trials and ten drugs are in Phase II clinical trials and some other drugs are under Phase I, preclinical and discovery stages of development.

Report Highlights

Global Insight Service's, Endometriosis - Drug Pipeline Landscape, 2023 report provides an overview of the Endometriosis pipeline drugs. This report covers detailed insights on Endometriosis drugs under development, assessment by target, mechanism of action, route of administration and molecule type. Product pipeline by companies, stage of development and key regulatory designations, deals and milestones have been presented to provide insights and thus help industry participants in their decision making. Endometriosis pipeline report helps gain insights on drugs which are under development stage of drug development process across globally.

Methodology

The research process includes extensive secondary research on public domain and other authentic sources to add or update the pipeline products information. The secondary research sources include, but are not limited to company websites, annual reports, financial reports, company pipeline chart, investor presentations and SEC filings, journals and conferences, and clinical trials registries.

Scope

The pipeline landscape report provides analysis of pipeline products based on several stages of development ranging from Discovery to Pre-Registration. The report provides a review of pipeline therapeutics by companies based on information derived from company and industry-specific sources. The pipeline report covers assessment of therapeutics by mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. Comprehensive profiles of the pipeline products with details such as company overview, development stage; molecule type, target, mechanism of action, route of administration, dosage form, regulatory designations, key deals, clinical trials, and key upcoming milestones are included.

Reasons to Buy
Helps to find and recognize significant therapeutics under development. Thorough understanding of pipeline structure and helps in developing corrective measures for pipeline projects.
Effective R&D strategies can be developed with deep knowledge of competitor information, analysis, and insights.
Plan collaborations with various industry partners that have role in some or the other stage of drug development such as contract manufacturing, co-development, contract research organization and commercialization etc.
Helps to create in-licensing and out-licensing opportunities by identifying prospective partners with attractive projects to expand business potential and scope.

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