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Neural Stem & Progenitor Cell Products - Strategic Development

Technically speaking, “neuronal” means “pertaining to neurons”, and “neural” means “pertaining to nerves, which are the cordlike bundles of fibers made up of neurons.” Since both terms ultimately are descriptive of neurons, the scientific community uses the terms "neuronal" and "neural" interchangeably. The complexity of this issue is explored from a marketing perspective within this report.

Over the past few years, neuronal stem and progenitor cells have become of profound interest to the research community due to their potential to be used in drug discovery and delivery applications, as well as for tools of neural toxicology assessment. NSC transplantation also represents a ground-breaking approach for treating a range of chronic neurological diseases and acute CNS injuries, including Parkinson’s, Alzheimer’s and spinal cord injury, among other conditions.

This market report focuses on recent advances in NSC research applications, explores research priorities by market segment, highlights individual labs and end-users of neuronal stem cell research products, explores the competitive environment for NSC research products, and provides 5-year growth and trend analysis. It provides detailed guidance for companies that wish to offer strategically positioned NSC research products, including cells, kits, assays, and related media and reagents.

I. Background
A. Language and Definitions
1. Neurogenesis
2. Neuronal vs. Neural
3. Neural Stem Cells (NSCs) vs. Neural Progenitor Cells (NPCs)
B. Brief History
C. Overview of Neural Stem and Progenitor Cell Regulation
1. In vitro Regulation
2. In vivo Regulation
D. Product Background
II. Applications
A. Basic Research
1. Developmental Biology
2. Adult Biology
B. Drug Discovery Applications
C. Drug Delivery Applications
D. Neural Toxicology Assessment
E. Neural Transplantation
F. Brain Tumor Research
III. Application Priorities
A. Overall
1. Cell-Based Therapies
2. Standardized Neural Toxicology Assays
B. Breakdown of Neural Stem Cell Research by Disorder
C. By Segment
1. Academic
2. Biotech
3. Pharma
IV. Patents
A. Key U.S. Neuronal Stem and Progenitor Cell Patents
B. Additional U.S. Patents
C. Additional European Patents
V. Projected 5-Year Market Growth
A. Scientific Publication Analysis
1. Neural vs. Neuronal Products
2. Stem vs. Progenitor Cell Products
3. Five-Year Growth Projections
4. Conclusions from Data
B. Grant Rate Analysis
1. Neural vs. Neuronal Products
2. Stem vs. Progenitor Cell Products
3. Five-Year Growth Projections
4. Conclusions from Data
C. Patent Rate Analysis
1. Neural vs. Neuronal Products
2. Stem vs. Progenitor Cell Products
3. Five-Year Growth Projections
4. Conclusions from Data
VI. Competitors: Suppliers of Neural Stem & Progenitor Cell Products, Including Products Offered
A. Millipore, Inc.
B. Stem Cell Technologies
C. AlphaGenix, Inc.
D. R&D Systems
E. Cell Applications
F. SA Biosciences
G. ScienCell
H. Neuromics
I. Amaxa
J. Invitrogen
K. Sigma Aldrich
L. Orion (no longer in existence)
VII. Specialty Pharmaceutical Companies: Neural Stem & Progenitor Cell Therapies
A. Neuralstem, Inc
B. NeuroNova AB
C. NeuroGeneration
VIII. Breakdown of Stem Cell Research Activity by Cell Type
IX. Potential End-Users of Neural Stem Cell Products
A. Academic Labs
B. Private Labs
C. Commercial Labs
D. Government Labs
X. Product Ideas & Suggestions
A. Product Categories
1. Cells & Tissue
a. Fetal-Derived Neural Stem Cells
b. Adult-Derived Neural Stem Cells
c. Fetal-Derived Immortalized Neural Stem Cells
d. Cryopreserved Embryonic Neurospheres
e. Embryonic Stem Cell Derived Neural Progenitors
f. Embryonic Primary Neuronal Tissue
g. NSC Differentiated Progeny Cells
2. Kits
a. Kits for Analysis of NSC Differentiated Progeny
b. Stem Cell Functional Kits
c. Neuronal Stem Cell Phenotyping Kits
d. Neural Stem Cell Expansion Kits
e. Neural Stem Cell Differentiation Kits
f. Neural Stem Cell Blotting Kits
3. Media: Maintenance, Differentiation, Expansion, & Freezing Medium
4. Growth Factors
5. Markets: Markers for Neural Stem Cells & Differentiated Progeny
6. PCR Arrays
7. Nucleofection Tools
8. Neural Toxicity Assessment
B. Product Suggestions
1. Neural Toxicity Assessment Products (an untapped niche)
2. Species-Specific Opportunities
3. Areas of Underdeveloped Competition
4. NSC Derived from Novel Sources
5. Neural Rosette Cells (R-NSCs)
XI. Conclusions

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