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The Global Market for Pain Management Drugs and Devices

The Global Market for Pain Management Drugs and Devices

Report Highlights
The global market for pain management will grow from nearly $36.1 billion in 2017 to $52.0 billion by 2022, with a compound annual growth rate (CAGR) of 7.6% for the period of 2017-2022.
Report Includes
An overview of the global market for pain management drugs, which will address acute vs. chronic pain, treatments, and issues facing healthcare workers
Analyses of global market trends, with data from 2015 and 2016, estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022
Examination of product categories, use of products, and the competitive landscape
Coverage of several significant market trends, including undertreatment issues, professional issues, managed care pain issues, trends in new therapies, product pipelines, generic participation, pain research, drug delivery, and patent expirations
Discussion of new regulatory requirements
Comprehensive company profiles of major players in the industry

Report Scope
This BCC Research report is designed to be a helpful business tool that will provide a thorough evaluation of the markets for pain management. The geographical scope of this study is global. This study will address acute versus chronic pain, treatments and regulatory issues facing healthcare workers. Also provided is detailed information based on product categories, use of products, forecasts and competitive analyses.

The report identifies two general segments of pain management:
Pharmaceuticals.
Devices.

Within the pharmaceuticals segment several sub-segments are discussed in detail including:
Narcotic pain management.
Non-narcotic pain management.
Antimigraine treatments.
Anesthetics.
Other drugs (including CNS therapies).

The device segment covers several product lines and specifically targets the largest product segments including:
Electrotherapy stimulators.
Spine stimulators.
Other products (including electromagnetic therapies and other treatments).

Each market segment provides detailed information based on product categories, product use, forecasts and competitive analyses.

Not covered in the report are drugs or devices that by treating the condition or disorder result in the relief of pain. These include treatments for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis or other similar diseases. Treatments are only included for those that indicate a relief of pain symptoms associated with these conditions.

A comparison of a treatment for the disease that naturally relieves the symptoms as compared to treatments for the relief of pain associated with the disease include:

Enbrel : Indicated for the treatment of moderate-to-severe rheumatoid arthritis.
Celebrex : Indicated for the treatment of the signs and symptoms of osteoarthritis and rheumatoid arthritis and the management of acute pain.

The report is also evaluated in terms of application, discussing market trends and performance for the following areas:
Surgical pain.
Orthopedic/musculoskeletal pain.
Migraine pain.
Fibromyalgia pain.
Cancer pain.
Neuropathic pain.
HIV/AIDS pain.
Dental pain.
General pain.


Chapter 1: Introduction
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Methodology and Information Sources
Geographic Breakdown
Analyst’s Credentials
Related BCC Research Reports
Chapter 2: Summary and Highlights
Overview
Summary of the Major Markets
Market Trends
Undertreatment Issues
Professional Pain Treatment Issues
Access to Care
FDA Requirements for Approval of Pain Therapies
Drug Delivery Systems
Chapter 3: Market and Technology Background
History of Pain and Pain Treatment
The Perception of Pain
Types of Pain
Acute Pain
Chronic Pain
Assessment of Pain
Subjective
Objective
How Pain is Diagnosed
How Pain is Treated
Demographics and Aging Populations
Global Demographic Overview
Gender and Pain
Other Influences Determining How Pain is Felt Among Individuals
Pain Management Procedures: Steroids, Endoscopy, Fluoroscopy
Alternative Methods of Pain Management
Growing Trend in Cannabis Treatment for Pain
Physical Pain Treatment Modalities
Acupuncture/Acupressure
Ice (Cryotherapy)
Joint Mobilization
Manipulation
Massage
Traction
Radiation Therapy
Radio-Frequency Neuroablation, Epiduroscopy
Surgery
Whirlpool Bath (Thermotherapy)
Psychological Pain Therapies
Biofeedback
Hypnosis
Behavior Modification/Operant Conditioning
Relaxation and Stress Management Training
Imagery
Autogenic Training
Psychosocial Interventions
Distraction and Reframing
Tracking the Development of Complementary and Alternative Pain Control Methods
Pain Management Services and Organizations
Home Care
Hospice
Hospitals
Pain Clinics
Skilled Nursing Facilities
Chapter 4: Industry Trends
Overview
Undertreatment Issues
Treatment of Pain and Issues Facing the Professional Segment
Prescription Drug Monitoring Programs
Access to Care
Managed Care Pain Management Issues
FDA Approval of Pain Therapies
FDA Approval of Pain Devices
Risk Evaluation and Mitigation Strategy (REMS)
Acetaminophen and FDA Changes
Codeine in Cough and Cold Medications
NSAIDs Linked to Increased Risk of Heart Attack or Stroke
Drug Delivery Systems
Chapter 5: Treating Pain: Markets by Product Type
Overview
Pharmaceutical Pain Management
Prescription Pain Management Products
Total Market
Narcotic Analgesics
Non-narcotic Analgesics
Antimigraine Agents
Anesthetics
Other Drug Classes
Pain Management Devices
Pain Management Device Market
Total Market
Stimulation Therapy
Combination Pain Management Devices
Chapter 6: Market Breakdown by Application
Pain Management by Application
Surgical Pain Management
Orthopedic/Musculoskeletal Pain Management
Fibromyalgia Pain
Cancer Pain Management
Neuropathic Pain
HIV/AIDS Related Pain
Burn Pain
Dental Pain
Chapter 7: Market Breakdown by Region
Global Health Indicators
Health Expenditures and GDP Review
Average Length of Stay
Public Healthcare Systems Around the World
Markets by Global Region
North America
Europe, Middle East, Africa (EMEA)
Asia-Pacific
Latin America
Chapter 8: Industry Developments
Timeline of Significant Industry Events and Developments
Pharmaceutical Pipeline
Pain Device Clinical Trials
Patent Analysis
Patent Review by Year
Patent Review by Type
Patent Review by Company
Patent Review by Country
Patent Review by Assignee
Drug Patents for Selected Therapies
The Brand/Generic Market Split
Future of Pain Research
Pain Research: Pediatric Populations
Patient Outcomes Research
Selected Pain-related Acquisitions and Alliances
Chapter 9: Analysis of Market Opportunities
Total Pain Management Market
Markets by Type
Markets by Application
Markets by Global Region
Chapter 10: Company Profiles
Appendix A: Terminology and Sources of Information
Pain Management Pharmaceutical Manufacturers and Developers
U.S. Pain Societies and Associations
International Associations and Organizations
About BCC Research
About BCC Research
BCC Membership
BCC Custom Research
List of Tables
Summary Table: Global Market for Pain Management, by Major Segment, Through 2022 ($ Millions)
Table 1 Objective Signs of Pain
Table 2 Global Population Growth, by Select Country, 2015 and 2020 (Millions)
Table 3 Global Population Growth, by Age Group, Through 2050 (Millions)
Table 4 Global Life Expectancy at Birth, by Select Country, 1980-2020 (Years)
Table 5 Pain by Select Category and Gender in the Age 18+ U.S. Population,* 1997-2010 (Thousands) .. 31
Table 6 U.S. Medical Marijuana Programs, by State
Table 7 Effectiveness of Fibromyalgia Treatments: Cannabis vs. Pharmaceutical Therapies, 2014 (%)
Table 8 Use of Complementary and Alternative Medicine Among U.S. Adults, by Type of Therapy, 2002–
2015 (Thousands)
Table 9 Percentage of U.S. Hospice Patients, by Gender and Age Group, 2009–2014
(%)
Table 10 Percentage of Hospice Admissions, by Primary Diagnosis, 2009–2014 (% of Total)
Table 11 NHPCO Committees
Table 12 Definition of Pain Clinics
Table 13 Desirable Characteristics of Pain Clinics, by Type
Table 14 Registered Pain Clinics in the United States, by Top Metro Area, 2016 (Number)
Table 15 Registered Pain Clinics, by Country (Number)
Table 16 Availability of Education in Pain Management, by Select Region/Country
Table 17 Agency Responsible for PDMP in Each State
Table 18 Benefits of Prescription Monitoring Programs for Medical Boards
Table 19 Drugs Monitored by PDMPS, as of June 2017
Table 20 States with Electronic Prescription Monitoring Programs, as of June 2017
Table 21 Nurse Continuing Education Requirements for Pain Management, by Requiring State
Table 22 WHO List of Essential Medicines for Adult Pain Management
Table 23 Availability of Injectable Morphine, by Region/Country
Table 24 Availability of Oral Morphine in Hospice-Type Settings, by Region/Country
Table 25 FDA Analgesia/Anesthesia Drug Shortages, June 2017
Table 26 Parts 862–892 of 21 CFR
Table 27 List of Extended-Release and Long-Acting Opioid Products Subject to Opioid REMS, by Brand
Name Product, May 2017
Table 28 List of Extended-Release and Long-Acting Opioid Products Subject to Opioid REMS, by Generic
Product, May 2017
Table 29 List of Products Subject to the TIRF REMS Access Program, 2011–2016
Table 30 List of NSAIDs
Table 31 Advantages of Iontophoretic Drug Delivery
Table 32 FDA Applications/Approvals, Jan. 2010 Through Jan. 2017
Table 33 Global Market for Prescription Pain Management Pharmaceuticals, by Product, Through 2022
($ Millions)
Table 34 Most Commonly Used General Anesthetic Agents
Table 35 Global Market for Pain Management Devices, by Technology Type, Through 2022 ($ Millions)
Table 36 Global Market for Pain Management, by Application, Through 2022 ($ Millions)
Table 37 Global Market for Surgical Pain Management, by Product Type, Through 2022 ($ Millions)
Table 38 Birth Rates and Births, by Country, 2016 and 2025 (Thousands)
Table 39 Global Market for Orthopedic/Musculoskeletal Pain Management, by Product Type, Through
2022 ($ Millions)
Table 40 Global Market for Migraine/Headache Pain Management, by Product Type, Through 2022 ($
Millions)
Table 41 Global Market for Fibromyalgia Pain Management, by Product Type, Through 2022 ($ Millions)
Table 42 Cancer Pain Medication
Table 43 Global Market for Cancer Pain Management, by Product Type, Through 2022 ($ Millions)
Table 44 Global Market for Neuropathic Pain Management, by Product Type, Through 2022 ($ Millions)
Table 45 Global Market for HIV/AIDS Pain Management, by Product Type, Through 2022 ($ Millions) . 180
Table 46 Global Market for Burn Pain Management, by Product Type, Through 2022 ($ Millions)
Table 47 Global Market for Dental Pain Management, Through 2022 ($ Millions)
Table 48 Health Expenditures as a Percentage of GDP, by Select Country, 1980–2015 (%)
Table 49 Average Hospital Length of Stay, by Select Country, 1970–2015 (Days)
Table 50 World Health Organization Ranking of Healthcare Systems, 2000
Table 51 Major Countries, by Region
Table 52 Global Market for Pain Management, by Region, Through 2022 ($ Millions)
Table 53 North American Market for Pain Management, by Application, Through 2022 ($ Millions)
Table 54 EMEA Market for Pain Management, by Application, Through 2022 ($ Millions)
Table 55 Asia-Pacific Market for Pain Management, by Application, Through 2022 ($ Millions)
Table 56 Latin America Market for Pain Management, by Application, Through 2022 ($ Millions)
Table 57 Select Pain Management Drug Pipelines
Table 58 Selected Pain Management Device Trials
Table 59 U.S. Patents on Pain Treatments, Issued, by Year, Jan. 2000 Through March 2017 (Number) . 214
Table 60 Number of U.S. Patents on Pain Technologies, by Abstract Description
Table 61 U.S. Patents on Recent Pain Technologies, March 21, 2017-April 18, 2017
Table 62 U.S. Patent Expiration Dates for Select Pain Drugs
Table 63 First Time Prescription Generic Pain Management and Approvals, April 2005-June 2017
Table 64 Pain or Pain-related Clinical Trials, by Region, 2017
Table 65 Market Opportunities for Pain Management Treatments, Through 2022
Table 66 Global Market for Pain Management, by Major Type, Through 2022 ($ Millions)
Table 67 Global Market for Pain Management, by Application, Through 2022 ($ Millions)
Table 68 Global Market for Pain Management, by Region, Through 2022 ($ Millions)
Table 69 Abbott Laboratories Financials, Through 2016 ($ Millions)
Table 70 AbbVie Financials, Through 2016 ($ Millions)
Table 71 Allergan Financials, Through 2016 ($ Millions)
Table 72 AstraZeneca Financials, Through 2016 ($ Millions)
Table 73 Boston Scientific Financials, Through 2016 ($ Millions)
Table 74 Depomed Financials, Through 2016 ($ Millions)
Table 75 DJO Global financials, Through 2016 ($ Millions)
Table 76 Eli Lilly & Co. Financials, Through 2016 ($ Millions)
Table 77 Endo International Financials, Through 2016 ($ Millions)
Table 78 GlaxoSmithKline Financials, Through 2016 ($ Millions)
Table 79 Grünenthal Financials, Through 2016 ($ Millions)
Table 80 Hisamitsu Pharmaceutical financials, Through Fiscal 2017 ($ Millions)
Table 81 Johnson & Johnson Financials, Through 2016 ($ Millions)
Table 82 Medtronic Financials, Through Fiscal Year 2016 ($ Millions)
Table 83 Novartis Financials, Through 2016 ($ Millions)
Table 84 Pfizer Financials, Through 2016 ($ Millions)
Table 85 Glossary of terms used in Pain Management Drug and Device Markets
Table 86 Pain Management Pharmaceutical Manufacturers and Developers
Table 87 U.S. Pain Societies and Associations
Table 88 International Associations and Organizations
List of Figures
Summary Figure: Global Market for Pain Management, by Major Segment, 2014–2022 ($ Millions)
Figure 1 Pain Management Techniques
Figure 2 Global Population, by Select Country, 2015 and 2020 (Millions)
Figure 3 Global Population Growth, by Age Group, 2000–2050 (Millions)
Figure 4 Global Life Expectancy at Birth, 1980-2020 (Years)
Figure 5 Pain by Select Category and Gender in the 18+ U.S. Population,* 1997-2010 (%)
Figure 6 Use of Complementary and Alternative Medicine Among U.S. Adults, by Type of Therapy,
2002–2015 (Thousands)
Figure 7 Annual Number of U.S. Hospice Patients, 2009–2014
Figure 8 Percentage of U.S. Hospice Patients, by Gender, 2014 (%)
Figure 9 Percentage of U.S. Hospice Patients, by Age Group, 2014 (%)
Figure10 Distribution of Causes of Mortality and Potential Need for Palliative Care (Millions)
Figure 11 Distribution of Narcotic Drug Consumption, by Country (All Narcotic Types) (%)
Figure 12 Distribution of Morphine Consumption by Region/Country, 2015 (%)
Figure 13 Obstacles to Availability of Opioids for Medical Needs (Number)
Figure 14 Global Market for Prescription Pain Management Pharmaceuticals, by Product, 2014–2022 ($
Millions)
Figure 15 Global Market Distribution for Narcotic Analgesics, by Ingredient*, 2017 (%)
Figure 16 Global Market Distribution for Non-Narcotic Analgesics, by Ingredient*, 2017 (%)
Figure 17 Global Market Distribution for Antimigraine Agents, by Ingredient*, 2017 (%)
Figure 18 Global Market Distribution for Anesthetics, by Ingredient*, 2017 (%)
Figure 19 Global Market for Pain Management Devices, by Technology Type, 2014–2022 ($ Millions) . 153
Figure 20 Global Market for Pain Management, by Application, 2014–2022 ($ Millions)
Figure 21 Global Market for Surgical Pain Management, by Product Type, 2014–2022 ($ Millions)
Figure 22 Births, by Country, 2016 and 2025
Figure 23 Arthritis Impact, Global Prevalence, by Year, 2000–2050
Figure 24 Global Cancer Mortality by Select Country per 100,000 Population, 1960–2020
Figure 25 Causes of Cancer Pain
Figure 26 Burn Pain Management Approach
Figure 27 Health Expenditures as a Percentage of GDP, by Select Country, 1980–2015 (%)
Figure 28 Global Market for Pain Management, by Region, 2014–2022 ($ Millions)
Figure 29 Pain Management Drug Pipeline, by Development Status (Number)
Figure 30 Pain Management Drug Pipeline, by Primary Indication (Number)
Figure 31 Pain Management Devices in Development, by Development Status (%)
Figure 32 Shares of U.S. Patents on Pain Technologies, by Three-Year Date Range, Jan. 2000-March 2017
(%)
Figure 33 Shares of U.S. Patents on Pain Technologies, by Abstract Description (%)
Figure 34 Patent Shares of Pain Technologies (%)
Figure 35 Global Market for Pain Management Pharmaceuticals, by Actual and Projected Brand vs.
Generic Sales Performance, 2012–2022 ($ Millions)
Figure 36 Distribution of Pain-related Clinical Trials for All Ages, by Region, 2017 (%)
Figure 37 Distribution of Pain-related Clinical Trials for Pediatrics, by Region, 2017 (%)
Figure 38 Global Market for Pain Management, 2015–2022 ($ Millions)
Figure 39 Global Market for Pain Management, by Major Type, 2014–2022 ($ Millions)
Figure 40 Global Market for Pain Management, by Application, 2014–2022 ($ Millions)
Figure 41 Global Market for Pain Management, by Region, 2014–2022 ($ Millions)

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