Exosome Diagnostics and Therapeutics: Global Markets
Report Scope:
This report represents a current and important business tool to evaluate new commercial opportunities in the exosome diagnostic, therapeutic and research tool markets. The geographic scope of this study covers the U.S. and companies worldwide. This market is complex and consists of a number of different sectors, each affected differently by scientific and technological development. The report identifies the main positive and negative factors in each sector and forecasts further trends and product and assay development in every category of this industry.
Report Includes:
- 109 tables
- An updated review of the global market for exosome diagnostics and therapeutics within the biotech research industry
- Analyses of the global market trends, with data from 2019-2020, estimates for 2021, and projections of compound annual growth rates (CAGRs) through 2026
- Estimation and forecast the overall global market size, and corresponding market share analysis by application, end-user, and geographic region
- Description of immunological compatibility, cargo capabilities and other intrinsic therapeutic activities of exosomes
- Evaluation of exosome proteins and nucleic acids as diagnostic biomarkers and discussion of their impact on microRNA, liquid biopsy and stem cell research industry
- Information on bioinformatics databases for exosome research and product development, including as ExoCarta, Vesiclopedia and EVpedia
- Impact of exosome research on specific biopharmaceutical market and summary of details for major companies researching and producing exosome products
- A relevant patent analysis on Exosome Diagnostics and Therapeutics in the U.S., Europe and Japan
- Competitive landscape of the major players operating within global market, and their global rankings and company share analysis
- Profile descriptions of the leading vendor companies including Codiak BioSciences, Evox Therapeutics, Exosome Diagnostics Inc., NonoSomiX Inc., and System Biosciences
- Chapter 1 Introduction
- Study Goals and Objectives
- Reasons for Doing This Study
- Scope of Report
- Information Sources
- Methodology
- Intended Audience
- What's New in This Report?
- Geographic Breakdown
- Analyst's Credentials
- BCC Custom Research
- Related BCC Research Reports
- Chapter 2 Summary and Highlights
- Chapter 3 Market and Technology Background
- Exosome Definition and Nomenclature
- Discovery of Exosomes
- Exosomes Biogenesis and Processing
- Exosome Components
- DNA in Exosomes
- Proteins in Exosomes
- RNA in Exosomes
- Isolation and Detection of Exosomes
- Isolation Techniques
- Exosome Detection
- Bioinformatic Databases for Exosome Research and Product Development
- ExoCarta
- Vesiclepedia
- EVpedia
- Exosome Function and Physiology
- Chapter 4 Impact of COVID-19 on the Exosome Therapeutics Market
- Overview
- Current Outlook
- Exosome and COVID-19 Treatment
- Chapter 5 Exosome Diagnostics Market
- Exosomal Proteins as Diagnostic Biomarkers
- Exosomal Nucleic Acids as Diagnostic Biomarkers
- Cancer Diagnostics as Market Potential for Exosome-Based Diagnostic Product Development
- Prostate Cancer Diagnostics Development in the Exosome Sector
- Breast Cancer as Potential for Diagnostic Development in the Exome Sector
- Bladder Cancer as Potential for Diagnostic Development in the Exosome Sector
- Ovarian Cancer as Potential for Diagnostic Development in the Exome Sector
- Lung Cancer as Potential for Diagnostic Development in the Exosome Sector
- Liquid Biopsy as Potential for Diagnostics in the Exome Sector
- Exosomal Proteins and Nucleic Acids as Cancer Biomarkers in Assay Development
- CNS Disorders and Neurodegeneration Diseases as Market Potential for Exosome Diagnostics Product Development
- Infectious Diseases as Market Potential for Exosome Diagnostic Product Development
- Cardiovascular Diseases as Market Potential for Exosome Diagnostic Product Development
- Prenatal Testing as Market Potential for Exosome Diagnostic Product Development
- Organ Transplantation as Market Potential for Exosome Diagnostic Product Development
- Market Participants in the Exosome-Based Diagnostics Sector
- Companies
- Evaluation of the Current Diagnostics Sector in the Exosome Market
- Chapter 6 Exosome Therapeutics Market
- Intrinsic Therapeutic Activity of Exosomes
- Immunological Compatibility
- Cargo Capabilities
- Generation of Exosome-Mediated Therapeutics
- Exosome Isolation and Purification from Biofluids or Cell Culture
- Engineering Exosomes as Therapeutic Delivery Vehicles
- Targeting Exosomes to Specific Recipient Cells
- Designing Exosomes as a Synthetic Vector
- Market Potential for Exosome Therapeutics
- Market Participants in the Exosome-Based Therapeutics Sector
- Companies
- Evaluation of the Current Therapeutics Sector in the Exosome Market
- Chapter 7 Exosome Reagents and Research Tools Market
- Market Overview
- Isolation Methodologies and Reagents for Exosome
- Detection Methodologies and Reagents for Exosome Research
- Characterization Methods and Reagents for Exosome Research
- Engineering Methods and Reagents for Exosome Research
- Additional Products and Reagents for Exosome Research
- Market Participants in Reagents and Tools for Exosome Research
- Companies
- Evaluation of Current Tools and Reagents in the Exosome Market
- Chapter 8 Global Exosome Therapeutic and Diagnostics Market by End User
- Cancer Institutes
- Hospital and Diagnostic Centers
- Exosomal Proteins as Diagnostic Biomarkers
- Exosome Nucleic Acids as Diagnostics Biomarkers
- Exosomes: Novel Biomarkers for Clinical Diagnosis
- Others: Pharmaceutical and Life Science Industries and Academic Institutes
- Chapter 9 Global Exosome Therapeutic and Diagnostics Market by Region
- North America
- Europe
- Asia-Pacific
- Rest of the World
- Chapter 10 Impact of Exosome Research on Specific Biopharmaceutical Markets
- Biomarker and Diagnostic Industry
- MicroRNA Market
- Liquid Biopsy Market
- Stem Cell Technologies Market
- Prenatal Diagnostic Market
- Agriculture and Food Industry
- Microfluidics and Nanotechnology
- Skincare Industry
- Chapter 11 Patents and Pipeline Analysis
- U.S. Patent Analysis
- European Patent Analysis
- Japanese Patent Analysis
- Pipeline Analysis
- Chapter 12 Market Summary
- Chapter 13 Company Profiles
- CODIAK BIOSCIENCES
- EVOX THERAPEUTICS LTD.
- EXOSOME DIAGNOSTICS INC.
- HANSABIOMED LIFE SCIENCES LTD. (LONZA)
- NANOSOMIX INC.
- SYSTEM BIOSCIENCES (SBI)
- List of Tables
- Summary Table : Global Market for Exosome Diagnostics and Therapeutics, by Application, Through 2026
- Table 1 : Nomenclature of Exosome Particles
- Table 2 : Publication Trend about Exosome, 2010-2020
- Table 3 : Molecules Involved in Exosome Biogenesis and/or Release
- Table 4 : Steps in Exosome Biogenesis and Processing
- Table 5 : Proteins Essential in Exosome Biogenesis and Processing
- Table 6 : Proteins Found in Exosomes
- Table 7 : MicroRNA in Different Bodily Fluids, by Sample
- Table 8 : Methods for Exosome Isolation
- Table 9 : Distribution of Exosomes Isolation Procedures in the Studies Cataloged in ExoCarta
- Table 10 : Data Cataloged in ExoCarta, 2012 and 2017
- Table 11 : Data Cataloged in Vesiclepedia, 2012, 2017 and 2020
- Table 12 : Data Cataloged in EVpedia, 2018
- Table 13 : Comparison of Databases for Exosome Studies
- Table 14 : Coronavirus Reported Cases and Deaths, by Country, as of May 2021
- Table 15 : Examples of Exosomal Proteins for Clinical Diagnostic Applications
- Table 16 : Examples of Exosomal MicroRNA for Clinical Diagnostic Applications
- Table 17 : Characteristic Exosomal MicroRNAs in Various Biological Fluids
- Table 18 : Expression Status of MicroRNAs as the Exosomal Cargo in Different Cancer Types
- Table 19 : Exosomal Protein Biomarkers for Diagnosis of Different Cancers
- Table 20 : Exosomal Nucleic Acid Biomarkers for Diagnosis of Different Cancers
- Table 21 : Statistics for Prostate Cancer, 2021
- Table 22 : Studies of microRNAs in PCa Patients
- Table 23 : Global Market for Prostate Cancer Diagnostics and Related Cost, 2017 and 2022
- Table 24 : Statistics for Breast Cancer, 2021
- Table 25 : Global Market for Breast Cancer Diagnostics, Through 2024
- Table 26 : U.S. Statistics for Bladder Cancer, 2021
- Table 27 : Functions of Exosomal Noncoding RNAs and Proteins in Tumor Metastasis and Invasion
- Table 28 : Global Market for Bladder Cancer Diagnostics, 2017
- Table 29 : Statistics for Ovarian Cancer, 2021
- Table 30 : MicroRNA Content of Ovarian Cancer-Derived Exosomes
- Table 31 : Global Market for Ovarian Cancer Diagnostics, Through 2022
- Table 32 : Summary of the Predictive Exosomal Components Described Until Now, Including Utility and Values Represented, by Sensitivity
- Table 33 : Statistics for Lung Cancer, 2021
- Table 34 : Global Market for Lung Cancer Diagnostics, 2019
- Table 35 : Differences between Liquid and Tissue Biopsy for Cancer Detection and Evaluation
- Table 36 : Global Market for Liquid Biopsy including Research Tools, Services and Diagnostics, Through 2025
- Table 37 : Exosomal Protein Biomarkers from Bodily Fluids of Patients in Pre-Clinical and Clinical Studies
- Table 38 : Exosomal Nucleic Acid Biomarkers in Pre-Clinical and Clinical Studies
- Table 39 : U.S. Statistics for Alzheimer’s Disease, 2021
- Table 40 : Global Market for Alzheimer’s Disease Therapeutics and Diagnostics, Through 2025
- Table 41 : Global Statistics for Hepatitis C Infection, 2020
- Table 42 : Estimated Actual New Cases of HAV (Range), 2016 and 2019
- Table 43 : Global Market for Hepatitis C Diagnostics, 2017
- Table 44 : U.S. Statistics for Cardiovascular Diseases, 2020
- Table 45 : Global Market for Cardiovascular Diagnostics, 2020
- Table 46 : Global Market for Prenatal Diagnostics, Predictive Tests and Neonatal Monitoring, Through 2023
- Table 47 : Global Market for Organ and Tissue Transplantation Products and Devices, Through 2024
- Table 48 : Comparison of Exosome Diagnostics’ Approach to Other Liquid Biopsy Platforms
- Table 49 : Main Market Participants in Exosome-Based Diagnostics Sector
- Table 50 : Global Market for Exosome Diagnostics, Through 2026
- Table 51 : Examples of Studies Using Extracellular Vesicles as Drug Delivery Vehicles
- Table 52 : Examples of Engineering Exosome for Cargo Delivery
- Table 53 : Type of Cargo and Loading Method
- Table 54 : Examples of Physiological Effect of Exosome Delivery
- Table 55 : Global Rankings of Top 10 Vaccine Manufacturers, 2020
- Table 56 : Global Elderly Population with Alzheimer’s Dementia, by Age Group, 2021
- Table 57 : Global Prevalence of Tuberculosis, 2015-2019
- Table 58 : Global Prevalence of Cancer, 2010-2017
- Table 59 : U.S. Statistics for Burn Injuries
- Table 60 : U.S. Statistics for Pressure Ulcers
- Table 61 : Global Market for Aethlon Medical, 2016-2021
- Table 62 : Global Market Revenue, Cost and Profits for Capricor Therapeutics, 2016-2020
- Table 63 : Main Market Participants in Exosome-based Therapeutics Sector
- Table 64 : Examples of Financing for Exosome-based Therapeutics, by Company, Through 2017
- Table 65 : Global Market for Exosome Therapeutics, Through 2026
- Table 66 : Main Steps in Exosome Research Approach
- Table 67 : Examples of Commercial Kits and Reagents for Exosome Isolation
- Table 68 : Frequency of Use for Each Isolation Technique for Exosome Purification
- Table 69 : Range of Model Options with Zetasizer Nano ZS Instrument
- Table 70 : Examples of Detection Assay
- Table 71 : Examples of Antibody Providers for Exosome Research
- Table 72 : Commercial RNA Extraction Kits
- Table 73 : Use of Characterization Techniques for Exosome Samples
- Table 74 : Examples of Purified Exosomes Commercial Products
- Table 75 : Main Market Participants in Exosome Research Tools and Reagents
- Table 76 : Global Market for Exosome Research Tools and Reagents, Through 2026
- Table 77 : Global Market for Exosome Therapeutics and Diagnostics, by End User, Through 2026
- Table 78 : Global Market for Exosomes in Cancer Institutes, by Region, Through 2026
- Table 79 : Studies Employing Exosomes without Genetic Modification in Cancer Treatment
- Table 80 : In Vivo and In Vitro Studies Using Modified Exosomes for Cancer Therapy
- Table 81 : List of Exosomal Bioactive Molecules Involved in Various Progressions
- Table 82 : Global Market for Exosomes in Hospitals and Diagnostics Centers, by Region, Through 2026
- Table 83 : Exosome Proteins in Clinical Diagnostics Applications
- Table 84 : Exosomes: Novel Biomarkers for Clinical Diagnosis
- Table 85 : Global Market for Exosomes in the Others End User Segment, by Region, Through 2026
- Table 86 : Global Market for Exosome Diagnostics and Therapeutics, by Region, Through 2026
- Table 87 : Leading Cause of Deaths Related to Cancer in the UAE, by Cancer Type, 2018
- Table 88 : Leading Causes of Death in Argentina, and Percent Change, 2005-2016
- Table 89 : Examples of Protein Markers in Exosomes and Their Related Pathologies
- Table 90 : Examples of MicroRNA Markers in Exosomes and Their Related Pathologies
- Table 91 : Comparison Between Liquid Biopsy and Tissue Biopsy
- Table 92 : Major Companies Researching and Producing Exosome Products
- Table 93 : U.S. Patents on Exosome Diagnostics and Therapeutics, January 2015–September 2021
- Table 94 : European Patents on Exosome Diagnostics and Therapeutics, January 2015–September 2021
- Table 95 : Japanese Patents on Exosome Diagnostics and Therapeutics, Jan. 2016–Sept. 2021
- Table 96 : Clinical Trials on Various Exosome Molecules
- Table 97 : Global Market for Exosome Diagnostics and Therapeutics, by Application, Through 2026
- Table 98 : Main Participants in the Exosome Market
- Table 99 : Product Portfolio: Codiak Biosciences
- Table 100 : Recent Development: Codiak Biosciences
- Table 101 : Product Portfolio: Evox Therapeutics Ltd.
- Table 102 : Recent Development: Evox Therapeutics Ltd.
- Table 103 : Product Portfolio: Exosome Diagnostics Inc.
- Table 104 : Recent Developments: Exosome Diagnostics Inc.
- Table 105 : Product Portfolio: HansaBioMed Life Sciences Ltd. (Lonza)
- Table 106 : Recent Developments: HansaBioMed Life Sciences Ltd. (Lonza)
- Table 107 : Product Portfolio: Nanosomix Inc.
- Table 108 : Product Portfolio: System Biosciences (SBI)
- List of Figures
- Summary Figure : Global Market for Exosome Diagnostics and Therapeutics, by Application, 2019-2026
- Figure 1 : Publication Trends for Exosomes, 2010-2020
- Figure 2 : Differential Centrifugation Process
- Figure 3 : Ciliated Porous Device Designed to Isolate Exosomes, by Filtration
- Figure 4 : Sieving Models for Exosome Filtration
- Figure 5 : Workflow of MiRNA-Based Therapeutic Delivery Using Exosomes to Treat Alcoholic Liver Disease
- Figure 6 : Global Market for Exosome Diagnostics, 2019-2026
- Figure 7 : Global Prevalence of Cancer, 2010-2017
- Figure 8 : Global Market for Exosome Therapeutics, 2019-2026
- Figure 9 : Global Market for Exosome Research Tools and Reagents, 2019-2026
- Figure 10 : Global Cancer Prevalence, 2005-2016
- Figure 11 : Global Incidence of Patients with Chronic Diseases, 2005-2030
- Figure 12 : U.S. Patent Documents by Published, Filed and Granted Dates, 2015-2021
- Figure 13 : European Patent Documents by Published, Filed and Granted Dates, 2015-2021
- Figure 14 : Japanese Patent Documents by Published, Filed and Granted Dates, 2015-2021
- Figure 15 : Shares of Clinical Trials on Exosomes, by Phase, 2021
- Figure 16 : Global Market for Exosome Diagnostics and Therapeutics, by Application, 2019-2026