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Polymerase Chain Reaction (PCR) In Medical Application - An Analytical Report, 2014-2020 Industry Overview

Polymerase Chain Reaction (PCR) In Medical Application - An Analytical Report, 2014-2020 Industry Overview

III. INDUSTRY OVERVIEW

Life Sciences have different segments with rapid growth and improvement every now and then. Polymerase Chain Reaction (PCR) is a fast moving sector in Life Sciences industry. Molecular Diagnostics and the Human Genome Project (HGP) are two of the main accelerators that contribute to the growth of gene amplification technology. It covers all functions such as Drug Discovery, DNA amplification, Forensic Identification, Gene Therapy and Diagnosis.

Polymerase Chain Reaction is a nucleic acid amplification technology using with very tiny genetic objects which can be enlarged and made copies in just few minutes. It is also used to trace DNA or RNA of pathogenic creatures. Drug discovery and biological research becomes very easy using this technique. This technique is raising curtains from genomic and hereditary diseases by offering pure samples of genetic substance. Academic applications include PCR as a part of their studies while pharma and biotech companies have made it a part of their drug discovery and manufacturing process. It is believed that this technology will be supported by the increasing demand for the molecular diagnosis and human genome applications.

PCR is being used as a primary and alternative technology in various applications. But in spite of its recognition in the industry there are few intricacies involved in disputes. The expiry of the patents has been the major reason in few of the cases. There are many companies which have filed cases against PCR. Applied Biosystems and Roche have been playing the face of all disputes. Promega had prosecuted Applied Biosystems and Hoffman-La Roche.

Roche has started spreading its wings worldwide. It established an R&D center in Shanghai to improve its reach to the wider pharmaceutical and drug markets. It owns the credit of being the first company to set up an R&D division in China. Now PCR technology has become a commonly preferred method of testing and many of its clients and other users have started showing interest in real-time PCR, mainly due to its cost effectiveness, sensitivity and accuracy.

PCR technology has opened new avenues for studies in Human genome and detection of dreaded diseases in human beings. The benefits of the qPCR instruments are attracting more and more users. The major advancement and value-addition to the pattern of drug discovery has added a great impact on the usage of PCR tools. The traditional tools are burdened with the rising prices and demand in the market. The customers look at the price as an initial matter of fact and then come to the quality. All these facts, force the customers to go in for the latest PCR equipments that are user friendly and apt for the diagnostic technologies.

Worldwide Polymerase Chain Reaction market for Products/Tools is estimated to drive US$6.7 billion in 2014 with a CAGR of 10.1% and the market forecasts to reach US$12 billion by 2020.

Nucleic Acid Isolation Markets in Europe, Contract Research Organizations (CROs) Markets in Europe and Advances in Laboratory Automation Markets in Europe are the front runners in research segment of European PCR Reagents Market for Research Applications (a part of the Drug Discovery and Diagnostic Technologies Growth Partnership Service programme).


III. INDUSTRY OVERVIEW
A. INDUSTRY ACTIVITIES
MERGERS/ACQUISITIONS/AGREEMENTS/PATENTS GRANTS/JOINT VENTURES/
INNOVATIONS/PRODUCT LAUNCHES/ETC……
COMPLETE GENOMICS ANNOUNCES UK EPILEPSY SOCIETY’S ACQUISITION OF ITS
REVOLOCITY™ SUPERSEQUENCER
NEW 384-WELL ASSAY FROM AFFYMETRIX DELIVERS HIGH-THROUGHPUT, PCR-FREE GENE EXPRESSION ANALYSIS
AGILENT TECHNOLOGIES TO ACQUIRE SEAHORSE BIOSCIENCE, INDUSTRY LEADER IN TOOLS
FOR MEASURING CELL METABOLISM
COMPREHENSIVE BIOMARKER CENTER NAMED AGILENT TECHNOLOGIES CERTIFIED SERVICE PROVIDER FOR CUSTOM MICRORNA ARRAY SERVICES
ILLUMINA COMPLETES ACQUISITION OF GENOLOGICS
ROCHE TO ACQUIRE KAPA BIOSYSTEMS TO STRENGTHEN NEXT-GENERATION SEQUENCING PRODUCT OFFERINGS
BURNING ROCK AND ILLUMINA COLLABORATE ON MOLECULAR DIAGNOSTICS FOR ONCOLOGY
ROCHE TO ACQUIRE KAPA BIOSYSTEMS TO STRENGTHEN NEXT-GENERATION SEQUENCING PRODUCT OFFERINGS
ROCHE'S PERJETA REGIMEN APPROVED IN EUROPE FOR USE BEFORE SURGERY IN EARLY STAGE AGGRESSIVE BREAST CANCER
WORLD'S FIRST "GO-ANYWHERE" MOLECULAR DIAGNOSTIC SYSTEM UNVEILED AT AACC
QIAGEN COMPANION DIAGNOSTIC WINS FDA APPROVAL FOR USE WITH IRESSA
QIAGEN EXPANDS QIASYMPHONY TEST MENU IN PARTNERSHIP WITH SEEGENE
HITACHI HIGH-TECHNOLOGIES AND QIAGEN ENTER INTO LONG-TERM STRATEGIC COLLABORATION FOR MOLECULAR TESTING
EUROFINS STRENGTHENS ITS FOOTPRINT IN SPECIALTY CLINICAL DIAGNOSTICS WITH
THE ACQUISITION OF DIATHERIX LABORATORIES, INC. IN THE US
PERKINELMER LAUNCHES FIRST FULLY AUTOMATED GENETIC DISORDER SCREENING SYSTEM IN CHINA
ABBOTT'S PIONEERING, INFECTIOUS DISEASE TESTING PLATFORM, IRIDICA, NOW AVAILABLE IN EUROPE
ROCHE RECEIVES FDA EMERGENCY USE AUTHORIZATION FOR THE LIGHTMIX EBOLA ZAIRE RRT-PCR TEST
ROCHE UNVEILS MYCOTOOL REAL-TIME PCR KIT VALIDATION REPORT FOR IMPROVED QUALITY CONTROL OF BIOPHARMACEUTICAL PRODUCTS
ROCHE LAUNCHES PCR MOLECULAR DIAGNOSTIC SYSTEM FOR POINT OF CARE ENVIRONMENT
ROCHE DIAGNOSTICS PURCHASES TISSUE DISSECTION TECHNOLOGY FROM AVANSCI BIO
BECKMAN COULTER DIAGNOSTICS AND SEEGENE ANNOUNCE SUPPLY AGREEMENT FOR MULTIPLEX REAGENTS FOR VERIS MOLECULAR DIAGNOSTICS SYSTEM
AFFYMETRIX LAUNCHES SOLUTION TO ENABLE CANCER RESEARCHERS TO RAPIDLY MAP THE FUNCTIONAL IMPACT OF DNA ALTERATIONS ON GENE EXPRESSION PROFILES TO IDENTIFY POTENTIAL CANCER DRIVER EVENTS
AFFYMETRIX EXCLUSIVELY LICENSES TECHNOLOGY FROM PEPTIDE GROOVE LLP FOR HLA TYPING FROM GENOTYPING DATA
AFFYMETRIX AND ARIOSA DIAGNOSTICS ANNOUNCE SIGNING OF MULTI-YEAR SUPPLY AGREEMENT IN SUPPORT OF ARIOSA’S NON-INVASIVE PRENATAL TEST
BIOFIRE DEFENSE, A BIOMÉRIEUX COMPANY, RECEIVES FAST-TRACK AUTHORIZATION OF FILMARRAY®
EBOLA TEST
HEALTH CANADA APPROVES FIRST NEAR-PATIENT DNA TEST FOR PERSONALIZED MEDICINE
AGILENT TECHNOLOGIES INTRODUCES MIRNA MICROARRAYS FEATURING
LATEST MIRBASE 21 CONTENT
MOBIDIAG ANNOUNCES CE-IVD MARKING OF AMPLIDIAG™ BACTERIAL GE FOR FAST AND ACCURATE PCR-BASED DIAGNOSTICS OF GASTROENTERITIS TEST OPTIMIZES SCREENING OF GASTROENTERITIS-CAUSING BACTERIA DIRECTLY FROM STOOL SAMPLES
NEW ABBOTT TECHNOLOGY MAY UNCOVER THE ROOT OF CRITICAL INFECTIONS AND CUT HEALTH CARE COSTS
AGILENT TECHNOLOGIES INTRODUCES MODULAR REAL-TIME PCR SYSTEM WITH PRECISION OPTICS AND DEPENDABLE THERMAL UNIFORMITY
AGILENT TECHNOLOGIES INTRODUCES NEXT-GENERATION SEQUENCING CANCER RESEARCH PANELS
DAKO LAUNCHES FAST HER2 ISH ASSAY FOR NEW AUTOMATED STAINING PLATFORM IN EUROPE
BIONEER DEVELOPS AN EBOLA VIRUS DETECTION KIT
PERKINELMER LAUNCHES LABCHIP® GX TOUCH AND GXII TOUCHTM AUTOMATED GEL ELECTROPHORESIS SYSTEMS
ALERE RECEIVES FDA CLEARANCE FOR ALERE™ I INFLUENZA A AND B TEST
SALMONELLA SPECIES PCR ASSAY OFFERS VALIDATED METHOD FOR FAST, SIMPLE DETECTION OF FOOD PATHOGENS
BIO-RAD ACQUIRES GNUBIO AND DNA SEQUENCING TECHNOLOGY
OGT TO LAUNCH CANCER SEQUENCING PANEL AT ACGS
OGT EXPANDS GENOMIC MEDICINE PORTFOLIO WITH ACQUISITION OF CYTOCELL
ASPER BIOTECH LAUNCHES MALE FACTOR INFERTILITY TEST
AUTOMATED TRUSEQ® STRANDED TOTAL RNA LIBRARY PREPARATION METHOD FOR EPPENDORF EPMOTION
NOVOGENE ACQUIRES AN ILLUMINA HISEQ X TEN SEQUENCING SYSTEM
BIOMÉRIEUX FINALIZES ACQUISITION OF THE U.S. COMPANY BIOFIRE, SPECIALIZED IN MOLECULAR BIOLOGY
AFFYMETRIX RECEIVES FDA CLEARANCE OF FIRST-OF-ITS-KIND POSTNATAL TEST FOR DEVELOPMENTAL DELAYS AND INTELLECTUAL DISABILITIES IN CHILDREN
EPPENDORF LAUNCHES THE NEW TRANSFERMAN® 4R MICROMANIPULATOR WITH UNPRECEDENTED MOVEMENT CONTROL
TAKARA BIO LAUNCHES NEW RESEARCH REAGENTS RELATING TO THE ADENO-ASSOCIATED VIRUS VECTOR FOR GENE TRANSDUCTION
NEW MICROARRAY FOR IDENTIFYING AND SUBTYPING PATHOGENIC E. COLI USING UNIQUE DNA SIGNATURES
AFFYMETRIX LAUNCHES NEW ONCOSCAN™ FFPE ASSAY KIT
AFFYMETRIX INTRODUCES NEW AXIOM® 384HT GENOTYPING FORMAT ENABLING NEW LEVEL OF COST-EFFECTIVE, HIGH-THROUGHPUT GENOTYPING STUDIES
AFFYMETRIX AND BIODISCOVERY ANNOUNCE SOFTWARE FOR ANALYSIS OF WHOLE GENOME COPY UMBER DATA GENERATED FROM FFPE SOLID TUMOR SAMPLES FOR ACCELERATING CANCER TRANSLATIONAL RESEARCH
COST-EFFECTIVE MULTIPLEX PCR KIT FOR DISTINGUISHING HORSE AND BEEF!
THERMO FISHER SCIENTIFIC TO ACQUIRE LIFE TECHNOLOGIES CORPORATION
VEREDUS LABORATORIES APPROVES THE CURRENT VERSION OF VEREFLU™
BGI-SHENZHEN ACQUIRES COMPLETE GENOMICS INC.
INIBSA GROUP ACQUIRES BIOTECH BIOTOOLS.
AFFYMETRIX AND DNA LINK SIGN PARTNERSHIP FOR PBA PROGRAM FOR HUMAN IDENTIFICATION
MAST UNVEILS NEW ISOTHERMAL NUCLEIC ACID AMPLIFICATION KITS.
FULL SERVICE OF MICROBIAL DIVERSITY PROFILING IS NOW AVAILABLE.
BIOSEARCH TECHNOLOGIES ANNOUNCES ACQUISITION OF DIVISIONS OF DNA TECHNOLOGY AND VITRABIO.
COUNT YOUR DNA WITH DIGITAL PCR AT TATAA BIOCENTER.
MOBIDIAG’S PROVE-IT™ BONE & JOINT, A HIGH-QUALITY MULTIPLEXED MOLECULAR DIAGNOSTIC TECHNOLOGY FOR INFECTIOUS DISEASES, ACHIEVES CE-IVD MARKING
SPOTSTUDIO™‘S EARLY ACCESS PROGRAM STARTED.
FULL PD+ SEQUENCING SERVICE IN TUBE FORMATS IS NOW AVAILABLE.
THERMO FISHER SCIENTIFIC LAUNCHES SURETECT PCR SYSTEM FOR FOOD PATHOGEN DETECTION
CELL SIGNALING TECHNOLOGY RECEIVES PATENT FOR PCR METHODS FOR DETECTION OF A SUBSET OF TREATABLE NON-SMALL CELL LUNG CANCERS
BIO-RAD ACQUIRES ABD SEROTEC
THERMO FISHER SCIENTIFIC SHOWCASES INTEGRATED LAB AUTOMATION PORTFOLIO AT SLAS 2013
ILLUMINA ROLLS OUT SEQUENCING TECHNOLOGY INNOVATIONS
TATAA BIOCENTER INTRODUCES QPCR WORKFLOW
B. MARKET TRENDS
SPARTAN BIOSCIENCE DX-12™ DNA ANALYZER – A BOON TO BIOTECHNOLOGY
REDDYMIX - A BUFFER FOR PCR REAGENTS
NEXT GENERATION PCR APPROVES EVOLUTION POLYMERASES
QUICKPROBE(TM) QPCR- A BONUS TO LIFE SCIENCES COMPANIES
MASTER CLEAR CAP STRIPS® - AN ADDITION TO PCR CONSUMABLES
DIGITAL PCR TECHNOLOGY BY FLUIDIGM
GREENECHIP TECHNOLOGY- UNPREJUDICED PATHOGEN DISCOVERY
INCREASING DEMAND FOR QRT-PCR PRODUCTS
QIAGEN’S NEW SOLUTION TO ACCELERATE PCR
OPTO TECHNOLOGY’S NEW INVENTION - OTHP-0050
TIE UP BETWEEN FISHER BIOSCIENCES AND APPLIED BIOSYSTEMS
FISHER BIOSCIENCES AND DYOMICS MERGE FOR BETTERMENT
PCR MACHINES - IMPACT ON LIFE SCIENCES EQUIPMENT
A HOME-BREW REAL-TIME PCR ASSAY FOR CONSISTENT RECOGNITION AND MEASUREMENT OF MATURE MIR-122
RELEVANCE OF THE POLYMERASE CHAIN REACTION TO QUICK EXAMINATION OF BREWERY YEAST STRAINS
AMPLIFICATION INVENTORY: DPCR OR QPCR?
DESCRIPTION OF QPCR AND DPCR
THE GOLD STANDARD
WHAT NEEDS TO BE ACCOMPLISHED?
C. INDUSTRY LEADERS
ABBOTT LABORATORIES (USA)
AGILENT TECHNOLOGIES INC (USA)
BIONEER INC (USA)
COMPLETE GENOMICS, INC. (USA)
EPICENTRE® BIOTECHNOLOGIES (USA)
GENISPHERE INC. (USA)
MAXIM BIOTECH, INC (USA)
OCIMUM BIOSOLUTIONS LTD.
QIAGEN INC (USA)
SACACE BIOTECHNOLOGIES S.R.L. (ITALY)
TAKARA BIO, INC.
THERMO FISHER SCIENTIFIC, INC.
LIGHTUP TECHNOLOGIES AB (SWEDEN)
HY LABORATORIES LTD. (ISRAEL)
369. WORLDWIDE KEY PLAYERS INTO POLYMERASE CHAIN REACTION (PCR) INDUSTRY THAT
PROJECT IMPROVED MARKET ACTIVITIES IN THE NEAR FUTURE
D. POLYMERASE CHAIN REACTION (PCR) IN MEDICAL APPLICATION – A LOOK A HEAD..!!
E. KEY COMPANY PROFILES
NORTH AMERICA
ABBOTT LABORATORIES
AFFYMETRIX, INC.
AGILENT TECHNOLOGIES, INC.
BD BIOSCIENCES
BECKMAN COULTER, INC.
BIONEER, INC.
BIO-RAD LABORATORIES, INC.
CEPHEID
COMBIMATRIX CORPORATION
COMMONWEALTH BIOTECHNOLOGIES, INC
COMPLETE GENOMICS, INC.
ENZO BIOCHEM
EPICENTRE® BIOTECHNOLOGIES
GE HEALTHCARE (LIFE SCIENCES)
GENISPHERE INC.
ILLUMINA
LI-COR BIOSCIENCES
LUCIGEN CORPORATION
MAXIM BIOTECH, INC
PROMEGA CORPORATION
QIAGEN, INC.
SEQUETECH CORPORATION
DNA LANDMARKS, INC.
ROCHE DIAGNOSTICS (A DIVISION OF F.HOFFMANN-LA ROCHE LIMITED)
SPARTAN BIOSCIENCE INC
THERMO FISHER SCIENTIFIC, INC.
GENSCRIPT USA INC.
OXFORD GENE TECHNOLOGY (OGT)
SHIMADZU BIOTECH
SACACE BIOTECHNOLOGIES S.R.L.
DNAVISION SA
EXIQON
BIOTAGE AB
MICROSYNTH AG
ASIA-PACIFIC
HOKKAIDO SYSTEM SCIENCE CO., LTD.
OCIMUM BIOSOLUTIONS LTD.
AGRIGEN BIOTECH PTY LTD.
GENEWORKS PTY LTD
TAKARA BIO, INC.
REST OF WORLD
INQABA BIOTECHNICAL INDUSTRIES (PTY) LTD.
F. POLYMERASE CHAIN REACTION (PCR) – PATENTS
PCR PATENT EXPIRY AND ITS EFFECT ON MARKET STRATEGIES
EXPIRY OF PCR PATENT OFFERS EXCITING GROWTH OPPORTUNITIES FOR NUCLEIC
ACID PURIFICATION AND AMPLIFICATION TECHNOLOGIES
INNOVATIVE FEATURES WIDEN APPLICATION BASE AND BOOST REVENUE
PATENT EXPIRATION
MOLECULAR DIAGNOSTICS UNCHAINED
THE POLYMERASE CHAIN REACTION PATENT ENDING: AN EXPIRING PATENT MARKS THE END OF A BIOTECHNOLOGICAL ERA
EXPIRING PATENTS, UPTICK IN BIOTECH SPENDING COULD SPUR QPCR-BASED DX, TOOL DEVELOPMENT
THE POLYMERASE CHAIN REACTION PATENTS: GOING, GOING,
THE POST-PATENT OPPORTUNITY
PATENT WARS
PCR - A PATENT THAT REVOLUTIONIZED BIOTECHNOLOGY AND LAUNCHED A TV SERIES
PATENT RULING COULD CUT PCR ENZYME PRICES
PCR PATENT ISSUES
1. INTRODUCTION
2. INTELLECTUAL PROPERTY RIGHTS
3. NAVIGATING THE PCR PATENT MINEFIELD
3.1. OBTAINING RIGHTS TO PRACTICE PCR
3.2. BONA-FIDE RESEARCHERS ARE NOT INFRINGERS
3.3. NOT EVERY PATENT IS A VALID PATENT
370. THE PATENTS OF DIFFERENT COMPANIES ACROSS GLOBE WITH THEIR TITLE, FILLING AND ISSUE DATES, ABSTRACT
371. THE PATENTS ACROSS GLOBE WITH THEIR FILLING & PUBLICATION DATES AND ABSTRACT (2014-2015)
IV. INDUSTRY COMPANY DATABASE
V. APPENDIX
A. RESEARCH FOCUS
B. ABOUT AXIS RESEARCH MIND
D. FEEDBACK

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