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Tuberculosis: The Global Cost of Diagnosis 2000

Published by: The Apex Group

Published: Oct. 1, 2000 - 55 Pages


Table of Contents


1. Introduction

2. The Context: Estimates for the Overall Diagnostics Market

Table 1. Worldwide In Vitro Diagnostics Sales Per Capita - 1996-2002

2.1 Diagnostic Testing

Table 2. Proportionate Market Share of the Main IVD Companies - 1998

Table 3. Worldwide In Vitro Diagnostics - Sales by Country - 1996-2002

Table 4. Global Medical Technology Market by Product Grouping - 1996

2.2 Infectious Disease as a proportion of the total

Table 5. Worldwide In Vitro Diagnostics - Sales by Product Type - 1996-2002

Table 6. Worldwide Nucleic Acid Assay Sales by Test Category - 1996-2002

Table 7. Rapid Microbiology Test and Instrument Market - W. Europe - 1990-2000

2.3 Main Market Trends

3. Diagnosing Tuberculosis in Humans

Figure 1. Reported TB Cases by World Region (% of Total) - 1997

3.1 Population

3.2 Estimated number of cases of TB

3.3 Regional variations

3.3.1 Developed World (Population 790 million)

3.3.2 Middle Developed World (Population 3 billion)

3.3.4 Under-developed World (Population over 2 billion)

Table 8. Existing Market for Diagnosis of TB and Potential Additional Market for the Diagnosis of TB (if all WHO estimated cases are tested)

4. Diagnosing Paratuberculosis in Cattle, Sheep and Goats

Table 9. Proportional breakdown of highest level of diagnosis by source

4.1 Explanation of Basis for Assumptions and Variables

4.1.1 Region

4.1.2 Proportion of species in affected operations

4.1.3 Proportion of cases in which diagnosis by testing is likely to be used

4.1.4 Cost of Tuberculin Testing per Animal

Table 10. Herd and Total Cattle Tests in Great Britain since 1995

Table 11. Costs Breakdown of Bovine TB Control Programme in Great Britain - 1996-97

4.1.5 Total cost of all animals likely to be properly 'tested'

4.1.6 Cost of testing all animals in affected operations

Table 12. Current and Potential Market estimates for testing of Sheep Cattle and Goats for Paratuberculosis 1998

5. Diagnosing M. bovis in Cattle

Figure 2. Bovine Tuberculosis Occurrence, Africa.

Figure 3. Control measures for Bovine Tuberculosis based on test-and-slaughter policy and disease notification, Africa.

Figure 4. Bovine Tuberculosis Occurrence, Asia

Figure 5. Control measures for Bovine Tuberculosis based on test-and-slaughter policy and disease notification, Asia

Figure 6. Bovine Tuberculosis Occurrence, Latin America and the Caribbean

Figure 7. Control measures for Bovine Tuberculosis based on test-and-slaughter policy and disease notification, Latin America and the Caribbean

Table 13. Cattle Numbers - World - 1998

5.1 Estimated Value of Testing for Mycobacterium Bovis in Cattle

Table 14. Herd and Total Cattle Tests in Great Britain since 1995

5.1.1 Proportion of Animals Tested

5.1.2 Proportion of cases in which Laboratory Diagnosis is likely

5.1.3 Cost of testing

Table 15. Diagnosis of Bovine TB, 1998

6. Other TB Testing related markets

Figure 8. M. avium Subtypes

6.1 Avian Tuberculosis - Summary

6.2 HIV and Tuberculosis

Table 16. Estimated human tuberculosis and HIV-attributable tuberculosis cases in 1990, 1995 and 2000, by region

6.3 Extension of testing application

6.4 Summary of Diagnostic Techniques

6.4.1 RFLP

6.4.2 PCR

6.4.3 DNA Probes

6.4.4 Immunohistochemistry

6.4.5 Immunoblotting

6.4.6 Antigen-capture enzyme-linked immunosorbent assay

6.4.7 Antibody Detection

7. Conclusions

Table 17. Market Estimate - 1999

Table 18. Existing versus potential Market

8. Future prospects:

Table 19. Increasing incidence of TB

Table 20. Forecast estimates for the TB testing market 1998-2002

9. Glossary

10. Sources

10.1 Publications:

10.2 Organisations:

11. For More Information


Abstract

The World Health Organisation (WHO) describes TB as their biggest killer disease of humans globally. However the use of techniques used to identify the pathogen causing the illness are all subject to the "speed versus accuracy versus cost" ratio balance. In recent years there have been many advances in the use of biotechnology as a means of identifying clinical conditions. The development of this market will have a tremendous effect on the cost of tuberculosis identification necessary for better disease control. As a measure of the rate of development, the first section of this report will focus on the diagnostics market as a whole.

This reports sets out to identify the size and value of the rapid test kit market for Tuberculosis strains:

  • M. tuberculosis
  • M. avium ss paratuberculosis
  • M. bovis


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