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MEK Inhibitor Market Size, Share, By Target [MEK1, and MEK2], Type (MEKINIST, COTELLIC, MEKTOVI, and Others), Application (Non-small Cell Lung Cancer, Metastatic Melanoma, KRAS & NRAS Mutated Tumors, Thyroid Carcinoma, Lung Carcinoma, and Others), Distrib

Published Aug 01, 2023
Length 168 Pages
SKU # PRMI20123697

Description

MEK Inhibitor Market Size, Share, By Target [MEK1, and MEK2], Type (MEKINIST, COTELLIC, MEKTOVI, and Others), Application (Non-small Cell Lung Cancer, Metastatic Melanoma, KRAS & NRAS Mutated Tumors, Thyroid Carcinoma, Lung Carcinoma, and Others), Distribution Channel (Hospital Pharmacy, Retail Pharmacy, and Online Pharmacy) and Region - Trends, Analysis, and Forecast till 2035

The MEK Inhibitor Market Report offers an in-depth exploration of emerging market trends, driving factors, challenges, and key segments that shape the industry. It includes a thorough examination of regulatory frameworks, company profiles, and the latest industry developments. The report delves into product development, positioning strategies, and the impact of new technologies on the market landscape. By identifying challenges and opportunities, the report provides a detailed roadmap for market growth.

MEK inhibitor market is a type of drug that specifically targets and inhibits the MEK enzymes, which is crucial for MAPK signaling pathway. MEK inhibitors are used in the treatment of cancer, by blocking MEK activity, which prevent the growth of cancer cells. These drugs are commonly used in the treatment of certain cancers, such as melanoma, non-small cell lung cancer (NSCLC), and colorectal cancer, especially where there are mutations in the BRAF gene. MEK inhibitors are often used in combination with other targeted therapies, such as BRAF inhibitors, to improve treatment efficacy and delay the development of resistance, is responsible to growth of MRK inhibitor market share.

Report Highlights:

The market size is accounted for USD 6.8 Billion in 2025.

The MEK inhibitor market size is estimated to grow at a rate of USD 14.9 Billion by 2035, and developing at a CAGR of 9.0%.

Based on target, MEK 1 is the leading segment in MEK inhibitor market.

By type, MEKINIST is prevailing segment in MEK inhibitor market.

Under application, non-small cell lung cancer is anticipated as dominating segment in MEK inhibitor market.

Hospitals pharmacy segment dominated in MEK inhibitor by distribution channel way.

The MEK Inhibitor market is dominated by North America region.

Asia Pacific is projected as highest growing segment in market.

Key Highlights

In February 2021, Merck KGaA, got approval for two oral MEK inhibitors to Day One Biopharmaceuticals. This collaboration was aimed to allow Day One to test pimasertib in combination with its pan-RAF kinase inhibitor, to expand its potential application in solid tumors. Merck initiated a series of studies to assess the molecule as both a single agent and in combination therapy in multiple cancers. Merck took another MEK1/2 inhibitor, MSC2015103B, into the clinic to target this pathway for therapeutic benefit.

Report Analysis:

Reactivation of MAPK Pathway:

Mitogen-activated protein kinase (MAPK) pathway inhibitors, such as MEK inhibitors, are utilized in cancer therapy to suppress tumor growth by targeting key components of the MAPK signaling cascade. Mutations in upstream kinases such as RAF and RAS can reactivate the MAPK pathway despite MEKi treatment, contributing to resistance. MEKi can lead to the upregulation of RTKs such as EGFR, ERBB3, IGF-1R, and PDGFR. This reactivation occurs due to ERK1/2, characteristically repressed by MEK, is suppressed during MEKi treatment, leading to the disinhibition of these RTKs. The reactivated RTKs can initiate alternative signaling pathways that promote cell survival and proliferation, thereby contributing to adaptive resistance.

Segmentation:

By Target:
  • MEK1
  • MEK2
By Type:
  • MEKINIST
  • COTELLIC
  • MEKTOVI
  • Others
By Application:
  • Non-small Cell Lung Cancer
  • Metastatic Melanoma
  • KRAS and NRAS Mutated Tumors
  • Thyroid Carcinoma
  • Lung Carcinoma
  • Others
By Distribution Chanel:
  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy
By Region:
  • North America
o U.S.

Canada
  • Europe
o Germany

U.K.

France

Russia

Italy

Spain

Netherlands

Rest of Europe
  • Asia Pacific
o China

India

Japan

Australia

Indonesia

Malaysia

South Korea

Rest of Asia Pacific
  • Latin America
o Brazil

Mexico

Argentina

Rest of Latin America
  • Middle East & Africa
o GCC

Israel

South Africa

Rest of Middle East & Africa

The report also includes a competitive analysis with a detailed SWOT review, examining the strengths, weaknesses, opportunities, and threats of each leading company, as well as their market share and product offerings

MEK Inhibitor Market Companies:

Pfizer Inc.

Novartis AG

Bayer AG

Merck & Co., Inc.

ONO PHARMACEUTICAL CO., LTD.

Atriva Therapeutics

GSK plc.

SpringWorks Therapeutics, Inc.

Genentech, Inc.

MedChemExpress

NFlection Therapeutics Inc.

CSTONE PHARMACEUTICALS

What Our Report Delivers:
  • Regional & Country-Level Market Insights: Detailed market share analysis across key regions and countries to help you understand competitive positioning.
  • Guidance for New Market Players: Actionable strategic recommendations for businesses entering the market, ensuring a strong foothold from the start.
  • Comprehensive Market Forecasts: Reliable data projections for 2024, 2025, 2026, 2028, and 2032 to support long-term planning and investment decisions.
  • In-Depth Market Dynamics: Analysis of drivers, restraints, opportunities, and emerging threats, along with challenges and high-potential investment areas.
  • Data-Driven Business Strategies: Expert recommendations tailored to key market segments, backed by precise market evaluations.
  • Competitive Intelligence: Mapping of prevailing industry trends and competitor strategies to identify growth opportunities.
  • Detailed Company Profiles: In-depth analysis of major players, including their business strategies, financial performance, and recent developments.
  • Supply Chain Innovations: Insights into the latest technological advancements and trends shaping supply chain efficiency.
FAQs:

Key Questions Answered in the Report.

What was the MEK Inhibitor Market size in 2025?

What is projected growth rate of the MEK Inhibitor Market during 2025-2035?

What are the key factors driving the MEK Inhibitor Market growth?

What are leading players in the MEK Inhibitor Market ?

What are the key regions analyzed in the MEK Inhibitor Market ?

Which region is dominating in the MEK Inhibitor Market ?

Table of Contents

168 Pages
MEK Inhibitor Table of Contents
Research Objective and Assumption
Research Objectives
Assumptions
Abbreviations
Market Preview
Report Description
Market Definition and Scope
Executive Summary
Market Snippet, By Target
Market Snippet, By Type
Market Snippet, By Application
Market Snippet, By Distribution Chanel
Market Snippet, By Region
Opportunity Map Analysis
Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Drivers
Restraints
Market Opportunities
Market Trends
Type Launch
Merger and Acquisitions
Impact Analysis
PEST Analysis
Porter’s Analysis
Ras/Raf/MEK/ERK Pathway
Chemical formula of trametinib
MEK Inhibitors under Clinical Development
Market Segmentation, By Target, Forecast Period up to 10 Years, (USD Bn)
Overview
Market Value and Forecast (USD Bn), and Share Analysis (%), Forecast Period up to 10 Years
Y-o-Y Growth Analysis (%), Forecast Period up to 10 Years
Segment Trends
MEK1
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
MEK2
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Market Segmentation, By Type, Forecast Period up to 10 Years, (USD Bn)
Overview
Market Value and Forecast (USD Bn), and Share Analysis (%), Forecast Period up to 10 Years
Y-o-Y Growth Analysis (%), Forecast Period up to 10 Years
Segment Trends
MEKINIST
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
COTELLIC
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
MEKTOVI
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Others
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Market Segmentation, By Application, Forecast Period up to 10 Years, (USD Bn)
Overview
Market Value and Forecast (USD Bn), and Share Analysis (%), Forecast Period up to 10 Years
Y-o-Y Growth Analysis (%), Forecast Period up to 10 Years
Segment Trends
Non-small Cell Lung Cancer
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Metastatic Melanoma
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
KRAS and NRAS Mutated Tumors
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Thyroid Carcinoma
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Lung Carcinoma
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Others
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Market Segmentation, By Distribution Channel, Forecast Period up to 10 Years, (USD Bn)
Overview
Market Value and Forecast (USD Bn), and Share Analysis (%), Forecast Period up to 10 Years
Y-o-Y Growth Analysis (%), Forecast Period up to 10 Years
Segment Trends
Hospital Pharmacy
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Retail Pharmacy
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Online Pharmacy
Overview
Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
Market Segmentation, By Region, Forecast Period up to 10 Years, (USD Bn)
Overview
Market Value and Forecast (USD Bn), and Share Analysis (%), Forecast Period up to 10 Years
Y-o-Y Growth Analysis (%), Forecast Period up to 10 Years
Regional Trends
North America
Market Size and Forecast (USD Bn), By Target, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Type, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Distribution Channel, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
U.S
Canada
Asia Pacific
Market Size and Forecast (USD Bn), By Target, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Type, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Distribution Channel, Forecast Period up to 10
Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
China
India
Japan
Australia
Indonesia
Malaysia
South Korea
Rest of Asia Pacific
Europe
Market Size and Forecast (USD Bn), By Target, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Type, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Distribution Channel, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
Germany
U.K.
France
Russia
Italy
Spain
Netherlands
Rest of Europe
Latin America
Market Size and Forecast (USD Bn), By Target, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Type, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Distribution Channel, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
Brazil
Mexico
Argentina
Rest of Latin America
Middle East and Africa
Market Size and Forecast (USD Bn), By Target, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Type, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Distribution Channel, Forecast Period up to 10 Years
Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
GCC
Israel
South Africa
Rest of Middle East and Africa
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