U.S. Microfluidics Market Size, Share & Trends Analysis Report By Product (Microfluidic-based Devices, Microfluidic Components), By Material Type (Silicon, Glass), By Technology, By Application) - Industry Analysis, Size, Share, Growth, Trends, and Foreca

U.S. Microfluidics Market Size and Growth
The U.S. microfluidics market size was estimated at USD 13.11 billion in 2023 and is expected to be worth around USD 39.29 billion by 2033, poised to grow at a compound annual growth rate (CAGR) of 11.6% during the forecast period 2024 to 2033.

U.S. Microfluidics Market Key Takeaways

Polydimethylsiloxane (PDMS) dominated the market and held the highest revenue market share of 35.89% in 2023 and is expected to grow at the fastest CAGR during the forecast period.
Glass has the second-highest market revenue share in 2023 and is expected to witness lucrative growth during the forecast period.
Microfluidic components dominated the market with the largest revenue share of 70.14% during 2023 and are expected to grow at the highest CAGR during the forecast period.
Microfluidic-based devices are anticipated to grow quickly during the forecast period.
Lab-on-a-chip dominated the market with the highest CAGR of 37.11% in 2023.
Organs-on-chips is anticipated to witness the fastest growth of CAGR of 14.7% from 2024 to 2033.
Medical dominated the market and held the highest revenue share of 81.69% in 2023 and is expected to grow at the fastest CAGR during the forecast period.
Non-medical segment is expected to grow lucratively during the forecast period.

U.S. Microfluidics Market Growth
The demand for microfluidics devices is driven by their capacity to conserve rare samples and reduce reagent waste by analyzing small sample amounts. Cutting-edge technologies have been developed as a result of their growing application in research and diagnostics. The market has grown as a result of the expansion of applications for microfluidics-based lab equipment in pharmaceutical and biomedical research, as well as their compatibility with current research processes.
In 2023, the U.S. held a market share of about 39.2% in the global microfluidics industry. The market is expected to increase as a result of the increasing use of microfluidics devices in various research and diagnostic applications. For instance, there have been more microfluidic devices that are appropriate for treating eye-related disorders in the last ten years. The increase of uses of microfluidics technology in biomedical and pharmaceutical research has been largely attributed to the development of microfluidics-based lab equipment into more robust instruments that are compatible with established research procedures. It is anticipated that microfluidics will be employed in biological settings. Micro-scale procedures are carried out by experts in this field to guarantee better control, quicker outcomes, and reduced expenses at different phases of drug development.
The number of COVID-19 cases has surged, which has raised the need for microfluidics instruments. Widely accepted, PCR-based diagnostics are now the standard for COVID-19 diagnosis. Many manufacturers have boosted production and introduced new products in response to the pandemic in order to accommodate the growing demand for IVD tests. By combining microfluidics with PCR, testing can be accelerated and results can be obtained with high precision in less than ten minutes. For example, BeforCure, a spin-off of Elvesys, has created a quick PCR-on-chip virus detection method. This product, which is based on Fastgen technology, uses the advantages of microfluidics to deliver test results in less than 30 minutes.
The ability of microfluidics devices to evaluate small sample volumes is a major advantage. This helps preserve difficult-to-produce samples and reduces reagent waste. The need for low-volume sample devices has increased with the release of these devices. This need has been further spurred by a rise in research efforts by clinical and analytical researchers. Conventional genome analysis techniques are expensive and time-consuming since they require decoding the complete DNA. Because they can analyze small sample volumes, microfluidics devices have advantages like less waste from reagents and sample conservation. Since their introduction, the need for low-volume sample analysis has grown, as has their application in research.
Compared to conventional genome analysis techniques, these devices are more efficient since they require smaller sample volumes for data interpretation. They made it possible to reduce lab processes and replace them with lab-on-a-chip technologies. Recent product introductions, such as the low-volume online degassing modules from Biotech Fluidics that were introduced in July 2023, have boosted the market.
Microfluidics devices for ophthalmological diseases have grown increasingly accessible over the last ten years. They have effectively assessed vascular endothelium growth factor levels, detected infections, and measured glucose levels. Contact lens technology has been exploited in recent years to provide diagnostic and therapeutic options. Guan's group, for example, created a contact lens-on-a-chip for precision medical care. Among these developments is the analysis of small-volume nasal secretions for illness research.
A group from Loschmidt laboratories developed a microfluidic platform for efficient and rapid enzyme research in March 2021 in association with ETH Zurich. This cutting-edge technology is already being used to study the evolution of bioluminescent enzymes and create novel thrombolytics for the treatment of stroke. Additionally, in November 2019, IMT and Panasonic Corporation collaborated to create a glass molding technology for mass-producing microfluidic devices. Devices for biological, environmental, and medical analysis and sensing are made using this approach, which is more accurate and economical than conventional glass etching methods. It is anticipated that this will help the industry expand in the future.
U.S. Microfluidics Market Report Scope

Report Attribute
Details

Market Size in 2024
USD 14.63 Billion

Market Size by 2033
USD 39.29 Billion

Growth Rate From 2024 to 2033
CAGR of 11.6%

Base Year
2023

Forecast Period
2024 to 2033

Segments Covered
Product, application, material type, technology

Market Analysis (Terms Used)
Value (US$ Million/Billion) or (Volume/Units)

Report Coverage
Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Key Companies Profiled
Illumina, Inc.; F. Hoffmann-La Roche Ltd; PerkinElmer, Inc.; Agilent Technologies, Inc.; Bio-Rad Laboratories, Inc.; Danaher Corporation; Abbott; Thermo Fisher Scientific; Standard BioTools

U.S. Microfluidics Market Trends

Increasing Adoption in Healthcare: Microfluidics technology is being increasingly adopted in the healthcare sector for various applications such as point-of-care diagnostics, drug delivery systems, and personalized medicine. The ability of microfluidic devices to manipulate small amounts of fluids with high precision makes them valuable in developing diagnostic tools and improving drug delivery methods.
Point-of-Care Diagnostics: There's a growing demand for point-of-care diagnostics due to the need for rapid and accurate testing, especially in remote or resource-limited settings. Microfluidic devices offer portable and cost-effective solutions for diagnosing diseases such as infectious diseases, cancer, and metabolic disorders.
Miniaturization and Integration: Microfluidic systems are becoming more miniaturized and integrated, allowing for the development of lab-on-a-chip devices. These devices can perform multiple laboratory functions on a single chip, reducing the need for large and expensive laboratory equipment. This trend is driving innovation in areas such as sample preparation, analysis, and detection.
Biomedical Research: Microfluidics is playing a crucial role in advancing biomedical research by enabling researchers to study cellular behavior, perform high-throughput screening, and conduct experiments with small sample volumes. The technology offers precise control over experimental conditions, leading to more reproducible results and accelerating the pace of scientific discovery.
Emerging Applications: The microfluidics market is expanding into new and emerging applications beyond healthcare, including environmental monitoring, food safety testing, and industrial processes. These applications leverage the unique capabilities of microfluidic devices to analyze complex samples, detect contaminants, and monitor processes in real-time.
Investment and Collaboration: There is a growing investment in microfluidics startups and research initiatives by both public and private sectors. Collaborations between academic institutions, industry players, and government agencies are driving innovation and technology transfer in the field.
Regulatory Challenges: Despite the rapid growth and potential of microfluidics technology, there are regulatory challenges related to standardization, validation, and approval of microfluidic devices for clinical and commercial use. Addressing these challenges is crucial for ensuring the safety, efficacy, and widespread adoption of microfluidic-based products.

U.S. Microfluidics Market By Material Type Insights
Polydimethylsiloxane (PDMS) dominated the market and held the highest revenue market share of 35.89% in 2023 and is expected to grow at the fastest CAGR during the forecast period. PDMS, a polymer extensively used in microfluidics, offers numerous benefits such as non-toxicity, durability, optical clarity, gas and oxygen permeability, biocompatibility, elasticity, affordability, and the ability to create intricate microfluidic device designs by layering multiple levels. The swift uptake of microfluidics-enabled LOC devices has opened numerous growth avenues for PDMS in experimental microfluidics. Given its biocompatibility, permeability, and minimal autofluorescence, PDMS is projected to see substantial use in various future biotechnology and biomedical engineering applications.

Glass has the second-highest market revenue share in 2023 and is expected to witness lucrative growth during the forecast period. Glass is a preferred material in microfluidics due to its optical transparency, chemical inertness, and biocompatibility, making it suitable for various applications in the field. In addition, Glass offers excellent properties for microfluidic devices, such as low autofluorescence levels and high thermal stability, which are crucial for maintaining the integrity of samples and ensuring accurate results in microfluidic systems. These characteristics make Glass a popular choice in the microfluidics industry, contributing to its significant market revenue share.
U.S. Microfluidics Market By Product Insights
Microfluidic components dominated the market with the largest revenue share of 70.14% during 2023 and are expected to grow at the highest CAGR during the forecast period. Based on microfluidic components, the market is segmented into chips, micro-pumps, sensors, and other components used in microfluidic devices. These components are small and offer flexibility in applications. These components support numerous instruments and technological applications, such as automation, screening, analysis, and quantitative determination of biological elements like galactose. The market demand for microfluidic components is predicted to rise in response to the increasing need for analyzing low-volume samples and the ongoing development of advanced technologies in this field. Droplet microfluidics, for example, has emerged as a powerful tool that enables fast and cost-effective compartmentalization of cells and analytes under precisely controlled conditions. This technology is highly robust and can facilitate high-throughput screening, further driving growth in the market during the projected period.
Microfluidic-based devices are anticipated to grow quickly during the forecast period. These devices leverage the principles of microfluidics to analyze fluids at the microscale level. They offer various advantages for biological analysis. Devices based on microfluidics require low reagent volume and smaller samples. These items are generally difficult to isolate when used in bulk quantities and are expensive. Hence, microfluidic-based devices reduce the significant cost of the entire laboratory analytical process. In addition, these devices are smaller, which saves space and allows the simultaneous processing of multiple analytes. Such benefits associated with these systems are expected to drive the microfluidic-based devices market.
U.S. Microfluidics Market By Technology Insights
Lab-on-a-chip dominated the market with the highest CAGR of 37.11% in 2023. This technology enables quick DNA probe sequencing and high-speed thermal shifts at the microscale for DNA amplification using PCR. Elveflow’s Fastgene system, the fastest qPCR system, can detect bacteria and viruses in just 7 minutes. Nanopore technologies promise faster genome sequencing of DNA probes than traditional lab-on-a-chip methods. They also offer the potential for quick immunoassays, which can be done in 10 seconds, significantly faster than macroscopic technologies. Lab-on-a-chip technology has shown potential in cell biology, particularly in regulating cells at the single-cell level while handling large volumes of cells quickly. Elveflow’s Opto Reader, a fast-optical detector, aids cell detection and isolation. The technology is also used in stem cell differentiation, micro patch-clamp, cell sorting, and high-speed flow cytometry. Thus, lab-on-a-chip technology holds great promise for ultra-fast detection of viruses and bacteria.
Organs-on-chips is anticipated to witness the fastest growth of CAGR of 14.7% from 2024 to 2033. They play a crucial role in the discovery and development of drugs. The National Center for Advancing Translational Science (NCATS), in collaboration with the FDA and other National Institute of Health (NIH) centers, has focused on drug discovery since 2012 through its Tissue Chip for Drug Screening initiative. This initiative involves creating human tissue chips that accurately represent human organs, aiming to bridge the gap between research discovery and clinical trials and focus on high-need cures. For example, in March 2022, NCATS collaborated with the U.S. The FDA and various NIH institutes are collaborating to create human tissue chips that closely resemble the structure and function of organs in the human body, including the heart, liver, and lungs. This effort aims to enhance the accuracy and speed of predicting human drug safety.
U.S. Microfluidics Market By Application Insights
Medical dominated the market and held the highest revenue share of 81.69% in 2023 and is expected to grow at the fastest CAGR during the forecast period. Microfluidics, a key technology in biological analysis, chemical synthesis, and IT, has revolutionized conventional lab equipment. It allows minimal reagent use, maximum information from small samples, simplified assay protocols, improved sample processing, and precise control of cell microenvironments. Its benefits extend to medical and pharmaceutical applications, including infectious disease diagnosis, cancer treatment, and the creation of functional tissues and organs. For instance, in August 2022, a team in Atlanta developed the Cluster-Well chip using microfluidics to detect and treat metastatic cancer swiftly. In addition, the ability to automate the preparation of PCR reaction mix is a feature of microfluidic PCR devices. This automation significantly reduces the chances of false positives and contamination due to human error.
Non-medical segment is expected to grow lucratively during the forecast period. Microfluidics is used for crude oil extraction, plant pathogen detection, and gas bubble production in non-medical fields. It’s ideal for developing methods to extract crude oil from pollutant-mixed porous rocks due to its ability to handle complex interactions between pore structure and fluids. Gas bubbles, particularly micron-scale ones, are widely used in various industries, including food for fat reduction, texture tailoring, and other industries for producing active ingredients, mesoporous materials, and natural gas recovery. Generating micron-scale gas bubbles in the microfluidic industry offers new opportunities for highly controlled fluid compartmentalization.
U.S. Microfluidics Market Recent Developments

In March 2024, Bio-Rad Laboratories received approval from AOAC International for its dd-Check STEC Solution. This solution, the first of its kind to use the Droplet Digital PCR Method, is designed to detect and confirm the presence of virulence genes from Shiga toxin-producing Escherichia coli (STEC) in raw beef trim, fresh spinach, and carcass sampling cloths. The approval indicates that the dd-Check STEC Solution is aligned with the standard reference method for confirming STEC.
In January 2024, Standard BioTools Inc. (Nasdaq: LAB), a company committed to propelling advancements in human health, declared the completion of its merger with SomaLogic. This merger has resulted in forming a leading entity in the field of research, providing unique multi-omics tools.
In March 2023, PerkinElmer Inc. announced the successful completion of the divestiture of its Applied, Food, and Enterprise Services businesses. New Mountain Capital, a firm focused on growth-oriented investments, acquired these businesses.
In August 2022, Thermo Fisher Scientific, a global pioneer in scientific services, unveiled its Applied Biosystems HIV-1 Genotyping Kit with Integrase. This kit, intended solely for research purposes, scrutinizes samples testing positive for the human immunodeficiency virus (HIV). Its primary function is to detect genetic variations that exhibit resistance to standard antiretroviral treatments.

U.S. Microfluidics Market Top Key Companies:

Illumina, Inc.
F. Hoffmann-La Roche Ltd.
PerkinElmer, Inc.
Agilent Technologies, Inc.
Bio-Rad Laboratories, Inc.
Danaher Corporation
Abbott
Thermo Fisher Scientific
Standard BioTools

U.S. Microfluidics Market Report Segmentation
This report forecasts revenue growth at country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Nova one advisor, Inc. has segmented the U.S. Microfluidics market.
By Product

Microfluidic-based Devices
Microfluidic Components

Chips
Micro-pumps
Sensors
Others

By Application

Medical

Pharmaceuticals
Medical Devices
In-vitro Diagnostics
Others

Non-medical

By Material Type

Silicon
Glass
Polymer
PDMS
Others

By Technology

Lab-on-a-chip
Organs-on-chips
Continuous Flow Microfluidics
Optofluidics And Microfluidics
Acoustofluidics And Microfluidics
Electrophoresis And Microfluidics


Chapter 1. Methodology and Scope
1.1. Market Segmentation & Scope
1.2. Segment Definitions
1.2.1. Product
1.2.2. Application
1.2.3. Material Type
1.2.4. Technology
1.2.5. Estimates and forecasts timeline
1.3. Research Methodology
1.4. Information Procurement
1.4.1. Purchased database
1.4.2. nova one advisor’s internal database
1.4.3. Secondary sources
1.4.4. Primary research
1.4.5. Details of primary research
1.4.5.1. Data for primary interviews in U.S.
1.5. Information or Data Analysis
1.5.1. Data analysis models
1.6. Market Formulation & Validation
1.7. Model Details
1.7.1. Commodity flow analysis (Model 1)
1.7.2. Approach 1: Commodity flow approach
1.8. List of Secondary Sources
1.9. List of Primary Sources
1.10. ObjectivesChapter 2. Executive Summary
2.1. Market Outlook
2.2. Segment Outlook
2.2.1. Product Outlook
2.2.2. Application Outlook
2.2.3. Material Type Outlook
2.2.4. Technology Outlook
2.3. Competitive InsightsChapter 3. U.S. Microfluidics Market Variables, Trends & Scope
3.1. Market Lineage Outlook
3.1.1. Parent market outlook
3.1.2. Related/ancillary market outlook
3.2. Market Dynamics
3.2.1. Market Driver Analysis
3.2.1.1. Increasing demand for low-volume sample analysis
3.2.1.2. Growing penetration of microfluidics in diagnostics market
3.2.1.3. Introduction of advanced technologies
3.2.2. Market Restraint Analysis
3.2.2.1. High operational cost
3.2.2.2. Interfacing and integration
3.2.2.3. Complex fabrication process
3.3. U.S. Microfluidics Market Analysis Tools
3.3.1. Industry Analysis - Porter’s Five Forces
3.3.1.1. Threat of new entrant
3.3.1.2. Threat of substitutes
3.3.1.3. Bargaining power of buyers
3.3.1.4. Bargaining power of suppliers
3.3.1.5. Competitive rivalry
3.3.2. PESTEL Analysis
3.3.2.1. Political & legal landscape
3.3.2.2. Economic landscape
3.3.2.3. Technological landscapeChapter 4. U.S. Microfluidics Market: Product Estimates & Trend Analysis
4.1. U.S. Microfluidics Market: Product Dashboard
4.2. U.S. Microfluidics Market: Product Movement Analysis
4.3. U.S. Microfluidics Market Size & Forecasts and Trend Analyses, 2021 to 2033
4.4. Microfluidic-based Devices
4.4.1. Market estimates and forecasts 2021 to 2033
4.5. Microfluidic Components
4.5.1. Market estimates and forecasts 2021 to 2033
4.5.2. Chips
4.5.2.1. Market estimates and forecasts 2021 to 2033
4.5.3. Micro-pumps
4.5.3.1. Market estimates and forecasts 2021 to 2033
4.5.4. Sensors
4.5.4.1. Market estimates and forecasts 2021 to 2033
4.5.5. Others
4.5.5.1. Market estimates and forecasts 2021 to 2033Chapter 5. U.S. Microfluidics Market: Application Estimates & Trend Analysis
5.1. U.S. Microfluidics Market: Application Dashboard
5.2. U.S. Microfluidics Market: Application Movement Analysis
5.3. U.S. Microfluidics Market Size & Forecasts and Trend Analyses, 2021 to 2033
5.4. Medical
5.4.1. Market estimates and forecasts 2021 to 2033
5.4.2. Pharmaceuticals
5.4.2.1. Market estimates and forecasts 2021 to 2033
5.4.3. Medical Devices
5.4.3.1. Market estimates and forecasts 2021 to 2033
5.4.4. In-vitro Diagnostics
5.4.4.1. Market estimates and forecasts 2021 to 2033
5.4.5. Others
5.4.5.1. Market estimates and forecasts 2021 to 2033
5.5. Non-medical
5.5.1. Market estimates and forecasts 2021 to 2033Chapter 6. U.S. Microfluidics Market: Material Type Estimates & Trend Analysis
6.1. U.S. Microfluidics Market: Material Type Dashboard
6.2. U.S. Microfluidics Market: Material Type Movement Analysis
6.3. U.S. Microfluidics Market Size & Forecasts and Trend Analyses, 2021 to 2033
6.4. Silicon
6.4.1. Market estimates and forecasts 2021 to 2033
6.5. Glass
6.5.1. Market estimates and forecasts 2021 to 2033
6.6. Polymer
6.6.1. Market estimates and forecasts 2021 to 2033
6.7. PDMS
6.7.1. Market estimates and forecasts 2021 to 2033
6.8. Others
6.8.1. Market estimates and forecasts 2021 to 2033Chapter 7. U.S. Microfluidics Market: Technology Estimates & Trend Analysis
7.1. U.S. Microfluidics Market: Technology Dashboard
7.2. U.S. Microfluidics Market: Technology Movement Analysis
7.3. U.S. Microfluidics Market Size & Forecasts and Trend Analyses, 2021 to 2033
7.4. Lab-on-a-chip
7.4.1. Market estimates and forecasts 2021 to 2033
7.5. Organs-on-a-chip
7.5.1. Market estimates and forecasts 2021 to 2033
7.6. Continuous Flow Microfluidics
7.6.1. Market estimates and forecasts 2021 to 2033
7.7. Optofluidics and Microfluidics
7.7.1. Market estimates and forecasts 2021 to 2033
7.8. Acoustofluidics and Microfluidics
7.8.1. Market estimates and forecasts 2021 to 2033
7.9. Electrophoresis and Microfluidics
7.9.1. Market estimates and forecasts 2021 to 2033Chapter 8. Competitive Landscape
8.1. Recent Developments & Impact Analysis, By Key Market Participants
8.2. Company/Competition Categorization
8.3. Vendor Landscape
8.3.1. List of key distributors and channel partners
8.3.2. Key customers
8.3.3. Key company market share analysis, 2023
8.3.4. Illumina, Inc.
8.3.4.1. Company overview
8.3.4.2. Financial performance
8.3.4.3. Product benchmarking
8.3.4.4. Strategic initiatives
8.3.5. F. Hoffmann-La Roche Ltd
8.3.5.1. Company overview
8.3.5.2. Financial performance
8.3.5.3. Product benchmarking
8.3.5.4. Strategic initiatives
8.3.6. PerkinElmer, Inc.
8.3.6.1. Company overview
8.3.6.2. Financial performance
8.3.6.3. Product benchmarking
8.3.6.4. Strategic initiatives
8.3.7. Agilent Technologies, Inc.
8.3.7.1. Company overview
8.3.7.2. Financial performance
8.3.7.3. Product benchmarking
8.3.7.4. Strategic initiatives
8.3.8. Bio-Rad Laboratories, Inc.
8.3.8.1. Company overview
8.3.8.2. Financial performance
8.3.8.3. Product benchmarking
8.3.8.4. Strategic initiatives
8.3.9. Danaher Corporation
8.3.9.1. Company overview
8.3.9.2. Financial performance
8.3.9.3. Product benchmarking
8.3.9.4. Strategic initiatives
8.3.10. Abbott
8.3.10.1. Company overview
8.3.10.2. Financial performance
8.3.10.3. Product benchmarking
8.3.10.4. Strategic initiatives
8.3.11. Thermo Fisher Scientific
8.3.11.1. Company overview
8.3.11.2. Financial performance
8.3.11.3. Product benchmarking
8.3.11.4. Strategic initiatives
8.3.12. Standard BioTools
8.3.12.1. Company overview
8.3.12.2. Financial performance
8.3.12.3. Product benchmarking
8.3.12.4. Strategic initiatives

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