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What's Trending in Monoclonal Antibodies (Market by Structure [Chimeric, Humanized], by Target [EGFR, TNF, HER2, CD20,PD-1, Other] and by Disease [Autoimmune, Oncology, Neurological, Other])

What's Trending in Monoclonal Antibodies (Markets by Structure, by Target, and by Indication)

There are several types of monoclonal antibodies (mAbs) – large protein molecules produced by white blood cells (WBCs) that seek out and destroy harmful foreign substances – on the market and in development. What's Trending in Monoclonal Antibodies looks at the market for these, which are finding wide application in many areas of medicine and biologic science, by structure, by target, and by indication, including the following information: monoclonal antibody revenues by structure, 2017 and forecast 2022 (chimeric, humanized, human, Others); leading chimeric, humanized and human mAb products market, 2017-2022; monoclonal antibody revenues by target, 2017 and forecast 2022 (TNF, CD20, HER2, VEGF, EGFR, PD-1, PD-L1, TNFSF11, IL12/IL23, IL17, IL6, Others); and monoclonal antibody revenues by indication, 2017 and Forecast 2022 (Autoimmune, Oncology, Neurological, Respiratory, Cardio/Blood, Infection, Other).

The report also goes beyond broad indication category to provide detail on the rheumatoid arthritis, Crohn's disease/ulcerative colitis, psoriasis, other autoimmune, cancer (breast cancer, colon cancer, lymphoma, leukemia, myeloma, melanoma), multiple sclerosis, asthma, and macular degeneration mAb market segments, 2017-2022.

What's Trending in Monoclonal Antibodies also looks at the market in terms of regional markets (United States, Europe, rest of world, global market) and the competitive situation, including company profiles of market leaders such as AbbVie, Johnson & Johnson, and Roche.


  • Executive Summary
    • Overview
      • Table Monoclonal Antibody Market Development, 1986-2022
    • Scope and Methodology
    • Market Summary
      • Table Monoclonal Antibody Market, 2017-2022 ($ millions)
  • Introduction
    • The Development of Monoclonal Antibodies
      • Table Monoclonal Antibody Approvals by Year, FDA and EMA, 1990 through December 2017
    • Naming Monoclonal Antibodies
      • Table Monoclonal Antibody Source Identifiers
      • Table Monoclonal Antibody Disease or Target Class Identifiers
      • Table Examples of Monoclonal Antibodies by Name Origin
      • New Monoclonal Antibody Nomenclature Rules
        • Table USAN Requirements for Monoclonal Antibodies
    • DEVELOPMENT Outlook
      • Table Monoclonal Antibody Development Pipeline by Therapeutic Class and Phase, 2017
      • Table Monoclonal Antibody Development Pipeline by Therapeutic Class and Phase, 2017
      • Table Monoclonal Antibody Development Pipeline, Distribution of Projects by Therapeutic Class, 2017
      • Table Monoclonal Antibody Development Pipeline, Distribution of Projects by Phase, 2017
  • Monoclonal Antibody Markets by Structure
    • Table Monoclonal Antibodies by Structure - Mouse, Chimeric, Humanized, Human
    • Market Overview
      • Table Monoclonal Antibody Market by Structure, 2017 and Forecast 2022 ($ millions)
      • Table Monoclonal Antibody Market by Structure, 2017 and Forecast 2022 ($ millions)
      • Table Monoclonal Antibody Market Distribution by Structure, 2017 (%)
      • Table Monoclonal Antibody Market Distribution by Structure, 2022 (%)
      • Chimeric
        • Table Leading Products: Chimeric Structure mAb Market, 2017-2022 ($ millions)
      • Humanized
        • Table Leading Products: Humanized Structure mAb Market, 2017-2022 ($ millions)
      • Human
        • Table Leading Products: Human Structure mAb Market, 2017-2022 ($ millions)
  • Monoclonal Antibody Markets by Target
    • Market Overview
      • Table Monoclonal Antibodies by Target - TNF, CD20, HER2, VEGF, EGFR, PD-L1, PD-1, TNFSF11, IL12/IL23, IL17, IL6 Examples
      • Table Monoclonal Antibody Market by Target, 2017 and Forecast 2022 ($ millions)
      • Table Monoclonal Antibody Market by Target, 2017 and Forecast 2022 ($ millions)
      • Table Monoclonal Antibody Market Distribution by Target, 2017 (%)
      • Table Monoclonal Antibody Market Distribution by Target, 2022 (%)
  • Monoclonal Antibody Markets by Indication
    • Market Overview
      • Table Monoclonal Antibody Market by Indication, 2017 and Forecast 2022 ($ millions)
      • Table Monoclonal Antibody Market by Indication, 2017 and Forecast 2022 ($ millions)
      • Table Monoclonal Antibody Market Distribution by Indication, 2017 (%)
      • Table Monoclonal Antibody Market Distribution by Indication, 2022 (%)
      • Autoimmune Diseases
        • Table Rheumatoid Arthritis mAb Market, 2017-2022 ($ millions)
        • Table Crohn's Disease/Ulcerative Colitis mAb Market, 2017-2022 ($ millions)
        • Table Psoriasis mAb Market, 2017-2022 ($ millions)
        • Table Other Autoimmune Disease mAb Market, 2017-2022 ($ millions)
      • Oncology Indications
        • Table Cancer Treatment mAb Market by Type, 2017-2022 ($ millions)
        • Table Top 10 Cancer Indicated Monoclonal Antibodies, 2016 and 2017 Sales (millions $)
        • Table Top 10 Cancer Indicated Monoclonal Antibodies, 2016 and 2017 Sales (millions $)
      • Neurological Indications
        • Table Multiple Sclerosis mAb Market, 2017-2022 ($ millions)
      • Respiratory Treatments
        • Table Asthma mAb Market, 2017-2022 ($ millions)
    • Other Areas of Treatment
      • Table Macular Degeneration mAb Market, 2017-2022 ($ millions)
  • Market Summary
    • Market Influences
      • Global Demographics
        • Table Global Population, through 2050 (population in millions)
        • Table Global Population Trends, Total Population vs. Age 65+ Population, 2000-2050
      • Chronic Diseases
        • Table Mortality: Chronic vs. Acute, 2015
      • Cost Containment
        • Table The Cost of Monoclonal Antibodies
    • Reimbursement Landscape: A Deciding Factor for Success
    • The Biosimilar Movement
    • Regional Market Overview
      • Table Monoclonal Antibody Market Summary by Geographical Region, 2017-2022 ($ millions)
      • Table Monoclonal Antibody Market Summary by Geographic Region, 2017 ($ millions)
    • Leading Products
      • Table Leading Monoclonal Antibodies based on 2017 Sales ($ millions)
    • Market Breakdown of Monoclonal Antibodies
      • Table Monoclonal Antibody Market by Structure, 2017 and 2022 ($ millions)
      • Table Monoclonal Antibody Market by Target, 2017 and 2022 ($ millions)
      • Table Monoclonal Antibody Market by Indication, 2017 and 2022 ($ millions)
    • Competitor Summary
      • Genentech/Roche
      • AbbVie
      • Janssen Biotech/J&J
      • Bristol-Myers Squibb
      • Merck & Co.
      • Novartis
      • Amgen
      • Alexion
      • Biogen
      • Eli Lilly & Co.
        • Table Monoclonal Antibody Competitor Market Share, 2017 ($ millions)
  • Company Profiles
    • AbbVie
      • Table AbbVie Corporate Summary
    • Ablynx
      • Table Ablynx Corporate Summary
    • Agensys
      • Table Agensys (with Astellas) Corporate Summary
    • Alder Biopharmaceuticals
      • Table Alder Biopharmaceuticals Corporate Summary
    • Alexion Pharmaceuticals
      • Table Alexion Pharmaceuticals Corporate Summary
    • Allergan
      • Table Allergan Corporate Summary
    • Amgen
      • Table Amgen Corporate Summary
    • Aptevo Therapeutics
      • Table Aptevo Corporate Summary
    • AstraZeneca/MedImmune
      • Table AstraZeneca/MedImmune Corporate Summary
    • Bayer
      • Table Bayer Corporate Summary
    • Biocon Ltd
      • Table Biocon Corporate Summary
    • Biogen Inc.
      • Table Biogen Corporate Summary
    • BioInvent International
      • Table BioInvent Corporate Summary
    • Biotest AG
      • Table Biotest AG Corporate Summary
    • Boehringer Ingelheim GmbH
      • Table Boehringer Ingelheim Corporate Summary
    • CBT Pharmaceuticals
      • Table CBT Corporate Summary
    • Celgene
      • Table Celgene Corporate Summary
    • Celldex Therapeutics
      • Table Celldex Therapeutics Corporate Summary
    • Celltrion, Inc.
      • Table Celltrion Corporate Summary
    • Coherus BioSciences, Inc
      • Table Coherus Biosciences Corporate Summary
    • CytoDyn
      • Table CytoDyn Corporate Summary
    • Eisai
      • Table Eisai Corporate Summary
    • Eleven Biotherapeutics
      • Table Eleven Biotherapeutics Corporate Summary
    • Eli Lilly & Co.
      • Table Eli Lilly & Co. Corporate Summary
    • FibroGen Inc.
      • Table FibroGen Inc. Corporate Summary
    • Five Prime Therapeutics
      • Table Five Prime Therapeutics Corporate Summary
    • Fujifilm Kyowa Kirin Biologics
      • Table Fujifilm Kyowa Kirin Biologics Corporate Summary
    • Genmab A/S
      • Table Genmab A/S Corporate Summary
    • Gilead Sciences
      • Table Gilead Sciences Corporate Summary
    • GlaxoSmithKline plc
      • Table GlaxoSmithKline Corporate Summary
    • Humanigen, Inc. (previously KaloBios Pharmaceuticals)
      • Table Humanigen Inc. Corporate Summary
    • Immune Pharmaceuticals
      • Table Immune Pharmaceuticals Corporate Summary
    • ImmunoGen Inc.
      • Table ImmunoGen Inc. Corporate Summary
    • Immunomedics Inc.
      • Table Immunomedics Inc. Corporate Summary
    • Innate Pharma
      • Table Innate Pharma Corporate Summary
    • InterveXion Therapeutics
      • Table InterveXion Therapeutics Corporate Summary
    • Johnson & Johnson
      • Table Johnson & Johnson Corporate Summary
    • Kyowa Hakko Kirin Co, Ltd
      • Table Kyowa Hakko Kirin Corporate Summary
    • MacroGenics
      • Table MacroGenics Corporate Summary
    • Mapp Biopharmaceutical
      • Table Mapp Corporate Summary
    • Merck & Company
      • Table Merck Corporate Summary
    • Merrimack Pharmaceuticals
      • Table Merrimack Corporate Summary
    • Momenta Pharmaceuticals Inc.
      • Table Momenta Pharmaceuticals Corporate Summary
    • MorphoSys
      • Table MorphoSys Corporate Summary
    • Morphotek
      • Table Morphotek Corporate Summary
    • Mylan N.V.
      • Table Mylan Corporate Summary
    • Nascent Biotech
      • Table Nascent Biotech Corporate Summary
    • Neurimmune
      • Table Neurimmune Corporate Summary
    • Nordic Nanovector
      • Table Nordic Nanovector Corporate Summary
    • Novartis/Sandoz
      • Table Novartis/Sandoz Corporate Summary
    • Novimmune SA
      • Table Novimmune SA Corporate Summary
    • OncoMed Pharmaceuticals
      • Table OncoMed Pharmaceuticals Corporate Summary
    • OncoQuest
      • Table OncoQuest Corporate Summary
    • Oncternal Therapeutics
      • Table Oncternal Therapeutics Corporate Summary
    • Pfizer, Inc.
      • Table Pfizer Corporate Summary
    • Regeneron Pharmaceuticals
      • Table Regeneron Corporate Summary
    • Roche
      • Table Roche Corporate Summary
    • Samsung Bioepis Co Ltd
      • Table Samsung Bioepis Corporate Summary
    • Sanofi
      • Table Sanofi Corporate Summary
    • Seattle Genetics
      • Table Seattle Genetics Corporate Summary
    • Shire PLC
      • Table Shire PLC Corporate Summary
    • Sorrento Therapeutics
      • Table Sorrento Therapeutics Corporate Summary
    • TaiMed Biologics
      • Table TaiMed Biologics Corporate Summary
    • Takeda Oncology
      • Table Takeda Oncology Corporate Summary
    • TESARO
      • Table TESARO Corporate Summary
    • TEVA Pharmaceutical Industries Ltd
      • Table Teva Corporate Summary Corporate Summary
    • TG Therapeutics
      • Table TG Therapeutics Corporate Summary
    • ThromboGenics
      • Table ThromboGenics Corporate Summary
    • UCB S.A.
      • Table UCB S.A. Corporate Summary
    • Unum Therapeutics
      • Table Unum Therapeutics Corporate Summary
    • Vitaeris
      • Table Vitaeris Corporate Summary
    • XBiotech
      • Table XBiotech Corporate Summary
    • Xencor
      • Table Xencor Corporate Summary
    • XOMA
      • Table XOMA Corporate Summary
    • Y-mAbs Therapeutics
      • Table Y-mAbs Therapeutics Corporate Summary

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