Gene Synthesis (Research-use) Market Size, Share & Trends Analysis Report By Method (Solid-phase Synthesis, Chip-based Synthesis), By Service (Antibody DNA Synthesis), By Application, By End Use, By Research Phase, By Region, And Segment Forecasts, 2025 -
Description
Gene Synthesis (Research-use) Market Summary
The global gene synthesis (research-use) market size was estimated at USD 2.09 billion in 2024 and is projected to reach USD 8.39 billion by 2033, growing at a CAGR of 16.8% from 2025 to 2033. The surging investment by players in the synthetic biology field and supportive government laws & rules are expected to propel market growth.
Moreover, technological advances in gene synthesis procedures & techniques are also boosting the service demand over the forecast period. For instance, in April 2022, GenScript, a provider of life science research tools and services, announced the launch of the most advanced semiconductor chip for DNA synthesis in the field. This chip provides the highest throughput.
Technological Advancements Driving Faster and Cost-Efficient Gene Synthesis
Advancements in synthetic biology technologies are significantly transforming the gene synthesis (research-use) landscape, enabling faster, more accurate, and cost-efficient DNA synthesis processes. Continuous improvements in automation, error correction, and next-generation sequencing (NGS) integration have enhanced the precision and scalability of synthetic gene construction. These developments have substantially reduced turnaround times, allowing researchers to design and synthesize complex gene sequences within shorter timeframes. Moreover, the integration of AI-driven design tools and cloud-based bioinformatics platforms has streamlined workflow efficiency, further accelerated research timelines and reducing costs associated with manual interventions.
The adoption of high-throughput synthesis platforms and enzymatic DNA assembly methods has further strengthened production capabilities, enabling large-scale synthesis of genes for various research applications, including genomics, synthetic biology, and protein engineering. These technological innovations have not only improved synthesis accuracy but have also minimized contamination risks and material wastage. As a result, research institutions and biotechnology companies are increasingly leveraging these advancements to support pre-clinical studies, target validation, and the development of advanced therapeutic candidates such as mRNA vaccines and gene therapies.
Furthermore, ongoing R&D efforts aimed at enhancing the efficiency and affordability of gene synthesis technologies are expected to drive market expansion over the forecast period. The growing collaboration between academic institutions, private companies, and government research agencies is fostering the development of next-generation synthesis platforms capable of producing longer DNA fragments with higher fidelity. As the demand for customized genetic constructs continues to rise across applications in synthetic biology, diagnostics, and precision medicine, advancements in synthetic biology technologies are likely to remain a key driver supporting sustainable growth in the global gene synthesis (research-use) market.
Global Gene Synthesis (Research-Use) Market Report Segmentation
This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, grand view research has segmented the global gene synthesis (research-use) market report based on method, service, application, research phase, end use, and region.
The global gene synthesis (research-use) market size was estimated at USD 2.09 billion in 2024 and is projected to reach USD 8.39 billion by 2033, growing at a CAGR of 16.8% from 2025 to 2033. The surging investment by players in the synthetic biology field and supportive government laws & rules are expected to propel market growth.
Moreover, technological advances in gene synthesis procedures & techniques are also boosting the service demand over the forecast period. For instance, in April 2022, GenScript, a provider of life science research tools and services, announced the launch of the most advanced semiconductor chip for DNA synthesis in the field. This chip provides the highest throughput.
Technological Advancements Driving Faster and Cost-Efficient Gene Synthesis
Advancements in synthetic biology technologies are significantly transforming the gene synthesis (research-use) landscape, enabling faster, more accurate, and cost-efficient DNA synthesis processes. Continuous improvements in automation, error correction, and next-generation sequencing (NGS) integration have enhanced the precision and scalability of synthetic gene construction. These developments have substantially reduced turnaround times, allowing researchers to design and synthesize complex gene sequences within shorter timeframes. Moreover, the integration of AI-driven design tools and cloud-based bioinformatics platforms has streamlined workflow efficiency, further accelerated research timelines and reducing costs associated with manual interventions.
The adoption of high-throughput synthesis platforms and enzymatic DNA assembly methods has further strengthened production capabilities, enabling large-scale synthesis of genes for various research applications, including genomics, synthetic biology, and protein engineering. These technological innovations have not only improved synthesis accuracy but have also minimized contamination risks and material wastage. As a result, research institutions and biotechnology companies are increasingly leveraging these advancements to support pre-clinical studies, target validation, and the development of advanced therapeutic candidates such as mRNA vaccines and gene therapies.
Furthermore, ongoing R&D efforts aimed at enhancing the efficiency and affordability of gene synthesis technologies are expected to drive market expansion over the forecast period. The growing collaboration between academic institutions, private companies, and government research agencies is fostering the development of next-generation synthesis platforms capable of producing longer DNA fragments with higher fidelity. As the demand for customized genetic constructs continues to rise across applications in synthetic biology, diagnostics, and precision medicine, advancements in synthetic biology technologies are likely to remain a key driver supporting sustainable growth in the global gene synthesis (research-use) market.
Global Gene Synthesis (Research-Use) Market Report Segmentation
This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, grand view research has segmented the global gene synthesis (research-use) market report based on method, service, application, research phase, end use, and region.
- Method Outlook (Revenue, USD Million, 2021 - 2033)
- Solid-phase Synthesis
- Chip-based Synthesis
- PCR-based Enzyme Synthesis
- Service Outlook (Revenue, USD Million, 2021 - 2033)
- Antibody DNA Synthesis
- Viral DNA Synthesis
- Others
- Application Outlook (Revenue, USD Million, 2021 - 2033)
- Gene & Cell Therapy Development
- Vaccine Development
- Others
- Research Phase Outlook (Revenue, USD Million, 2021 - 2033)
- Pre-clinical
- Clinical
- End Use Outlook (Revenue, USD Million, 2021 - 2033)
- Biotechnology and pharmaceutical companies
- Academic and government research institutes
- Contract research organizations
- Regional Outlook (Revenue, USD Million, 2021 - 2033)
- North America
- U.S.
- Canada
- Mexico
- Europe
- UK
- Germany
- France
- Italy
- Spain
- Denmark
- Sweden
- Norway
- Asia Pacific
- China
- Japan
- India
- South Korea
- Australia
- Thailand
- Latin America
- Brazil
- Argentina
- Middle East & Africa
- South Africa
- Saudi Arabia
- UAE
- Kuwait
Table of Contents
180 Pages
- Chapter 1. Methodology and Scope
- 1.1. Market Segmentation and Scope
- 1.1.1. Method
- 1.1.2. Services
- 1.1.3. Application
- 1.1.4. Research Phase
- 1.1.5. End Use
- 1.2. Market Definitions
- 1.3. Information analysis
- 1.4. Market formulation & data visualization
- 1.5. Data validation & publishing
- 1.6. Information Procurement
- 1.6.1. Primary Others
- 1.7. Information or Data Analysis
- 1.8. Market Formulation & Validation
- 1.9. Market Model
- 1.10. Objectives
- Chapter 2. Executive Summary
- 2.1. Market Snapshot
- 2.2. Segment Snapshot
- 2.3. Competitive Landscape Snapshot
- Chapter 3. Market Variables, Trends, & Scope
- 3.1. Market Lineage Outlook
- 3.1.1. Parent Market Outlook
- 3.1.2. Related/Ancillary Market Outlook
- 3.2. Market Trends and Outlook
- 3.3. Market Dynamics
- 3.3.1. Market Driver Analysis
- 3.3.1.1. Rising investment in synthetic biology market
- 3.3.1.2. Advent of enzymatic DNA synthesis process
- 3.3.1.3. Technological advancements in the DNA synthesis platforms
- 3.3.1.4. Declining price of DNA synthesis & sequencing
- 3.3.2. Market Restraint Analysis
- 3.3.2.1. Lack of skilled professionals
- 3.3.2.2. Misuse of gene synthesis
- 3.4. Industry Analysis Tools
- 3.4.1. Porter’s Five Forces Analysis
- 3.4.2. PESTLE Analysis
- Chapter 4. Gene Synthesis (Research Use) Market: Method Estimates & Trend Analysis
- 4.1. Method Segment Dashboard
- 4.2. Global Gene Synthesis (Research Use) Market: Method Movement Analysis
- 4.3. Global Gene Synthesis (Research Use) Market Size & Trend Analysis, by Method, 2021 to 2033 (USD Million)
- 4.4. Solid-Phase Synthesis
- 4.4.1. Solid Phase Synthesis Market, 2021 - 2033 (USD Million)
- 4.5. Chip Based Synthesis
- 4.5.1. Chip Based Synthesis Market, 2021 - 2033 (USD Million)
- 4.6. PCR-based Enzyme Synthesis
- 4.6.1. PCR based Enzyme Synthesis Market, 2021 - 2033 (USD Million)
- Chapter 5. Gene Synthesis (Research Use) Market: Services Estimates & Trend Analysis
- 5.1. Services Segment Dashboard
- 5.2. Global Gene Synthesis (Research Use) Market: Services Movement Analysis
- 5.3. Global Gene Synthesis (Research Use) Market Size & Trend Analysis, by Services, 2021 to 2033 (USD Million)
- 5.4. Antibody DNA Synthesis
- 5.4.1. Antibody DNA Synthesis Market, 2021 - 2033 (USD Million)
- 5.5. Viral DNA Synthesis
- 5.5.1. Viral DNA Synthesis Market, 2021 - 2033 (USD Million)
- 5.6. Others
- 5.6.1. Others Market, 2021 - 2033 (USD Million)
- Chapter 6. Gene Synthesis (Research Use) Market: Application Estimates & Trend Analysis
- 6.1. Application Segment Dashboard
- 6.2. Global Gene Synthesis (Research Use) Market: Application Movement Analysis
- 6.3. Global Gene Synthesis (Research Use) Market Size & Trend Analysis, by Application, 2021 to 2033 (USD Million)
- 6.4. Gene & Cell Therapy Development
- 6.4.1. Gene & Cell Therapy Development Market, 2021 - 2033 (USD Million)
- 6.5. Vaccine Development
- 6.5.1. Vaccine Development Market, 2021 - 2033 (USD Million)
- 6.6. Others
- 6.6.1. Others Market, 2021 - 2033 (USD Million)
- Chapter 7. Gene Synthesis (Research Use) Market: Research Phase Estimates & Trend Analysis
- 7.1. Research Phase Segment Dashboard
- 7.2. Global Gene Synthesis (Research Use) Market: Research Phase Movement Analysis
- 7.3. Global Gene Synthesis (Research Use) Market Size & Trend Analysis, by Research Phase, 2021 to 2033 (USD Million)
- 7.4. Preclinical
- 7.4.1. Preclinical Market, 2021 - 2033 (USD Million)
- 7.5. Clinical
- 7.5.1. Clinical Market, 2021 - 2033 (USD Million)
- Chapter 8. Gene Synthesis (Research Use) Market: End Use Estimates & Trend Analysis
- 8.1. End Use Segment Dashboard
- 8.2. Global Gene Synthesis (Research Use) Market: End Use Movement Analysis
- 8.3. Global Gene Synthesis (Research Use) Market Size & Trend Analysis, by End Use, 2021 to 2033 (USD Million)
- 8.4. Global Gene Synthesis (Research Use) Market: End Use Movement Analysis
- 8.5. Biopharmaceutical & Pharmaceutical Companies
- 8.5.1. Biopharmaceutical & Pharmaceutical Companies Market, 2021 - 2033 (USD Million)
- 8.6. Academic & Government Research Institutes
- 8.6.1. Academic & Research Institutes Market, 2021 - 2033 (USD Million)
- 8.7. Contract Research Organizations
- 8.7.1. Contract Research Organizations Market, 2021 - 2033 (USD Million)
- Chapter 9. Gene Synthesis (Research Use) Market: Region Estimates & Trend Analysis
- 9.1. Gene Synthesis (Research Use) Market: Region Outlook
- 9.2. North America
- 9.2.1. North America gene synthesis (research use) market estimates and forecast, 2021 - 2033 (USD Million)
- 9.2.2. U.S.
- 9.2.2.1. Key Country Dynamics
- 9.2.2.2. Competitive Scenario
- 9.2.2.3. Regulatory Framework
- 9.2.2.4. U.S. gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.2.3. Canada
- 9.2.3.1. Key Country Dynamics
- 9.2.3.2. Competitive Scenario
- 9.2.3.3. Regulatory Framework
- 9.2.3.4. Canada gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.2.4. Mexico
- 9.2.4.1. Key Country Dynamics
- 9.2.4.2. Competitive Scenario
- 9.2.4.3. Regulatory Framework
- 9.2.4.4. Mexico gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.3. Europe
- 9.3.1. Europe gene synthesis (research use) market estimates and forecast, 2021 - 2033 (USD Million)
- 9.3.2. Germany
- 9.3.2.1. Key Country Dynamics
- 9.3.2.2. Competitive Scenario
- 9.3.2.3. Regulatory Framework
- 9.3.2.4. Germany gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.3.3. France
- 9.3.3.1. Key Country Dynamics
- 9.3.3.2. Competitive Scenario
- 9.3.3.3. Regulatory Framework
- 9.3.3.4. France gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.3.4. UK
- 9.3.4.1. Key Country Dynamics
- 9.3.4.2. Competitive Scenario
- 9.3.4.3. Regulatory Framework
- 9.3.4.4. UK gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.3.5. Italy
- 9.3.5.1. Key Country Dynamics
- 9.3.5.2. Competitive Scenario
- 9.3.5.3. Regulatory Framework
- 9.3.5.4. Italy gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.3.6. Spain
- 9.3.6.1. Key Country Dynamics
- 9.3.6.2. Competitive Scenario
- 9.3.6.3. Regulatory Framework
- 9.3.6.4. Spain gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.3.7. Denmark
- 9.3.7.1. Key Country Dynamics
- 9.3.7.2. Competitive Scenario
- 9.3.7.3. Regulatory Framework
- 9.3.7.4. Denmark gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.3.8. Sweden
- 9.3.8.1. Key Country Dynamics
- 9.3.8.2. Competitive Scenario
- 9.3.8.3. Regulatory Framework
- 9.3.8.4. Sweden gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.3.9. Norway
- 9.3.9.1. Key Country Dynamics
- 9.3.9.2. Competitive Scenario
- 9.3.9.3. Regulatory Framework
- 9.3.9.4. Norway gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.4. Asia Pacific
- 9.4.1. Asia Pacific gene synthesis (research use) market estimates and forecast, 2021 - 2033 (USD Million)
- 9.4.2. Japan
- 9.4.2.1. Key Country Dynamics
- 9.4.2.2. Competitive Scenario
- 9.4.2.3. Regulatory Framework
- 9.4.2.4. Japan gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.4.3. China
- 9.4.3.1. Key Country Dynamics
- 9.4.3.2. Competitive Scenario
- 9.4.3.3. Regulatory Framework
- 9.4.3.4. China gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.4.4. India
- 9.4.4.1. Key Country Dynamics
- 9.4.4.2. Competitive Scenario
- 9.4.4.3. Regulatory Framework
- 9.4.4.4. India gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.4.5. Australia
- 9.4.5.1. Key Country Dynamics
- 9.4.5.2. Competitive Scenario
- 9.4.5.3. Regulatory Framework
- 9.4.5.4. Australia gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.4.6. South Korea
- 9.4.6.1. Key Country Dynamics
- 9.4.6.2. Competitive Scenario
- 9.4.6.3. Regulatory Framework
- 9.4.6.4. South Korea gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.4.7. Thailand
- 9.4.7.1. Key Country Dynamics
- 9.4.7.2. Competitive Scenario
- 9.4.7.3. Regulatory Framework
- 9.4.7.4. Thailand gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.5. Latin America
- 9.5.1. Latin America gene synthesis (research use) market Estimates And Forecast, 2021 - 2033 (USD Million)
- 9.5.2. Brazil
- 9.5.2.1. Key Country Dynamics
- 9.5.2.2. Competitive Scenario
- 9.5.2.3. Regulatory Framework
- 9.5.2.4. Brazil gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.5.3. Argentina
- 9.5.3.1. Key Country Dynamics
- 9.5.3.2. Competitive Scenario
- 9.5.3.3. Regulatory Framework
- 9.5.3.4. Argentina gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.6. Middle East & Africa
- 9.6.1. Middle East & Africa gene synthesis (research use) market Estimates And Forecast, 2021 - 2033 (USD Million)
- 9.6.2. Saudi Arabia
- 9.6.2.1. Key Country Dynamics
- 9.6.2.2. Competitive Scenario
- 9.6.2.3. Regulatory Framework
- 9.6.2.4. Saudi Arabia gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.6.3. South Africa
- 9.6.3.1. Key Country Dynamics
- 9.6.3.2. Competitive Scenario
- 9.6.3.3. Regulatory Framework
- 9.6.3.4. South Africa gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.6.4. UAE
- 9.6.4.1. Key Country Dynamics
- 9.6.4.2. Competitive Scenario
- 9.6.4.3. Regulatory Framework
- 9.6.4.4. UAE gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- 9.6.5. Kuwait
- 9.6.5.1. Key Country Dynamics
- 9.6.5.2. Competitive Scenario
- 9.6.5.3. Regulatory Framework
- 9.6.5.4. Kuwait gene synthesis market estimates and forecast, 2021 - 2033 (USD Million)
- Chapter 10. Competitive Landscape
- 10.1. Company Categorization
- 10.2. Strategy Mapping
- 10.3. Company Position Analysis, 2024
- 10.4. Company Profiles/Listing
- 10.4.1. GenScript
- 10.4.1.1. Overview
- 10.4.1.2. Financial Performance
- 10.4.1.3. Method Benchmarking
- 10.4.1.4. Strategic Initiatives
- 10.4.2. Azenta, Inc. (GENEWIZ)
- 10.4.2.1. Overview
- 10.4.2.2. Financial Performance
- 10.4.2.3. Method Benchmarking
- 10.4.2.4. Strategic Initiatives
- 10.4.3. Boster Biological Technology
- 10.4.3.1. Overview
- 10.4.3.2. Financial Performance
- 10.4.3.3. Method Benchmarking
- 10.4.3.4. Strategic Initiatives
- 10.4.4. Twist Bioscience
- 10.4.4.1. Overview
- 10.4.4.2. Financial Performance
- 10.4.4.3. Method Benchmarking
- 10.4.4.4. Strategic Initiatives
- 10.4.5. ProteoGenix, Inc
- 10.4.5.1. Overview
- 10.4.5.2. Financial Performance
- 10.4.5.3. Method Benchmarking
- 10.4.5.4. Strategic Initiatives
- 10.4.6. Biomatik.
- 10.4.6.1. Overview
- 10.4.6.2. Financial Performance
- 10.4.6.3. Method Benchmarking
- 10.4.6.4. Strategic Initiatives
- 10.4.7. ProMab Biotechnologies, Inc.
- 10.4.7.1. Overview
- 10.4.7.2. Financial Performance
- 10.4.7.3. Method Benchmarking
- 10.4.7.4. Strategic Initiatives
- 10.4.8. Thermo Fisher Scientific, Inc
- 10.4.8.1. Overview
- 10.4.8.2. Financial Performance
- 10.4.8.3. Method Benchmarking
- 10.4.8.4. Strategic Initiatives
- 10.4.9. Integrated DNA Technologies, Inc. (Danaher)
- 10.4.9.1. Overview
- 10.4.9.2. Financial Performance
- 10.4.9.3. Method Benchmarking
- 10.4.9.4. Strategic Initiatives
- 10.4.10. OriGene Technologies, Inc.
- 10.4.10.1. Overview
- 10.4.10.2. Financial Performance
- 10.4.10.3. Method Benchmarking
- 10.4.10.4. Strategic Initiatives
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