Targeted DNA RNA Sequencing

Global Targeted DNA RNA Sequencing Market to Reach US$31.4 Billion by 2030

The global market for Targeted DNA RNA Sequencing estimated at US$11.7 Billion in the year 2024, is expected to reach US$31.4 Billion by 2030, growing at a CAGR of 17.9% over the analysis period 2024-2030. NGS, one of the segments analyzed in the report, is expected to record a 15.8% CAGR and reach US$17.0 Billion by the end of the analysis period. Growth in the Other Products segment is estimated at 20.7% CAGR over the analysis period.

The U.S. Market is Estimated at US$3.2 Billion While China is Forecast to Grow at 23.2% CAGR

The Targeted DNA RNA Sequencing market in the U.S. is estimated at US$3.2 Billion in the year 2024. China, the world`s second largest economy, is forecast to reach a projected market size of US$6.9 Billion by the year 2030 trailing a CAGR of 23.2% over the analysis period 2024-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 13.5% and 16.0% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 14.2% CAGR.

Global Targeted DNA RNA Sequencing Market – Key Trends & Drivers Summarized

Why Is Targeted DNA RNA Sequencing Gaining Ground Over Whole Genome and Transcriptome Approaches?

In the era of precision medicine and high-throughput genomics, targeted DNA and RNA sequencing has emerged as a practical and efficient alternative to whole genome and transcriptome sequencing. By focusing on specific genomic regions or transcript subsets of interest, this method offers a highly cost-effective, scalable, and clinically relevant way to interrogate genetic variation, expression profiles, and molecular biomarkers. Unlike whole genome sequencing, which can generate enormous amounts of irrelevant data and require intensive computational resources, targeted sequencing enables researchers and clinicians to zero in on known genes, regulatory elements, or mutation hotspots linked to disease pathways. In oncology, for example, targeted sequencing panels allow clinicians to identify actionable mutations across cancer-relevant genes with faster turnaround and better interpretability. In infectious disease research, targeted RNA sequencing enables pathogen-specific transcript analysis, aiding in strain identification and drug resistance profiling. Additionally, hereditary disease diagnostics, pharmacogenomics, and immune repertoire profiling are increasingly reliant on targeted assays for precise, repeatable insights. As the healthcare and life sciences industries seek clinically actionable, time-sensitive genetic data, targeted sequencing methods are bridging the gap between research and clinical utility, offering the depth and specificity needed to answer high-impact biological questions without the burden of excessive data noise.

How Are Technology Innovations Enhancing the Efficiency and Accuracy of Targeted Sequencing?

Advancements in sequencing chemistry, probe design, amplification protocols, and bioinformatics are driving significant improvements in the sensitivity, specificity, and throughput of targeted DNA and RNA sequencing. Techniques such as hybrid capture and amplicon-based enrichment are becoming more refined, enabling accurate targeting of low-frequency variants and structurally complex genomic regions. Adaptive sampling technologies now allow for real-time target selection on nanopore sequencing platforms, reducing wasted reads and increasing efficiency. Multiplexed library preparation kits and automation-friendly workflows are cutting down turnaround times and reducing sample handling errors, while low-input and FFPE-compatible kits are expanding usability in clinical and degraded samples. On the data analysis front, integrated bioinformatics pipelines and AI-powered variant callers are enhancing the reliability of read mapping, mutation detection, and transcript quantification, even in difficult-to-sequence regions. Cloud-based platforms are facilitating collaborative research, secure data storage, and streamlined reporting for clinical labs. Furthermore, the development of dual DNA/RNA panels is supporting integrated genomic and transcriptomic profiling from a single sample, which is particularly useful in oncology and immune profiling applications. Combined with increasing read accuracy, faster sequencers, and more affordable reagent kits, these innovations are making targeted sequencing not just a focused method, but a technically sophisticated and widely deployable solution for precision diagnostics and translational research.

Where Is Targeted DNA RNA Sequencing Being Adopted, and What Are the Emerging Use Cases?

Targeted DNA and RNA sequencing is being adopted across a wide range of clinical, academic, and industrial settings, with applications extending well beyond traditional genomics research. In clinical oncology, targeted sequencing panels are now routine for solid tumors and hematologic malignancies, helping identify actionable mutations, guide therapy selection, and monitor minimal residual disease. In reproductive health and rare disease diagnostics, targeted assays enable rapid screening for pathogenic variants across defined gene sets, improving diagnostic yield while reducing costs and turnaround times. In infectious disease research, pathogen-specific RNA sequencing is being used for rapid identification of emerging variants, antimicrobial resistance markers, and transcriptional responses to therapeutic agents. The immunology and vaccine development fields are leveraging targeted T-cell and B-cell receptor sequencing to study immune repertoires and response dynamics. Beyond healthcare, agrigenomics researchers use targeted sequencing to analyze plant and livestock traits, while in environmental monitoring, RNA panels help track microbial activity in ecosystems and industrial bioreactors. Drug development pipelines are increasingly incorporating targeted sequencing for biomarker discovery and companion diagnostic development. Geographically, adoption is strong in North America and Western Europe, where clinical genomics is more mature, while Asia-Pacific is witnessing rapid growth driven by expanding research funding, genomics startup ecosystems, and government initiatives in precision medicine. With sequencing instruments becoming more portable and data analysis more accessible, small to mid-sized labs in academia and diagnostics are also embracing targeted methods, expanding market reach and diversity of use cases.

What’s Fueling the Accelerated Growth of the Global Targeted DNA RNA Sequencing Market?

The growth of the targeted DNA RNA sequencing market is being driven by the convergence of clinical demand, research prioritization, cost-efficiency, and rapid technological maturation. The global rise in chronic diseases, cancer incidence, and interest in personalized medicine is increasing demand for quick, actionable genetic insights that targeted sequencing is well-equipped to provide. Compared to whole genome approaches, targeted methods offer significantly lower sequencing costs, reduced data complexity, and faster reporting timelines—making them more accessible for routine diagnostics, especially in resource-constrained settings. The integration of multi-omic strategies and growing interest in spatial and single-cell sequencing are further fueling adoption, as researchers seek ways to combine high-throughput precision with data relevance. Regulatory approvals of targeted NGS panels for clinical use, especially in oncology, pharmacogenomics, and inherited diseases, are validating the utility of these approaches and accelerating clinical deployment. Rising funding in genomics research, coupled with government initiatives aimed at national sequencing projects and biobank development, is broadening the infrastructure and support ecosystem. Partnerships between academic institutions, biotech firms, and diagnostic labs are fostering innovation and commercialization of specialized panels tailored for specific populations or diseases. At the same time, the availability of automated, user-friendly NGS platforms and integrated analysis software is democratizing access for mid-sized and decentralized laboratories. As demand for precision, speed, and affordability grows in molecular diagnostics and translational research, targeted DNA RNA sequencing is positioned to play an increasingly central role in shaping the next generation of genomic medicine.

SCOPE OF STUDY:

The report analyzes the Targeted DNA RNA Sequencing market in terms of units by the following Segments, and Geographic Regions/Countries:

Segments:
Product (NGS, Others); Workflow (Pre-sequencing, Sequencing, Data); Type (DNA-based Targeted Sequencing, RNA-based Targeted Sequencing); Application (Human Biomedical Research, Plant & Animal Sciences, Drug Discovery, Others); End-Use (Academic Research, Hospitals & Clinics, Pharma & Biotech Companies, Others)

Geographic Regions/Countries:
World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.

Select Competitors (Total 43 Featured) -

• Agilent Technologies, Inc.
• Azenta Life Sciences (GENEWIZ)
• BGI Genomics
• Bio-Rad Laboratories, Inc.
• CD Genomics
• Element Biosciences
• F. Hoffmann-La Roche Ltd
• Genomatix Software GmbH
• GeneDx
• HudsonAlpha Institute for Biotechnology
• Illumina, Inc.
• Integrated DNA Technologies, Inc.
• Macrogen, Inc.
• New England Biolabs
• Novogene Corporation
• Nugen Technologies, Inc.
• Oxford Nanopore Technologies plc
• Pacific Biosciences of California, Inc.
• Paragon Genomics
• PerkinElmer, Inc.
• PierianDx
• QIAGEN N.V.

TARIFF IMPACT FACTOR

Our new release incorporates impact of tariffs on geographical markets as we predict a shift in competitiveness of companies based on HQ country, manufacturing base, exports and imports (finished goods and OEM). This intricate and multifaceted market reality will impact competitors by artificially increasing the COGS, reducing profitability, reconfiguring supply chains, amongst other micro and macro market dynamics.

We are diligently following expert opinions of leading Chief Economists (14,949), Think Tanks (62), Trade & Industry bodies (171) worldwide, as they assess impact and address new market realities for their ecosystems. Experts and economists from every major country are tracked for their opinions on tariffs and how they will impact their countries.

We expect this chaos to play out over the next 2-3 months and a new world order is established with more clarity. We are tracking these developments on a real time basis.

As we release this report, U.S. Trade Representatives are pushing their counterparts in 183 countries for an early closure to bilateral tariff negotiations. Most of the major trading partners also have initiated trade agreements with other key trading nations, outside of those in the works with the United States. We are tracking such secondary fallouts as supply chains shift.

To our valued clients, we say, we have your back. We will present a simplified market reassessment by incorporating these changes!

APRIL 2025: NEGOTIATION PHASE

Our April release addresses the impact of tariffs on the overall global market and presents market adjustments by geography. Our trajectories are based on historic data and evolving market impacting factors.

JULY 2025 FINAL TARIFF RESET

Complimentary Update: Our clients will also receive a complimentary update in July after a final reset is announced between nations. The final updated version incorporates clearly defined Tariff Impact Analyses.

Reciprocal and Bilateral Trade & Tariff Impact Analyses:

USA
CHINA
MEXICO
CANADA
EU
JAPAN
INDIA
176 OTHER COUNTRIES.

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