Long Read Sequencing

Global Long Read Sequencing Market to Reach US$3.8 Billion by 2030

The global market for Long Read Sequencing estimated at US$756.8 Million in the year 2024, is expected to reach US$3.8 Billion by 2030, growing at a CAGR of 30.8% over the analysis period 2024-2030. Instruments, one of the segments analyzed in the report, is expected to record a 32.5% CAGR and reach US$2.6 Billion by the end of the analysis period. Growth in the Consumables segment is estimated at 28.3% CAGR over the analysis period.

The U.S. Market is Estimated at US$206.2 Million While China is Forecast to Grow at 40.4% CAGR

The Long Read Sequencing market in the U.S. is estimated at US$206.2 Million in the year 2024. China, the world`s second largest economy, is forecast to reach a projected market size of US$973.2 Million by the year 2030 trailing a CAGR of 40.4% over the analysis period 2024-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 24.7% and 27.9% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 26.1% CAGR.

Global Long Read Sequencing Market – Key Trends & Drivers Summarized

What Is Long Read Sequencing and Why Is It Revolutionizing Genomics?
Long read sequencing, also known as third-generation sequencing, refers to advanced DNA sequencing technologies capable of reading extended nucleotide sequences in a single pass—often exceeding tens of thousands of base pairs. Unlike short-read sequencing, which reads DNA fragments in small bits (typically 100–300 base pairs), long read sequencing provides a more complete and accurate picture of the genome by spanning repetitive and complex regions that short-read technologies cannot resolve effectively. This makes it especially valuable for de novo genome assembly, structural variant detection, epigenetic analysis, and studying previously uncharacterized genomic regions.

Technologies from providers like Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT) are at the forefront of this field, offering highly scalable and increasingly cost-effective solutions for long read analysis. These platforms are transforming genomics research and clinical diagnostics by enabling comprehensive insights into human diseases, microbial communities, plant genomics, and cancer genomics. Their ability to capture full-length transcripts and methylation patterns also enhances functional genomics and transcriptome profiling. As the demand for more precise and complete genetic data grows, long read sequencing is playing an increasingly central role in modern molecular biology.

What Innovations and Use Cases Are Accelerating the Adoption of Long Read Sequencing?
The evolution of long read sequencing is being shaped by continuous advancements in read accuracy, throughput, and portability. Recent iterations of PacBio`s HiFi reads and Oxford Nanopore’s Q20+ chemistry have significantly improved the base-calling accuracy of long reads, making them competitive with short-read platforms in both precision and reliability. These innovations have expanded long read sequencing’s applicability across clinical diagnostics, personalized medicine, and rare disease identification, where accurate detection of structural variants, gene fusions, and large insertions or deletions is critical.

Long read technologies are also being increasingly used in microbiome analysis and metagenomics, where the ability to fully resolve microbial genomes from complex samples enhances the understanding of microbial diversity, antibiotic resistance, and pathogen surveillance. In oncology, long reads are aiding in the detection of tumor heterogeneity and somatic structural variations that inform treatment decisions. The portability of platforms like ONT’s MinION device is enabling in-field and point-of-care sequencing for infectious disease tracking, environmental genomics, and food safety testing. Furthermore, long read sequencing is being integrated into hybrid sequencing strategies—combining long and short reads—to balance cost, accuracy, and depth of coverage, particularly in population-scale genome projects.

What Factors Are Fueling the Expansion of the Long Read Sequencing Market?
The growth in the global long read sequencing market is driven by several factors, including increasing demand for comprehensive genomic insights, declining sequencing costs, and expanding applications in clinical and agricultural genomics. As researchers and clinicians seek to decode complex genetic regions and structural variations that short-read sequencing often misses, long read platforms are being increasingly adopted for more accurate and complete genomic profiling. This demand is particularly pronounced in oncology, rare disease diagnostics, neurogenetics, and prenatal screening, where genomic complexity requires high-resolution analysis.

In addition, the rising prevalence of personalized and precision medicine is catalyzing the need for technologies that can deliver actionable insights from individual genomic data. Government-backed genomic initiatives, such as national population sequencing projects and rare disease registries, are also contributing to market growth by incorporating long read platforms to ensure data completeness and utility. Moreover, growing investments in agricultural biotechnology and plant genomics are expanding the use of long reads in crop trait analysis, genome editing validation, and biodiversity studies. The continuous innovation in sequencing chemistry, device miniaturization, and cloud-based bioinformatics is lowering the entry barrier for new users, further accelerating market adoption across academic, clinical, and commercial domains.

SCOPE OF STUDY:

The report analyzes the Long Read Sequencing market in terms of units by the following Segments, and Geographic Regions/Countries:

Segments:
Product (Instruments, Consumables, Services); Technology (Single Molecule Real Time Sequencing, Nanopore Sequencing, Others); Workflow (Pre-sequencing, Sequencing, Data Analysis); Application (Whole Genome Sequencing, Targeted Sequencing, Metagenomics, RNA Sequencing, Epigenetics, Others); End-Use (Academic & Research Institutes, Hospitals & Clinics, Pharma & Biotech Companies, Others)

Geographic Regions/Countries:
World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.

Select Competitors (Total 42 Featured) -

• 10x Genomics
• Agilent Technologies
• BGI Genomics
• Bionano Genomics
• CD Genomics
• Element Biosciences
• FG Technologies
• GENEWIZ (Azenta Life Sciences)
• Illumina, Inc.
• MGI Tech Co., Ltd.
• MicrobesNG
• Oxford Nanopore Technologies
• Pacific Biosciences (PacBio)
• Qiagen
• Quantapore, Inc.
• Singular Genomics
• Stratos Genomics
• Thermo Fisher Scientific
• Ultima Genomics
• Universal Sequencing Technology Corp.

TARIFF IMPACT FACTOR

Our new release incorporates impact of tariffs on geographical markets as we predict a shift in competitiveness of companies based on HQ country, manufacturing base, exports and imports (finished goods and OEM). This intricate and multifaceted market reality will impact competitors by artificially increasing the COGS, reducing profitability, reconfiguring supply chains, amongst other micro and macro market dynamics.

We are diligently following expert opinions of leading Chief Economists (14,949), Think Tanks (62), Trade & Industry bodies (171) worldwide, as they assess impact and address new market realities for their ecosystems. Experts and economists from every major country are tracked for their opinions on tariffs and how they will impact their countries.

We expect this chaos to play out over the next 2-3 months and a new world order is established with more clarity. We are tracking these developments on a real time basis.

As we release this report, U.S. Trade Representatives are pushing their counterparts in 183 countries for an early closure to bilateral tariff negotiations. Most of the major trading partners also have initiated trade agreements with other key trading nations, outside of those in the works with the United States. We are tracking such secondary fallouts as supply chains shift.

To our valued clients, we say, we have your back. We will present a simplified market reassessment by incorporating these changes!

APRIL 2025: NEGOTIATION PHASE

Our April release addresses the impact of tariffs on the overall global market and presents market adjustments by geography. Our trajectories are based on historic data and evolving market impacting factors.

JULY 2025 FINAL TARIFF RESET

Complimentary Update: Our clients will also receive a complimentary update in July after a final reset is announced between nations. The final updated version incorporates clearly defined Tariff Impact Analyses.

Reciprocal and Bilateral Trade & Tariff Impact Analyses:

USA
CHINA
MEXICO
CANADA
EU
JAPAN
INDIA
176 OTHER COUNTRIES.

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