Gene Therapy

Global Gene Therapy Market to Reach US$6.0 Billion by 2030

The global market for Gene Therapy estimated at US$1.7 Billion in the year 2024, is expected to reach US$6.0 Billion by 2030, growing at a CAGR of 23.0% over the analysis period 2024-2030. Viral, one of the segments analyzed in the report, is expected to record a 23.3% CAGR and reach US$5.5 Billion by the end of the analysis period. Growth in the Non-Viral segment is estimated at 20.8% CAGR over the analysis period.

The U.S. Market is Estimated at US$928.9 Million While China is Forecast to Grow at 29.5% CAGR

The Gene Therapy market in the U.S. is estimated at US$928.9 Million in the year 2024. China, the world`s second largest economy, is forecast to reach a projected market size of US$216.3 Million by the year 2030 trailing a CAGR of 29.5% over the analysis period 2024-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 20.1% and 22.1% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 22.0% CAGR.

Global Gene Therapy Market - Key Trends & Drivers Summarized

Revolutionizing Medicine: How Gene Therapy Is Redefining Treatment Paradigms?

Gene therapy represents a groundbreaking medical approach that involves modifying the genetic material within a person`s cells to treat or prevent disease. This innovative therapy can potentially provide a cure for a range of disorders by correcting defective genes responsible for disease development. Techniques used in gene therapy include replacing a mutated gene that causes disease with a healthy copy, inactivating a mutated gene that is functioning improperly, or introducing a new or modified gene into the body to help treat a disease. These methods are primarily delivered through vectors, typically viruses that have been genetically altered to carry human DNA. The potential of gene therapy extends from treating hereditary diseases like cystic fibrosis and hemophilia to more complex conditions such as cancer, heart disease, and HIV/AIDS. Its development represents a significant leap from traditional treatments, offering hope for long-term or permanent therapeutic effects after a single treatment course.

Pushing the Boundaries: Next-Generation Techniques Enhancing Gene Therapy

Technological advancements have significantly improved the precision and efficacy of gene therapy. The advent of CRISPR-Cas9 and other gene-editing technologies has provided scientists with tools of unprecedented accuracy for editing DNA at specific locations, allowing for the correction of mutations at their source. These advancements not only increase the potential for successful treatment outcomes but also reduce the risks associated with older gene therapy methods, such as unintended effects on other parts of the genome. Additionally, innovations in vector technology, particularly in the development of non-viral delivery systems, are overcoming previous challenges related to safety and immune response management. These enhancements in delivery systems ensure that therapeutic genes reach the target cells more effectively and work as intended, which is critical for the treatment of diseases that require cellular-level interventions.

Navigating Complexities: The Challenges and Ethical Dilemmas of Modern Gene Therapy

Despite its promising potential, gene therapy faces several challenges and ethical considerations that influence its clinical application. One of the primary challenges is ensuring long-term safety and efficacy, as the long-term effects of gene editing are still not fully understood. Questions remain about the potential for off-target effects, where unintended parts of the genome may be edited, leading to unforeseen consequences. Additionally, the immune system`s response to viral vectors can complicate delivery and effectiveness, particularly for patients who might have pre-existing immunity to the viruses used as vectors. Ethical concerns also play a significant role, particularly regarding germline editing, which could allow genetic changes to be passed down to future generations. The debate centers on the implications of making genetic modifications that could alter human evolution, underscoring the need for rigorous ethical standards and regulatory oversight in the development and application of gene therapy treatments.

Fueling a Medical Revolution: Key Drivers Behind the Expanding Gene Therapy Market

The growth in the gene therapy market is driven by several factors, including significant advancements in genetic research and biotechnological techniques. The increasing prevalence of genetic disorders and high unmet need for novel treatments in oncology, neurology, and rare diseases are major market drivers. The successful commercialization of several gene therapies in recent years has demonstrated the potential for substantial returns on investment, attracting more funding for research and development in this field. Additionally, regulatory incentives, such as orphan drug designations and accelerated approvals, encourage the development of gene therapies for rare and severe conditions. Consumer behavior, particularly the growing demand for personalized medicine and treatments that offer durable to permanent cures, also propels the market forward. Moreover, collaborations between biotech firms, pharmaceutical companies, and academic institutions are fostering innovation and speeding the translation of gene therapy from research to clinical settings. These factors, combined with the increasing global capacity for biopharmaceutical manufacturing, ensure continued growth and expansion of gene therapy solutions, making it one of the most dynamic and transformative fields in modern medicine.

SCOPE OF STUDY:

The report analyzes the Gene Therapy market in terms of units by the following Segments, and Geographic Regions/Countries:

Segments:
Vector Type (Viral, Non-Viral); Application (Oncological Disorders, Rare Diseases, Cardiovascular Diseases, Neurological Disorders, Infectious Diseases, Other Applications)

Geographic Regions/Countries:
World; USA; Canada; Japan; China; Europe; France; Germany; Italy; UK; Rest of Europe; Asia-Pacific; Rest of World.

Select Competitors (Total 154 Featured) -

• Amgen, Inc.
• Alnylam Pharmaceuticals, Inc.
• Bionomics Ltd.
• BioMarin Pharmaceutical, Inc.
• AnGes, Inc.
• Amicus Therapeutics, Inc.
• Arrowhead Pharmaceuticals, Inc.
• bluebird bio, Inc.
• Advantagene, Inc.
• Biogen, Inc.
• Abeona Therapeutics
• Aptah
• Avrobio
• Arbor Biotechnologies, Inc.
• Biocardia, Inc.

TARIFF IMPACT FACTOR

Our new release incorporates impact of tariffs on geographical markets as we predict a shift in competitiveness of companies based on HQ country, manufacturing base, exports and imports (finished goods and OEM). This intricate and multifaceted market reality will impact competitors by artificially increasing the COGS, reducing profitability, reconfiguring supply chains, amongst other micro and macro market dynamics.

We are diligently following expert opinions of leading Chief Economists (14,949), Think Tanks (62), Trade & Industry bodies (171) worldwide, as they assess impact and address new market realities for their ecosystems. Experts and economists from every major country are tracked for their opinions on tariffs and how they will impact their countries.

We expect this chaos to play out over the next 2-3 months and a new world order is established with more clarity. We are tracking these developments on a real time basis.

As we release this report, U.S. Trade Representatives are pushing their counterparts in 183 countries for an early closure to bilateral tariff negotiations. Most of the major trading partners also have initiated trade agreements with other key trading nations, outside of those in the works with the United States. We are tracking such secondary fallouts as supply chains shift.

To our valued clients, we say, we have your back. We will present a simplified market reassessment by incorporating these changes!

APRIL 2025: NEGOTIATION PHASE

Our April release addresses the impact of tariffs on the overall global market and presents market adjustments by geography. Our trajectories are based on historic data and evolving market impacting factors.

JULY 2025 FINAL TARIFF RESET

Complimentary Update: Our clients will also receive a complimentary update in July after a final reset is announced between nations. The final updated version incorporates clearly defined Tariff Impact Analyses.

Reciprocal and Bilateral Trade & Tariff Impact Analyses:

USA
CHINA
MEXICO
CANADA
EU
JAPAN
INDIA
176 OTHER COUNTRIES.

Leading Economists - Our knowledge base tracks 14,949 economists including a select group of most influential Chief Economists of nations, think tanks, trade and industry bodies, big enterprises, and domain experts who are sharing views on the fallout of this unprecedented paradigm shift in the global econometric landscape. Most of our 16,491+ reports have incorporated this two-stage release schedule based on milestones.

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