Progressive Supranuclear Palsy- Pipeline Insight, 2025
Description
DelveInsight’s, “Progressive Supranuclear Palsy- Pipeline Insight, 2025” report provides comprehensive insights about 10+ companies and 12+ pipeline drugs in Progressive Supranuclear Palsy pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Geography Covered
Progressive Supranuclear Palsy: Overview
Progressive Supranuclear Palsy (PSP) is a rare neurodegenerative disorder caused by the accumulation of tau protein in the brain. It primarily affects movement, balance, speech, vision, and cognition. Early symptoms often include frequent falls, difficulty with eye movements (especially looking down), and stiffness in the neck. As the disease progresses, individuals may experience slurred speech, swallowing difficulties, and behavioral changes. PSP is often misdiagnosed as Parkinson's disease due to overlapping symptoms but lacks the significant tremors. Currently, there is no cure, and treatment focuses on symptom management and supportive care.
Progressive Supranuclear Palsy (PSP) is characterized by early postural instability, frequent falls, and difficulty with voluntary eye movements, especially looking down. Other symptoms include stiffness, slurred speech, swallowing difficulties, and a slow, stiff gait. Cognitive changes, such as apathy and impaired judgment, may also occur. Unlike Parkinson's, PSP lacks significant tremors and is resistant to dopaminergic therapy. PSP affects approximately 3-6 people per 100,000, typically after the age of 60. It is caused by abnormal deposits of tau protein in the brain, leading to neurodegeneration. PSP is characterized by difficulty with vertical eye movements, frequent falls, postural instability, and stiffness. It is often mistaken for Parkinson's disease or other neurological disorders due to overlapping symptoms. Current treatments focus on symptom management, including medications, therapy, and supportive care.
Certain factors may increase your risk of developing Progressive Supranuclear Palsy. These include genetic predisposition mutations or variations in the MAPT gene, which codes for the tau protein, may increase the risk. PSP typically occurs in individuals over the age of 60.Some studies suggest that exposure to certain toxins or chemicals may play a role, though evidence is limited. PSP is slightly more common in men than in women. Abnormal accumulation of tau protein in the brain is a hallmark, though the triggers for this dysfunction are unclear. The diagnosis of Progressive Supranuclear Palsy (PSP) is primarily clinical, based on a detailed medical history, symptom evaluation, and neurological examination. Key diagnostic features include difficulty with vertical eye movements, frequent falls, postural instability, and progressive stiffness. Brain imaging, such as MRI, may show midbrain atrophy (the ""hummingbird sign"") and exclude other conditions. Genetic testing for MAPT mutations may be considered in rare cases. Since no definitive test exists, PSP is often misdiagnosed, particularly in its early stages.
There is no cure for Progressive Supranuclear Palsy (PSP), and treatment focuses on managing symptoms and improving quality of life. Medications like levodopa may provide limited relief for stiffness and slowness, but their effects are often temporary. Physical and occupational therapy can help improve mobility, balance, and daily functioning. Speech therapy is beneficial for addressing speech and swallowing difficulties. Assistive devices, such as walkers and glasses with prisms, may aid in mobility and vision. Supportive care, including counseling and nutritional management, is essential as the disease progresses.
""Progressive Supranuclear Palsy- Pipeline Insight, 2025"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Progressive Supranuclear Palsy pipeline landscape is provided which includes the disease overview and Progressive Supranuclear Palsy treatment guidelines. The assessment part of the report embraces, in depth Progressive Supranuclear Palsy commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Progressive Supranuclear Palsy collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
This segment of the Progressive Supranuclear Palsy report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, II/III I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Progressive Supranuclear Palsy Emerging Drugs
Further product details are provided in the report……..
Progressive Supranuclear Palsy: Therapeutic Assessment
This segment of the report provides insights about the different Progressive Supranuclear Palsy drugs segregated based on following parameters that define the scope of the report, such as:
Progressive Supranuclear Palsy: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Progressive Supranuclear Palsy therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Progressive Supranuclear Palsy drugs.
Progressive Supranuclear Palsy Report Insights
Current Treatment Scenario and Emerging Therapies:
Geography Covered
- Global coverage
Progressive Supranuclear Palsy: Overview
Progressive Supranuclear Palsy (PSP) is a rare neurodegenerative disorder caused by the accumulation of tau protein in the brain. It primarily affects movement, balance, speech, vision, and cognition. Early symptoms often include frequent falls, difficulty with eye movements (especially looking down), and stiffness in the neck. As the disease progresses, individuals may experience slurred speech, swallowing difficulties, and behavioral changes. PSP is often misdiagnosed as Parkinson's disease due to overlapping symptoms but lacks the significant tremors. Currently, there is no cure, and treatment focuses on symptom management and supportive care.
Progressive Supranuclear Palsy (PSP) is characterized by early postural instability, frequent falls, and difficulty with voluntary eye movements, especially looking down. Other symptoms include stiffness, slurred speech, swallowing difficulties, and a slow, stiff gait. Cognitive changes, such as apathy and impaired judgment, may also occur. Unlike Parkinson's, PSP lacks significant tremors and is resistant to dopaminergic therapy. PSP affects approximately 3-6 people per 100,000, typically after the age of 60. It is caused by abnormal deposits of tau protein in the brain, leading to neurodegeneration. PSP is characterized by difficulty with vertical eye movements, frequent falls, postural instability, and stiffness. It is often mistaken for Parkinson's disease or other neurological disorders due to overlapping symptoms. Current treatments focus on symptom management, including medications, therapy, and supportive care.
Certain factors may increase your risk of developing Progressive Supranuclear Palsy. These include genetic predisposition mutations or variations in the MAPT gene, which codes for the tau protein, may increase the risk. PSP typically occurs in individuals over the age of 60.Some studies suggest that exposure to certain toxins or chemicals may play a role, though evidence is limited. PSP is slightly more common in men than in women. Abnormal accumulation of tau protein in the brain is a hallmark, though the triggers for this dysfunction are unclear. The diagnosis of Progressive Supranuclear Palsy (PSP) is primarily clinical, based on a detailed medical history, symptom evaluation, and neurological examination. Key diagnostic features include difficulty with vertical eye movements, frequent falls, postural instability, and progressive stiffness. Brain imaging, such as MRI, may show midbrain atrophy (the ""hummingbird sign"") and exclude other conditions. Genetic testing for MAPT mutations may be considered in rare cases. Since no definitive test exists, PSP is often misdiagnosed, particularly in its early stages.
There is no cure for Progressive Supranuclear Palsy (PSP), and treatment focuses on managing symptoms and improving quality of life. Medications like levodopa may provide limited relief for stiffness and slowness, but their effects are often temporary. Physical and occupational therapy can help improve mobility, balance, and daily functioning. Speech therapy is beneficial for addressing speech and swallowing difficulties. Assistive devices, such as walkers and glasses with prisms, may aid in mobility and vision. Supportive care, including counseling and nutritional management, is essential as the disease progresses.
""Progressive Supranuclear Palsy- Pipeline Insight, 2025"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Progressive Supranuclear Palsy pipeline landscape is provided which includes the disease overview and Progressive Supranuclear Palsy treatment guidelines. The assessment part of the report embraces, in depth Progressive Supranuclear Palsy commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Progressive Supranuclear Palsy collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Progressive Supranuclear Palsy R&D. The therapies under development are focused on novel approaches to treat/improve Progressive Supranuclear Palsy.
This segment of the Progressive Supranuclear Palsy report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, II/III I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Progressive Supranuclear Palsy Emerging Drugs
- AMX0035: Amylyx Pharmaceuticals
- TPN-101: Transposon Therapeutics, Inc.
Further product details are provided in the report……..
Progressive Supranuclear Palsy: Therapeutic Assessment
This segment of the report provides insights about the different Progressive Supranuclear Palsy drugs segregated based on following parameters that define the scope of the report, such as:
- Major Players in Progressive Supranuclear Palsy
- Phases
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
- Intravenous
- Subcutaneous
- Oral
- Intramuscular
- Molecule Type
- Monoclonal antibody
- Small molecule
- Peptide
- Product Type
Progressive Supranuclear Palsy: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Progressive Supranuclear Palsy therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Progressive Supranuclear Palsy drugs.
Progressive Supranuclear Palsy Report Insights
- Progressive Supranuclear Palsy Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Progressive Supranuclear Palsy drugs?
- How many Progressive Supranuclear Palsy drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Progressive Supranuclear Palsy?
- What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Progressive Supranuclear Palsy therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Progressive Supranuclear Palsy and their status?
- What are the key designations that have been granted to the emerging drugs?
- Amylyx Pharmaceuticals
- Transposon Therapeutics, Inc
- Ferrer International
- Novartis Pharmaceuticals
- TauC3 Biologics
- AMX0035
- TPN-101
- FNP-223
- NIO 752
- TBL-100
Table of Contents
60 Pages
- Introduction
- Executive Summary
- Progressive Supranuclear Palsy: Overview
- Causes
- Mechanism of Action
- Signs and Symptoms
- Diagnosis
- Disease Management
- Pipeline Therapeutics
- Comparative Analysis
- Therapeutic Assessment
- Assessment by Product Type
- Assessment by Stage and Product Type
- Assessment by Route of Administration
- Assessment by Stage and Route of Administration
- Assessment by Molecule Type
- Assessment by Stage and Molecule Type
- Progressive Supranuclear Palsy– DelveInsight’s Analytical Perspective
- Late Stage Products (Phase III)
- Comparative Analysis
- Drug Name: Company Name
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II/III)
- Comparative Analysis
- AMX0035: Amylyx Pharmaceuticals
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I/II)
- Comparative Analysis
- Drug Name: Company Name
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- Comparative Analysis
- Drug Name: Company Name
- Product Description
- Research and Development
- Product Development Activities
- Drug profiles in the detailed report…..
- Inactive Products
- Comparative Analysis
- Progressive Supranuclear Palsy Key Companies
- Progressive Supranuclear Palsy Key Products
- Progressive Supranuclear Palsy- Unmet Needs
- Progressive Supranuclear Palsy- Market Drivers and Barriers
- Progressive Supranuclear Palsy- Future Perspectives and Conclusion
- Progressive Supranuclear Palsy Analyst Views
- Progressive Supranuclear Palsy Key Companies
- Appendix
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