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Immune Checkpoint Inhibitors Market

Published Feb 19, 2026
Length 151 Pages
SKU # CMI20951043

Description

Immune checkpoint inhibitors are a part of immuno-oncology therapies, which involves use of patients’ immune system to fight against cancer. Immuno-oncology uses novel immunotherapies such as immune checkpoint inhibitors that boost the immune system of patients. These therapies target the immune system of the body instead of the tumors and enable the immune system to recognize and target cancer cells. Immune checkpoint inhibitors are immunotherapy products that block the proteins, which stop immune system from attacking the cancer cells. These drugs block certain checkpoint proteins such as CTLA-4, PD-1, and PD-L1. Manufacturers are engaged in research and development of immune checkpoint inhibitors as standalone therapies as well as in combination with other immuno-oncology products. Immune checkpoint inhibitors work against a wide variety of cancer, which include non-small cell lung cancer, lymphoma, skin cancer, breast cancer, and others. Depending on the functioning of these therapies they are further classified into subtypes such as programmed death receptor-1 (PD-1) inhibitors, programmed death-ligand 1 (PD-L1) inhibitors, and cytotoxic t-lymphocyte antigen 4 (CTLA-4) inhibitors. Commercially available immune checkpoint inhibitors include Iplimumab, Nivolumab, Rituximab, Blinatumomab, Proleukin, Gardasil, and Kymriah.

Market Dynamics

The rise in prevalence of cancer is expected to drive the global immune checkpoint inhibitors market. For instance, according to the American Cancer Society, in 2022, 1,918,030 new cancer cases and 609,360 cancer deaths are projected to occur in the United States, including approximately 350 deaths per day from lung cancer, the leading cause of cancer death. In 2022, there will be approximately 4,820,000 and 2,370,000 new cancer cases, and 3,210,000 and 640,000 cancer deaths in China and the USA, respectively. Estimated numbers of new cancer cases and deaths in 2022 (In 2022, there will be an estimated 1.9 million new cancer cases diagnosed and 609,360 cancer deaths in the United States.)

Key features of the study

This report provides an in-depth analysis of the global immune checkpoint inhibitors market, and provides market size (US$ Million) and compound annual growth rate (CAGR%) for the forecast period (2022–2030), considering 2021 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global immune checkpoint inhibitors market based on the following parameters – company highlights, products portfolio, key highlights, financial performance, and strategies
Key companies covered as a part of this study include Bristol-Myers Squibb Company, Merck & Co., Inc., F. Hoffmann-La Roche AG, AstraZeneca Plc, Novartis International AG, ImmunOs Therapeutics AG, Immutep Ltd., NewLink Genetics Corporation, Ono Pharmaceutical Co., Ltd., and Pfizer, Inc.
Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
The global immune checkpoint inhibitors market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global immune checkpoint inhibitors market
Market Segmentation

By Drug Class
  • Programmed Death Receptor-1 (PD-1) Inhibitors
  • Pembrolizumab (Keytruda)
  • Nivolumab (Opdivo)
  • Cemiplimab (Libtayo)
  • Others
  • Programmed Death-Ligand 1 (PD-L1) Inhibitors
  • Atezolizumab (Tecentriq)
  • Avelumab (Bavencio)
  • Durvalumab (Imfinzi)
  • CTL-4 Checkpoint Inhibitor
  • Ipilimumab (Yervoy)
  • Indoleamine-2,3-dioxygenase (IDO) Inhibitors
  • Lymphocyte-Activation Gene 3 Inhibitors
By Cancer Type
  • Lung Cancer
  • Head & Neck Cancer
  • Skin Cancer
  • Melanoma
  • Merkel Cell Carcinoma
  • Blood Cancer
  • Lymphoma
  • Bladder Cancer
  • Urothelial Carcinoma
  • Renal/Kidney Cancer
  • Colorectal Cancer
  • Breast Cancer
  • Others
By Distribution Channel
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
By Region
  • North America
  • U.S.
  • Canada
  • Latin America
  • Brazil
  • Argentina
  • Mexico
  • Rest of Latin America
  • Europe
  • Germany
  • U.K.
  • Spain
  • France
  • Italy
  • Russia
  • Rest of Europe
  • Asia Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • ASEAN
  • Rest of Asia Pacific
  • Middle East & Africa
  • GCC Countries
  • Israel
  • Rest of Middle East & Africa
Key Players
  • Bristol-Myers Squibb Company
  • Merck & Co., Inc.
  • Hoffmann-La Roche AG
  • AstraZeneca Plc.
  • Novartis International AG
  • ImmunOs Therapeutics AG
  • Immutep Ltd.
  • NewLink Genetics Corporation
  • Ono Pharmaceutical Co., Ltd.
  • Pfizer, Inc.

Table of Contents

151 Pages
1. Research Objectives and Assumptions
Research Objectives
Assumptions
Abbreviations
2. Market Purview
Report Description
Market Definition and Scope
Executive Summary
Market Snapshot, By Drug Class
Market Snapshot, By Cancer Type
Market Snapshot, By Distribution Channel
Market Snapshot, By Region
Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Drivers
Restraints
Market Opportunities
Impact Analysis
Epidemiology
Collaborations & Partnerships
Major FDA Approvals & Product Launch Scenario
Pipeline Analysis
Regulatory Scenario
Reimbursement Scenario
PEST Analysis
Porter’s Five Forces Analysis
4. Global Immune Checkpoint Inhibitors Market, By Drug Class, 2026 – 2033, (USD Mn)
Introduction
Market Share Analysis, 2026 and 2033 (%)
Y-o-Y Growth Analysis, 2026 – 2033
Segment Trends
Programmed Death Receptor-1 (PD-1) Inhibitors
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Pembrolizumab (Keytruda)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Nivolumab (Opdivo)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Cemiplimab (Libtayo)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Others
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Programmed Death-Ligand 1 (PD-L1) Inhibitors
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Atezolizumab (Tecentriq)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Avelumab (Bavencio)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Durvalumab (Imfinzi)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
CTL-4 Checkpoint Inhibitor
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Ipilimumab (Yervoy)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Indoleamine-2,3-dioxygenase (IDO) Inhibitors
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Lymphocyte-Activation Gene 3 Inhibitors
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
5. Global Immune Checkpoint Inhibitors Market, By Cancer Type, 2026 – 2033, (USD Mn)
Introduction
Market Share Analysis, 2026 and 2033 (%)
Y-o-Y Growth Analysis, 2026 – 2033
Segment Trends
Lung Cancer
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Head & Neck Cancer
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Skin Cancer (Melanoma and Merkel Cell Carcinoma)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Blood Cancer (Lymphoma)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Bladder Cancer (Urothelial Carcinoma)
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Renal/Kidney Cancer
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Colorectal Cancer
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Breast Cancer
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Others
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
6. Global Immune Checkpoint Inhibitors Market, By Distribution Channel, 2026 – 2033, (USD Mn)
Introduction
Market Share Analysis, 2026 and 2033 (%)
Y-o-Y Growth Analysis, 2026 – 2033
Segment Trends
Hospital Pharmacies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Retail Pharmacies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
Online Pharmacies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2026–2033, (USD Mn)
7. Global Immune Checkpoint Inhibitors Market, By Region, 2026 – 2033, (USD Mn)
Introduction
Market Share Analysis, By Region, 2026 and 2033 (%)
Y-o-Y Growth Analysis, For Regions, 2026–2033
Regional Trends
North America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2026 – 2033, (USD Mn)
U.S.
Canada
Latin America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2026 – 2033, (USD Mn)
Brazil
Mexico
Argentina
Rest of Latin America
Europe
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2026 – 2033, (USD Mn)
U.K.
Germany
Italy
France
Spain
Russia
Rest of Europe
Asia Pacific
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2026 – 2033, (USD Mn)
China
India
Japan
ASEAN
Australia
South Korea
Rest of Asia Pacific
Middle East
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2026 – 2033, (USD Mn)
GCC
Israel
Rest of Middle East
Africa
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Cancer Type, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2026 - 2033, (USD Mn)
Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2026 – 2033, (USD Mn)
North Africa
Central Africa
South Africa
8. Competitive Landscape
Heat Map Analysis
Company Profiles
Bristol-Myers Squibb Company
Company Highlights
Product Portfolio
Key Highlights
Financial Performance
Strategies
Merck & Co., Inc.
Company Introduction
Product Portfolio
Key Developments
Financial Performance
Strategies
F. Hoffmann-La Roche AG
Company Introduction
Product Portfolio
Key Developments
Financial Performance
Strategies
AstraZeneca Plc
Company Introduction
Product Portfolio
Key Developments
Financial Performance
Strategies
Novartis International AG
Company Introduction
Product Portfolio
Key Developments
Financial Performance
Strategies
ImmunOs Therapeutics AG
Company Introduction
Product Portfolio
Key Developments
Financial Performance
Strategies
Immutep Ltd.
Company Introduction
Product Portfolio
Key Developments
Financial Performance
Strategies
NewLink Genetics Corporation
Company Introduction
Product Portfolio
Key Developments
Financial Performance
Strategies
Ono Pharmaceutical Co., Ltd.
Company Introduction
Product Portfolio
Key Developments
Financial Performance
Strategies
Pfizer Inc.
Company Introduction
Product Portfolio
Key Developments
Financial Performance
Strategies
9. Section
References
Research Methodology
About Us and Sales Contact
How Do Licenses Work?
Request A Sample
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