Sanger sequencing, also known as chain termination or dideoxy sequencing, is a method for DNA sequencing based on the selective incorporation of chain-terminating dideoxynucleotides by DNA polymerase during in vitro DNA replication. This technique, developed by a British biochemist, Mr. Frederick Sanger in 1977, revolutionized DNA sequencing and enabled rapid progress in genetics and genomics. Sanger sequencing produces high-quality DNA sequences in both directions and is considered the gold standard for DNA sequencing.
Market Dynamics:
The global sanger sequencing market is predominantly driven by the increasing demand for accurate and cost-effective DNA sequencing across various industries such as healthcare, biotechnology, academic research, etc. Continuous technological advancements leading to automation and higher throughput are expanding the applications of Sanger sequencing. For example, many next-generation sequencing platforms rely on short Sanger reads for assembly. However, high capital investment requirements and complex workflow pose challenges for market growth. Emerging sequencing technologies threaten to disrupt the market through lower costs and higher capacity. Nonetheless, sanger sequencing is expected to remain relevant in niche applications that require long and accurate reads. Market players are focused on product portfolio expansion and geographic expansion through collaborations.
Key Features of the Study:
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