Third-generation sequencing (also known as long-read sequencing) is a class of DNA sequencing methods. Third-generation sequencing works by reading nucleotide sequences at a single molecule level, which is capable of producing substantially much longer reads than the current methods. It has the ability to generate longer reads than second-generation sequencing, also known as next-generation sequencing. Moreover, third-generation sequencing has emerged as the ‘gold-standard’ technology for cDNA sequencing.
Market Dynamics:
Rising prevalence of chronic and infectious diseases, increasing applications in clinical diagnosis, growing applications of genomics, rise in focus on drug discovery and development, and growing efficiency compared to traditional technologies are major factors expected to propel growth of the global third generation sequencing market.
For instance, with the rise in burden of chronic disease, the usage or demand for third-generation sequencing technology-based devices is also increasing with a rapid pace. TGS technologies can be utilized in studying gene expression of chronic diseases as it help in understanding their molecular mechanisms. According to the World Health Organization (WHO), September 2023 report, non-communicable diseases (NCDs) kill 41 million individuals each year, equivalent to 74% of all deaths worldwide. Cardiovascular diseases account for most NCD deaths, or 17.9 million people annually, followed by cancers (9.3 million), chronic respiratory diseases (4.1 million), and diabetes (2.0 million).
Moreover, according to the Centers for Disease Control and Prevention (CDC), chronic diseases such as heart disease, cancer, and diabetes are the leading causes of death and disability in the U.S.
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