Bone Graft and Substitutes Market, by Product Type (Bone Grafts (Allografts and Xenografts) and Bone Graft Substitutes (Ceramics, Composites, Polymers, Demineralized Bone Matrix, Bone Morphogenetic Proteins, and Others)), by Application (Spinal Fusion, De

Bone Graft and Substitutes Market, by Product Type (Bone Grafts (Allografts and Xenografts) and Bone Graft Substitutes (Ceramics, Composites, Polymers, Demineralized Bone Matrix, Bone Morphogenetic Proteins, and Others)), by Application (Spinal Fusion, Dental Bone Grafts, Craniomaxillofacial, Joint Reconstruction, Trauma & Extremities, and Oncology), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Outlook, and Opportunity Analysis, 2022 - 2028

The incorporation of a bone graft can be defined as a procedure of interdigitation and envelopment of the donor bone tissue with the new bone deposited by the recipient. It is a versatile that replaces the lost bone tissue, enhances bone growth using natural mechanisms. The natural bone graft are the most successful types of bone grafts and are considered to be the gold standard for replacement of missing bones. Bone grafts are in used in various purposes such as to fill the cavities resulting from cysts, tumors, or other causes, to stimulate the healing of fractures that have failed to heal after an initial treatment attempt, and others.
Market Dynamics
According to the Journal of Materials Science and Materials in Medicine, 2014, bone grafting frequency is the second most frequent tissue transplantation technique carried out globally after blood transfusion. The 2014 statistics reported in the Journal of Materials Science and Materials in Medicine, states that over 2 million bone grafting procedures are performed annually with over 500,000 graft implant procedures carried out in the U.S. itself. This is attributed to the ease of use and handling of new devices, improved safety profile, time advantages, intraoperative costs as well as the adaptability to a variety of clinical challenges.
The global bone graft, substitutes and membrane market is expected to witness a significant growth over the forecast period, owing to adoption of new technologies by manufacturers for development of innovative and novel bone graft substitutes. This includes the launches of novel growth factor enhanced grafts that improves the quality of grafts in terms of post-surgical recovery. For instance, in 2015, Cerapedics, a privately owned orthobiologics company received the U.S. FDA approval for i-Factor, which is a peptide enhanced graft that is used in cervical discectomy and fusion. The graft was based on small peptide (P-15) technology that helps in supporting bone growth through cell attachment and activation
Key features of the study:
This report provides in-depth analysis of the global bone graft and substitutes market, market size (US$ Mn), and compound annual growth rate (CAGR %) over the forecast period (2022 - 2028), considering 2021 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new technology launches or approval, market trends, regional outlook, and competitive strategies adopted by leading players
It profiles leading players in the global bone graft and substitutes market based on the following parameters – company overview, financial performance, technology portfolio, geographical presence, distribution strategies, key developments, and strategies
Key players covered as a part of this study include Ace Surgical Supply Co., Inc., NovaBone Product, LLC., Exactech, Inc., Medtronic Plc., LifeNet Health, Zimmer Biomet Holdings, Inc., Stryker Corporation., BioHorizons Implant Systems, Inc., Globus Medical, Inc., RTI Surgical, Inc., Geistlich Pharma, Megagen, Novadip Biosciences, Mesoblast Ltd., Alphatec Spine, Inc., Institut Straumann AG, NuVasive, Inc., OsteoMed LLC, KYERON Medical Innovations, ORTHOFIX INTERNATIONAL N.V., Johnson & Johnson, Bone Therapeutics SA, K2M Group Holdings, Inc., and OsteoNovus
Insights from this report would allow marketers and management authorities of companies to make informed decision with respect to future technology launches, government initiatives, technological upgradation, market expansion, and marketing tactics
The global bone graft and substitutes market report caters to various stakeholders in this market, including investors, technology manufacturers, distributors, and suppliers for global bone graft and substitutes market, research and consulting firms, new entrants, and financial analysts
Detailed Segmentation:
Global bone graft and substitutes market, by product type:
Bone Grafts
Allografts
Xenografts
Bone Graft Substitutes
Ceramics
Composites
Polymers
Demineralized Bone Matrix
Bone Morphogenetic Proteins
Others
Global bone graft and substitutes market, by application:
Spinal Fusion
Dental Bone Grafts
Craniomaxillofacial
Joint Reconstruction
Trauma & Extremities
Oncology
Global bone graft and substitutes market, by region:
North America
By Country:
U.S.
Canada
By Product Type:
Bone Grafts
Allografts
Xenografts
Bone Graft Substitutes
Ceramics
Composites
Polymers
Demineralized Bone Matrix
Bone Morphogenetic Proteins
Others
By Application:
Spinal Fusion
Dental Bone Grafts
Craniomaxillofacial
Joint Reconstruction
Trauma & Extremities
Oncology
Europe
By Country:
U.K.
Germany
Italy
Spain
France
Russia
Rest of Europe
By Product Type:
Bone Grafts
Allografts
Xenografts
Bone Graft Substitutes
Ceramics
Composites
Polymers
Demineralized Bone Matrix
Bone Morphogenetic Proteins
Others
By Application:
Spinal Fusion
Dental Bone Grafts
Craniomaxillofacial
Joint Reconstruction
Trauma & Extremities
Oncology
Asia Pacific
By Country:
Australia
India
China
Japan
ASEAN
South Korea
Rest of Asia Pacific
By Product Type:
Bone Grafts
Allografts
Xenografts
Bone Graft Substitutes
Ceramics
Composites
Polymers
Demineralized Bone Matrix
Bone Morphogenetic Proteins
Others
By Application:
Spinal Fusion
Dental Bone Grafts
Craniomaxillofacial
Joint Reconstruction
Trauma & Extremities
Oncology
Latin America
By Country:
Brazil
Mexico
Argentina
Rest of Latin America
By Product Type:
Bone Grafts
Allografts
Xenografts
Bone Graft Substitutes
Ceramics
Composites
Polymers
Demineralized Bone Matrix
Bone Morphogenetic Proteins
Others
By Application:
Spinal Fusion
Dental Bone Grafts
Craniomaxillofacial
Joint Reconstruction
Trauma & Extremities
Oncology
Middle East
By Country:
GCC
Israel
Rest of Middle East
By Product Type:
Bone Grafts
Allografts
Xenografts
Bone Graft Substitutes
Ceramics
Composites
Polymers
Demineralized Bone Matrix
Bone Morphogenetic Proteins
Others
By Application:
Spinal Fusion
Dental Bone Grafts
Craniomaxillofacial
Joint Reconstruction
Trauma & Extremities
Oncology
Africa
By Country/Region:
South Africa
Central Africa
North Africa
By Product Type:
Bone Grafts
Allografts
Xenografts
Bone Graft Substitutes
Ceramics
Composites
Polymers
Demineralized Bone Matrix
Bone Morphogenetic Proteins
Others
By Application:
Spinal Fusion
Dental Bone Grafts
Craniomaxillofacial
Joint Reconstruction
Trauma & Extremities
Oncology
Company Profiles
Ace Surgical Supply Co., Inc.*
Company Overview
Technology Portfolio
Financial Performance
Recent Highlights
Strategies
NovaBone Product, LLC.
Exactech, Inc.
Medtronic Plc.
LifeNet Health
Zimmer Biomet Holdings, Inc.
Stryker Corporation.
BioHorizons Implant Systems, Inc.
Globus Medical, Inc.
RTI Surgical, Inc
Geistlich Pharma
Megagen
Novadip Biosciences
Mesoblast Ltd.
Alphatec Spine, Inc.
Institut Straumann AG
NuVasive, Inc.
OsteoMed LLC
KYERON Medical Innovations
ORTHOFIX INTERNATIONAL N.V.
Johnson & Johnson
Bone Therapeutics SA
K2M Group Holdings, Inc.
OsteoNovus
“*” marked represents similar segmentation in other categories in the respective section.


1. Research Objective and assumption
Research Objectives
Assumptions
Abbreviations
2. Market Purview
Report Description
Market Definition and Scope
Executive Summary
Market Snippet By Product Type
Market Snippet By Application
Market Snippet By Region
Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Drivers
Restraints
Market Opportunities
Regulatory Scenario
Industry Trend
Merger and Acquisitions
New Product Approvals/Launch
Promotion and Marketing Initiatives
4. Global Bone Graft and Substitutes Market, By Product type, 2017 - 2028 (US$ Million)
Introduction
Market Share Analysis, 2022 and 2028 (%)
Y-O-Y Growth Analysis, 2017 - 2028
Segment Trends
Bone Grafts
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Allograft
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Xenograft
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Bone Graft Substitutes
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Ceramic
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Composite
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Polymer
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Bone Morphogenetic Proteins (BMP)
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Demineralized Bone Matrix (DBM)
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Others
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
5. Global Bone Graft and Substitutes Market, By Application, 2017 - 2028 (US$ Million)
Introduction
Market Share Analysis, 2022 and 2028 (%)
Y-O-Y Growth Analysis, 2017 - 2028
Segment Trends
Spinal Fusion
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Dental
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Craniomaxillofacial
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Joint Reconstruction
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
Trauma and Extremities
Introduction
Market Size and Forecast, and Y-O-Y Growth, 2017 - 2028, (US$ Million)
6. Global Bone Graft and Substitutes, By Regions, 2017 - 2028 (US$ Million)
Introduction
Market Share Analysis, By Region, 2022 and 2028 (%)
Y-o-Y Growth Analysis, For Regions, 2017 - 2028
Regional Trends
North America
Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
U.S.
Canada
Europe
Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
Germany
U.K.
France
Italy
Spain
Russia
Rest of Europe
Asia Pacific
Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
China
India
Japan
Australia
South Korea
ASEAN
Rest of APAC
Latin America
Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
Brazil
Mexico
Rest of Latin America
Middle East
Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
GCC
Israel
Rest of Middle East
Africa
Market Size and Forecast, By Product Type, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Application, 2017 - 2028 (US$ Mn)
Market Size and Forecast, By Country, 2017 - 2028 (US$ Mn)
South Africa
North Africa
Central Africa
7. Competitive Landscape
Heat Map Analysis
Company Profiles
Medtronic plc
Company Overview
Product Portfolio
Financial Performance
Recent Developments/Updates
Future Plans
RTI Surgical, Inc.
Company Overview
Product Portfolio
Financial Performance
Recent Developments/Updates
Future Plans
Stryker Corporation
Company Overview
Product Portfolio
Financial Performance
Recent Developments/Updates
Future Plans
Zimmer Biomet Holdings
Company Overview
Product Portfolio
Financial Performance
Recent Developments/Updates
Future Plans
Orthofix International N.V.
Company Overview
Product Portfolio
Financial Performance
Recent Developments/Updates
Future Plans
DePuySynthes
Company Overview
Product Portfolio
Financial Performance
Recent Developments/Updates
Future Plans
Bone Therapeutics
Company Overview
Product Portfolio
Financial Performance
Recent Developments/Updates
Future Plans
NuVasive Inc.
Company Overview
Product Portfolio
Financial Performance
Recent Developments/Updates
Future Plans
Institute Straumann AG
Company Overview
Product Portfolio
Financial Performance
Recent Developments/Updates
Future Plans
Analyst Views
8. Section
References
Research Methodology
About us and Sales Contact
*Browse 29 market data tables and 37 figures on "Global Bone Grafts and Substitutes Market” - Global forecast to 2028”.

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